NO842765L - Modulering av animalske cellulaere responser med preparater innehollende 8-substituerte guaninderivater - Google Patents

Modulering av animalske cellulaere responser med preparater innehollende 8-substituerte guaninderivater

Info

Publication number
NO842765L
NO842765L NO84842765A NO842765A NO842765L NO 842765 L NO842765 L NO 842765L NO 84842765 A NO84842765 A NO 84842765A NO 842765 A NO842765 A NO 842765A NO 842765 L NO842765 L NO 842765L
Authority
NO
Norway
Prior art keywords
modulation
preparations containing
cellular responses
substituted guanine
guanine derivatives
Prior art date
Application number
NO84842765A
Other languages
English (en)
Other versions
NO174215C (no
NO174215B (no
Inventor
Michael G Goodman
William O Weigle
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/439,846 external-priority patent/US4539205A/en
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of NO842765L publication Critical patent/NO842765L/no
Publication of NO174215B publication Critical patent/NO174215B/no
Publication of NO174215C publication Critical patent/NO174215C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
NO842765A 1982-11-09 1984-07-06 Fremgangsmåte for modulering av animalske cellulære responser in vitro med preparater inneholdende 8-substituerte guaninderivater NO174215C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/439,846 US4539205A (en) 1982-11-09 1982-11-09 Modulation of animal cellular responses with compositions containing 8-substituted guanine derivatives
US06/546,679 US4643992A (en) 1982-11-09 1983-11-01 Modulation of animal cellular responses with compositions containing 8-substituted guanine derivatives
PCT/US1983/001722 WO1984001898A1 (en) 1982-11-09 1983-11-07 Modulation of animal cellular responses with compositions containng 8-substituted guanine derivatives

Publications (3)

Publication Number Publication Date
NO842765L true NO842765L (no) 1984-07-06
NO174215B NO174215B (no) 1993-12-20
NO174215C NO174215C (no) 1994-03-30

Family

ID=27032191

Family Applications (1)

Application Number Title Priority Date Filing Date
NO842765A NO174215C (no) 1982-11-09 1984-07-06 Fremgangsmåte for modulering av animalske cellulære responser in vitro med preparater inneholdende 8-substituerte guaninderivater

Country Status (15)

Country Link
US (1) US4643992A (no)
EP (1) EP0112632B1 (no)
AU (1) AU568325B2 (no)
CA (1) CA1236401A (no)
DE (1) DE3382156D1 (no)
DK (1) DK167898B1 (no)
ES (1) ES527138A0 (no)
FI (1) FI87733C (no)
GR (1) GR78733B (no)
IE (1) IE56701B1 (no)
IL (1) IL70164A (no)
NO (1) NO174215C (no)
NZ (1) NZ206208A (no)
PT (1) PT77636B (no)
WO (1) WO1984001898A1 (no)

Families Citing this family (47)

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US5476659A (en) * 1982-11-09 1995-12-19 The Scripps Research Institute Cancerous B cell treatment using substituted nucleoside derivatives
US4849411A (en) * 1982-11-09 1989-07-18 Scripps Clinic And Research Foundation Modulation of animal cellular responses with compositions containing 8-substituted guanine derivatives
US5093318A (en) * 1983-11-01 1992-03-03 Scripps Clinic And Research Foundation Immunostimulating guanosine derivatives and their pharmaceutical compositions
US5166141A (en) * 1983-11-01 1992-11-24 Scripps Clinic And Research Foundation Immunostimulating 7-deaza-7-oxa- and 7-deaza-7-oxo-analogs of 8-substituted-guanine-9-(1'-beta-D-aldoglycosidyl) derivatives and methods of treating test animals
US4900675A (en) * 1983-11-01 1990-02-13 Scripps Clinic And Research Foundation Modulation of animal cellular responses with compositions containing isoxanthopterin-8-(1'-β-aldoglycosidyl) derivatives
FR2560212B1 (fr) * 1984-02-24 1989-12-29 Unicet Anticorps monoclonaux contre l'interferon a2 et hybridomes produisant de tels anticorps
US5011828A (en) * 1985-11-15 1991-04-30 Michael Goodman Immunostimulating guanine derivatives, compositions and methods
ZA869297B (en) * 1985-12-13 1987-11-25 Scripps Clinic Res Modulation of animal cellular responses with compositions containing isoxanthopterin-8-(1'-beta-aldoglycosidyl)derivatives
US6060459A (en) * 1987-10-28 2000-05-09 Pro-Neuron, Inc. Enhancing blood cell count with oxypurine nucleosides
US4880784A (en) * 1987-12-21 1989-11-14 Brigham Young University Antiviral methods utilizing ribofuranosylthiazolo[4,5-d]pyrimdine derivatives
US4902985A (en) * 1988-02-25 1990-02-20 Raytheon Company Microwave reflectiion amplifiers having increased bandwidth
GB2216416B (en) * 1988-03-11 1992-06-24 Sandoz Ltd Nucleobase source for the stimulation of the immune system
AU3578189A (en) * 1988-04-27 1989-11-24 Immunomedics Inc. Improved radiotherapy
AU5845594A (en) * 1992-11-13 1994-06-08 Scripps Research Institute, The Cancerous b cell treatment using substituted nucleoside derivatives
US5786359A (en) * 1994-05-27 1998-07-28 The Scripps Research Institute N9 alkyl or aralkyl derivatives of 7, 8-disubstituted guanines
US5441942A (en) * 1994-05-27 1995-08-15 The Scripps Research Institute 2'3'-dideoxy-2',3'-didehydro-7,8-disubstituted guanosines and their immunostimulative effect
US6338963B1 (en) 1994-07-25 2002-01-15 Neotherapeutics, Inc. Use of carbon monoxide dependent guanylyl cyclase modifiers to stimulate neuritogenesis
US20030100520A1 (en) * 1997-01-21 2003-05-29 Philip Needleman Immunological process and constructs for increasing the hdl cholesterol concentration by dna vaccination
AU3786299A (en) 1998-05-04 1999-11-23 Neotherapeutics, Inc. Novel serotonin-like 9-substituted hypoxanthine and methods of use
US6562801B1 (en) * 1999-04-15 2003-05-13 Board Of Regents, The University Of Texas System PpGpp and pppGpp as immunomodulatory agents
US6288069B1 (en) 1999-11-16 2001-09-11 Neotherapeutics, Inc. Use of 9-substituted hypoxanthine derivatives to stimulate regeneration of nervous tissue
US6407237B1 (en) 2001-02-21 2002-06-18 Neotherapeutics, Inc. Crystal forms of 9-substituted hypoxanthine derivatives
US6849735B1 (en) * 2000-06-23 2005-02-01 Merck Eprova Ag Methods of synthesis for 9-substituted hypoxanthine derivatives
US6630490B2 (en) 2000-07-07 2003-10-07 Neotherapeutics, Inc. Methods for treatment of disease-induced peripheral neuropathy and related conditions
US20030138769A1 (en) * 2000-08-16 2003-07-24 Birkett Ashley J. Immunogenic HBc chimer particles having enhanced stability
US6759427B2 (en) 2001-04-20 2004-07-06 Spectrum Pharmaceuticals, Inc. Synthesis and methods of use of tetrahydroindolone analogues and derivatives
JP2005509591A (ja) * 2001-06-15 2005-04-14 リバファーム・インコーポレイテッド ヌクレオシドワクチンアジュバント
US20030055249A1 (en) * 2001-07-17 2003-03-20 Fick David B. Synthesis and methods of use of pyrimidine analogues and derivatives
US20030175863A1 (en) * 2001-08-15 2003-09-18 Birkett Ashley J. Influenza immunogen and vaccine
US7361352B2 (en) * 2001-08-15 2008-04-22 Acambis, Inc. Influenza immunogen and vaccine
US7321033B2 (en) * 2001-11-27 2008-01-22 Anadys Pharmaceuticals, Inc. 3-B-D-ribofuranosylthiazolo [4,5-d] pyrimidine nucleosides and uses thereof
US7351413B2 (en) * 2002-02-21 2008-04-01 Lorantis, Limited Stabilized HBc chimer particles as immunogens for chronic hepatitis
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Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1174077A (en) * 1967-02-18 1969-12-10 Ajinomoto Kk Process for Preparing 8-Mercaptopurine Derivatives

Also Published As

Publication number Publication date
EP0112632B1 (en) 1991-02-06
FI87733B (fi) 1992-11-13
NZ206208A (en) 1987-03-31
DK334884A (da) 1984-07-06
AU2330284A (en) 1984-06-04
AU568325B2 (en) 1987-12-24
DK167898B1 (da) 1994-01-03
IL70164A0 (en) 1984-02-29
NO174215C (no) 1994-03-30
GR78733B (no) 1984-10-02
NO174215B (no) 1993-12-20
FI87733C (fi) 1993-02-25
FI842748A (fi) 1984-07-09
DK334884D0 (da) 1984-07-06
US4643992A (en) 1987-02-17
PT77636B (en) 1986-03-19
IL70164A (en) 1988-06-30
DE3382156D1 (de) 1991-03-14
PT77636A (en) 1983-12-01
CA1236401A (en) 1988-05-10
EP0112632A3 (en) 1985-01-23
EP0112632A2 (en) 1984-07-04
FI842748A0 (fi) 1984-07-09
ES8601301A1 (es) 1985-11-01
WO1984001898A1 (en) 1984-05-24
ES527138A0 (es) 1985-11-01
IE832605L (en) 1984-05-09
IE56701B1 (en) 1991-11-06

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