NO326996B1 - Anvendelse av trombininhibitor for fremstilling av et medikament for dialysebehandling. - Google Patents

Anvendelse av trombininhibitor for fremstilling av et medikament for dialysebehandling. Download PDF

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Publication number
NO326996B1
NO326996B1 NO20013301A NO20013301A NO326996B1 NO 326996 B1 NO326996 B1 NO 326996B1 NO 20013301 A NO20013301 A NO 20013301A NO 20013301 A NO20013301 A NO 20013301A NO 326996 B1 NO326996 B1 NO 326996B1
Authority
NO
Norway
Prior art keywords
dialysis
melagatran
molecular weight
low molecular
thrombin inhibitor
Prior art date
Application number
NO20013301A
Other languages
English (en)
Norwegian (no)
Other versions
NO20013301D0 (no
NO20013301L (no
Inventor
Gunnar Fager
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20013301D0 publication Critical patent/NO20013301D0/no
Publication of NO20013301L publication Critical patent/NO20013301L/no
Publication of NO326996B1 publication Critical patent/NO326996B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654Dialysates therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/342Adding solutions to the blood, e.g. substitution solutions
    • A61M1/3424Substitution fluid path
    • A61M1/3427Substitution fluid path back through the membrane, e.g. by inverted trans-membrane pressure [TMP]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3672Means preventing coagulation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Peptides Or Proteins (AREA)
NO20013301A 1999-01-11 2001-07-03 Anvendelse av trombininhibitor for fremstilling av et medikament for dialysebehandling. NO326996B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9900043A SE9900043D0 (sv) 1999-01-11 1999-01-11 New use
PCT/SE2000/000030 WO2000041715A1 (en) 1999-01-11 2000-01-11 New dialysis method

Publications (3)

Publication Number Publication Date
NO20013301D0 NO20013301D0 (no) 2001-07-03
NO20013301L NO20013301L (no) 2001-07-03
NO326996B1 true NO326996B1 (no) 2009-03-30

Family

ID=20414050

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20013301A NO326996B1 (no) 1999-01-11 2001-07-03 Anvendelse av trombininhibitor for fremstilling av et medikament for dialysebehandling.

Country Status (19)

Country Link
US (4) US20030042202A1 (ko)
EP (1) EP1144000B1 (ko)
JP (1) JP4054533B2 (ko)
KR (1) KR100840452B1 (ko)
CN (1) CN100387296C (ko)
AT (1) ATE316384T1 (ko)
AU (1) AU763185B2 (ko)
BR (1) BR0007448A (ko)
CA (1) CA2356440A1 (ko)
CY (1) CY1107461T1 (ko)
DE (1) DE60025698T2 (ko)
DK (1) DK1144000T3 (ko)
ES (1) ES2255968T3 (ko)
IL (1) IL143824A0 (ko)
NO (1) NO326996B1 (ko)
NZ (1) NZ512712A (ko)
SE (1) SE9900043D0 (ko)
WO (1) WO2000041715A1 (ko)
ZA (1) ZA200105274B (ko)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1396270E (pt) 2002-09-09 2006-08-31 Trigen Ltd Processo para a preparacao de compostos uteisncomo intermidiarios.
US7371729B2 (en) 2002-09-09 2008-05-13 Trigen Limited Boronic acid salts useful in parenteral formulations
US7235589B2 (en) * 2004-09-21 2007-06-26 Bio Numerik Pharmaceuticals, Inc. Method of treating patients undergoing kidney dialysis
MX338460B (es) 2005-12-21 2016-04-15 Meso Scale Technologies Llc Aparatos, metodos y reactivos de ensayo.
CN105115949B (zh) * 2005-12-21 2018-06-22 梅索斯卡莱科技公司 分析装置、方法和试剂
US20070155672A1 (en) * 2006-01-05 2007-07-05 Markus Voges Sterilized peritoneal dialysis solutions containing heparin
EP3165245B1 (en) * 2011-08-02 2019-02-20 Medtronic, Inc. Hemodialysis system having a flow path with a controlled compliant volume
US10010663B2 (en) 2013-02-01 2018-07-03 Medtronic, Inc. Fluid circuit for delivery of renal replacement therapies
US9623164B2 (en) 2013-02-01 2017-04-18 Medtronic, Inc. Systems and methods for multifunctional volumetric fluid control
US10850016B2 (en) 2013-02-01 2020-12-01 Medtronic, Inc. Modular fluid therapy system having jumpered flow paths and systems and methods for cleaning and disinfection
US10098993B2 (en) 2014-12-10 2018-10-16 Medtronic, Inc. Sensing and storage system for fluid balance
US9713665B2 (en) 2014-12-10 2017-07-25 Medtronic, Inc. Degassing system for dialysis
US10874787B2 (en) 2014-12-10 2020-12-29 Medtronic, Inc. Degassing system for dialysis
US11278654B2 (en) 2017-12-07 2022-03-22 Medtronic, Inc. Pneumatic manifold for a dialysis system
US11033667B2 (en) 2018-02-02 2021-06-15 Medtronic, Inc. Sorbent manifold for a dialysis system
US11110215B2 (en) 2018-02-23 2021-09-07 Medtronic, Inc. Degasser and vent manifolds for dialysis

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU178398B (en) * 1979-06-12 1982-04-28 Gyogyszerkutato Intezet Process for producing new agmatine derivatives of activity against haemagglutination
US4489535A (en) * 1980-10-02 1984-12-25 Veltman Preston Leonard Materials and method for preparing dialysis solutions containing bicarbonate ions
GR870129B (en) * 1987-01-27 1987-02-04 Giatzidis Ippokratis Stable bicarbonate - glycylglycine dialysate for hemodialysis and peritoneal dialysis
SE9103612D0 (sv) * 1991-12-04 1991-12-04 Astra Ab New peptide derivatives
US5549674A (en) * 1992-03-02 1996-08-27 The Regents Of The University Of Michigan Methods and compositions of a bioartificial kidney suitable for use in vivo or ex vivo
SE9301916D0 (sv) * 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
DE4321444A1 (de) * 1993-06-28 1995-01-05 Bernd Prof Dr Clement Pharmazeutische Zubereitung
US5380299A (en) * 1993-08-30 1995-01-10 Med Institute, Inc. Thrombolytic treated intravascular medical device
US5707966A (en) * 1994-03-04 1998-01-13 Eli Lilly And Company Antithrombotic agents
US5705487A (en) * 1994-03-04 1998-01-06 Eli Lilly And Company Antithrombotic agents
DE4443390A1 (de) * 1994-12-06 1996-06-13 Basf Ag Neue dipeptidische p-Amidinobenzylamide mit N-terminalen Sulfonyl- bzw. Aminosulfonylresten
CA2210989A1 (en) * 1995-02-10 1996-08-15 Basf Aktiengesellschaft Thrombin inhibitors
US5710130A (en) * 1995-02-27 1998-01-20 Eli Lilly And Company Antithrombotic agents
SE9600216D0 (sv) * 1996-01-18 1996-01-18 Hans Arne Hansson Styrning av läkningsprocesser
EP1007544A1 (en) * 1996-02-13 2000-06-14 Akzo Nobel N.V. Serine protease inhibitors
EP0884325A1 (en) * 1997-04-24 1998-12-16 Akzo Nobel N.V. Thrombin inhibitors containing a peptidyl heterocycle
AU7470098A (en) * 1997-04-30 1998-11-24 Eli Lilly And Company Antithrombotic agents
EP1019047B1 (en) * 1997-05-01 2003-11-05 Eli Lilly And Company Antithrombotic agents
RU2183642C2 (ru) * 1997-05-02 2002-06-20 Акцо Нобель Н.В. Ингибиторы сериновых протеаз

Also Published As

Publication number Publication date
US20080004225A1 (en) 2008-01-03
JP2002534217A (ja) 2002-10-15
ES2255968T3 (es) 2006-07-16
EP1144000B1 (en) 2006-01-25
ATE316384T1 (de) 2006-02-15
EP1144000A1 (en) 2001-10-17
SE9900043D0 (sv) 1999-01-11
DE60025698D1 (de) 2006-04-13
NO20013301D0 (no) 2001-07-03
JP4054533B2 (ja) 2008-02-27
NO20013301L (no) 2001-07-03
CN1354673A (zh) 2002-06-19
CN100387296C (zh) 2008-05-14
CA2356440A1 (en) 2000-07-20
AU763185B2 (en) 2003-07-17
KR20010093250A (ko) 2001-10-27
DE60025698T2 (de) 2006-10-19
US20030042202A1 (en) 2003-03-06
US20090192137A1 (en) 2009-07-30
KR100840452B1 (ko) 2008-06-20
AU2140900A (en) 2000-08-01
ZA200105274B (en) 2002-09-26
IL143824A0 (en) 2002-04-21
WO2000041715A1 (en) 2000-07-20
US20050153904A1 (en) 2005-07-14
BR0007448A (pt) 2001-10-16
NZ512712A (en) 2004-09-24
CY1107461T1 (el) 2012-12-19
DK1144000T3 (da) 2006-05-08

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