NO322359B1 - 1-(syklisk amino)-alkylsykloheksanforbindelser, farmasoytiske preparater derav og deres anvendelse som antikonvulsive midler - Google Patents
1-(syklisk amino)-alkylsykloheksanforbindelser, farmasoytiske preparater derav og deres anvendelse som antikonvulsive midler Download PDFInfo
- Publication number
- NO322359B1 NO322359B1 NO20022044A NO20022044A NO322359B1 NO 322359 B1 NO322359 B1 NO 322359B1 NO 20022044 A NO20022044 A NO 20022044A NO 20022044 A NO20022044 A NO 20022044A NO 322359 B1 NO322359 B1 NO 322359B1
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- Norway
- Prior art keywords
- compound
- cyclic amino
- compounds
- alkylcyclohexane
- amino
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/033—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP1999/008317 WO2001032640A1 (en) | 1999-11-01 | 1999-11-01 | 1-cyclic amino-alkylcyclohexane compounds, pharmaceutical compositions thereof, and their use as anticonvulsants |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20022044L NO20022044L (no) | 2002-04-30 |
| NO20022044D0 NO20022044D0 (no) | 2002-04-30 |
| NO322359B1 true NO322359B1 (no) | 2006-09-18 |
Family
ID=8167482
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20022044A NO322359B1 (no) | 1999-11-01 | 2002-04-30 | 1-(syklisk amino)-alkylsykloheksanforbindelser, farmasoytiske preparater derav og deres anvendelse som antikonvulsive midler |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1228052B1 (hu) |
| JP (1) | JP4043236B2 (hu) |
| KR (1) | KR100548600B1 (hu) |
| CN (1) | CN1264827C (hu) |
| AT (1) | ATE361284T1 (hu) |
| AU (1) | AU782760B2 (hu) |
| CA (1) | CA2389325C (hu) |
| CY (1) | CY1106672T1 (hu) |
| CZ (1) | CZ20021533A3 (hu) |
| DE (1) | DE69936004T2 (hu) |
| DK (1) | DK1228052T3 (hu) |
| EA (1) | EA005684B1 (hu) |
| ES (1) | ES2285870T3 (hu) |
| HK (1) | HK1049160B (hu) |
| HU (1) | HUP0203275A3 (hu) |
| IL (2) | IL149401A0 (hu) |
| MX (1) | MXPA02004368A (hu) |
| NO (1) | NO322359B1 (hu) |
| PL (1) | PL199587B1 (hu) |
| PT (1) | PT1228052E (hu) |
| SI (1) | SI1228052T1 (hu) |
| TW (1) | TWI242547B (hu) |
| UA (1) | UA72558C2 (hu) |
| WO (1) | WO2001032640A1 (hu) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7732162B2 (en) | 2003-05-05 | 2010-06-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases |
| WO2008055945A1 (en) | 2006-11-09 | 2008-05-15 | Probiodrug Ag | 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases |
| ATE554085T1 (de) | 2006-11-30 | 2012-05-15 | Probiodrug Ag | Neue inhibitoren von glutaminylcyclase |
| EP2117540A1 (en) | 2007-03-01 | 2009-11-18 | Probiodrug AG | New use of glutaminyl cyclase inhibitors |
| JP5667440B2 (ja) | 2007-04-18 | 2015-02-12 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤としてのチオ尿素誘導体 |
| SG178953A1 (en) | 2009-09-11 | 2012-04-27 | Probiodrug Ag | Heterocylcic derivatives as inhibitors of glutaminyl cyclase |
| US9181233B2 (en) | 2010-03-03 | 2015-11-10 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| AU2011226074B2 (en) | 2010-03-10 | 2015-01-22 | Vivoryon Therapeutics N.V. | Heterocyclic inhibitors of glutaminyl cyclase (QC, EC 2.3.2.5) |
| US8541596B2 (en) | 2010-04-21 | 2013-09-24 | Probiodrug Ag | Inhibitors |
| ES2570167T3 (es) | 2011-03-16 | 2016-05-17 | Probiodrug Ag | Derivados de benzimidazol como inhibidores de glutaminil ciclasa |
| CN104211663B (zh) * | 2014-08-11 | 2017-01-11 | 杭州偶联医药科技有限公司 | 一种(s)-n-甲氧基-甲基-2-(四氢吡咯基)丙酰胺及其制备方法和应用 |
| ES2812698T3 (es) | 2017-09-29 | 2021-03-18 | Probiodrug Ag | Inhibidores de glutaminil ciclasa |
| RU2714135C1 (ru) * | 2019-11-22 | 2020-02-12 | Федеральное государственное бюджетное учреждение науки "Институт токсикологии Федерального медико-биологического агентства" | Гидрохлорид (1-метилпиперидин-4-ил)-2-пропилпентаноата, обладающий холинолитической и противосудорожной активностью |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3097207A (en) * | 1958-03-06 | 1963-07-09 | Parke Davis & Co | 1-halophenyl and 1-alkoxyphenyl cyclohexylamines |
| TW593225B (en) * | 1997-06-30 | 2004-06-21 | Merz Pharma Gmbh & Co Kgaa | 1-amino-alkylcyclohexane NMDA receptor antagonists |
-
1999
- 1999-01-11 UA UA2002054475A patent/UA72558C2/uk unknown
- 1999-11-01 IL IL14940199A patent/IL149401A0/xx active IP Right Grant
- 1999-11-01 CZ CZ20021533A patent/CZ20021533A3/cs unknown
- 1999-11-01 CN CNB998169900A patent/CN1264827C/zh not_active Expired - Fee Related
- 1999-11-01 DE DE69936004T patent/DE69936004T2/de not_active Expired - Fee Related
- 1999-11-01 JP JP2001534791A patent/JP4043236B2/ja not_active Expired - Fee Related
- 1999-11-01 AU AU11585/00A patent/AU782760B2/en not_active Ceased
- 1999-11-01 CA CA002389325A patent/CA2389325C/en not_active Expired - Fee Related
- 1999-11-01 PL PL354519A patent/PL199587B1/pl not_active IP Right Cessation
- 1999-11-01 DK DK99974146T patent/DK1228052T3/da active
- 1999-11-01 MX MXPA02004368A patent/MXPA02004368A/es not_active IP Right Cessation
- 1999-11-01 ES ES99974146T patent/ES2285870T3/es not_active Expired - Lifetime
- 1999-11-01 EA EA200200522A patent/EA005684B1/ru not_active IP Right Cessation
- 1999-11-01 SI SI9930972T patent/SI1228052T1/sl unknown
- 1999-11-01 KR KR1020027005621A patent/KR100548600B1/ko not_active IP Right Cessation
- 1999-11-01 HU HU0203275A patent/HUP0203275A3/hu unknown
- 1999-11-01 AT AT99974146T patent/ATE361284T1/de not_active IP Right Cessation
- 1999-11-01 WO PCT/EP1999/008317 patent/WO2001032640A1/en active IP Right Grant
- 1999-11-01 EP EP99974146A patent/EP1228052B1/en not_active Expired - Lifetime
- 1999-11-01 PT PT99974146T patent/PT1228052E/pt unknown
- 1999-11-15 TW TW088119884A patent/TWI242547B/zh not_active IP Right Cessation
-
2002
- 2002-04-29 IL IL149401A patent/IL149401A/en not_active IP Right Cessation
- 2002-04-30 NO NO20022044A patent/NO322359B1/no not_active IP Right Cessation
-
2003
- 2003-02-18 HK HK03101158.3A patent/HK1049160B/zh not_active IP Right Cessation
-
2007
- 2007-06-21 CY CY20071100831T patent/CY1106672T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |