NO333085B1 - Opploselig CRAM-1 polypeptid antistoff rettet mot CRAM-1 og som modulerer transendotelial migrering av leukocytter, samt anvendelse derav for fremstilling av medikamenter for inhibering av angiogenese i tumorer. - Google Patents

Opploselig CRAM-1 polypeptid antistoff rettet mot CRAM-1 og som modulerer transendotelial migrering av leukocytter, samt anvendelse derav for fremstilling av medikamenter for inhibering av angiogenese i tumorer.

Info

Publication number
NO333085B1
NO333085B1 NO20014417A NO20014417A NO333085B1 NO 333085 B1 NO333085 B1 NO 333085B1 NO 20014417 A NO20014417 A NO 20014417A NO 20014417 A NO20014417 A NO 20014417A NO 333085 B1 NO333085 B1 NO 333085B1
Authority
NO
Norway
Prior art keywords
cram
jam
cells
cell
endothelial
Prior art date
Application number
NO20014417A
Other languages
English (en)
Norwegian (no)
Other versions
NO20014417L (no
NO20014417D0 (no
Inventor
Beat Albert Imhof
Michel Aurrand-Lions
Original Assignee
Merck Serono Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Serono Sa filed Critical Merck Serono Sa
Publication of NO20014417D0 publication Critical patent/NO20014417D0/no
Publication of NO20014417L publication Critical patent/NO20014417L/no
Publication of NO333085B1 publication Critical patent/NO333085B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20014417A 1999-03-11 2001-09-11 Opploselig CRAM-1 polypeptid antistoff rettet mot CRAM-1 og som modulerer transendotelial migrering av leukocytter, samt anvendelse derav for fremstilling av medikamenter for inhibering av angiogenese i tumorer. NO333085B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99200746 1999-03-11
PCT/EP2000/002219 WO2000053749A2 (en) 1999-03-11 2000-03-13 Vascular adhesion molecules and modulation of their function

Publications (3)

Publication Number Publication Date
NO20014417D0 NO20014417D0 (no) 2001-09-11
NO20014417L NO20014417L (no) 2001-11-12
NO333085B1 true NO333085B1 (no) 2013-02-25

Family

ID=8239973

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20014417A NO333085B1 (no) 1999-03-11 2001-09-11 Opploselig CRAM-1 polypeptid antistoff rettet mot CRAM-1 og som modulerer transendotelial migrering av leukocytter, samt anvendelse derav for fremstilling av medikamenter for inhibering av angiogenese i tumorer.

Country Status (23)

Country Link
US (3) US7393651B2 (et)
EP (2) EP2292761A1 (et)
JP (2) JP4836329B2 (et)
CN (2) CN1637019A (et)
AT (1) ATE500328T1 (et)
AU (1) AU782139B2 (et)
BR (1) BR0008915A (et)
CA (1) CA2362896C (et)
CZ (1) CZ303128B6 (et)
DE (1) DE60045681D1 (et)
EE (1) EE05497B1 (et)
ES (1) ES2361905T3 (et)
HK (1) HK1044169A1 (et)
HU (1) HU229376B1 (et)
IL (1) IL145310A0 (et)
IS (1) IS2819B (et)
MX (1) MXPA01009110A (et)
NO (1) NO333085B1 (et)
NZ (1) NZ514091A (et)
PL (1) PL207994B1 (et)
RU (1) RU2244748C2 (et)
WO (1) WO2000053749A2 (et)
ZA (1) ZA200107283B (et)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8007798B2 (en) 1997-11-21 2011-08-30 Genentech, Inc. Treatment of complement-associated disorders
US8088386B2 (en) 1998-03-20 2012-01-03 Genentech, Inc. Treatment of complement-associated disorders
IL145310A0 (en) * 1999-03-11 2003-01-12 Rmf Dictagene Sa Vascular adhesion molecules and modulation of their function
GB0100750D0 (en) * 2001-01-11 2001-02-21 Inpharmatica Ltd Novel proteins
WO2003006673A2 (en) * 2001-07-11 2003-01-23 Texas Biotechnology Corporation A nucleic acid encoding a human junctional adhesion protein (jam3)
US7642341B2 (en) 2003-12-18 2010-01-05 Merck Serono S.A. Angiogenesis inhibiting molecules, their selection, production and their use in the treatment of cancer
EP1533617A1 (en) * 2003-11-19 2005-05-25 RMF Dictagene S.A. Angiogenesis inhibiting molecules, their selection, production and their use in the treatment and diagnosis of cancer
KR20170002684A (ko) 2005-11-04 2017-01-06 제넨테크, 인크. 안질환 치료를 위한 보체 경로 억제제의 용도
RU2464030C2 (ru) * 2006-05-26 2012-10-20 Регадо Байосайенсиз, Инк. Введение противосвертывающей системы reg1
AU2007301599B2 (en) 2006-09-28 2013-01-10 Merck Serono S.A. Junctional Adhesion Molecule-C (JAM-C) binding compounds and methods of their use
PE20121034A1 (es) 2006-11-02 2012-08-25 Genentech Inc Anticuerpos anti-factor d humanizados
FR2909092B1 (fr) * 2006-11-24 2012-10-19 Pf Medicament Nouveaux anticorps anti-proliferation
AR066660A1 (es) 2007-05-23 2009-09-02 Genentech Inc Prevencion y tratamiento de condiciones del ojo asociadas con su complemento
DK2190991T3 (da) * 2007-08-06 2020-02-10 Noxxon Pharma Ag SDF-1-Bindende nucleinsyrer og anvendelsen deraf
CR20170001A (es) 2008-04-28 2017-08-10 Genentech Inc Anticuerpos anti factor d humanizados
CN107318267B (zh) 2013-08-12 2021-08-17 豪夫迈·罗氏有限公司 用于治疗补体相关的病症的组合物和方法
EA201692109A1 (ru) 2014-05-01 2017-03-31 Дженентек, Инк. Варианты антител к фактору d и их применение
EP3368090A1 (en) 2015-10-30 2018-09-05 H. Hoffnabb-La Roche Ag Anti-factor d antibody variant conjugates and uses thereof
CN108289951A (zh) 2015-10-30 2018-07-17 豪夫迈·罗氏有限公司 抗-因子d抗体和缀合物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000053753A2 (en) * 1999-03-08 2000-09-14 Genentech, Inc. Promotion or inhibition of angiogenesis and cardiovascularization
US20030170864A1 (en) * 2000-05-30 2003-09-11 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
SE9604470D0 (sv) * 1996-12-04 1996-12-04 Tamas Bartfai Konsulting Ab Transmembrane component of tight junction
EP0973892A2 (en) * 1997-03-14 2000-01-26 Human Genome Sciences, Inc. 28 human secreted proteins
CA2283631A1 (en) * 1997-03-21 1998-10-01 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
CA2296809A1 (en) 1997-08-01 1999-02-11 Genset 5' ests for secreted proteins identified from brain tissues
US20030054400A1 (en) * 1997-09-17 2003-03-20 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP1002864A1 (en) * 1998-11-10 2000-05-24 Universita' degli studi di Bologna HIgR and related V domain for the manufacture of a medicament for preventing or treating HSV-1, HSV-2 and BHV infections
EP1141285A2 (en) * 1998-12-16 2001-10-10 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
IL145310A0 (en) * 1999-03-11 2003-01-12 Rmf Dictagene Sa Vascular adhesion molecules and modulation of their function
EP1533617A1 (en) 2003-11-19 2005-05-25 RMF Dictagene S.A. Angiogenesis inhibiting molecules, their selection, production and their use in the treatment and diagnosis of cancer
US7642341B2 (en) * 2003-12-18 2010-01-05 Merck Serono S.A. Angiogenesis inhibiting molecules, their selection, production and their use in the treatment of cancer

Also Published As

Publication number Publication date
DE60045681D1 (de) 2011-04-14
HU229376B1 (en) 2013-11-28
CA2362896A1 (en) 2000-09-14
JP2002537837A (ja) 2002-11-12
US20080274970A1 (en) 2008-11-06
IS6072A (is) 2001-09-10
RU2244748C2 (ru) 2005-01-20
EP2292761A1 (en) 2011-03-09
HUP0200606A2 (en) 2002-06-29
IS2819B (is) 2012-12-15
CZ303128B6 (cs) 2012-04-18
CN1637019A (zh) 2005-07-13
MXPA01009110A (es) 2002-08-20
JP2010233572A (ja) 2010-10-21
BR0008915A (pt) 2002-04-09
AU4105100A (en) 2000-09-28
IL145310A0 (en) 2003-01-12
ZA200107283B (en) 2002-12-24
HK1044169A1 (en) 2002-10-11
EE200100472A (et) 2002-12-16
CZ20013267A3 (cs) 2002-02-13
NZ514091A (en) 2004-01-30
EP1163337A2 (en) 2001-12-19
PL350417A1 (en) 2002-12-16
PL207994B1 (pl) 2011-02-28
EP1163337B1 (en) 2011-03-02
ES2361905T3 (es) 2011-06-24
JP4836329B2 (ja) 2011-12-14
WO2000053749A3 (en) 2000-12-14
US7393651B2 (en) 2008-07-01
US7670826B2 (en) 2010-03-02
US20100267649A1 (en) 2010-10-21
NO20014417L (no) 2001-11-12
CN1355843A (zh) 2002-06-26
NO20014417D0 (no) 2001-09-11
WO2000053749A2 (en) 2000-09-14
US20050266426A1 (en) 2005-12-01
AU782139B2 (en) 2005-07-07
HUP0200606A3 (en) 2004-11-29
EE05497B1 (et) 2011-12-15
US8143056B2 (en) 2012-03-27
CN100469878C (zh) 2009-03-18
ATE500328T1 (de) 2011-03-15
CA2362896C (en) 2012-07-31

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