NO870759L - 9alfa, 11beta-substituerte og 11beta-substituerte oestraner - Google Patents

9alfa, 11beta-substituerte og 11beta-substituerte oestraner

Info

Publication number
NO870759L
NO870759L NO870759A NO870759A NO870759L NO 870759 L NO870759 L NO 870759L NO 870759 A NO870759 A NO 870759A NO 870759 A NO870759 A NO 870759A NO 870759 L NO870759 L NO 870759L
Authority
NO
Norway
Prior art keywords
substituted
11beta
eastranes
9alfa
beta
Prior art date
Application number
NO870759A
Other languages
English (en)
Other versions
NO870759D0 (no
Inventor
David Franklin Crowe
Masato Tanabe
Richard H Paters
Original Assignee
Stanford Res Inst Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stanford Res Inst Int filed Critical Stanford Res Inst Int
Publication of NO870759D0 publication Critical patent/NO870759D0/no
Publication of NO870759L publication Critical patent/NO870759L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0059—Estrane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0062—Estrane derivatives substituted in position 17 alfa not substituted in position 17 beta
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0081—Substituted in position 17 alfa and 17 beta
    • C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0096—Alkynyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Liquid Crystal Substances (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Silicon Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NO870759A 1985-06-25 1987-02-24 9alfa, 11beta-substituerte og 11beta-substituerte oestraner NO870759L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/748,489 US4705783A (en) 1985-06-25 1985-06-25 9α, 11β-substituted and 11β-substituted estranes
PCT/US1986/001358 WO1987000175A1 (en) 1985-06-25 1986-06-24 9alpha, 11beta-SUBSTITUTED AND 11beta-SUBSTITUTED ESTRANES

Publications (2)

Publication Number Publication Date
NO870759D0 NO870759D0 (no) 1987-02-24
NO870759L true NO870759L (no) 1987-02-24

Family

ID=25009663

Family Applications (1)

Application Number Title Priority Date Filing Date
NO870759A NO870759L (no) 1985-06-25 1987-02-24 9alfa, 11beta-substituerte og 11beta-substituerte oestraner

Country Status (9)

Country Link
US (3) US4705783A (no)
EP (1) EP0227813B1 (no)
JP (1) JPH0816117B2 (no)
AT (1) ATE68001T1 (no)
DE (1) DE3681786D1 (no)
DK (1) DK98087D0 (no)
FI (1) FI88509C (no)
NO (1) NO870759L (no)
WO (1) WO1987000175A1 (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0826062B2 (ja) * 1986-10-10 1996-03-13 ルーセル ウクラーフ ９―α―ヒドロキシステロイド及びその製法
US5137882A (en) * 1990-06-11 1992-08-11 Holt Dennis A Steroidal 3-acetic acid derivatives as 5-alpha-reductase inhibitors
US5554603A (en) * 1993-09-17 1996-09-10 The United States Of America As Represented By The Department Of Health And Human Services Orally active derivatives of 1,3,5(10)-estratriene
US6083528A (en) * 1995-09-28 2000-07-04 Schering Aktiengesellschaft Hormone replacement therapy method and hormone dispenser
US5922349A (en) * 1995-09-28 1999-07-13 Schering Aktiengesellschaft Hormone replacement therapy method and hormone dispenser
US6551611B2 (en) 1995-09-28 2003-04-22 Schering Aktiengesellschaft Hormone replacement therapy method
US6054446A (en) 1997-12-24 2000-04-25 Sri International Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
US6548491B2 (en) 1997-12-24 2003-04-15 Sri International Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
US6503896B1 (en) 1997-12-24 2003-01-07 Sri International Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
DE19906159A1 (de) * 1999-02-09 2000-08-10 Schering Ag 16-Hydroxyestratriene als selektiv wirksame Estrogene
US6958327B1 (en) 1999-11-02 2005-10-25 Schering, Ag 18 Norsteroids as selectively active estrogens
DE50014299D1 (de) * 1999-11-02 2007-06-14 Bayer Schering Pharma Ag 18-nor-steroide als selektiv wirksame estrogene
US20050282791A1 (en) * 1999-11-02 2005-12-22 Alexander Hillisch 18-nor steroids as selectively active estrogens
US8173628B2 (en) * 2000-06-22 2012-05-08 Northeastern University Steroidal antiestrogens and antiandrogens and uses thereof
US7041839B2 (en) * 2000-06-22 2006-05-09 Northeastern University Steroidal antiestrogens and antiandrogens and uses thereof
AU2001296872A1 (en) * 2000-09-14 2002-03-26 Accelerated Pharmaceuticals, Inc. Method of making 7alpha-methyl-11beta-methoxy estradiol and related compounds with estrogenic activity
DE10233723A1 (de) * 2002-07-24 2004-02-12 Schering Ag Mikrobiologische Verfahren zur Herstellung von 7α-substituierten 11α-Hydroxysteroiden, daraus herstellbare 7α,17α-substituierte 11β-Halogensteroide, deren Herstellungsverfahren und Verwendung sowie pharmazeutische Präparate, die diese Verbindungen enthalten, sowie daraus herstellbare 7α-substituierte Estra-1,3,5(10)-triene
EP1603933A2 (en) * 2003-03-13 2005-12-14 Nitromed, Inc. Nitrosated and nitrosylated compounds, compositions and methods of use

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1074493A (en) * 1963-06-12 1967-07-05 Roussel Uclaf Novel estrane derivatives and processes for preparing them
BE649225A (no) * 1963-06-12
FR5519M (no) * 1966-06-07 1967-11-06
US3411567A (en) * 1966-06-13 1968-11-19 United Eng Foundry Co Mold supporting structure for casting machine
FR6854M (no) * 1967-12-15 1969-04-08
US3980681A (en) * 1969-11-21 1976-09-14 Peter Job Sykes Process for the preparation of 11-β-nitro-oxysteroids
US3755574A (en) * 1971-01-21 1973-08-28 Roussel Uclaf Estrogenic compositions comprising 11beta-alkoxy-gona-1,3,5(10)-trienes
US3906096A (en) * 1971-11-23 1975-09-16 Roussel Uclaf Novel 11{62 -alkoxy steroids
US3755301A (en) * 1972-06-23 1973-08-28 Searle & Co Manufacture of 11-alkyl steroids
NL7405626A (nl) * 1974-04-26 1975-10-28 Akzo Nv Nieuwe 11-gesubstitueerde steroiden van de oestraanreeks.
NL7613248A (nl) * 1976-11-26 1978-05-30 Akzo Nv Werkwijze voor het bereiden van nieuwe steroid- esters.
DE3248434A1 (de) * 1982-12-23 1984-06-28 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur herstellung von 3,11(alpha)-dihydroxy-1,3,5(10)-oestratrien-derivaten

Also Published As

Publication number Publication date
EP0227813B1 (en) 1991-10-02
DE3681786D1 (de) 1991-11-07
US4705783A (en) 1987-11-10
JPH0816117B2 (ja) 1996-02-21
NO870759D0 (no) 1987-02-24
DK98087A (da) 1987-02-25
FI870808A (fi) 1987-02-25
EP0227813A1 (en) 1987-07-08
FI870808A0 (fi) 1987-02-25
DK98087D0 (da) 1987-02-25
WO1987000175A1 (en) 1987-01-15
FI88509B (fi) 1993-02-15
USRE34136E (en) 1992-12-01
US4859370A (en) 1989-08-22
JPS63500101A (ja) 1988-01-14
FI88509C (fi) 1993-05-25
ATE68001T1 (de) 1991-10-15

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