NO310855B1 - Fremgangsmåte for rensing av protein - Google Patents
Fremgangsmåte for rensing av protein Download PDFInfo
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- NO310855B1 NO310855B1 NO19943546A NO943546A NO310855B1 NO 310855 B1 NO310855 B1 NO 310855B1 NO 19943546 A NO19943546 A NO 19943546A NO 943546 A NO943546 A NO 943546A NO 310855 B1 NO310855 B1 NO 310855B1
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- protein
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- chromatography
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- ethylene glycol
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- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
- B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/32—Bonded phase chromatography
- B01D15/325—Reversed phase
- B01D15/327—Reversed phase with hydrophobic interaction
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/34—Size selective separation, e.g. size exclusion chromatography, gel filtration, permeation
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
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- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
- B01D15/361—Ion-exchange
- B01D15/362—Cation-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction
- B01D15/361—Ion-exchange
- B01D15/363—Anion-exchange
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| US07/857,022 US5252216A (en) | 1992-03-24 | 1992-03-24 | Protein purification |
| PCT/US1993/002732 WO1993018835A1 (fr) | 1992-03-24 | 1993-03-24 | Purification de proteines |
Publications (3)
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| NO943546D0 NO943546D0 (no) | 1994-09-23 |
| NO943546L NO943546L (no) | 1994-11-23 |
| NO310855B1 true NO310855B1 (no) | 2001-09-10 |
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| NO19943546A NO310855B1 (no) | 1992-03-24 | 1994-09-23 | Fremgangsmåte for rensing av protein |
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| EP (1) | EP0643608B1 (fr) |
| JP (1) | JP3335629B2 (fr) |
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| AT (1) | ATE193839T1 (fr) |
| AU (1) | AU659936B2 (fr) |
| CA (1) | CA2132533C (fr) |
| DE (1) | DE69328864T2 (fr) |
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| MX (1) | MX9301655A (fr) |
| NO (1) | NO310855B1 (fr) |
| NZ (1) | NZ251601A (fr) |
| PT (1) | PT643608E (fr) |
| TW (1) | TW321651B (fr) |
| WO (1) | WO1993018835A1 (fr) |
| ZA (1) | ZA932015B (fr) |
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| US6395888B1 (en) * | 1996-02-01 | 2002-05-28 | Gilead Sciences, Inc. | High affinity nucleic acid ligands of complement system proteins |
| DE4331358A1 (de) * | 1992-10-12 | 1994-04-14 | Braun Melsungen Ag | Verfahren zur quantitativen selektiven Entfernung oder präparativen Gewinnung von Tumor-Nekrose-Faktor (TNF) oder/und Lipopolysacchariden (LPS) aus wäßrigen Flüssigkeiten |
| ATE213639T1 (de) * | 1993-07-09 | 2002-03-15 | Avant Immunotherapeutics Inc | Proteinreinigung |
| US5679546A (en) * | 1993-09-24 | 1997-10-21 | Cytomed, Inc. | Chimeric proteins which block complement activation |
| US5429746A (en) * | 1994-02-22 | 1995-07-04 | Smith Kline Beecham Corporation | Antibody purification |
| DE19515554C2 (de) * | 1995-04-27 | 1999-06-17 | Braun Melsungen Ag | Verwendung eines Mittels und Vorrichtung zur simultanen extrakorporalen Elimination von Tumor-Nekrose-Faktor alpha und bakteriellen Lipopolysacchariden aus Vollblut oder/und Blutplasma |
| EP0835446B1 (fr) * | 1995-06-26 | 2003-04-09 | Perseptive Biosystems, Inc. | Selection et analyse moleculaires multidimensionnelles automatiques et rapides a flux continu |
| EP1300679A3 (fr) * | 1995-06-26 | 2004-04-14 | Perseptive Biosystems, Inc. | Sélection et analyse moléculaire |
| GB9515196D0 (en) * | 1995-07-25 | 1995-09-20 | Matthey Rustenburg Refines | Interseparation of platignum group metals |
| WO1999000168A1 (fr) * | 1997-06-27 | 1999-01-07 | Life Technologies, Inc. | Dispositif et procede de concentration et purification de molecules biologiques en une etape |
| US5993653C1 (en) * | 1997-08-11 | 2001-11-06 | Phenomenex | Composition and column used in hplc |
| US6869796B2 (en) * | 1997-08-26 | 2005-03-22 | Avaris Ab | Method of introducing organic molecules into target cells |
| US20070122904A1 (en) * | 2000-09-29 | 2007-05-31 | Unisearch Limited | Method and apparatus for culturing cells |
| US6855263B2 (en) * | 2002-07-23 | 2005-02-15 | Nuvue Technologies, Inc. | Rapid process for purification and concentration of plasmin |
| DE10255508A1 (de) * | 2002-11-27 | 2004-06-17 | Forschungszentrum Jülich GmbH | Verfahren zur Kultivierung von Zellen zur Produktion von Substanzen |
| US6913695B2 (en) * | 2003-07-08 | 2005-07-05 | Bayer Healthcare Llc | Sanitization of chromatographic media |
| WO2005012349A2 (fr) * | 2003-08-01 | 2005-02-10 | Lorantis Limited | Processus |
| US7329353B2 (en) * | 2004-01-23 | 2008-02-12 | Amgen Inc. | LC/MS method of analyzing high molecular weight proteins |
| US7803931B2 (en) | 2004-02-12 | 2010-09-28 | Archemix Corp. | Aptamer therapeutics useful in the treatment of complement-related disorders |
| NZ552264A (en) * | 2004-07-20 | 2010-03-26 | Symphogen As | A procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line |
| JPWO2006011580A1 (ja) * | 2004-07-27 | 2008-05-01 | ジェノミディア株式会社 | ウイルスエンベロープの精製方法 |
| WO2006016161A1 (fr) * | 2004-08-12 | 2006-02-16 | Lipoxen Technologies Limited | Fractionnement |
| EP1738763A1 (fr) | 2005-06-30 | 2007-01-03 | AVANT Immunotherapeutics, Inc. | Utilisation de proteines d'inhibition du système complémentaire pour le traitement d'und lesion de la moelle épinière |
| WO2007053235A1 (fr) * | 2005-11-04 | 2007-05-10 | Sachem, Inc. | Processus chromatographie par deplacement a echange de cations et composes cationiques organiques servant de composes deplaceurs dans un tel processus |
| EP4159220A1 (fr) | 2006-03-08 | 2023-04-05 | Archemix LLC | Aptamères de liaison complémentaires et agents anti-c5 utiles dans le traitement des troubles oculaires |
| US20100222560A1 (en) | 2009-03-02 | 2010-09-02 | Zymo Research Corporation | Universal column |
| EP3202785B1 (fr) | 2009-10-26 | 2024-05-08 | F. Hoffmann-La Roche AG | Procédé de production d'immunoglobuline glycosylée |
| WO2012037370A1 (fr) | 2010-09-15 | 2012-03-22 | Celldex Therapeutics, Inc. | TRAITEMENT DE NÉPHROPATHIES CHRONIQUES AU MOYEN DU RÉCEPTEUR DU COMPLÉMENT SOLUBLE DE TYPE I (sCR1) |
| WO2012048298A2 (fr) | 2010-10-08 | 2012-04-12 | Caridianbct, Inc. | Procédés et systèmes de culture et de récolte de cellules dans un système de bioréacteur à fibres creuses avec conditions de régulation |
| CA2815237C (fr) | 2010-10-27 | 2018-10-09 | Celldex Therapeutics, Inc. | Methode pour ameliorer la fonction de transplantation a l'aide d'un recepteur de complement soluble de type 1 (scr1) |
| JP6830059B2 (ja) | 2014-09-26 | 2021-02-17 | テルモ ビーシーティー、インコーポレーテッド | スケジュール化された細胞フィーディング |
| US11965175B2 (en) | 2016-05-25 | 2024-04-23 | Terumo Bct, Inc. | Cell expansion |
| US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
| CN117247899A (zh) | 2017-03-31 | 2023-12-19 | 泰尔茂比司特公司 | 细胞扩增 |
| WO2023240322A1 (fr) * | 2022-06-17 | 2023-12-21 | CSL Innovation Pty Ltd | Purification d'un récepteur du complément soluble et variants de celui-ci |
Family Cites Families (15)
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| DE2319495C2 (de) * | 1973-04-17 | 1985-01-10 | Yeda Research And Development Co., Ltd., Rehovot | Verfahren zum selektiven, reversiblen Binden von Biomolekülen an ein Adsorbens in einer chromatographischen Säule |
| US4000098A (en) * | 1974-08-16 | 1976-12-28 | Palo Alto Medical Research Foundation | Separation of proteins by hydrophobic adsorption |
| DE3149360A1 (de) * | 1981-12-12 | 1983-06-16 | Biotest-Serum-Institut Gmbh, 6000 Frankfurt | "verfahren zur reinigung und/oder phytohaemagglutinin-abtrennung von human-interleukin-2" |
| US4920196A (en) * | 1982-07-30 | 1990-04-24 | Genentech, Inc. | Human lymphotoxin |
| US4908434A (en) * | 1984-04-25 | 1990-03-13 | Sloan-Kettering Institute For Cancer Research | Process for preparing purified interleukin-2 |
| US4743680A (en) * | 1985-02-01 | 1988-05-10 | New York University | Method for purifying antihemophilic factor |
| US4894439A (en) * | 1986-05-22 | 1990-01-16 | Cetus Corporation | N-terminal derivatives of tumor necrosis factor purified by microporous PTFE membranes |
| AU597924B2 (en) * | 1985-12-11 | 1990-06-14 | Natinco Nv | Solubilization of protein aggregates |
| US4770781A (en) * | 1986-03-03 | 1988-09-13 | Merck & Co., Inc. | Purification of human interleukin-1 species |
| US4771128A (en) * | 1986-10-10 | 1988-09-13 | Cetus Corporation | Method of purifying toxin conjugates using hydrophobic interaction chromatography |
| AU609824B2 (en) * | 1987-06-15 | 1991-05-09 | Southern Cross Biotech Pty Ltd. | Production of proteins in active forms |
| US4981799A (en) * | 1987-08-21 | 1991-01-01 | Takeda Chemical Industries, Ltd. | Acylamino acid racemase, production and use thereof |
| US4765903A (en) * | 1987-10-06 | 1988-08-23 | Interferon Sciences, Inc. | Purification of monomeric interferon |
| US5159063A (en) * | 1989-02-02 | 1992-10-27 | The United States Of America As Represented By The Department Of Health And Human Services | Isolation and characterization of a 120 kda glycoprotein plasma |
| US5030352A (en) * | 1990-01-25 | 1991-07-09 | Purdue Research Foundation | Coated media for chromatography |
-
1992
- 1992-03-24 US US07/857,022 patent/US5252216A/en not_active Expired - Lifetime
-
1993
- 1993-03-22 ZA ZA932015A patent/ZA932015B/xx unknown
- 1993-03-24 ES ES93908538T patent/ES2149206T3/es not_active Expired - Lifetime
- 1993-03-24 MX MX9301655A patent/MX9301655A/es unknown
- 1993-03-24 KR KR1019940703342A patent/KR100241172B1/ko not_active IP Right Cessation
- 1993-03-24 DK DK93908538T patent/DK0643608T3/da active
- 1993-03-24 DE DE69328864T patent/DE69328864T2/de not_active Expired - Fee Related
- 1993-03-24 WO PCT/US1993/002732 patent/WO1993018835A1/fr active IP Right Grant
- 1993-03-24 AT AT93908538T patent/ATE193839T1/de not_active IP Right Cessation
- 1993-03-24 AU AU39324/93A patent/AU659936B2/en not_active Ceased
- 1993-03-24 EP EP93908538A patent/EP0643608B1/fr not_active Expired - Lifetime
- 1993-03-24 PT PT93908538T patent/PT643608E/pt unknown
- 1993-03-24 NZ NZ251601A patent/NZ251601A/en not_active IP Right Cessation
- 1993-03-24 CA CA002132533A patent/CA2132533C/fr not_active Expired - Fee Related
- 1993-03-24 JP JP51681493A patent/JP3335629B2/ja not_active Expired - Fee Related
- 1993-07-27 TW TW082105986A patent/TW321651B/zh active
-
1994
- 1994-09-23 FI FI944412A patent/FI109202B/fi not_active IP Right Cessation
- 1994-09-23 NO NO19943546A patent/NO310855B1/no unknown
-
2000
- 2000-09-06 GR GR20000402020T patent/GR3034332T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0643608A4 (fr) | 1997-11-26 |
| DK0643608T3 (da) | 2000-10-02 |
| EP0643608A1 (fr) | 1995-03-22 |
| GR3034332T3 (en) | 2000-12-29 |
| TW321651B (fr) | 1997-12-01 |
| AU659936B2 (en) | 1995-06-01 |
| DE69328864D1 (de) | 2000-07-20 |
| CA2132533A1 (fr) | 1993-09-30 |
| KR100241172B1 (ko) | 2000-02-01 |
| ES2149206T3 (es) | 2000-11-01 |
| ATE193839T1 (de) | 2000-06-15 |
| NO943546L (no) | 1994-11-23 |
| US5252216A (en) | 1993-10-12 |
| PT643608E (pt) | 2000-11-30 |
| ZA932015B (en) | 1994-09-21 |
| NZ251601A (en) | 1997-03-24 |
| JP3335629B2 (ja) | 2002-10-21 |
| DE69328864T2 (de) | 2000-12-14 |
| NO943546D0 (no) | 1994-09-23 |
| FI944412A (fi) | 1994-09-23 |
| EP0643608B1 (fr) | 2000-06-14 |
| AU3932493A (en) | 1993-10-21 |
| CA2132533C (fr) | 2004-01-13 |
| FI944412A0 (fi) | 1994-09-23 |
| KR950700779A (ko) | 1995-02-20 |
| WO1993018835A1 (fr) | 1993-09-30 |
| JPH07505469A (ja) | 1995-06-15 |
| FI109202B (fi) | 2002-06-14 |
| MX9301655A (es) | 1994-03-31 |
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