NO322210B1 - Sykliske substituerte sammensmeltede pyrrolokarbazoler og isoindoloner - Google Patents
Sykliske substituerte sammensmeltede pyrrolokarbazoler og isoindoloner Download PDFInfo
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- NO322210B1 NO322210B1 NO20013887A NO20013887A NO322210B1 NO 322210 B1 NO322210 B1 NO 322210B1 NO 20013887 A NO20013887 A NO 20013887A NO 20013887 A NO20013887 A NO 20013887A NO 322210 B1 NO322210 B1 NO 322210B1
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- XTBAPWCYTNCZTO-UHFFFAOYSA-N isoindol-1-one Chemical class C1=CC=C2C(=O)N=CC2=C1 XTBAPWCYTNCZTO-UHFFFAOYSA-N 0.000 title description 30
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Classifications
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Landscapes
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| PCT/US2000/003476 WO2000047583A1 (en) | 1999-02-12 | 2000-02-11 | Cyclic substituted fused pyrrolocarbazoles and isoindolones |
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| US6811992B1 (en) | 1998-05-14 | 2004-11-02 | Ya Fang Liu | Method for identifying MLK inhibitors for the treatment of neurological conditions |
| US6841567B1 (en) * | 1999-02-12 | 2005-01-11 | Cephalon, Inc. | Cyclic substituted fused pyrrolocarbazoles and isoindolones |
| US7122679B2 (en) * | 2000-05-09 | 2006-10-17 | Cephalon, Inc. | Multicyclic compounds and the use thereof |
| BR0113266A (pt) * | 2000-08-11 | 2005-01-04 | Cephalon Inc | Métodos para modular proteìnas quinase de linhagem múltipla e compostos protetores que modulam proteìnas quinase de linhagem múltipla |
| US6630500B2 (en) | 2000-08-25 | 2003-10-07 | Cephalon, Inc. | Selected fused pyrrolocarbazoles |
| US7018999B2 (en) | 2001-05-16 | 2006-03-28 | Cephalon, Inc. | Methods for the treatment and prevention of pain |
| DE10164581A1 (de) * | 2001-12-14 | 2003-06-26 | Gruenenthal Gmbh | Substituierte Aminoalkohole |
| TWI329105B (en) | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
| ES2421139T3 (es) | 2003-07-30 | 2013-08-29 | Rigel Pharmaceuticals, Inc. | Compuestos de 2,4-pirimidindiamina para su uso en el tratamiento o la prevención de enfermedades autoinmunitarias |
| US7241779B2 (en) | 2003-12-23 | 2007-07-10 | Cephalon, Inc. | Fused pyrrolocarbazoles |
| US7169802B2 (en) * | 2003-12-23 | 2007-01-30 | Cephalon, Inc. | Fused pyrrolocarbazoles |
| DE102004025726B4 (de) * | 2004-05-26 | 2006-07-06 | Roder, Hanno, Dr. | Verwendung eines spezifischen K252a-Derivats zur Verhinderung oder Behandlung der Alzheimerschen Krankheit |
| US20060058250A1 (en) * | 2004-09-10 | 2006-03-16 | Cephalon, Inc. | Methods of treating proliferative skin diseases using carbazole derivatives |
| WO2006133426A2 (en) | 2005-06-08 | 2006-12-14 | Rigel Pharmaceuticals, Inc. | Compositions and methods for inhibition of the jak pathway |
| US20070203161A1 (en) | 2006-02-24 | 2007-08-30 | Rigel Pharmaceuticals, Inc. | Compositions and methods for inhibition of the jak pathway |
| WO2007098507A2 (en) | 2006-02-24 | 2007-08-30 | Rigel Pharmaceuticals, Inc. | Compositions and methods for inhibition of the jak pathway |
| US20080021013A1 (en) * | 2006-07-21 | 2008-01-24 | Cephalon, Inc. | JAK inhibitors for treatment of myeloproliferative disorders |
| EP2124554B1 (en) * | 2006-12-14 | 2012-02-08 | Tautatis, Inc. | Compositions and methods for the treatment of cancer |
| US20100173426A1 (en) * | 2006-12-19 | 2010-07-08 | Johnson Faye M | Biomaker identifying the reactivation of stat3 after src inhibition |
| WO2008151323A1 (en) * | 2007-06-08 | 2008-12-11 | University Of Massachusetts | Mixed lineage kinases and metabolic disorders |
| HRP20170317T1 (hr) | 2008-02-15 | 2017-04-21 | Rigel Pharmaceuticals, Inc. | Spojevi pirimidin-2-amina i njihova uporaba kao inhibitora jak kinaza |
| WO2009111644A2 (en) * | 2008-03-05 | 2009-09-11 | The Regents Of The University Of Michigan | Compositions and methods for diagnosing and treating pancreatic cancer |
| US8063058B2 (en) | 2008-04-16 | 2011-11-22 | Portola Pharmaceuticals, Inc. | Inhibitors of syk and JAK protein kinases |
| US8138339B2 (en) | 2008-04-16 | 2012-03-20 | Portola Pharmaceuticals, Inc. | Inhibitors of protein kinases |
| BRPI0910668A2 (pt) | 2008-04-22 | 2019-09-24 | Portola Pharmaceutiacals Inc | inibidores de proteína quinases |
| CN103965204B (zh) | 2008-11-19 | 2016-09-07 | 赛福伦公司 | 吲唑并[5,4-a]吡咯并[3,4-c]咔唑化合物的新形式 |
| MX337849B (es) * | 2009-07-28 | 2016-03-09 | Rigel Pharmaceuticals Inc | Composiciones y metodos para inhibicion de la via jak. |
| CN102639700A (zh) | 2009-09-30 | 2012-08-15 | 哈佛大学校长及研究员协会 | 通过调节自噬增强基因产物调节自噬的方法 |
| EP2975027A1 (en) | 2010-11-01 | 2016-01-20 | Portola Pharmaceuticals, Inc. | Nicotinamides as jak kinase modulators |
| KR20140022062A (ko) * | 2011-04-07 | 2014-02-21 | 어리어드 파마슈티칼스, 인코포레이티드 | 파킨슨병을 치료하기 위한 방법 및 조성물 |
| EP2782579B1 (en) | 2011-11-23 | 2019-01-02 | Portola Pharmaceuticals, Inc. | Pyrazine kinase inhibitors |
| US9089574B2 (en) | 2011-11-30 | 2015-07-28 | Emory University | Antiviral JAK inhibitors useful in treating or preventing retroviral and other viral infections |
| WO2014058921A2 (en) | 2012-10-08 | 2014-04-17 | Portola Pharmaceuticals, Inc. | Substituted pyrimidinyl kinase inhibitors |
| EP2968322B1 (en) | 2013-03-15 | 2018-12-26 | The Trustees of Columbia University in the City of New York | Map kinase modulators and uses thereof |
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| US473939A (en) * | 1892-05-03 | mason | ||
| JPS62220196A (ja) | 1986-03-20 | 1987-09-28 | Kyowa Hakko Kogyo Co Ltd | 新規物質ｕｃｎ―０１ |
| US4816450A (en) | 1986-09-15 | 1989-03-28 | Duke University | Inhibition of protein kinase C by long-chain bases |
| US4735939A (en) | 1987-02-27 | 1988-04-05 | The Dow Chemical Company | Insecticidal activity of staurosporine |
| WO1988007045A1 (fr) | 1987-03-09 | 1988-09-22 | Kyowa Hakko Kogyo Co., Ltd. | Derives de la substance physiologiquement active k-252 |
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-
2000
- 2000-02-10 US US09/500,849 patent/US6841567B1/en not_active Expired - Lifetime
- 2000-02-11 KR KR1020017010212A patent/KR100697732B1/ko not_active Expired - Fee Related
- 2000-02-11 AU AU33604/00A patent/AU773335B2/en not_active Ceased
- 2000-02-11 PL PL00352530A patent/PL352530A1/xx not_active Application Discontinuation
- 2000-02-11 BR BR0008056-0A patent/BR0008056A/pt not_active Application Discontinuation
- 2000-02-11 NZ NZ513097A patent/NZ513097A/en not_active IP Right Cessation
- 2000-02-11 EA EA200100887A patent/EA005273B1/ru not_active IP Right Cessation
- 2000-02-11 TR TR2001/02338T patent/TR200102338T2/xx unknown
- 2000-02-11 CN CN00803647A patent/CN1350537A/zh active Pending
- 2000-02-11 CA CA002359772A patent/CA2359772C/en not_active Expired - Fee Related
- 2000-02-11 WO PCT/US2000/003476 patent/WO2000047583A1/en not_active Ceased
- 2000-02-11 EP EP00911759A patent/EP1165562A1/en not_active Ceased
- 2000-02-11 HR HR20010583A patent/HRP20010583A2/hr not_active Application Discontinuation
- 2000-02-11 SK SK1129-2001A patent/SK11292001A3/sk unknown
- 2000-02-11 CZ CZ20012878A patent/CZ20012878A3/cs unknown
- 2000-02-11 JP JP2000598503A patent/JP2003529537A/ja active Pending
-
2001
- 2001-07-20 IS IS6015A patent/IS6015A/is unknown
- 2001-08-09 NO NO20013887A patent/NO322210B1/no not_active IP Right Cessation
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2004
- 2004-01-12 US US10/755,505 patent/US7074793B2/en not_active Expired - Fee Related
-
2006
- 2006-02-02 US US11/346,524 patent/US7288650B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7288650B2 (en) | 2007-10-30 |
| WO2000047583A1 (en) | 2000-08-17 |
| US7074793B2 (en) | 2006-07-11 |
| IS6015A (is) | 2001-07-20 |
| EP1165562A1 (en) | 2002-01-02 |
| CZ20012878A3 (cs) | 2002-08-14 |
| WO2000047583A9 (en) | 2001-09-20 |
| AU3360400A (en) | 2000-08-29 |
| SK11292001A3 (sk) | 2002-04-04 |
| EA200100887A1 (ru) | 2002-02-28 |
| US20040186157A1 (en) | 2004-09-23 |
| WO2000047583A8 (en) | 2001-03-29 |
| US6841567B1 (en) | 2005-01-11 |
| US20060128780A1 (en) | 2006-06-15 |
| EA005273B1 (ru) | 2004-12-30 |
| JP2003529537A (ja) | 2003-10-07 |
| CA2359772C (en) | 2009-08-11 |
| CA2359772A1 (en) | 2000-08-17 |
| HRP20010583A2 (en) | 2002-08-31 |
| CN1350537A (zh) | 2002-05-22 |
| KR100697732B1 (ko) | 2007-03-22 |
| KR20010102085A (ko) | 2001-11-15 |
| TR200102338T2 (tr) | 2002-07-22 |
| PL352530A1 (en) | 2003-08-25 |
| NO20013887D0 (no) | 2001-08-09 |
| AU773335B2 (en) | 2004-05-20 |
| BR0008056A (pt) | 2002-04-09 |
| NO20013887L (no) | 2001-10-11 |
| NZ513097A (en) | 2004-05-28 |
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