NO333106B1 - Sammensetninger som omfatter et antidiar±middel og et epotilon eller et epotilonderivat, samt anvendelse derav - Google Patents
Sammensetninger som omfatter et antidiar±middel og et epotilon eller et epotilonderivat, samt anvendelse derav Download PDFInfo
- Publication number
- NO333106B1 NO333106B1 NO20034094A NO20034094A NO333106B1 NO 333106 B1 NO333106 B1 NO 333106B1 NO 20034094 A NO20034094 A NO 20034094A NO 20034094 A NO20034094 A NO 20034094A NO 333106 B1 NO333106 B1 NO 333106B1
- Authority
- NO
- Norway
- Prior art keywords
- epothilone
- hydrogen
- formula
- alkyl
- inhibitor
- Prior art date
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
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- A—HUMAN NECESSITIES
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Landscapes
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- Medicinal Chemistry (AREA)
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- Gynecology & Obstetrics (AREA)
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- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
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US27715301P | 2001-03-19 | 2001-03-19 | |
US27720701P | 2001-03-20 | 2001-03-20 | |
PCT/EP2002/002977 WO2002074042A2 (en) | 2001-03-19 | 2002-03-18 | Combinations comprising an antidiarrheal agent and an epothilone or an epothilone derivative |
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NO20034094L NO20034094L (no) | 2003-09-15 |
NO20034094D0 NO20034094D0 (no) | 2003-09-15 |
NO333106B1 true NO333106B1 (no) | 2013-03-04 |
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NO20034094A NO333106B1 (no) | 2001-03-19 | 2003-09-15 | Sammensetninger som omfatter et antidiar±middel og et epotilon eller et epotilonderivat, samt anvendelse derav |
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US (1) | US7030147B2 (ko) |
EP (1) | EP1372650B1 (ko) |
JP (2) | JP2004519493A (ko) |
KR (1) | KR100863089B1 (ko) |
CN (1) | CN100540001C (ko) |
AT (1) | ATE414514T1 (ko) |
AU (1) | AU2002251067B2 (ko) |
BR (1) | BR0208142A (ko) |
CA (1) | CA2440111C (ko) |
CY (1) | CY1108845T1 (ko) |
CZ (1) | CZ302848B6 (ko) |
DE (1) | DE60229922D1 (ko) |
DK (1) | DK1372650T3 (ko) |
ES (1) | ES2318001T3 (ko) |
HK (1) | HK1061516A1 (ko) |
HU (1) | HUP0303621A3 (ko) |
IL (1) | IL157333A0 (ko) |
MX (1) | MXPA03008462A (ko) |
NO (1) | NO333106B1 (ko) |
NZ (1) | NZ541703A (ko) |
PT (1) | PT1372650E (ko) |
RU (1) | RU2330661C2 (ko) |
SI (1) | SI1372650T1 (ko) |
SK (1) | SK287334B6 (ko) |
TW (1) | TWI331525B (ko) |
WO (1) | WO2002074042A2 (ko) |
ZA (1) | ZA200306318B (ko) |
Families Citing this family (35)
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DE69734362T2 (de) * | 1996-12-03 | 2006-07-20 | Sloan-Kettering Institute For Cancer Research | Synthese von epothilonen, zwischenprodukte dazu, analoga und verwendungen davon |
US20020058286A1 (en) * | 1999-02-24 | 2002-05-16 | Danishefsky Samuel J. | Synthesis of epothilones, intermediates thereto and analogues thereof |
AU2001280120A1 (en) * | 2000-08-24 | 2002-03-04 | Chugai Seiyaku Kabushiki Kaisha | Cyclic peptide derivative |
ES2384789T3 (es) | 2001-03-14 | 2012-07-12 | Bristol-Myers Squibb Company | Combinación de un análogo de epotilona y agentes quimioterapéuticos para el tratamiento de enfermedades proliferativas |
US6727261B2 (en) * | 2001-12-27 | 2004-04-27 | Hoffman-La Roche Inc. | Pyrido[2,1-A]Isoquinoline derivatives |
DK1767535T3 (da) | 2002-08-23 | 2010-04-12 | Sloan Kettering Inst Cancer | Syntese af epothiloner, mellemprodukter deraf, analoge og deres anvendelse |
US7649006B2 (en) | 2002-08-23 | 2010-01-19 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto and analogues thereof |
US20040242566A1 (en) * | 2003-03-25 | 2004-12-02 | Syrrx, Inc. | Dipeptidyl peptidase inhibitors |
US7678909B1 (en) | 2003-08-13 | 2010-03-16 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
CN1867560A (zh) * | 2003-08-13 | 2006-11-22 | 武田药品工株式会社 | 4-嘧啶酮衍生物及其作为肽基肽酶抑制剂的用途 |
US7169926B1 (en) | 2003-08-13 | 2007-01-30 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
EP1699777B1 (en) * | 2003-09-08 | 2012-12-12 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
US20050065144A1 (en) * | 2003-09-08 | 2005-03-24 | Syrrx, Inc. | Dipeptidyl peptidase inhibitors |
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