NO315163B1 - Immunologisk aktive peptider, DNA-sekvenser som koder for peptidene og anvendelse av disse i et testsett for påvisning av virus somforårsaker immunsvikt - Google Patents

Immunologisk aktive peptider, DNA-sekvenser som koder for peptidene og anvendelse av disse i et testsett for påvisning av virus somforårsaker immunsvikt Download PDF

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Publication number
NO315163B1
NO315163B1 NO19950668A NO950668A NO315163B1 NO 315163 B1 NO315163 B1 NO 315163B1 NO 19950668 A NO19950668 A NO 19950668A NO 950668 A NO950668 A NO 950668A NO 315163 B1 NO315163 B1 NO 315163B1
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Norway
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type
seq
unknown
peptide
sequence
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NO19950668A
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English (en)
Norwegian (no)
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NO950668L (no
NO950668D0 (no
Inventor
Stefan Brust
Stefan Knapp
Manfred Gerken
Lutz G Guertler
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Dade Behring Marburg Gmbh
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Application filed by Dade Behring Marburg Gmbh filed Critical Dade Behring Marburg Gmbh
Publication of NO950668D0 publication Critical patent/NO950668D0/no
Publication of NO950668L publication Critical patent/NO950668L/no
Publication of NO315163B1 publication Critical patent/NO315163B1/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036Retroviridae, e.g. leukemia viruses
    • C07K16/1045Lentiviridae, e.g. HIV, FIV, SIV
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • C12Q1/703Viruses associated with AIDS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • AIDS & HIV (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO19950668A 1994-02-23 1995-02-22 Immunologisk aktive peptider, DNA-sekvenser som koder for peptidene og anvendelse av disse i et testsett for påvisning av virus somforårsaker immunsvikt NO315163B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4405810A DE4405810A1 (de) 1994-02-23 1994-02-23 Von einem Retrovirus aus der HIV-Gruppe abgeleitete Peptide und deren Verwendung

Publications (3)

Publication Number Publication Date
NO950668D0 NO950668D0 (no) 1995-02-22
NO950668L NO950668L (no) 1995-08-24
NO315163B1 true NO315163B1 (no) 2003-07-21

Family

ID=6510992

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19950668A NO315163B1 (no) 1994-02-23 1995-02-22 Immunologisk aktive peptider, DNA-sekvenser som koder for peptidene og anvendelse av disse i et testsett for påvisning av virus somforårsaker immunsvikt

Country Status (12)

Country Link
US (4) US5830634A (ko)
EP (1) EP0673948B1 (ko)
JP (1) JP2948121B2 (ko)
KR (1) KR100230880B1 (ko)
AT (1) ATE173275T1 (ko)
AU (1) AU697121B2 (ko)
BR (1) BR9500732B8 (ko)
CA (1) CA2143163C (ko)
DE (2) DE4405810A1 (ko)
DK (1) DK0673948T3 (ko)
ES (1) ES2124922T3 (ko)
NO (1) NO315163B1 (ko)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2107732C (en) * 1992-10-06 2003-04-08 Lutz G. Gurtler Retrovirus from the hiv group and its use
DE4405810A1 (de) * 1994-02-23 1995-08-24 Behringwerke Ag Von einem Retrovirus aus der HIV-Gruppe abgeleitete Peptide und deren Verwendung
DE19505262C2 (de) * 1995-02-16 1998-06-18 Behring Diagnostics Gmbh Retrovirus aus der HIV-Gruppe und dessen Verwendung
WO1996040763A2 (en) * 1995-06-07 1996-12-19 Abbott Laboratories Peptides for hiv-1 detection
US5977299A (en) * 1997-04-07 1999-11-02 Dade Behring Marburg Gmbh Activated peptides and conjugates
BRPI9809078B8 (pt) * 1997-04-09 2021-05-25 Bio Rad Innovations peptídeo sintético utilizáveis nos testes biológicos para a detecção das infecções devido aos vírus hiv1 do grupo o, composição que os compreende, processo de imunodosagem in vitro e kit de diagnóstico.
DE19718361A1 (de) 1997-05-02 1998-11-05 Dade Behring Marburg Gmbh Immunoassay zur Aviditätsbestimmung von Immunglobulinen
US5891994A (en) * 1997-07-11 1999-04-06 Thymon L.L.C. Methods and compositions for impairing multiplication of HIV-1
WO1999038887A1 (en) * 1998-01-28 1999-08-05 Universal Healthwatch, Inc. Divergent hiv-1 peptides
WO1999062945A2 (en) * 1998-06-05 1999-12-09 Peptide Solutions, Inc. Peptide antigens for detection of hiv, hcv and other microbial infections
NZ508812A (en) * 1998-06-12 2002-11-26 Aventis Pasteur Peptides for the prevention or treatment of HIV
US6911527B1 (en) 1999-01-11 2005-06-28 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services HIV related peptides
EP1159297A2 (en) * 1999-01-11 2001-12-05 THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES Hiv related peptides
US6399067B1 (en) * 2000-04-28 2002-06-04 Thymon L.L.C. Methods and compositions for impairing multiplication of HIV-1
CA2450548C (en) 2001-06-15 2012-05-01 F. Hoffmann-La Roche Ag Method for the recombinant production of peptidic antiviral fusion inhibitors, and acetylation of gb41 fragments
US8043152B2 (en) * 2003-07-03 2011-10-25 Igt Methods and system for providing paper-based outcomes
CA2547750C (en) * 2003-12-19 2014-04-08 Gen-Probe Incorporated Compositions, methods and kits for detecting the nucleic acids of hiv-1 and hiv-2
US20050208482A1 (en) 2004-03-16 2005-09-22 Cohen David I Tat-based immunomodulatory compositions and methods for their discovery and use
US7563437B2 (en) 2005-02-15 2009-07-21 Thymon, Llc Methods and compositions for impairing multiplication of HIV-1
WO2007064859A2 (en) * 2005-11-29 2007-06-07 University Of Pittsburgh Of The Commonwealth System Of Higher Education Compound and method for suppressing retroviral replication
DK2411043T3 (da) 2009-03-23 2013-10-21 Pin Pharma Inc Behandling af cancer med immunostimulatorisk hiv tat derivat-polypeptider
US8438898B2 (en) * 2009-07-01 2013-05-14 Edwards Lifesciences Corporation Calibrant infusion fluid source preparation
ES2625406T3 (es) 2010-03-25 2017-07-19 Oregon Health & Science University Glicoproteínas de CMV y vectores recombinantes
ES2667425T3 (es) 2011-06-10 2018-05-10 Oregon Health & Science University Glucoproteínas y vectores recombinantes de CMV
EP2568289A3 (en) 2011-09-12 2013-04-03 International AIDS Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
ES2631608T3 (es) 2012-06-27 2017-09-01 International Aids Vaccine Initiative Variante de la glicoproteína Env del VIH-1
EP2848937A1 (en) 2013-09-05 2015-03-18 International Aids Vaccine Initiative Methods of identifying novel HIV-1 immunogens
AU2014329393B2 (en) 2013-10-04 2020-04-30 Pin Pharma, Inc. Immunostimulatory HIV Tat derivative polypeptides for use in cancer treatment
EP2873423B1 (en) 2013-10-07 2017-05-31 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
EP3069730A3 (en) 2015-03-20 2017-03-15 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
US9931394B2 (en) 2015-03-23 2018-04-03 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
CN108997482A (zh) * 2018-08-09 2018-12-14 东莞市朋志生物科技有限公司 用于检测hiv-1的合成肽

Family Cites Families (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9328391B1 (en) 1984-08-22 2016-05-03 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Cloning and expression of HIV-1 DNA
DE3587181T2 (de) * 1984-10-18 1993-06-24 Centre Nat Rech Scient F antigene vom menschlichen immunodefizienz-virus und deren verwendungen.
CA1341482C (en) 1984-10-31 2005-05-10 Paul A. Luciw Process for preparing fragments of aids-associated retroviruses
CA1247082A (en) 1984-11-09 1988-12-20 Myron E. Essex Assay for detecting infection by human t-cell leukemia virus
ATE138100T1 (de) 1984-12-24 1996-06-15 Genentech Inc Fusionen von aids-verwandten polypeptiden
US4774175A (en) 1985-03-01 1988-09-27 Centocor, Inc. Immunochemical methods for the detection of antibody against HTLV-III
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
IE64785B1 (en) 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
DK171119B1 (da) 1985-04-19 1996-06-17 Hoffmann La Roche AIDS-viruskappeprotein, ekspressionsvektor bærende viruskappeproteinet, transformanter transformeret med ekspressionsvektoren, fremgangsmåde til fremstilling af viruskappeproteinet, fremgangsmåde til detektion af AIDS-antistoffer, fremgangsmåde til bestemmelse af AIDS-virus, vaccine mod AIDS, antistoffer mod viruskappeproteinet samt anvendelse af dette til fremstilling af en vaccine og til testnin
US4629783A (en) * 1985-04-29 1986-12-16 Genetic Systems Corporation Synthetic antigen for the detection of AIDS-related disease
AU6104586A (en) 1985-08-12 1987-02-19 Malcolm A. Martin Aids protein using trple gene
US4803156A (en) 1985-09-11 1989-02-07 New York Blood Center Peptide-beta-lactamase conjugates for enzyme-linked immunoassays
NZ217645A (en) 1985-09-25 1991-11-26 Oncogen Recombinant viruses expressing lav/htlv-iii related epitopes and vaccine formulations
GB8525615D0 (en) 1985-10-17 1985-11-20 Hoffmann La Roche Polypeptides
ATE87103T1 (de) 1985-12-17 1993-04-15 Akzo Nv Immunochemisches reagenz.
US5079342A (en) 1986-01-22 1992-01-07 Institut Pasteur Cloned DNA sequences related to the entire genomic RNA of human immunodeficiency virus II (HIV-2), polypeptides encoded by these DNA sequences and use of these DNA clones and polypeptides in diagnostic kits
NZ219024A (en) 1986-01-22 1990-04-26 Pasteur Institut Hiv-2 retrovirus protein and nucleic acid sequences and detection methods
US4734362A (en) 1986-02-03 1988-03-29 Cambridge Bioscience Corporation Process for purifying recombinant proteins, and products thereof
US4925784A (en) 1986-04-04 1990-05-15 Hoffmann-La Roche Inc. Expression and purification of an HTLV-III gag/env gene protein
US5126399A (en) 1986-04-30 1992-06-30 Board Of Regents, The University Of Texas System Methods and compositions for the preparation and use of site-directed immunologic reagents
JPH01501547A (ja) 1986-06-12 1989-06-01 バイオジェン ナームローズ ベンノットシャップ Hiv感染の病因に関するペプチド
US5034511A (en) 1987-04-13 1991-07-23 Institut Pasteur Variant of LAV viruses
US5030714A (en) 1986-06-23 1991-07-09 Institut Pasteur Variant of LAV viruses
EP0255190A3 (en) 1986-08-01 1990-08-29 Repligen Corporation Recombinant polypeptides and their uses, inclusing assay for aids virus
IL84154A0 (en) 1986-10-16 1988-03-31 Microgenesys Inc Polypeptides derived from the envelope gene of human immunodeficiency virus in recombinant baculovirus infected insect cells and vaccines against acquired immune deficiency syndrome containing the same
WO1988003562A1 (en) 1986-11-01 1988-05-19 Oxford Gene Systems Limited Particulate hybrid hiv antigens
EP0269520A3 (fr) 1986-11-21 1988-08-24 Institut Pasteur Rétrovirus du type HIV-2 susceptible de provoquer le sida, et ses constituants antigéniques et nucléiques
GB8629116D0 (en) 1986-12-05 1987-01-14 Hoffmann La Roche Env/gag polypeptides
JPS63258575A (ja) 1986-12-15 1988-10-26 レプリゲン コーポレーション 昆虫細胞中でつくられる組換えhivエンベロープタンパク
US5030449A (en) 1988-07-21 1991-07-09 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Synthetic vaccine against AIDS virus
DE3787002T2 (de) 1986-12-30 1993-11-25 Us Health Synthetische Peptide, die zelluläre Immunität gegen den AIDS-Virus und dessen Proteine erzeugen.
ATE154808T1 (de) 1987-01-16 1997-07-15 Pasteur Institut Peptide mit den immunologischen eigenschaften von hiv-2
EP0300031A4 (en) 1987-01-28 1990-05-14 Ortho Pharma Corp IMMUNE SUPPRESSIVE PEPTIDES AND METHOD FOR THEIR USE.
US5141867A (en) 1987-02-02 1992-08-25 E. I. Du Pont De Nemours And Company Nucleotide sequence encoding a human immunodeficiency virus antigen
NO881151L (no) 1987-03-27 1988-09-28 Syntello Ab Syntetisk hiv-1-antigen.
AU1711888A (en) 1987-04-24 1988-12-02 Biogen, Inc. Immunotherapeutic methods and compositions
SE8701765L (sv) 1987-04-28 1988-10-29 Statens Bakteriologiska Lab Analysmetod och medel foer denna
AU620330B2 (en) 1987-05-29 1992-02-20 Smithkline Beckman Corporation Immunodiagnostic assays using chimeric antigens
GB8714802D0 (en) 1987-06-24 1987-07-29 Proteus Biotech Ltd Synthetic polypeptides
DE3724016A1 (de) 1987-07-21 1989-02-02 Hans Prof Dr Dr Wolf Methoden fuer die gentechnologische produktion von antigenen sowie deren nutzung in einem neuen ansatz fuer bestaetigungsteste fuer antikoerper am beispiel des humanen immundefizienz-virus (hiv)
IL87391A0 (en) 1987-08-27 1989-01-31 Repligen Corp Hiv proteins and peptides,dna coding therefor,vectors comprising such dna,the use of the proteins and peptides in diagnosis of aids and vaccine compositions containing them
US5128319A (en) 1987-08-28 1992-07-07 Board Of Regents, The University Of Texas System Prophylaxis and therapy of acquired immunodeficiency syndrome
AU2914889A (en) 1987-08-28 1989-04-17 Board Of Regents, The University Of Texas System Prophylaxis and therapy of acquired immunodeficiency syndrome
IE63455B1 (en) 1987-09-04 1995-04-19 Int Murex Tech Corp Immunoassay and biological constructs for use therein
US5013548A (en) 1987-09-08 1991-05-07 Duke University Production of antibodies to HIV
US4863202A (en) * 1987-09-16 1989-09-05 Oldford William G Fluid connector assembly
EP0311228A3 (en) 1987-10-09 1990-05-02 Repligen Corporation Recombinant polypeptides and their uses, including assay for aids virus
US5019510A (en) * 1987-10-28 1991-05-28 Institut Pasteur Isolation, molecular cloning and sequencing of an HIV-1 isolate from a Gabonese donor
ATE128716T1 (de) 1987-11-24 1995-10-15 Abbott Lab Hiv-peptide und methoden für den nachweis von hiv.
EP0323157A3 (en) 1987-12-24 1990-07-25 The University Of Melbourne Antiviral compounds and methods
JPH01179687A (ja) 1987-12-30 1989-07-17 Chemo Sero Therapeut Res Inst Hiv融合蛋白質
IL89118A0 (en) 1988-02-03 1989-08-15 Microgenesys Inc Vaccine containing polypeptides derived from the envelope gene of human immunodeficiency virus type 1
EP0330359A3 (en) 1988-02-25 1991-06-05 Bio-Rad Laboratories, Inc. Composition useful in the diagnosis and treating of hiv-1 infection
US5312737A (en) 1988-03-11 1994-05-17 Abbott Laboratories CKS method of HCV protein synthesis
US5124255A (en) 1988-03-11 1992-06-23 Abbott Laboratories CKS method of protein synthesis
WO1989009785A1 (en) 1988-04-07 1989-10-19 The Trustees Of The University Of Alabama Peptides inhibitors of hiv induced cell fusions and syncytia formation
WO1989010416A1 (en) 1988-04-20 1989-11-02 Trustees Of The University Of Pennsylvania PROTECTIVE PEPTIDES DERIVED FROM HUMAN IMMUNODEFICIENCY VIRUS-1 gp160
DE58905660D1 (de) 1988-04-25 1993-10-28 Hoffmann La Roche Diagnose-Hilfsmittel.
JP2758900B2 (ja) 1988-05-16 1998-05-28 正憲 速水 ヒト免疫不全ウイルス2型の遺伝子rnaに相補性を示すdna
EP1369427A3 (en) * 1988-06-09 2004-05-12 Innogenetics N.V. HIV-3 retrovirus strains and their use
EP0345792A3 (en) 1988-06-10 1991-05-02 F. Hoffmann-La Roche Ag Htlv-i / hiv-1 fusion proteins
FR2635532B1 (fr) 1988-07-29 1992-05-22 Pasteur Institut Particules hbsag recombinantes hybrides : caracteristiques morphologiques de l'antigene hbsag contenant 1 sequence immunogene induisant des anticorps neutralisants diriges contre hiv ou susceptible d'etre reconnue par de tels anticorps; sequences nucleotidiques codant pour de telles particules; vaccins les contenant
US5135736A (en) 1988-08-15 1992-08-04 Neorx Corporation Covalently-linked complexes and methods for enhanced cytotoxicity and imaging
EP0362909A3 (en) 1988-08-26 1990-11-14 Akzo N.V. Synthetic polypeptides immunochemically reactive with hiv-antibodies
WO1990002568A1 (en) 1988-09-13 1990-03-22 Chiron Corporation Hiv-1 envelope muteins lacking hypervariable domains
JPH04502760A (ja) 1988-10-03 1992-05-21 レプリゲン・コーポレーション エイズの診断,予防および治療に有効な新規hiv蛋白質およびペプチド
CA2003383A1 (en) 1988-11-23 1990-05-23 Sushil G. Devare Synthetic dna derived recombinant hiv antigens
GB8828098D0 (en) 1988-12-01 1989-01-05 Wellcome Found Peptides
US5223423A (en) 1989-03-31 1993-06-29 United States Of America Characterization of replication competent human immunodeficiency type 2 proviral clone hiv-2sbl/isy
FR2646606B1 (fr) 1989-05-03 1994-06-17 Inst Nat Sante Rech Med Retrovirus hautement cytopathogenique hiv-ndk. fragment d'adn de ce retrovirus, procede de preparation d'une proteine et/ou enzyme de ce virus et leurs utilisations
CA2025634A1 (en) 1989-09-19 1991-03-20 Thomas Fuerst Peptides including ctl epitopes of hiv proteins and use thereof
CA2066607A1 (en) 1989-09-22 1991-03-23 Thomas Kieber-Emmons Peptides associated with the cd4 binding region of gp120 and their methods of use
IE904083A1 (en) 1989-11-13 1991-05-22 Cambridge Biotech Corp Diagnostic proteins to test for more than one antibody
DE4002636A1 (de) 1990-01-30 1991-08-01 Boehringer Mannheim Gmbh Expression von hiv1- und 2-polypeptiden und deren verwendung
CA2035576A1 (en) 1990-02-07 1991-08-08 Alexander R. Neurath Conformational epitopes of human immunodeficiency virus envelope glycoprotein gp120 hiv-1
DE69111440T2 (de) 1990-04-03 1996-03-28 Genentech Inc Methoden und zusammensetzungen zur impfung gegen hiv.
CA2078545A1 (en) 1990-04-03 1991-10-04 Timothy J. Gregory Hiv envelope polypeptides
US5013458A (en) 1990-04-06 1991-05-07 Rdp Company Process and apparatus for pathogen reduction in waste
ATE147782T1 (de) 1990-07-12 1997-02-15 Harvard College Primaten-lentivirus impfstoffe
CA2050817A1 (en) 1990-09-24 1992-03-25 Emilio A. Emini Hiv-neutralizing rat monoclonal antibodies against pb-1
WO1992005800A1 (en) 1990-09-27 1992-04-16 Syntello Vaccin Development Kb Peptides for use in vaccination and induction of neutralizing antibodies against human immunodeficiency virus
CA2093427C (en) 1990-10-17 2008-01-15 Marvin S. Reitz, Jr. Molecular clones of hiv-1 and uses thereof
FR2676071B1 (fr) 1991-05-02 1994-11-18 Transgene Sa Nouveau variant gp160 non-clivable, soluble, de forme hybride.
FR2677364A1 (fr) 1991-06-05 1992-12-11 Pasteur Institut Sequences peptidiques de la glycoproteine externe d'enveloppe du retrovirus hiv-1.
DE4318186C2 (de) 1993-06-01 2002-07-25 Dade Behring Marburg Gmbh Retrovirus aus der HIV-Gruppe und dessen Verwendung
CA2107732C (en) * 1992-10-06 2003-04-08 Lutz G. Gurtler Retrovirus from the hiv group and its use
DE4405810A1 (de) * 1994-02-23 1995-08-24 Behringwerke Ag Von einem Retrovirus aus der HIV-Gruppe abgeleitete Peptide und deren Verwendung

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AU1353295A (en) 1995-09-07
ES2124922T3 (es) 1999-02-16
US20050271678A1 (en) 2005-12-08
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US5830634A (en) 1998-11-03
NO950668D0 (no) 1995-02-22
US6335158B2 (en) 2002-01-01
US7803524B2 (en) 2010-09-28
EP0673948A1 (de) 1995-09-27
US6869608B2 (en) 2005-03-22
BR9500732B1 (pt) 2012-09-04
CA2143163A1 (en) 1995-08-24
US20010009667A1 (en) 2001-07-26
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CA2143163C (en) 1999-12-28
AU697121B2 (en) 1998-09-24
US20020123039A1 (en) 2002-09-05
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DK0673948T3 (da) 1999-07-26
BR9500732A (pt) 1995-10-24
KR950032278A (ko) 1995-12-20

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