NO320334B1 - Materialblanding av fast agarose-overtrukket agaroseinneholdende eller agarose-kollagenperle inneholdende celler som produserer et diffunderbart biologisk produkt, anvendelser derav, fremgangsmater for fremstilling derav, kondisjonert medium fremstilt ved hjelp av materialblandingen, samt fremgangsmate for a bestemme om en materialblanding er anvendelig i a undertrykke proliferasjon av cancerceller. - Google Patents

Materialblanding av fast agarose-overtrukket agaroseinneholdende eller agarose-kollagenperle inneholdende celler som produserer et diffunderbart biologisk produkt, anvendelser derav, fremgangsmater for fremstilling derav, kondisjonert medium fremstilt ved hjelp av materialblandingen, samt fremgangsmate for a bestemme om en materialblanding er anvendelig i a undertrykke proliferasjon av cancerceller. Download PDF

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Publication number
NO320334B1
NO320334B1 NO19984627A NO984627A NO320334B1 NO 320334 B1 NO320334 B1 NO 320334B1 NO 19984627 A NO19984627 A NO 19984627A NO 984627 A NO984627 A NO 984627A NO 320334 B1 NO320334 B1 NO 320334B1
Authority
NO
Norway
Prior art keywords
cancer cells
bead
cells
agarose
enclosed
Prior art date
Application number
NO19984627A
Other languages
English (en)
Norwegian (no)
Other versions
NO984627D0 (no
NO984627L (no
Inventor
Albert L Rubin
Kanti Jain
Shirin Asina
Barry Smith
Kurt Stenzel
Original Assignee
Rogosin Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/745,063 external-priority patent/US5888497A/en
Application filed by Rogosin Inst filed Critical Rogosin Inst
Publication of NO984627D0 publication Critical patent/NO984627D0/no
Publication of NO984627L publication Critical patent/NO984627L/no
Publication of NO320334B1 publication Critical patent/NO320334B1/no

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/22Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0693Tumour cells; Cancer cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/126Immunoprotecting barriers, e.g. jackets, diffusion chambers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Developmental Biology & Embryology (AREA)
  • Dispersion Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
NO19984627A 1996-04-03 1998-10-02 Materialblanding av fast agarose-overtrukket agaroseinneholdende eller agarose-kollagenperle inneholdende celler som produserer et diffunderbart biologisk produkt, anvendelser derav, fremgangsmater for fremstilling derav, kondisjonert medium fremstilt ved hjelp av materialblandingen, samt fremgangsmate for a bestemme om en materialblanding er anvendelig i a undertrykke proliferasjon av cancerceller. NO320334B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US62559596A 1996-04-03 1996-04-03
US08/745,063 US5888497A (en) 1996-04-03 1996-11-07 Agarose coated agarose beads containing cancer cells that produce material which suppresses cancer cell proliferation
PCT/US1997/004548 WO1997036495A1 (en) 1996-04-03 1997-03-21 Implantable agarose-collagen beads containing cells which produce a diffusible biological product, and uses thereof

Publications (3)

Publication Number Publication Date
NO984627D0 NO984627D0 (no) 1998-10-02
NO984627L NO984627L (no) 1998-11-30
NO320334B1 true NO320334B1 (no) 2005-11-21

Family

ID=27089961

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19984627A NO320334B1 (no) 1996-04-03 1998-10-02 Materialblanding av fast agarose-overtrukket agaroseinneholdende eller agarose-kollagenperle inneholdende celler som produserer et diffunderbart biologisk produkt, anvendelser derav, fremgangsmater for fremstilling derav, kondisjonert medium fremstilt ved hjelp av materialblandingen, samt fremgangsmate for a bestemme om en materialblanding er anvendelig i a undertrykke proliferasjon av cancerceller.

Country Status (16)

Country Link
EP (2) EP0914043B1 (zh)
JP (2) JP3765039B2 (zh)
CN (2) CN1119080C (zh)
AT (2) ATE250858T1 (zh)
AU (1) AU722109C (zh)
CA (1) CA2250880C (zh)
DE (2) DE69738170T2 (zh)
DK (2) DK0914043T3 (zh)
ES (2) ES2290390T3 (zh)
FI (1) FI120332B (zh)
HK (2) HK1019037A1 (zh)
IL (1) IL126442A0 (zh)
NO (1) NO320334B1 (zh)
NZ (2) NZ331960A (zh)
PT (1) PT914043E (zh)
WO (1) WO1997036495A1 (zh)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6303151B1 (en) * 1996-04-03 2001-10-16 The Rogosin Institute Cancer-cell proliferation-suppressing material produced by cancer cells restricted by entrapment
US7297331B2 (en) 1996-04-03 2007-11-20 The Rogosin Institute Beads containing restricted cancer cells producing material suppressing cancer cell proliferation
US6224912B1 (en) * 1996-04-03 2001-05-01 The Rogo Institute Cancer-cell proliferation-suppressing material produced by cancer cells restricted by entrapment
NO983911D0 (no) 1998-08-26 1998-08-26 Norsk Hydro As Alginatkapsler til bruk ved behandling av hjernesvulst
AU2003264652B2 (en) * 1998-11-09 2006-09-14 The Rogosin Institute Compositions of restricted cells capable of rapid growth which produce proliferation suppressive materials, and uses thereof
US8257715B1 (en) 2004-08-26 2012-09-04 University Of Notre Dame Tissue vaccines and uses thereof
US9308252B2 (en) 2005-10-27 2016-04-12 Cook Biotech, Inc. Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins
US8802113B2 (en) 2005-10-27 2014-08-12 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
US8778362B2 (en) 2005-10-27 2014-07-15 University Of Notre Dame Anti-tumor/cancer heterologous acellular collagenous preparations and uses thereof
US8778360B2 (en) * 2005-10-27 2014-07-15 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
US9283266B2 (en) 2008-02-28 2016-03-15 University Of Notre Dame Metastasis inhibition preparations and methods
US8846059B2 (en) 2009-12-08 2014-09-30 University Of Notre Dame Extracellular matrix adjuvant and methods for prevention and/or inhibition of ovarian tumors and ovarian cancer
HUE034618T2 (en) * 2012-01-31 2018-02-28 The Rogosin Inst Inc An improved process for producing macros
JP2021511790A (ja) * 2018-02-02 2021-05-13 ウェイク・フォレスト・ユニバーシティ・ヘルス・サイエンシーズWake Forest University Health Sciences 免疫療法に関するオルガノイドならびにそれを調製および使用する方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE441009B (sv) * 1982-03-08 1985-09-02 Kjell Nilsson Sett att immobilisera levande biomaterial i perlformiga polymerer
US4798786A (en) * 1982-05-06 1989-01-17 Stolle Research And Development Corporation Living cells encapsulated in crosslinked protein
CA1196862A (en) * 1983-06-01 1985-11-19 Anthony M.F. Sun Microencapsulation of living tissue and cells
US4663286A (en) * 1984-02-13 1987-05-05 Damon Biotech, Inc. Encapsulation of materials
SE8604684L (sv) * 1986-11-03 1988-05-04 Excorim Kommanditbolag Sett att belegga fasta partiklar med en hydrofil gel samt genom settet belagda partiklar
JP2691557B2 (ja) * 1988-04-15 1997-12-17 興研株式会社 人の悪性腫瘍細胞増殖抑制剤
US5053332A (en) * 1989-07-24 1991-10-01 Cook Richard B Agarose beads, preferably incorporating biological materials
US5241051A (en) * 1992-04-24 1993-08-31 Research Development Foundation Oncoinhibin
ES2260568T3 (es) * 1994-01-13 2006-11-01 The Rogosin Institute Celulas secretoras macroencapsuladas.
US5651980A (en) * 1994-04-15 1997-07-29 Biohybrid Technologies, Inc. Methods of use of uncoated gel particles

Also Published As

Publication number Publication date
EP0914043B1 (en) 2003-10-01
CA2250880C (en) 2008-01-15
EP0914043A1 (en) 1999-05-12
AU2218897A (en) 1997-10-22
CN1119080C (zh) 2003-08-27
EP0914043A4 (en) 2001-08-29
CN1215309A (zh) 1999-04-28
FI981957A (fi) 1998-12-02
NO984627D0 (no) 1998-10-02
DE69738170D1 (de) 2007-11-08
JP4480152B2 (ja) 2010-06-16
CA2250880A1 (en) 1997-10-09
NZ331960A (en) 1999-10-28
JP2005104987A (ja) 2005-04-21
DE69738170T2 (de) 2008-01-24
EP1382346A1 (en) 2004-01-21
JP3765039B2 (ja) 2006-04-12
PT914043E (pt) 2004-02-27
HK1066026A1 (en) 2005-03-11
CN1296477C (zh) 2007-01-24
JP2001503380A (ja) 2001-03-13
EP1382346B1 (en) 2007-09-26
NZ337109A (en) 2004-12-24
CN1495253A (zh) 2004-05-12
ES2290390T3 (es) 2008-02-16
IL126442A0 (en) 1999-08-17
WO1997036495A1 (en) 1997-10-09
FI120332B (fi) 2009-09-30
DE69725317D1 (de) 2003-11-06
AU722109B2 (en) 2000-07-20
ATE250858T1 (de) 2003-10-15
DE69725317T2 (de) 2004-07-29
ES2206696T3 (es) 2004-05-16
DK1382346T3 (da) 2008-01-28
NO984627L (no) 1998-11-30
AU722109C (en) 2001-07-19
DK0914043T3 (da) 2004-02-09
HK1019037A1 (en) 2000-01-21
FI981957A0 (fi) 1998-09-11
ATE374034T1 (de) 2007-10-15

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