NO782403L - Fremgangsmaate for fremstilling av benzylidenderivarter - Google Patents
Fremgangsmaate for fremstilling av benzylidenderivarterInfo
- Publication number
- NO782403L NO782403L NO782403A NO782403A NO782403L NO 782403 L NO782403 L NO 782403L NO 782403 A NO782403 A NO 782403A NO 782403 A NO782403 A NO 782403A NO 782403 L NO782403 L NO 782403L
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- benzyl
- radical
- formula
- procedure
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 10
- 238000002360 preparation method Methods 0.000 title claims description 3
- -1 BENZYLIDENE Chemical class 0.000 title 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 18
- 239000002253 acid Substances 0.000 claims description 5
- SDGHXWKVBZYHRR-UHFFFAOYSA-N 2-(1h-imidazol-2-ylsulfonyl)-1h-imidazole Chemical compound N=1C=CNC=1S(=O)(=O)C1=NC=CN1 SDGHXWKVBZYHRR-UHFFFAOYSA-N 0.000 claims description 4
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 4
- 150000001412 amines Chemical class 0.000 claims description 4
- 125000004432 carbon atom Chemical group C* 0.000 claims description 4
- 125000005843 halogen group Chemical group 0.000 claims description 3
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical compound [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 claims description 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims description 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims description 2
- 125000000217 alkyl group Chemical group 0.000 claims description 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims description 2
- 125000000649 benzylidene group Chemical group [H]C(=[*])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims description 2
- 229910052801 chlorine Inorganic materials 0.000 claims description 2
- 239000000460 chlorine Substances 0.000 claims description 2
- 125000000753 cycloalkyl group Chemical group 0.000 claims description 2
- 229910052731 fluorine Inorganic materials 0.000 claims description 2
- 239000011737 fluorine Substances 0.000 claims description 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 2
- 150000003254 radicals Chemical class 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims description 2
- 125000001424 substituent group Chemical group 0.000 claims description 2
- 229910021529 ammonia Inorganic materials 0.000 claims 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 1
- GRVDJDISBSALJP-UHFFFAOYSA-N methyloxidanyl Chemical compound [O]C GRVDJDISBSALJP-UHFFFAOYSA-N 0.000 claims 1
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 22
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 6
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 description 6
- 239000003208 petroleum Substances 0.000 description 5
- 239000003610 charcoal Substances 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- 150000001408 amides Chemical class 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
- WQDUMFSSJAZKTM-UHFFFAOYSA-N Sodium methoxide Chemical compound [Na+].[O-]C WQDUMFSSJAZKTM-UHFFFAOYSA-N 0.000 description 2
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 description 2
- DNSISZSEWVHGLH-UHFFFAOYSA-N butanamide Chemical compound CCCC(N)=O DNSISZSEWVHGLH-UHFFFAOYSA-N 0.000 description 2
- PFKFTWBEEFSNDU-UHFFFAOYSA-N carbonyldiimidazole Chemical compound C1=CN=CN1C(=O)N1C=CN=C1 PFKFTWBEEFSNDU-UHFFFAOYSA-N 0.000 description 2
- 230000008020 evaporation Effects 0.000 description 2
- 238000001704 evaporation Methods 0.000 description 2
- 239000005457 ice water Substances 0.000 description 2
- 230000008018 melting Effects 0.000 description 2
- 238000002844 melting Methods 0.000 description 2
- 239000002244 precipitate Substances 0.000 description 2
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 2
- 239000005711 Benzoic acid Substances 0.000 description 1
- 150000007513 acids Chemical class 0.000 description 1
- 229940125681 anticonvulsant agent Drugs 0.000 description 1
- 239000001961 anticonvulsive agent Substances 0.000 description 1
- 125000004429 atom Chemical group 0.000 description 1
- 235000010233 benzoic acid Nutrition 0.000 description 1
- JYYOBHFYCIDXHH-UHFFFAOYSA-N carbonic acid;hydrate Chemical compound O.OC(O)=O JYYOBHFYCIDXHH-UHFFFAOYSA-N 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 125000001153 fluoro group Chemical group F* 0.000 description 1
- 239000002198 insoluble material Substances 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 description 1
- AFDMODCXODAXLC-UHFFFAOYSA-N phenylmethanimine Chemical class N=CC1=CC=CC=C1 AFDMODCXODAXLC-UHFFFAOYSA-N 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/24—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7721445A FR2397397A2 (fr) | 1977-07-12 | 1977-07-12 | Preparation de derives benzylideniques |
Publications (1)
Publication Number | Publication Date |
---|---|
NO782403L true NO782403L (no) | 1979-01-15 |
Family
ID=9193280
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO782403A NO782403L (no) | 1977-07-12 | 1978-07-10 | Fremgangsmaate for fremstilling av benzylidenderivarter |
Country Status (16)
Country | Link |
---|---|
JP (1) | JPS5419953A (it) |
AT (1) | ATA501078A (it) |
AU (1) | AU3794678A (it) |
BE (1) | BE868949R (it) |
DE (1) | DE2830034A1 (it) |
DK (1) | DK310878A (it) |
ES (1) | ES471606A2 (it) |
FR (1) | FR2397397A2 (it) |
GB (1) | GB2001066A (it) |
IL (1) | IL55103A0 (it) |
IT (1) | IT1108730B (it) |
LU (1) | LU79946A1 (it) |
NL (1) | NL7807354A (it) |
NO (1) | NO782403L (it) |
SE (1) | SE7807729L (it) |
ZA (1) | ZA783940B (it) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH662664A5 (de) * | 1983-07-01 | 1987-10-15 | Loepfe Ag Geb | Regelverfahren und regeleinrichtung fuer eine vorrichtung oder vorrichtungsgruppe und vorrichtung mit einer regeleinrichtung. |
-
1977
- 1977-07-12 FR FR7721445A patent/FR2397397A2/fr active Granted
-
1978
- 1978-07-07 DE DE19782830034 patent/DE2830034A1/de not_active Withdrawn
- 1978-07-07 NL NL7807354A patent/NL7807354A/xx not_active Application Discontinuation
- 1978-07-07 IL IL55103A patent/IL55103A0/xx unknown
- 1978-07-10 NO NO782403A patent/NO782403L/no unknown
- 1978-07-10 ZA ZA00783940A patent/ZA783940B/xx unknown
- 1978-07-10 LU LU79946A patent/LU79946A1/xx unknown
- 1978-07-10 IT IT25496/78A patent/IT1108730B/it active
- 1978-07-11 JP JP8501678A patent/JPS5419953A/ja active Pending
- 1978-07-11 SE SE7807729A patent/SE7807729L/xx unknown
- 1978-07-11 AU AU37946/78A patent/AU3794678A/en active Pending
- 1978-07-11 GB GB7829520A patent/GB2001066A/en not_active Withdrawn
- 1978-07-11 DK DK783108A patent/DK310878A/da unknown
- 1978-07-11 AT AT501078A patent/ATA501078A/de not_active Application Discontinuation
- 1978-07-11 ES ES471606A patent/ES471606A2/es not_active Expired
- 1978-07-12 BE BE189243A patent/BE868949R/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
GB2001066A (en) | 1979-01-24 |
ATA501078A (de) | 1980-02-15 |
FR2397397A2 (fr) | 1979-02-09 |
IL55103A0 (en) | 1978-09-29 |
DE2830034A1 (de) | 1979-02-01 |
IT1108730B (it) | 1985-12-09 |
JPS5419953A (en) | 1979-02-15 |
AU3794678A (en) | 1980-01-17 |
DK310878A (da) | 1979-01-13 |
ZA783940B (en) | 1979-07-25 |
ES471606A2 (es) | 1979-02-16 |
IT7825496A0 (it) | 1978-07-10 |
SE7807729L (sv) | 1979-01-13 |
LU79946A1 (it) | 1978-12-12 |
NL7807354A (nl) | 1979-01-16 |
FR2397397B2 (it) | 1982-09-17 |
BE868949R (fr) | 1979-01-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2021202403B2 (en) | Methods of preparing cytotoxic benzodiazepine derivatives | |
DE69116576T2 (de) | Aromatische sulfonamidderivate, ihre verwendung als enzyminhibitoren und diese verbindungen enthaltende pharmazeutische zusammensetzungen | |
Black et al. | Metal Template Reactions. XXIII. Synthesis of Macrocyclic Amide and Ester Complexes Via 1, 1′-Oxalylbisisatin | |
US20240116915A1 (en) | Fluorine-containing pyrazole compound and method for producing same | |
RO117450B1 (ro) | Procedeu de preparare a 4,6-dicloro-pirimidinei | |
BR112012004161B1 (pt) | método para sintetizar uma piperazina neuroestimulativa | |
JPS62114957A (ja) | プロリルエンドペプチダ−ゼ阻害作用を有する新規ピロリジン誘導体およびその製法並びに用途 | |
NO782403L (no) | Fremgangsmaate for fremstilling av benzylidenderivarter | |
Okafor | Heterocyclic series. VII. Use of Kaufmann's reaction as a route to o-aminomercaptopyridines | |
NO178028B (no) | Fremgangsmåte ved fremstilling av 3-(L-pyroglutamyl)-L-tiazolidin-4-karboksylsyre samt derivater derav | |
JPH04234374A (ja) | ジケトピペラジン誘導体の製造方法 | |
Sun et al. | Growth and characterization of the nonlinear optical crystal: L‐arginine trifluoroacetate | |
Van der Eijk et al. | Optically active polyampholytes derived from L-and D-carbylanayl-L-histidine | |
CN107778224B (zh) | 一种贝曲西班中间体的制备方法 | |
SU728717A3 (ru) | Способ получени тиено 2,3-с или тиено 3,2-с -пиридинов | |
US2519530A (en) | Biotin aliphatic amides and method for their preparation | |
UA73472C2 (en) | A method for producing n-methyl-n-[(1s)-1-phenyl-2-((3s)-3-hydroxypyrrolidine-1-yl)ethyl]-2,2-diphenyl acetamide | |
BARNHURST | Dipolar ions related to taurine | |
Sarantakis et al. | 2-Fluoropyridine N-oxide and its reactions with amino-acid derivatives | |
ALILI et al. | SYNTHESIS OF N-BENZAMIDOMETHYL-4-TOLUENESULFONAMIDE BY TWO DIFFERENT SYNTHETIC METHODS | |
Nasakin et al. | Synthesis of substituted pyridines by reaction of tetracyanoethylated ketones with hydrochloric and hydrobromic acids | |
EP4105210A1 (en) | Fluorine-containing pyrimidine compound and production method therefor | |
JPH05202058A (ja) | 5,6,11,12−テトラチオテトラセンの製造方法 | |
US2506975A (en) | Synthesis of cystathionine and intermediate condensation products | |
JPH09169714A (ja) | ニトリルの製造方法 |