NO327141B1 - Forbindelsen 9-cis retinsyre for anvendelse ved behandling av eksem samt anvendelse av denne for fremstilling av medikament for behandling av eksem. - Google Patents
Forbindelsen 9-cis retinsyre for anvendelse ved behandling av eksem samt anvendelse av denne for fremstilling av medikament for behandling av eksem. Download PDFInfo
- Publication number
- NO327141B1 NO327141B1 NO20000870A NO20000870A NO327141B1 NO 327141 B1 NO327141 B1 NO 327141B1 NO 20000870 A NO20000870 A NO 20000870A NO 20000870 A NO20000870 A NO 20000870A NO 327141 B1 NO327141 B1 NO 327141B1
- Authority
- NO
- Norway
- Prior art keywords
- eczema
- retinoic acid
- use according
- pharmaceutically acceptable
- treatment
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97114651A EP0908179A1 (fr) | 1997-08-23 | 1997-08-23 | Traitement de troubles immunitaires induits par les cellules |
| PCT/EP1998/005236 WO1999009969A1 (fr) | 1997-08-23 | 1998-08-18 | Traitement des maladies du systeme immunitaire propagees par les cellules |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20000870L NO20000870L (no) | 2000-02-22 |
| NO20000870D0 NO20000870D0 (no) | 2000-02-22 |
| NO327141B1 true NO327141B1 (no) | 2009-05-04 |
Family
ID=8227266
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20000870A NO327141B1 (no) | 1997-08-23 | 2000-02-22 | Forbindelsen 9-cis retinsyre for anvendelse ved behandling av eksem samt anvendelse av denne for fremstilling av medikament for behandling av eksem. |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US6589989B1 (fr) |
| EP (2) | EP0908179A1 (fr) |
| JP (1) | JP3522220B2 (fr) |
| KR (1) | KR100596260B1 (fr) |
| CN (1) | CN1136845C (fr) |
| AT (1) | ATE259224T1 (fr) |
| AU (1) | AU739440B2 (fr) |
| BR (1) | BRPI9811989B8 (fr) |
| CA (1) | CA2301907C (fr) |
| DE (1) | DE69821624T2 (fr) |
| DK (1) | DK1007020T3 (fr) |
| ES (1) | ES2214729T3 (fr) |
| NO (1) | NO327141B1 (fr) |
| NZ (1) | NZ502812A (fr) |
| PT (1) | PT1007020E (fr) |
| RU (1) | RU2238083C2 (fr) |
| TR (1) | TR200000488T2 (fr) |
| WO (1) | WO1999009969A1 (fr) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8541469B2 (en) * | 1997-08-23 | 2013-09-24 | Glaxo Group Limited | Treatment of cell-mediated immune diseases |
| US20020031539A1 (en) * | 2000-08-30 | 2002-03-14 | The Brigham And Women's Hospital, Inc. | Oxidized forms of retinoic acid as ligands for peroxisome proliferator activated receptor gamma |
| DE10255861A1 (de) * | 2002-11-29 | 2004-06-17 | Axxima Pharmaceuticals Ag | Gegen Hepatitis C-Virusinfektionen nützliche Verbindungen und Substanzen |
| FR2834216B1 (fr) * | 2001-12-27 | 2004-04-30 | Pharmascience Lab | Composition cosmetique ou pharmaceutique comprenant au moins une oxazoline pour inhiber la migration des cellules de langerhans, et ses utilisations |
| JP2004020220A (ja) * | 2002-06-12 | 2004-01-22 | Pioneer Electronic Corp | 通信システム及び方法、通信端末装置、通信センタ装置、並びにコンピュータプログラム |
| TW579640B (en) * | 2002-10-23 | 2004-03-11 | Veutron Corp | Light gathering device of scanner |
| EP1527774A1 (fr) | 2003-11-03 | 2005-05-04 | Basilea Pharmaceutica AG | Formulations nouvelle pour retinoides contenant capsules de gélatine molle |
| AU2004222279B2 (en) | 2003-03-14 | 2010-01-21 | University Of Washington | Retinoid replacements and opsin agonists and methods for the use thereof |
| KR100743278B1 (ko) | 2003-04-11 | 2007-07-26 | 에프. 호프만-라 로슈 아게 | 9-시스 레티노산의 제조 방법 |
| US7122751B1 (en) * | 2004-01-16 | 2006-10-17 | Cobalt Flux | Switch apparatus |
| CN1921843A (zh) * | 2004-01-23 | 2007-02-28 | 独立行政法人科学技术振兴机构 | 含视黄酸的糖尿病治疗药 |
| AU2012216808B2 (en) * | 2004-06-18 | 2015-04-30 | University Of Washington | Retinal derivatives and methods for the use thereof for the treatment of visual disorders |
| AU2015207903B2 (en) * | 2004-06-18 | 2017-08-17 | University Of Washington | Retinal derivatives and methods for the use thereof for the treatment of visual disorders |
| SI2397133T1 (sl) * | 2004-06-18 | 2017-12-29 | University of Washington Intellectual Property and Technology Transfer | Retinalni derivati in metode za njihovo uporabo pri zdravljenju motenj vida |
| JP5042839B2 (ja) | 2005-09-09 | 2012-10-03 | 有限会社ケムフィズ | 腸疾患の予防及び／又は治療のための医薬 |
| US8324270B2 (en) | 2008-02-11 | 2012-12-04 | University Of Washington | Methods for the treatment and prevention of age-related retinal dysfunction |
| US8580278B2 (en) * | 2009-06-03 | 2013-11-12 | Trustees Of Dartmouth College | Nutraceutical composition and methods for preventing or treating multiple sclerosis |
| JP5663025B2 (ja) | 2009-09-15 | 2015-02-04 | キューエルティー インコーポレイテッド | ９−ｃｉｓ−レチニルエステルを脂質ビヒクル中に含む医薬製剤 |
| US8771693B2 (en) | 2009-10-27 | 2014-07-08 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for the generation and use of conformation-specific antibodies |
| WO2011132084A2 (fr) | 2010-04-19 | 2011-10-27 | Qlt Inc. | Régime et procédé thérapeutique pour le traitement ou l'amélioration de troubles de la vue associés à une carence en rétinoïdes endogènes |
| WO2012125724A1 (fr) | 2011-03-14 | 2012-09-20 | Beth Israel Deaconess Medical Center | Méthodes et compositions pour le traitement de troubles prolifératifs |
| WO2012149334A2 (fr) | 2011-04-27 | 2012-11-01 | Beth Israel Deaconess Medical Center, Inc. | Procédés et compositions pour préparer et utiliser des anticorps spécifiques à une conformation |
| CN102247348A (zh) * | 2011-05-23 | 2011-11-23 | 天津拓飞生物科技有限公司 | 9-顺式维甲酸在制备治疗糖尿病皮肤溃疡的药物中的应用 |
| US9439884B2 (en) | 2011-05-26 | 2016-09-13 | Beth Israel Deaconess Medical Center, Inc. | Methods for the treatment of immune disorders |
| WO2013009945A1 (fr) | 2011-07-12 | 2013-01-17 | The Brigham And Women's Hospital, Inc. | Compositions de psa contenant des lipides, procédés d'isolement et procédés pour les utiliser |
| CA2865935C (fr) | 2012-03-01 | 2021-12-14 | Qlt Inc. | Schemas et procede therapeutiques utilises pour ameliorer la fonction visuelle dans les troubles de la vue associes a une carence en retinoides endogenes |
| US9730941B2 (en) | 2012-06-07 | 2017-08-15 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for the inhibition of Pin1 |
| US9221854B2 (en) | 2012-08-17 | 2015-12-29 | Basf Se | Isomerization of olefinic compounds |
| JP6461792B2 (ja) | 2012-08-17 | 2019-01-30 | ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ | オレフィン化合物の異性化 |
| US20150202172A1 (en) * | 2014-01-22 | 2015-07-23 | Glaxo Group Limited | Novel method of use |
| US10351914B2 (en) | 2014-07-17 | 2019-07-16 | Beth Israel Deaconess Medical Center, Inc. | Biomarkers for Pin1-associated disorders |
| WO2016011268A1 (fr) | 2014-07-17 | 2016-01-21 | Beth Israel Deaconess Medical Center, Inc. | Acide tout-trans-rétinoïque (atra) pour moduler l'activité et la stabilité de pin1 |
| US10548864B2 (en) | 2015-03-12 | 2020-02-04 | Beth Israel Deaconess Medical Center, Inc. | Enhanced ATRA-related compounds for the treatment of proliferative diseases, autoimmune diseases, and addiction conditions |
| CA2997211A1 (fr) | 2015-08-19 | 2017-02-23 | President And Fellows Of Harvard College | Compositions de psa lipides et procedes associes |
| WO2018014012A1 (fr) | 2016-07-15 | 2018-01-18 | President And Fellows Of Harvard College | Compositions de glycolipide et procédés d'utilisation |
| CN113499335B (zh) * | 2021-07-13 | 2023-06-20 | 中国人民解放军军事科学院军事医学研究院 | 一种靶向自噬融合治疗神经退行性疾病的药物 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5525635A (en) * | 1986-02-04 | 1996-06-11 | Moberg; Sven | Pharmaceutical compositions containing propylene glycol and/or polyethylene glycol and urea as active main components and use thereof |
| US5093360A (en) * | 1989-04-07 | 1992-03-03 | Yu Ruey J | Retinal, derivatives and their therapeutic use |
| US5057501A (en) * | 1990-03-13 | 1991-10-15 | Dermatologic Research Corporation | Methods for treatment of papulosquamous and eczematous diseases |
| US5932622A (en) * | 1991-12-18 | 1999-08-03 | The Salk Institute For Biological Studies | Method for in vivo modulation of non-malignant skin-related processes with 9-cis-retinoic acid |
| KR100274101B1 (ko) | 1992-01-22 | 2000-12-15 | 프리돌린 클라우스너, 롤란드 비. 보레르 | 9-시스 레틴산을 함유하는 약제학적 조성물 |
| US5750570A (en) * | 1992-03-31 | 1998-05-12 | The Regents Of The University Of Michigan | Method of treatment of hyperpigmentation in black skin with retinoic acid and method of lightening black skin with retinoic acid |
| CA2093577C (fr) | 1992-05-07 | 2006-01-03 | Michael Klaus | Retinoides s-heterocyclique alkyl ou alkoxy substitues |
| TW272187B (fr) * | 1992-05-20 | 1996-03-11 | Hoffmann La Roche | |
| WO1994022818A1 (fr) * | 1993-04-05 | 1994-10-13 | Pfizer Inc. | Procede de preparation d'acide 9-cis retinoique |
| US5457129A (en) * | 1993-05-17 | 1995-10-10 | Research Development Foundation | Inhibition of nitric oxide production by retinoic acid |
| FR2717686B1 (fr) * | 1994-03-22 | 1996-06-28 | Fabre Pierre Cosmetique | Composition dermo-cosmétologique et procédé de préparation. |
| DE4415204A1 (de) * | 1994-04-30 | 1995-11-02 | Carl Heinrich Dr Weischer | Neue Retinol (Vitamin A) -Derivate, deren Herstellung und Verwendung als Arzneimittel und Kosmetika |
| FR2728790B1 (fr) * | 1994-12-29 | 1997-01-24 | Cird Galderma | Composition modulant l'apoptose comprenant du methonial ou tout facteur influencant le taux intracellulaire de methonial |
| US6083977A (en) * | 1994-12-30 | 2000-07-04 | Ligand Pharmaceuticals Incorporated | Trienoic retinoid compounds and methods |
| US5837728A (en) * | 1995-01-27 | 1998-11-17 | Molecular Design International | 9-cis retinoic acid esters and amides and uses thereof |
| FR2735367B1 (fr) * | 1995-06-19 | 1997-07-18 | Cird Galderma | Utilisation de ligands specifiques des recepteurs rxrs |
| FR2752734B1 (fr) * | 1996-09-02 | 1998-11-06 | Cird Galderma | Utilisation de retinoides pour la preparation d'un medicament destine a traiter les affections liees a une surexpression de vegf |
| US5994081A (en) * | 1998-04-27 | 1999-11-30 | Incyte Pharamaceuticals, Inc. | Human keratins |
| US20030105031A1 (en) * | 2001-11-06 | 2003-06-05 | Rosenbloom Richard A. | Methods for the treatment of skin disorders |
-
1997
- 1997-08-23 EP EP97114651A patent/EP0908179A1/fr not_active Withdrawn
-
1998
- 1998-08-18 TR TR2000/00488T patent/TR200000488T2/xx unknown
- 1998-08-18 WO PCT/EP1998/005236 patent/WO1999009969A1/fr not_active Application Discontinuation
- 1998-08-18 US US09/485,943 patent/US6589989B1/en not_active Expired - Lifetime
- 1998-08-18 CA CA002301907A patent/CA2301907C/fr not_active Expired - Lifetime
- 1998-08-18 KR KR1020007001813A patent/KR100596260B1/ko active IP Right Grant
- 1998-08-18 CN CNB98808743XA patent/CN1136845C/zh not_active Expired - Lifetime
- 1998-08-18 RU RU2000107124/14A patent/RU2238083C2/ru active
- 1998-08-18 JP JP2000507359A patent/JP3522220B2/ja not_active Expired - Lifetime
- 1998-08-18 DE DE69821624T patent/DE69821624T2/de not_active Expired - Lifetime
- 1998-08-18 ES ES98947437T patent/ES2214729T3/es not_active Expired - Lifetime
- 1998-08-18 DK DK98947437T patent/DK1007020T3/da active
- 1998-08-18 PT PT98947437T patent/PT1007020E/pt unknown
- 1998-08-18 BR BRPI9811989A patent/BRPI9811989B8/pt not_active IP Right Cessation
- 1998-08-18 NZ NZ502812A patent/NZ502812A/en not_active IP Right Cessation
- 1998-08-18 AT AT98947437T patent/ATE259224T1/de active
- 1998-08-18 AU AU94356/98A patent/AU739440B2/en not_active Expired
- 1998-08-18 EP EP98947437A patent/EP1007020B1/fr not_active Expired - Lifetime
-
2000
- 2000-02-22 NO NO20000870A patent/NO327141B1/no not_active IP Right Cessation
-
2003
- 2003-06-11 US US10/459,273 patent/US20040039056A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20040039056A1 (en) | 2004-02-26 |
| PT1007020E (pt) | 2004-05-31 |
| ATE259224T1 (de) | 2004-02-15 |
| CA2301907A1 (fr) | 1999-03-04 |
| AU9435698A (en) | 1999-03-16 |
| US6589989B1 (en) | 2003-07-08 |
| EP0908179A1 (fr) | 1999-04-14 |
| DE69821624T2 (de) | 2004-09-23 |
| RU2238083C2 (ru) | 2004-10-20 |
| BR9811989A (pt) | 2000-09-05 |
| NZ502812A (en) | 2002-05-31 |
| EP1007020A1 (fr) | 2000-06-14 |
| JP2003526595A (ja) | 2003-09-09 |
| NO20000870L (no) | 2000-02-22 |
| JP3522220B2 (ja) | 2004-04-26 |
| BRPI9811989B1 (pt) | 2015-12-15 |
| ES2214729T3 (es) | 2004-09-16 |
| WO1999009969A1 (fr) | 1999-03-04 |
| CN1136845C (zh) | 2004-02-04 |
| BRPI9811989B8 (pt) | 2021-05-25 |
| CN1268886A (zh) | 2000-10-04 |
| TR200000488T2 (tr) | 2000-07-21 |
| KR100596260B1 (ko) | 2006-07-03 |
| AU739440B2 (en) | 2001-10-11 |
| CA2301907C (fr) | 2009-02-10 |
| DE69821624D1 (de) | 2004-03-18 |
| KR20010023186A (ko) | 2001-03-26 |
| DK1007020T3 (da) | 2004-06-07 |
| NO20000870D0 (no) | 2000-02-22 |
| EP1007020B1 (fr) | 2004-02-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| CHAD | Change of the owner's name or address (par. 44 patent law, par. patentforskriften) |
Owner name: CLAXO GROUP LTD, GB |
|
| CREP | Change of representative |
Representative=s name: ZACCO NORWAY AS, POSTBOKS 2003 VIKA, 0125 OSLO |
|
| MK1K | Patent expired |