NO830468L - Pantenolderivater. - Google Patents
Pantenolderivater.Info
- Publication number
- NO830468L NO830468L NO830468A NO830468A NO830468L NO 830468 L NO830468 L NO 830468L NO 830468 A NO830468 A NO 830468A NO 830468 A NO830468 A NO 830468A NO 830468 L NO830468 L NO 830468L
- Authority
- NO
- Norway
- Prior art keywords
- panthenol
- zinc
- hexane
- aluminum
- compound
- Prior art date
Links
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims abstract description 13
- 229910052782 aluminium Inorganic materials 0.000 claims abstract description 13
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims abstract description 12
- 229910052725 zinc Inorganic materials 0.000 claims abstract description 12
- 239000011701 zinc Substances 0.000 claims abstract description 12
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims description 25
- 150000001875 compounds Chemical class 0.000 claims description 22
- 235000004866 D-panthenol Nutrition 0.000 claims description 19
- 239000011703 D-panthenol Substances 0.000 claims description 19
- 229960003949 dexpanthenol Drugs 0.000 claims description 19
- SNPLKNRPJHDVJA-UHFFFAOYSA-N dl-panthenol Chemical compound OCC(C)(C)C(O)C(=O)NCCCO SNPLKNRPJHDVJA-UHFFFAOYSA-N 0.000 claims description 8
- 238000000034 method Methods 0.000 claims description 4
- 230000000699 topical effect Effects 0.000 abstract description 9
- 238000004519 manufacturing process Methods 0.000 abstract description 8
- 239000003814 drug Substances 0.000 abstract description 7
- 239000004411 aluminium Substances 0.000 abstract 1
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 39
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 15
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 12
- 238000002360 preparation method Methods 0.000 description 10
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 9
- 239000000499 gel Substances 0.000 description 9
- 239000000203 mixture Substances 0.000 description 9
- 238000003756 stirring Methods 0.000 description 9
- 239000007789 gas Substances 0.000 description 7
- -1 isopro-!|' pyyl Chemical group 0.000 description 7
- 239000003921 oil Substances 0.000 description 7
- 239000000843 powder Substances 0.000 description 6
- 230000001681 protective effect Effects 0.000 description 6
- 238000010992 reflux Methods 0.000 description 6
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 5
- 206010052428 Wound Diseases 0.000 description 5
- 208000027418 Wounds and injury Diseases 0.000 description 5
- 239000012876 carrier material Substances 0.000 description 5
- 229940101267 panthenol Drugs 0.000 description 5
- 235000020957 pantothenol Nutrition 0.000 description 5
- 239000011619 pantothenol Substances 0.000 description 5
- 239000002904 solvent Substances 0.000 description 5
- MCULRUJILOGHCJ-UHFFFAOYSA-N triisobutylaluminium Chemical compound CC(C)C[Al](CC(C)C)CC(C)C MCULRUJILOGHCJ-UHFFFAOYSA-N 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 4
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 4
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 4
- 125000003545 alkoxy group Chemical group 0.000 description 4
- 125000000217 alkyl group Chemical group 0.000 description 4
- 238000001816 cooling Methods 0.000 description 4
- HQWPLXHWEZZGKY-UHFFFAOYSA-N diethylzinc Chemical compound CC[Zn]CC HQWPLXHWEZZGKY-UHFFFAOYSA-N 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 3
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- SMZOGRDCAXLAAR-UHFFFAOYSA-N aluminium isopropoxide Chemical compound [Al+3].CC(C)[O-].CC(C)[O-].CC(C)[O-] SMZOGRDCAXLAAR-UHFFFAOYSA-N 0.000 description 3
- 235000014113 dietary fatty acids Nutrition 0.000 description 3
- 239000002552 dosage form Substances 0.000 description 3
- 239000000194 fatty acid Substances 0.000 description 3
- 229930195729 fatty acid Natural products 0.000 description 3
- 150000004665 fatty acids Chemical class 0.000 description 3
- 230000035876 healing Effects 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 239000007858 starting material Substances 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
- VBICKXHEKHSIBG-UHFFFAOYSA-N 1-monostearoylglycerol Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCC(O)CO VBICKXHEKHSIBG-UHFFFAOYSA-N 0.000 description 2
- 229910002016 Aerosil® 200 Inorganic materials 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- 239000000443 aerosol Substances 0.000 description 2
- RDOXTESZEPMUJZ-UHFFFAOYSA-N anisole Chemical compound COC1=CC=CC=C1 RDOXTESZEPMUJZ-UHFFFAOYSA-N 0.000 description 2
- 229910052786 argon Inorganic materials 0.000 description 2
- 239000012298 atmosphere Substances 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 125000004432 carbon atom Chemical group C* 0.000 description 2
- MVPPADPHJFYWMZ-UHFFFAOYSA-N chlorobenzene Chemical compound ClC1=CC=CC=C1 MVPPADPHJFYWMZ-UHFFFAOYSA-N 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000004817 gas chromatography Methods 0.000 description 2
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 2
- 229930195733 hydrocarbon Natural products 0.000 description 2
- 150000002430 hydrocarbons Chemical class 0.000 description 2
- 239000011261 inert gas Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- 235000013336 milk Nutrition 0.000 description 2
- 210000004080 milk Anatomy 0.000 description 2
- 230000007935 neutral effect Effects 0.000 description 2
- 239000011541 reaction mixture Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000000454 talc Substances 0.000 description 2
- 229910052623 talc Inorganic materials 0.000 description 2
- 239000006208 topical dosage form Substances 0.000 description 2
- CYRMSUTZVYGINF-UHFFFAOYSA-N trichlorofluoromethane Chemical compound FC(Cl)(Cl)Cl CYRMSUTZVYGINF-UHFFFAOYSA-N 0.000 description 2
- 229940029284 trichlorofluoromethane Drugs 0.000 description 2
- 239000011787 zinc oxide Substances 0.000 description 2
- WSLDOOZREJYCGB-UHFFFAOYSA-N 1,2-Dichloroethane Chemical compound ClCCCl WSLDOOZREJYCGB-UHFFFAOYSA-N 0.000 description 1
- 206010002153 Anal fissure Diseases 0.000 description 1
- 208000016583 Anus disease Diseases 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- 241000700198 Cavia Species 0.000 description 1
- 206010011985 Decubitus ulcer Diseases 0.000 description 1
- 206010015150 Erythema Diseases 0.000 description 1
- OTMSDBZUPAUEDD-UHFFFAOYSA-N Ethane Chemical compound CC OTMSDBZUPAUEDD-UHFFFAOYSA-N 0.000 description 1
- 208000009531 Fissure in Ano Diseases 0.000 description 1
- HSRJKNPTNIJEKV-UHFFFAOYSA-N Guaifenesin Chemical compound COC1=CC=CC=C1OCC(O)CO HSRJKNPTNIJEKV-UHFFFAOYSA-N 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 206010039580 Scar Diseases 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 206010042496 Sunburn Diseases 0.000 description 1
- 241001122767 Theaceae Species 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 239000002250 absorbent Substances 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 150000001338 aliphatic hydrocarbons Chemical class 0.000 description 1
- 230000002009 allergenic effect Effects 0.000 description 1
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical compound [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 150000004945 aromatic hydrocarbons Chemical class 0.000 description 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 229960000541 cetyl alcohol Drugs 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 125000004177 diethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 230000001804 emulsifying effect Effects 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- 231100000321 erythema Toxicity 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000003349 gelling agent Substances 0.000 description 1
- YQEMORVAKMFKLG-UHFFFAOYSA-N glycerine monostearate Natural products CCCCCCCCCCCCCCCCCC(=O)OC(CO)CO YQEMORVAKMFKLG-UHFFFAOYSA-N 0.000 description 1
- SVUQHVRAGMNPLW-UHFFFAOYSA-N glycerol monostearate Natural products CCCCCCCCCCCCCCCCC(=O)OCC(O)CO SVUQHVRAGMNPLW-UHFFFAOYSA-N 0.000 description 1
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 description 1
- 125000004051 hexyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 description 1
- 210000002540 macrophage Anatomy 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- UZKWTJUDCOPSNM-UHFFFAOYSA-N methoxybenzene Substances CCCCOC=C UZKWTJUDCOPSNM-UHFFFAOYSA-N 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000004570 mortar (masonry) Substances 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- 239000002674 ointment Substances 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 229940124531 pharmaceutical excipient Drugs 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- LMHHRCOWPQNFTF-UHFFFAOYSA-N s-propan-2-yl azepane-1-carbothioate Chemical compound CC(C)SC(=O)N1CCCCCC1 LMHHRCOWPQNFTF-UHFFFAOYSA-N 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 1
- 230000007306 turnover Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Dermatology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Cosmetics (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH89082 | 1982-02-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO830468L true NO830468L (no) | 1983-08-15 |
Family
ID=4197563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO830468A NO830468L (no) | 1982-02-12 | 1983-02-11 | Pantenolderivater. |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US4514338A (ja) |
| EP (1) | EP0086320B1 (ja) |
| JP (1) | JPS58148842A (ja) |
| KR (1) | KR840003606A (ja) |
| AT (1) | ATE16476T1 (ja) |
| AU (1) | AU559768B2 (ja) |
| BR (1) | BR8300681A (ja) |
| CA (1) | CA1191863A (ja) |
| CS (1) | CS238387B2 (ja) |
| DE (1) | DE3361182D1 (ja) |
| DK (1) | DK49783A (ja) |
| ES (1) | ES8403103A1 (ja) |
| FI (1) | FI830207L (ja) |
| GR (1) | GR77415B (ja) |
| HU (1) | HU188529B (ja) |
| IE (1) | IE54559B1 (ja) |
| IL (1) | IL67849A (ja) |
| MC (1) | MC1501A1 (ja) |
| NO (1) | NO830468L (ja) |
| NZ (1) | NZ203186A (ja) |
| PH (1) | PH18734A (ja) |
| PT (1) | PT76231B (ja) |
| ZA (1) | ZA83767B (ja) |
| ZW (1) | ZW3883A1 (ja) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0155334A1 (en) * | 1984-03-21 | 1985-09-25 | Richardson Vicks Limited | Manufacture of pantyl/d-panthenol mixtures |
| US5227164A (en) * | 1990-01-29 | 1993-07-13 | Lundmark Larry D | Hair treatment composition and method |
| US5041285A (en) * | 1990-01-29 | 1991-08-20 | Larry D. Lundmark | Method of treating the hair with an allanoyoin-panthenol product |
| US5217812A (en) * | 1990-06-25 | 1993-06-08 | E. I. Du Pont De Nemours And Company | Extrudable and primerless adhesives and products therefrom |
| US20060189893A1 (en) * | 2005-01-06 | 2006-08-24 | Diamics, Inc. | Systems and methods for detecting abnormal cells |
| US20060161076A1 (en) * | 2005-01-06 | 2006-07-20 | Diamics, Inc. | Systems and methods for collection of cell clusters |
| CA3143557A1 (en) | 2019-12-16 | 2021-06-24 | Gentribio Inc. | External use composition comprising paeonol and panthenol or pharmaceutically acceptable salts thereof as active ingredients |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE840839C (de) * | 1948-06-25 | 1952-06-05 | Hoffmann La Roche | Verfahren zur Herstellung von Abkoemmlingen des 3-(2', 4'-Dioxy-3', 3'-dimethyl-butyryl)-aminopropanols-(1) |
-
1983
- 1983-01-03 AT AT83100001T patent/ATE16476T1/de active
- 1983-01-03 EP EP83100001A patent/EP0086320B1/de not_active Expired
- 1983-01-03 DE DE8383100001T patent/DE3361182D1/de not_active Expired
- 1983-01-14 CA CA000419481A patent/CA1191863A/en not_active Expired
- 1983-01-19 CS CS83381A patent/CS238387B2/cs unknown
- 1983-01-21 FI FI830207A patent/FI830207L/fi not_active Application Discontinuation
- 1983-01-26 US US06/461,093 patent/US4514338A/en not_active Expired - Fee Related
- 1983-02-04 ZW ZW38/83A patent/ZW3883A1/xx unknown
- 1983-02-04 ZA ZA83767A patent/ZA83767B/xx unknown
- 1983-02-04 DK DK49783A patent/DK49783A/da not_active Application Discontinuation
- 1983-02-04 NZ NZ203186A patent/NZ203186A/en unknown
- 1983-02-07 AU AU11169/83A patent/AU559768B2/en not_active Ceased
- 1983-02-07 IL IL67849A patent/IL67849A/xx unknown
- 1983-02-09 HU HU83442A patent/HU188529B/hu unknown
- 1983-02-09 PH PH28496A patent/PH18734A/en unknown
- 1983-02-10 BR BR8300681A patent/BR8300681A/pt unknown
- 1983-02-10 GR GR70460A patent/GR77415B/el unknown
- 1983-02-10 MC MC831621A patent/MC1501A1/xx unknown
- 1983-02-10 JP JP58019897A patent/JPS58148842A/ja active Pending
- 1983-02-11 IE IE286/83A patent/IE54559B1/en unknown
- 1983-02-11 ES ES519701A patent/ES8403103A1/es not_active Expired
- 1983-02-11 PT PT76231A patent/PT76231B/pt unknown
- 1983-02-11 KR KR1019830000549A patent/KR840003606A/ko not_active Application Discontinuation
- 1983-02-11 NO NO830468A patent/NO830468L/no unknown
-
1985
- 1985-01-14 US US06/690,919 patent/US4602036A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| IE54559B1 (en) | 1989-11-22 |
| CA1191863A (en) | 1985-08-13 |
| PT76231B (en) | 1986-01-27 |
| DK49783A (da) | 1983-08-13 |
| JPS58148842A (ja) | 1983-09-05 |
| ZW3883A1 (en) | 1983-08-31 |
| CS238387B2 (en) | 1985-11-13 |
| ES519701A0 (es) | 1984-03-16 |
| PT76231A (en) | 1983-03-01 |
| NZ203186A (en) | 1985-05-31 |
| IE830286L (en) | 1983-08-12 |
| ATE16476T1 (de) | 1985-11-15 |
| PH18734A (en) | 1985-09-16 |
| FI830207A0 (fi) | 1983-01-21 |
| HU188529B (en) | 1986-04-28 |
| IL67849A (en) | 1987-03-31 |
| ES8403103A1 (es) | 1984-03-16 |
| GR77415B (ja) | 1984-09-13 |
| MC1501A1 (fr) | 1983-11-17 |
| CS38183A2 (en) | 1984-12-14 |
| FI830207L (fi) | 1983-08-13 |
| AU559768B2 (en) | 1987-03-19 |
| EP0086320A1 (de) | 1983-08-24 |
| DE3361182D1 (de) | 1985-12-19 |
| DK49783D0 (da) | 1983-02-04 |
| AU1116983A (en) | 1983-08-18 |
| BR8300681A (pt) | 1983-11-08 |
| US4514338A (en) | 1985-04-30 |
| EP0086320B1 (de) | 1985-11-13 |
| ZA83767B (en) | 1983-10-26 |
| IL67849A0 (en) | 1983-06-15 |
| US4602036A (en) | 1986-07-22 |
| KR840003606A (ko) | 1984-09-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US3337402A (en) | Stable and palatable pharmaceutical composition | |
| US3740420A (en) | Pharmaceutical compositions with dimethyl sulfoxide | |
| NO830468L (no) | Pantenolderivater. | |
| CN1360572A (zh) | 维生素d3类似物 | |
| JPH0193517A (ja) | 医薬組成物 | |
| US4720494A (en) | Anticholinergic eucatropine esters and antiperspirant use thereof | |
| US4661519A (en) | Method for dermatological application | |
| CA1208564A (en) | Biotin c.sub.2-4-alkyl esters | |
| JPH05155814A (ja) | 乳酸アシレート、その塩類、それらの製造方法及びそれらを含む組成物 | |
| AU2001276567B2 (en) | Antifungal ketoconazole composition for topical use | |
| JPH06192062A (ja) | 皮膚外用剤 | |
| EP0244937A2 (en) | Pharmaceutical compositions containing (R,S) or (S) N-(2-[2-hydroxy-3-phenoxypropyl]aminoethyl)isobutyramide | |
| US4657923A (en) | Econazole-acexamic acid addition compound having antimycotic, cicatrizing and antiinflammatory activity | |
| AU2001276567A1 (en) | Antifungal ketoconazole composition for topical use | |
| AU664767B2 (en) | Composition for accelerating healing of wound | |
| JP4568488B2 (ja) | イソプロピルメチルフェノール配糖体 | |
| JPS6328070B2 (ja) | ||
| EP0367586B1 (en) | Primycin solutions | |
| CH665352A5 (fr) | Nouvelles compositions pharmaceutiques et cosmetiques contenant comme ingredient actif la dihydroxy-1,8 phenyl-10 anthrone-9, et procede de preparation de l'ingredient actif. | |
| CA1243682A (en) | Pharmaceutical addition compound between econazole and acexamic acid | |
| US3840599A (en) | 1,2-dichloropropionyl-(4'-chloro-2'-nitro)-anilide | |
| JPS59184125A (ja) | 抗糸状菌剤 | |
| NO852933L (no) | Fremgangsmaate ved fremstilling av en terapeutisk aktiv forbindelse. | |
| US3773760A (en) | 2-aminopyrimidine ethylmercurithiosalicylate | |
| GB2028130A (en) | Pharmaceutical wound-treating compositions containing allantoin |