NO870759L - 9alfa, 11beta-substituerte og 11beta-substituerte oestraner - Google Patents
9alfa, 11beta-substituerte og 11beta-substituerte oestranerInfo
- Publication number
- NO870759L NO870759L NO870759A NO870759A NO870759L NO 870759 L NO870759 L NO 870759L NO 870759 A NO870759 A NO 870759A NO 870759 A NO870759 A NO 870759A NO 870759 L NO870759 L NO 870759L
- Authority
- NO
- Norway
- Prior art keywords
- substituted
- 11beta
- eastranes
- 9alfa
- beta
- Prior art date
Links
- 230000002254 contraceptive effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000002162 estranes Chemical class 0.000 abstract 1
- 230000001076 estrogenic effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0062—Estrane derivatives substituted in position 17 alfa not substituted in position 17 beta
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
- C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0096—Alkynyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Steroid Compounds (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Diaphragms For Electromechanical Transducers (AREA)
- Compounds Of Unknown Constitution (AREA)
- Liquid Crystal Substances (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Silicon Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/748,489 US4705783A (en) | 1985-06-25 | 1985-06-25 | 9α, 11β-substituted and 11β-substituted estranes |
PCT/US1986/001358 WO1987000175A1 (en) | 1985-06-25 | 1986-06-24 | 9alpha, 11beta-SUBSTITUTED AND 11beta-SUBSTITUTED ESTRANES |
Publications (2)
Publication Number | Publication Date |
---|---|
NO870759D0 NO870759D0 (no) | 1987-02-24 |
NO870759L true NO870759L (no) | 1987-02-24 |
Family
ID=25009663
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO870759A NO870759L (no) | 1985-06-25 | 1987-02-24 | 9alfa, 11beta-substituerte og 11beta-substituerte oestraner |
Country Status (9)
Country | Link |
---|---|
US (3) | US4705783A (no) |
EP (1) | EP0227813B1 (no) |
JP (1) | JPH0816117B2 (no) |
AT (1) | ATE68001T1 (no) |
DE (1) | DE3681786D1 (no) |
DK (1) | DK98087D0 (no) |
FI (1) | FI88509C (no) |
NO (1) | NO870759L (no) |
WO (1) | WO1987000175A1 (no) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0826062B2 (ja) * | 1986-10-10 | 1996-03-13 | ルーセル ウクラーフ | 9―α―ヒドロキシステロイド及びその製法 |
US5137882A (en) * | 1990-06-11 | 1992-08-11 | Holt Dennis A | Steroidal 3-acetic acid derivatives as 5-alpha-reductase inhibitors |
US5554603A (en) * | 1993-09-17 | 1996-09-10 | The United States Of America As Represented By The Department Of Health And Human Services | Orally active derivatives of 1,3,5(10)-estratriene |
US6083528A (en) * | 1995-09-28 | 2000-07-04 | Schering Aktiengesellschaft | Hormone replacement therapy method and hormone dispenser |
US5922349A (en) * | 1995-09-28 | 1999-07-13 | Schering Aktiengesellschaft | Hormone replacement therapy method and hormone dispenser |
US6551611B2 (en) | 1995-09-28 | 2003-04-22 | Schering Aktiengesellschaft | Hormone replacement therapy method |
US6054446A (en) | 1997-12-24 | 2000-04-25 | Sri International | Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use |
US6548491B2 (en) | 1997-12-24 | 2003-04-15 | Sri International | Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use |
US6503896B1 (en) | 1997-12-24 | 2003-01-07 | Sri International | Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use |
DE19906159A1 (de) * | 1999-02-09 | 2000-08-10 | Schering Ag | 16-Hydroxyestratriene als selektiv wirksame Estrogene |
US6958327B1 (en) | 1999-11-02 | 2005-10-25 | Schering, Ag | 18 Norsteroids as selectively active estrogens |
DE50014299D1 (de) * | 1999-11-02 | 2007-06-14 | Bayer Schering Pharma Ag | 18-nor-steroide als selektiv wirksame estrogene |
US20050282791A1 (en) * | 1999-11-02 | 2005-12-22 | Alexander Hillisch | 18-nor steroids as selectively active estrogens |
US8173628B2 (en) * | 2000-06-22 | 2012-05-08 | Northeastern University | Steroidal antiestrogens and antiandrogens and uses thereof |
US7041839B2 (en) * | 2000-06-22 | 2006-05-09 | Northeastern University | Steroidal antiestrogens and antiandrogens and uses thereof |
AU2001296872A1 (en) * | 2000-09-14 | 2002-03-26 | Accelerated Pharmaceuticals, Inc. | Method of making 7alpha-methyl-11beta-methoxy estradiol and related compounds with estrogenic activity |
DE10233723A1 (de) * | 2002-07-24 | 2004-02-12 | Schering Ag | Mikrobiologische Verfahren zur Herstellung von 7α-substituierten 11α-Hydroxysteroiden, daraus herstellbare 7α,17α-substituierte 11β-Halogensteroide, deren Herstellungsverfahren und Verwendung sowie pharmazeutische Präparate, die diese Verbindungen enthalten, sowie daraus herstellbare 7α-substituierte Estra-1,3,5(10)-triene |
EP1603933A2 (en) * | 2003-03-13 | 2005-12-14 | Nitromed, Inc. | Nitrosated and nitrosylated compounds, compositions and methods of use |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1074493A (en) * | 1963-06-12 | 1967-07-05 | Roussel Uclaf | Novel estrane derivatives and processes for preparing them |
BE649225A (no) * | 1963-06-12 | |||
FR5519M (no) * | 1966-06-07 | 1967-11-06 | ||
US3411567A (en) * | 1966-06-13 | 1968-11-19 | United Eng Foundry Co | Mold supporting structure for casting machine |
FR6854M (no) * | 1967-12-15 | 1969-04-08 | ||
US3980681A (en) * | 1969-11-21 | 1976-09-14 | Peter Job Sykes | Process for the preparation of 11-β-nitro-oxysteroids |
US3755574A (en) * | 1971-01-21 | 1973-08-28 | Roussel Uclaf | Estrogenic compositions comprising 11beta-alkoxy-gona-1,3,5(10)-trienes |
US3906096A (en) * | 1971-11-23 | 1975-09-16 | Roussel Uclaf | Novel 11{62 -alkoxy steroids |
US3755301A (en) * | 1972-06-23 | 1973-08-28 | Searle & Co | Manufacture of 11-alkyl steroids |
NL7405626A (nl) * | 1974-04-26 | 1975-10-28 | Akzo Nv | Nieuwe 11-gesubstitueerde steroiden van de oestraanreeks. |
NL7613248A (nl) * | 1976-11-26 | 1978-05-30 | Akzo Nv | Werkwijze voor het bereiden van nieuwe steroid- esters. |
DE3248434A1 (de) * | 1982-12-23 | 1984-06-28 | Schering AG, 1000 Berlin und 4709 Bergkamen | Verfahren zur herstellung von 3,11(alpha)-dihydroxy-1,3,5(10)-oestratrien-derivaten |
-
1985
- 1985-06-25 US US06/748,489 patent/US4705783A/en not_active Ceased
-
1986
- 1986-06-24 JP JP61503719A patent/JPH0816117B2/ja not_active Expired - Lifetime
- 1986-06-24 AT AT86904572T patent/ATE68001T1/de not_active IP Right Cessation
- 1986-06-24 EP EP86904572A patent/EP0227813B1/en not_active Expired - Lifetime
- 1986-06-24 WO PCT/US1986/001358 patent/WO1987000175A1/en active IP Right Grant
- 1986-06-24 DE DE8686904572T patent/DE3681786D1/de not_active Expired - Lifetime
-
1987
- 1987-02-24 NO NO870759A patent/NO870759L/no unknown
- 1987-02-25 FI FI870808A patent/FI88509C/fi not_active IP Right Cessation
- 1987-02-25 DK DK098087A patent/DK98087D0/da not_active Application Discontinuation
- 1987-08-24 US US07/088,802 patent/US4859370A/en not_active Expired - Fee Related
-
1989
- 1989-11-09 US US07/434,849 patent/USRE34136E/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0227813B1 (en) | 1991-10-02 |
DE3681786D1 (de) | 1991-11-07 |
US4705783A (en) | 1987-11-10 |
JPH0816117B2 (ja) | 1996-02-21 |
NO870759D0 (no) | 1987-02-24 |
DK98087A (da) | 1987-02-25 |
FI870808A (fi) | 1987-02-25 |
EP0227813A1 (en) | 1987-07-08 |
FI870808A0 (fi) | 1987-02-25 |
DK98087D0 (da) | 1987-02-25 |
WO1987000175A1 (en) | 1987-01-15 |
FI88509B (fi) | 1993-02-15 |
USRE34136E (en) | 1992-12-01 |
US4859370A (en) | 1989-08-22 |
JPS63500101A (ja) | 1988-01-14 |
FI88509C (fi) | 1993-05-25 |
ATE68001T1 (de) | 1991-10-15 |
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