NO333106B1 - Sammensetninger som omfatter et antidiar±middel og et epotilon eller et epotilonderivat, samt anvendelse derav - Google Patents
Sammensetninger som omfatter et antidiar±middel og et epotilon eller et epotilonderivat, samt anvendelse derav Download PDFInfo
- Publication number
- NO333106B1 NO333106B1 NO20034094A NO20034094A NO333106B1 NO 333106 B1 NO333106 B1 NO 333106B1 NO 20034094 A NO20034094 A NO 20034094A NO 20034094 A NO20034094 A NO 20034094A NO 333106 B1 NO333106 B1 NO 333106B1
- Authority
- NO
- Norway
- Prior art keywords
- epothilone
- hydrogen
- formula
- alkyl
- inhibitor
- Prior art date
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
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- A—HUMAN NECESSITIES
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- A61P13/10—Drugs for disorders of the urinary system of the bladder
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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Landscapes
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- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
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- Reproductive Health (AREA)
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- Pregnancy & Childbirth (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27715301P | 2001-03-19 | 2001-03-19 | |
| US27720701P | 2001-03-20 | 2001-03-20 | |
| PCT/EP2002/002977 WO2002074042A2 (en) | 2001-03-19 | 2002-03-18 | Combinations comprising an antidiarrheal agent and an epothilone or an epothilone derivative |
Publications (3)
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| NO20034094D0 NO20034094D0 (no) | 2003-09-15 |
| NO20034094L NO20034094L (no) | 2003-09-15 |
| NO333106B1 true NO333106B1 (no) | 2013-03-04 |
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| NO20034094A NO333106B1 (no) | 2001-03-19 | 2003-09-15 | Sammensetninger som omfatter et antidiar±middel og et epotilon eller et epotilonderivat, samt anvendelse derav |
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| US (1) | US7030147B2 (cs) |
| EP (1) | EP1372650B1 (cs) |
| JP (2) | JP2004519493A (cs) |
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| AU (1) | AU2002251067B2 (cs) |
| BR (1) | BR0208142A (cs) |
| CA (1) | CA2440111C (cs) |
| CY (1) | CY1108845T1 (cs) |
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| DK (1) | DK1372650T3 (cs) |
| ES (1) | ES2318001T3 (cs) |
| HU (1) | HUP0303621A3 (cs) |
| IL (1) | IL157333A0 (cs) |
| MX (1) | MXPA03008462A (cs) |
| NO (1) | NO333106B1 (cs) |
| NZ (1) | NZ541703A (cs) |
| PT (1) | PT1372650E (cs) |
| RU (1) | RU2330661C2 (cs) |
| SI (1) | SI1372650T1 (cs) |
| SK (1) | SK287334B6 (cs) |
| TW (1) | TWI331525B (cs) |
| WO (1) | WO2002074042A2 (cs) |
| ZA (1) | ZA200306318B (cs) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2273083C (en) * | 1996-12-03 | 2012-09-18 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto, analogues and uses thereof |
| US6204388B1 (en) | 1996-12-03 | 2001-03-20 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto and analogues thereof |
| US20020058286A1 (en) * | 1999-02-24 | 2002-05-16 | Danishefsky Samuel J. | Synthesis of epothilones, intermediates thereto and analogues thereof |
| EP1312612A4 (en) * | 2000-08-24 | 2004-09-22 | Chugai Pharmaceutical Co Ltd | CYCLIC PEPTIDE DERIVATIVE |
| CN1496256A (zh) | 2001-03-14 | 2004-05-12 | ����˹�ж�-����˹˹������˾ | 用于治疗增生性疾病的埃博霉素(epo thilone)类似物和化疗剂的组合 |
| US6727261B2 (en) * | 2001-12-27 | 2004-04-27 | Hoffman-La Roche Inc. | Pyrido[2,1-A]Isoquinoline derivatives |
| ATE450534T1 (de) | 2002-08-23 | 2009-12-15 | Sloan Kettering Inst Cancer | Synthese von epothilonen, zwischenprodukte davon, analoga und ihre verwendung |
| US6921769B2 (en) | 2002-08-23 | 2005-07-26 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto and analogues thereof |
| US7649006B2 (en) | 2002-08-23 | 2010-01-19 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto and analogues thereof |
| US20040242568A1 (en) * | 2003-03-25 | 2004-12-02 | Syrrx, Inc. | Dipeptidyl peptidase inhibitors |
| EP1625122A1 (en) | 2003-05-14 | 2006-02-15 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
| US7678909B1 (en) | 2003-08-13 | 2010-03-16 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
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| RU2253440C1 (ru) * | 2004-03-31 | 2005-06-10 | Открытое Акционерное Общество "Фаберлик" | Средство для устранения нарушений нейрогенной и эндокринной регуляции системы капиллярного кровотока |
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| JP5027137B2 (ja) * | 2005-09-14 | 2012-09-19 | 武田薬品工業株式会社 | ジペプチジルペプチダーゼ阻害剤の投与 |
| PL1931350T5 (pl) * | 2005-09-14 | 2021-11-15 | Takeda Pharmaceutical Company Limited | Podanie inhibitorów dipeptydylo-peptydazy |
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| SE9301831D0 (sv) * | 1993-05-28 | 1993-05-28 | Analytecon S A | Pharmaceutical compositions |
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| US5969145A (en) * | 1996-08-30 | 1999-10-19 | Novartis Ag | Process for the production of epothilones and intermediate products within the process |
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| PT1140944E (pt) * | 1998-12-22 | 2004-01-30 | Novartis Pharma Gmbh | Derivados de epotilona e sua utilizacao como agentes antitumorais |
| AU2001266583A1 (en) * | 2000-05-26 | 2001-12-11 | Kosan Biosciences, Inc. | Epothilone derivatives and methods for making and using the same |
| WO2003057217A1 (en) * | 2002-01-14 | 2003-07-17 | Novartis Ag | Combinations comprising epothilones and anti-metabolites |
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