NO843909L - Substituerte 2(1h)-kinazolinon-1-alkansyrer og -estere samt fremgangsmaate for deres fremstilling - Google Patents

Substituerte 2(1h)-kinazolinon-1-alkansyrer og -estere samt fremgangsmaate for deres fremstilling

Info

Publication number
NO843909L
NO843909L NO843909A NO843909A NO843909L NO 843909 L NO843909 L NO 843909L NO 843909 A NO843909 A NO 843909A NO 843909 A NO843909 A NO 843909A NO 843909 L NO843909 L NO 843909L
Authority
NO
Norway
Prior art keywords
methyl
quinazolinone
formula
hydrogen
propionic acid
Prior art date
Application number
NO843909A
Other languages
English (en)
Norwegian (no)
Inventor
Victor T Bandurco
Seymour D Levine
Alfonso J Tobia
Dennis M Mulvey
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/537,233 external-priority patent/US4555571A/en
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of NO843909L publication Critical patent/NO843909L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/80—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Steroid Compounds (AREA)
NO843909A 1983-09-29 1984-09-28 Substituerte 2(1h)-kinazolinon-1-alkansyrer og -estere samt fremgangsmaate for deres fremstilling NO843909L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/537,233 US4555571A (en) 1983-09-29 1983-09-29 Substituted 2(1H)-quinazolinone-1-alkanoic acids and esters
US06/627,138 US4656267A (en) 1983-09-29 1984-07-02 Substituted 2(1H)-quinazolinone-1-alkanoic acids and esters

Publications (1)

Publication Number Publication Date
NO843909L true NO843909L (no) 1985-04-01

Family

ID=27065423

Family Applications (1)

Application Number Title Priority Date Filing Date
NO843909A NO843909L (no) 1983-09-29 1984-09-28 Substituerte 2(1h)-kinazolinon-1-alkansyrer og -estere samt fremgangsmaate for deres fremstilling

Country Status (5)

Country Link
US (1) US4656267A (el)
EP (1) EP0138491A3 (el)
DK (1) DK468084A (el)
GR (1) GR80506B (el)
NO (1) NO843909L (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751304A (en) * 1984-09-26 1988-06-14 Ortho Pharmaceutical Corporation Process for preparing 5,6-dialkoxy-4-alkyl-2(1H)-quinazolinones
DE19506739A1 (de) * 1995-02-27 1996-08-29 Bayer Ag [3-Amino]-tetrahydrocarbazol-propansäureester
EP2147679B1 (en) 2001-07-25 2014-06-25 Raptor Pharmaceutical, Inc. Compositions for blood-brain barrier transport
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
WO2008011032A1 (en) * 2006-07-17 2008-01-24 Amgen Inc. Quinazoline and pyridopyrimidine derivatives as p38 kinase inhibitors
WO2008036682A2 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
DK2398500T3 (da) 2009-02-20 2019-05-13 2 Bbb Medicines B V Glutathion-baseret lægemiddelafgivelsessystem
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
US10111873B1 (en) 2018-01-17 2018-10-30 King Saud University Dihydropyrimidinone derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2118315C3 (de) * 1970-04-20 1975-04-03 Sumitomo Chemical Co., Ltd., Osaka (Japan) 2-(1H)-Chinazolinonderivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US4001238A (en) * 1976-02-18 1977-01-04 Bristol-Myers Company 1,3,4-oxadiazole amides
US4146712A (en) * 1976-03-11 1979-03-27 Ciba-Geigy Corporation Process for the manufacture of coumarin dyes
JPS5795966A (en) * 1980-12-04 1982-06-15 Sumitomo Chem Co Ltd Novel 2(1h)-quinazolinone derivative
US4490374A (en) * 1982-09-30 1984-12-25 Ortho Pharmaceutical Corporation 5,6-Dialkoxy-3,4-optionally substituted-2(1H)quinazolinones, composition and method of use
US4555571A (en) * 1983-09-29 1985-11-26 Ortho Pharmaceutical Corporation Substituted 2(1H)-quinazolinone-1-alkanoic acids and esters
US4555570A (en) * 1983-09-29 1985-11-26 Ortho Pharmaceutical Corporation Substituted 4-alkyl-2-(1H) quinazolinone-1-alkanoic acid derivatives

Also Published As

Publication number Publication date
GR80506B (en) 1985-01-30
DK468084D0 (da) 1984-09-28
US4656267A (en) 1987-04-07
EP0138491A3 (en) 1986-01-15
DK468084A (da) 1985-03-30
EP0138491A2 (en) 1985-04-24

Similar Documents

Publication Publication Date Title
US3594480A (en) Nitrogen heterocycles for therapeutic administration
US4098786A (en) Benzodiazepin derivatives
US3920636A (en) Quinazoline compounds
US4029792A (en) (2-Imidazolin-2-ylamino) substituted -quinoxalines and -quinazolines as antihypertensive agents
CS201040B2 (en) Method of producing etherified hydroxy-benzo-diheterocyclic compounds
IE41539B1 (en) Chroman derivatives
RU2001910C1 (ru) Способ получени хинолинового производного
NZ202471A (en) Heterocyclic derivatives and pharmaceutical compositions having cardiotonic and/or antihypertensive properties
NO843909L (no) Substituerte 2(1h)-kinazolinon-1-alkansyrer og -estere samt fremgangsmaate for deres fremstilling
EP1484301B1 (en) PROCESS FOR PRODUCING trans-4-AMINO-1-CYCLOHEXANECARBOXYLIC ACID DERIVATIVE
EP0227450A2 (en) Substituted 5,6-Dialkoxyquinazoline Derivatives
JPH0692371B2 (ja) 新規複素環誘導体、その製法およびこれらを含有し、アルド−ス還元酵素抑制剤として特に有用な医薬の製法
JPS61286367A (ja) ベンズアゼピン誘導体
US4555571A (en) Substituted 2(1H)-quinazolinone-1-alkanoic acids and esters
NZ206823A (en) N-piperazinylalkanoylanilides and pharmaceutical compositions
US5084456A (en) Oxazolopyridine compounds
US4639518A (en) Substituted quinazolinediones
NO773300L (no) Fremgangsmaate for fremstilling av nye eddiksyrederivater
NO843908L (no) Fremgangsmaare for fremstilling av 4-alkyl-2(1h)-kinazolinon-1-alkansyrederivater
HU179391B (en) Process for producing thiasolo-square bracket-2,3-b-square bracket closed-quinasoline derivatives
US3949081A (en) 4-Carbamoyl-1-benzazepines as antiinflammatory agents
NL8002071A (nl) 2-hydroxy-5-(1-hydroxy-2-piperazinylethyl)- benzoee- zuurderivaten, werkwijze voor de bereiding daarvan, alsmede farmaceutische preparaten die deze bevatten.
US3793322A (en) 1,4-disubstituted piperazines
EP0243982A1 (en) 1-acyl-2,3-dihydro-4(1H)-quinolinone-4-oxime derivative, process for the production thereof, pharmaceutical composition and intermediates
US5071849A (en) Dihydropyrimidothiazine derivatives