NO324117B1 - Anvendelse av et kompleks omfattende IGF-I/IGFBP-3 til a fremstille et legemiddel til a behandle diabetes. - Google Patents

Anvendelse av et kompleks omfattende IGF-I/IGFBP-3 til a fremstille et legemiddel til a behandle diabetes. Download PDF

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Publication number
NO324117B1
NO324117B1 NO20015932A NO20015932A NO324117B1 NO 324117 B1 NO324117 B1 NO 324117B1 NO 20015932 A NO20015932 A NO 20015932A NO 20015932 A NO20015932 A NO 20015932A NO 324117 B1 NO324117 B1 NO 324117B1
Authority
NO
Norway
Prior art keywords
igf
igfbp
complex
insulin
type
Prior art date
Application number
NO20015932A
Other languages
English (en)
Norwegian (no)
Other versions
NO20015932L (no
NO20015932D0 (no
Inventor
Andreas Sommer
Original Assignee
Celtrix Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celtrix Pharma filed Critical Celtrix Pharma
Publication of NO20015932D0 publication Critical patent/NO20015932D0/no
Publication of NO20015932L publication Critical patent/NO20015932L/no
Publication of NO324117B1 publication Critical patent/NO324117B1/no

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/30Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
NO20015932A 1999-06-04 2001-12-04 Anvendelse av et kompleks omfattende IGF-I/IGFBP-3 til a fremstille et legemiddel til a behandle diabetes. NO324117B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/326,189 US6040292A (en) 1999-06-04 1999-06-04 Methods for treating diabetes
PCT/US2000/014163 WO2000074710A2 (en) 1999-06-04 2000-05-23 Methods for treating diabetes

Publications (3)

Publication Number Publication Date
NO20015932D0 NO20015932D0 (no) 2001-12-04
NO20015932L NO20015932L (no) 2002-01-31
NO324117B1 true NO324117B1 (no) 2007-08-27

Family

ID=23271175

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20015932A NO324117B1 (no) 1999-06-04 2001-12-04 Anvendelse av et kompleks omfattende IGF-I/IGFBP-3 til a fremstille et legemiddel til a behandle diabetes.

Country Status (16)

Country Link
US (1) US6040292A (de)
EP (1) EP1183042B1 (de)
JP (1) JP2003501397A (de)
KR (1) KR100694737B1 (de)
CN (1) CN1235637C (de)
AT (1) ATE271880T1 (de)
AU (1) AU780400B2 (de)
CA (1) CA2373281C (de)
DE (1) DE60012517T2 (de)
ES (1) ES2222208T3 (de)
HK (1) HK1044895A1 (de)
IL (1) IL146868A0 (de)
MX (1) MXPA01013384A (de)
NO (1) NO324117B1 (de)
WO (1) WO2000074710A2 (de)
ZA (1) ZA200110408B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6040292A (en) * 1999-06-04 2000-03-21 Celtrix Pharmaceuticals, Inc. Methods for treating diabetes
US20040022787A1 (en) 2000-07-03 2004-02-05 Robert Cohen Methods for treating an autoimmune disease using a soluble CTLA4 molecule and a DMARD or NSAID
DK1935427T3 (en) * 2000-07-03 2018-06-06 Bristol Myers Squibb Co APPLICATIONS OF SOLUBLE, MUTANT CTLA4 MOLECULES
AU9109001A (en) * 2000-09-19 2002-04-02 Bioexpertise Llc Method for use of IGF-binding protein for selective sensitization of target cells in vivo
US20040220190A1 (en) * 2002-07-29 2004-11-04 Cincotta Anthony H. Methods of treating metabolic syndrome using dopamine receptor agonists
US20040077679A1 (en) * 2002-07-29 2004-04-22 Cincotta Anthony H. Therapeutic treatment for the metabolic syndrome and type 2 diabetes
US9655865B2 (en) 2002-07-29 2017-05-23 Veroscience, Llc Therapeutic treatment for metabolic syndrome, type 2 diabetes, obesity, or prediabetes
US20080200453A1 (en) 2002-07-29 2008-08-21 Cincotta Anthony H Methods of treating metabolic syndrome using dopamine receptor agonists
US8821915B2 (en) 2002-08-09 2014-09-02 Veroscience, Llc Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders
US20040081678A1 (en) * 2002-08-09 2004-04-29 Anthony Cincotta Therapeutic process for the treatment of obesity and associated metabolic disorders
US8137994B2 (en) * 2004-03-25 2012-03-20 Veroscience Llc Methods of identifying responders to dopamine agonist therapy and treating metabolic conditions thereof
US20050215558A1 (en) * 2004-03-25 2005-09-29 Cincotta Anthony H Methods of identifying responders to dopamine agonist therapy
US8137993B2 (en) * 2004-03-25 2012-03-20 Veroscience Llc Methods of identifying responders to dopamine agonist therapy and treating metabolic conditions thereof
CN101128124A (zh) * 2004-12-30 2008-02-20 希尔氏宠物营养品公司 用于猫消费的组合物
JP5449134B2 (ja) * 2007-04-18 2014-03-19 プレーマクレ・アクチエボラーグ 未熟児合併症の治療及び/又は予防の方法と製品
EP2352514A4 (de) * 2008-10-29 2012-07-25 Univ Rockefeller Verfahren und kits zur krankheitsbehandlung durch verabreichung des einen insulinähnlichen wachstumsfaktor bindenden proteins 2
AR075998A1 (es) 2009-04-01 2011-05-11 Genentech Inc Tratamiento de trastornos resistentes a insulina.composicion farmaceutica. uso. kit
US9352025B2 (en) 2009-06-05 2016-05-31 Veroscience Llc Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders
US8575207B2 (en) 2010-08-16 2013-11-05 Allergan, Inc. Method of activating regulatory T cells with alpha-2B adrenergic receptor agonists

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5200509A (en) * 1987-04-06 1993-04-06 Celtrix Pharmaceuticals, Inc. Human somatomedin carrier protein subunits and process for producing them; recombinant DNA molecules, hosts, processes and human somatomedin carrier protein-like polypeptides
US4988675A (en) * 1988-02-05 1991-01-29 Ciba-Geigy Corporation Method for preventing secondary effects
GB8920381D0 (en) * 1989-09-08 1989-10-25 Greater Glasgow Health Board Treatment of insulin-resistant diabetes
SE9201573D0 (sv) * 1992-05-19 1992-05-19 Kabi Pharmacia Ab Use of igf-1
NZ255461A (en) * 1992-08-20 1996-12-20 Biotechnology & Biolog Science Specific binding molecules for insulin-like-growth-factor-1 (igf-1), antigens capable of generating them and their use in enhancing igf-1 activity
US5407913A (en) * 1992-12-03 1995-04-18 Celtrix Pharmaceuticals, Inc. Method and composition for systemic treatment of tissue injury
JPH08500123A (ja) * 1993-01-25 1996-01-09 ザ ベス イスラエル ホスピタル アソシエイション Igf−i感受性細胞のバリヤー特性の修飾方法,診断方法及びスクリーニング方法
US5563046A (en) * 1993-08-02 1996-10-08 Celtrix Pharmaceuticals, Inc. Fusion polypeptides and proteins
ATE190499T1 (de) * 1993-08-03 2000-04-15 Celtrix Pharma Methode zur behandlung von reproduktionserkrankungen
ES2241906T3 (es) * 1993-09-20 2005-11-01 Celtrix Pharmaceuticals, Inc. Tratamiento de trastornos inmunologicos y hematologicos con igfbp solo o asociado con igf.
JPH09509140A (ja) * 1993-11-15 1997-09-16 セルトリックス ファーマシューティカルズ,インコーポレイテッド 神経学的障害の治療方法
EP0732933B1 (de) * 1993-11-15 2002-10-09 Celtrix Pharmaceuticals, Inc. Verwendung von igf-1 und igfbp-3 zur herstellung eines arzneimittels zur behandlung von einer nierenerkrankung
JPH10512235A (ja) * 1994-07-20 1998-11-24 セルトリックス ファーマシューティカルズ,インコーポレイテッド 骨形成の促進および骨再造形の調節のためのigf/igfbp複合体
US5741776A (en) * 1995-05-22 1998-04-21 Genentech, Inc. Method of administration of IGF-I
US6436897B2 (en) * 1998-06-01 2002-08-20 Celtrix Pharmaceuticals, Inc. Pharmaceutical formulations for IGF/IGFBP
US6040292A (en) * 1999-06-04 2000-03-21 Celtrix Pharmaceuticals, Inc. Methods for treating diabetes

Also Published As

Publication number Publication date
AU5041100A (en) 2000-12-28
DE60012517D1 (de) 2004-09-02
AU780400B2 (en) 2005-03-17
CA2373281C (en) 2010-01-12
NO20015932L (no) 2002-01-31
IL146868A0 (en) 2002-08-14
WO2000074710A2 (en) 2000-12-14
ZA200110408B (en) 2003-03-19
CN1387440A (zh) 2002-12-25
MXPA01013384A (es) 2003-09-04
JP2003501397A (ja) 2003-01-14
US6040292A (en) 2000-03-21
HK1044895A1 (en) 2002-11-08
KR20020020723A (ko) 2002-03-15
ES2222208T3 (es) 2005-02-01
NO20015932D0 (no) 2001-12-04
KR100694737B1 (ko) 2007-03-14
WO2000074710A3 (en) 2001-06-28
EP1183042A2 (de) 2002-03-06
ATE271880T1 (de) 2004-08-15
CA2373281A1 (en) 2000-12-14
EP1183042B1 (de) 2004-07-28
CN1235637C (zh) 2006-01-11
DE60012517T2 (de) 2005-08-04

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