NO310057B1 - Anvendelse av visse metanbisfosfonsyrederivater for å forhindre lösning av protese og protesemigrering - Google Patents
Anvendelse av visse metanbisfosfonsyrederivater for å forhindre lösning av protese og protesemigrering Download PDFInfo
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- NO310057B1 NO310057B1 NO964486A NO964486A NO310057B1 NO 310057 B1 NO310057 B1 NO 310057B1 NO 964486 A NO964486 A NO 964486A NO 964486 A NO964486 A NO 964486A NO 310057 B1 NO310057 B1 NO 310057B1
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- Prior art keywords
- prosthesis
- acid derivatives
- bone
- migration
- administration
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- 210000002784 stomach Anatomy 0.000 description 1
- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- IWVCMVBTMGNXQD-UHFFFAOYSA-N terramycin dehydrate Natural products C1=CC=C2C(O)(C)C3C(O)C4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O IWVCMVBTMGNXQD-UHFFFAOYSA-N 0.000 description 1
- 238000004154 testing of material Methods 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 238000011541 total hip replacement Methods 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- 230000037317 transdermal delivery Effects 0.000 description 1
- 229940100640 transdermal system Drugs 0.000 description 1
- 229940078499 tricalcium phosphate Drugs 0.000 description 1
- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
- 239000001069 triethyl citrate Substances 0.000 description 1
- VMYFZRTXGLUXMZ-UHFFFAOYSA-N triethyl citrate Natural products CCOC(=O)C(O)(C(=O)OCC)C(=O)OCC VMYFZRTXGLUXMZ-UHFFFAOYSA-N 0.000 description 1
- 235000013769 triethyl citrate Nutrition 0.000 description 1
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 description 1
- 229940038773 trisodium citrate Drugs 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000000080 wetting agent Substances 0.000 description 1
- 229940100445 wheat starch Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Chemical Treatment Of Metals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9408775A GB9408775D0 (en) | 1994-05-04 | 1994-05-04 | Use of certain methanebisphosphonic acid derivatives to prevent prothesis loosening and prothesis migration |
| PCT/IB1995/000288 WO1995030421A1 (en) | 1994-05-04 | 1995-04-24 | Use of certain methanebisphosphonic acid derivatives to prevent prosthesis loosening and prosthesis migration |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO964486L NO964486L (no) | 1996-10-22 |
| NO964486D0 NO964486D0 (no) | 1996-10-22 |
| NO310057B1 true NO310057B1 (no) | 2001-05-14 |
Family
ID=10754497
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO964486A NO310057B1 (no) | 1994-05-04 | 1996-10-22 | Anvendelse av visse metanbisfosfonsyrederivater for å forhindre lösning av protese og protesemigrering |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5965547A (sv) |
| EP (1) | EP0758241B1 (sv) |
| JP (1) | JPH09512816A (sv) |
| AT (1) | ATE218350T1 (sv) |
| AU (1) | AU693541B2 (sv) |
| DE (1) | DE69526937T2 (sv) |
| DK (1) | DK0758241T3 (sv) |
| ES (1) | ES2177642T3 (sv) |
| FI (1) | FI118590B (sv) |
| GB (1) | GB9408775D0 (sv) |
| HU (1) | HUT74984A (sv) |
| IL (1) | IL113566A (sv) |
| NO (1) | NO310057B1 (sv) |
| NZ (1) | NZ283430A (sv) |
| PT (1) | PT758241E (sv) |
| TW (1) | TW458779B (sv) |
| WO (1) | WO1995030421A1 (sv) |
| ZA (1) | ZA953537B (sv) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5646134A (en) * | 1994-04-21 | 1997-07-08 | Merck & Co., Inc. | Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices |
| US6117856A (en) * | 1996-02-14 | 2000-09-12 | Binderman; Itzhak | Topical bisphosphonates for prevention of bone resorption |
| US6432932B1 (en) | 1997-07-22 | 2002-08-13 | Merck & Co., Inc. | Method for inhibiting bone resorption |
| US5994329A (en) * | 1997-07-22 | 1999-11-30 | Merck & Co., Inc. | Method for inhibiting bone resorption |
| GB2336311A (en) * | 1998-04-15 | 1999-10-20 | Merck & Co Inc | Bisphosphonate Dosing Regimen |
| US6137012A (en) | 1998-10-13 | 2000-10-24 | E. I. Du Pont De Nemours And Company | Phosphole and diphosphole ligands for catalysis |
| BR9915927A (pt) | 1998-12-04 | 2001-08-21 | Roche Diagnostics Gmbh | Uso de ácido ibandrÈnico ou seus sais ou ésteres fisiologicamente compatìveis |
| CA2360319A1 (en) * | 1999-02-09 | 2000-08-17 | Memorial Sloan-Kettering Cancer Center | Anti-resorptive bone cements and allogeneic, autografic, and xenografic bone grafts |
| EP1118328A1 (en) * | 1999-08-02 | 2001-07-25 | Toray Industries, Inc. | Insertion stabilizers for implants |
| AUPQ232599A0 (en) * | 1999-08-19 | 1999-09-09 | Royal Alexandra Hospital For Children, The | Drug for treating fractures |
| SI1591122T1 (sl) | 2000-06-20 | 2013-02-28 | Novartis Ag | Postopek za aplikacijo bisfosfonatov |
| NZ523086A (en) * | 2000-06-20 | 2007-07-27 | Novartis Ag | Method of administering bisphosphonates |
| AU2001287260A1 (en) * | 2000-07-12 | 2002-01-21 | Ecole Polytechnique Federale De Lausanne (Epfl) | Active biocoating for bone implant |
| GB0029111D0 (en) * | 2000-11-29 | 2001-01-10 | Novartis Ag | Organic compounds |
| CA2347330C (en) * | 2001-05-10 | 2002-03-12 | Pharmaceutical Partners Of Canada Inc. | Liquid injectable formulation of disodium pamidronate |
| JP2005522526A (ja) * | 2002-05-10 | 2005-07-28 | エフ．ホフマン−ラ ロシュ アーゲー | 骨粗鬆症の治療および予防用のビスホスホン酸 |
| ES2376425T3 (es) * | 2002-09-16 | 2012-03-13 | Novartis Ag | �?cido zoledrónico para prevenir o reducir fracturas secundarias tras fractura de cadera. |
| US20040138180A1 (en) * | 2002-10-03 | 2004-07-15 | Barr Laboratories, Inc. | Bisphosphonate composition and process for the preparation thereof |
| US8071574B2 (en) * | 2005-02-22 | 2011-12-06 | John Dennis Bobyn | Implant improving local bone formation |
| CA2669488A1 (en) * | 2006-11-17 | 2008-05-22 | Besins Healthcare | Pharmaceutical compositions comprising a bisphosphonate compound |
| EP1958649A1 (en) * | 2007-02-14 | 2008-08-20 | Graftys | Injectable calcium-phosphate cement releasing a bone resorption inhibitor |
| EP2136814A4 (en) * | 2007-03-21 | 2012-05-30 | Univ Duke | MEDICAL KITS AND FORMULATIONS FOR PREVENTING, TREATING OR REDUCING SECONDARY FRACTURES FROM A PREVIOUS FRACTURE |
| WO2008152518A2 (en) * | 2007-05-16 | 2008-12-18 | Actavis Group Ptc Ehf | Process for the preparation of risedronic acid or risedronate sodium |
| US9867838B2 (en) | 2009-09-01 | 2018-01-16 | Duke University | Methods for treating heart failure using bisphosphonate compositions |
| US8882740B2 (en) * | 2009-12-23 | 2014-11-11 | Stryker Trauma Gmbh | Method of delivering a biphosphonate and/or strontium ranelate below the surface of a bone |
| CN104010647A (zh) | 2011-11-16 | 2014-08-27 | 杜克大学 | 用于治疗和/或减轻心功能障碍的双膦酸盐组合物及方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2405254C2 (de) * | 1974-02-04 | 1982-05-27 | Henkel KGaA, 4000 Düsseldorf | Verwendung von 3-Amino-1-Hydroxypropan-1, 1-diphosphonsäure oder ihrer wasserlöslichen Salze bei der Beeinflußung von Calciumstoffwechselstörungen im menschlichen oder tierischen Körper |
| US4639338A (en) * | 1984-08-06 | 1987-01-27 | Ciba-Geigy Corporation | Preparation of crystalline disodium 3-amino-1-hydroxypropane-1,1-diphosphonate pentahydrate |
| ES2038692T4 (es) * | 1986-11-21 | 2012-02-10 | Novartis Ag | Procedimiento para la obtencion de acidos alcanodifosfonicos substituidos. |
| JPH05163150A (ja) * | 1991-05-13 | 1993-06-29 | E R Squibb & Sons Inc | アテローム性動脈硬化症の抑制・治療剤 |
| US5403829A (en) * | 1993-03-24 | 1995-04-04 | Leiras Oy | Use of bisphosphonates in endo-osteal bone surgery |
| US5646134A (en) * | 1994-04-21 | 1997-07-08 | Merck & Co., Inc. | Alendronate therapy to prevent loosening of, or pain associated with, orthopedic implant devices |
-
1994
- 1994-05-04 GB GB9408775A patent/GB9408775D0/en active Pending
-
1995
- 1995-04-24 US US08/732,324 patent/US5965547A/en not_active Expired - Fee Related
- 1995-04-24 AU AU21466/95A patent/AU693541B2/en not_active Ceased
- 1995-04-24 DE DE69526937T patent/DE69526937T2/de not_active Expired - Fee Related
- 1995-04-24 JP JP7528805A patent/JPH09512816A/ja active Pending
- 1995-04-24 AT AT95914495T patent/ATE218350T1/de not_active IP Right Cessation
- 1995-04-24 ES ES95914495T patent/ES2177642T3/es not_active Expired - Lifetime
- 1995-04-24 PT PT95914495T patent/PT758241E/pt unknown
- 1995-04-24 HU HU9603042A patent/HUT74984A/hu unknown
- 1995-04-24 EP EP95914495A patent/EP0758241B1/en not_active Expired - Lifetime
- 1995-04-24 NZ NZ283430A patent/NZ283430A/en not_active IP Right Cessation
- 1995-04-24 DK DK95914495T patent/DK0758241T3/da active
- 1995-04-24 WO PCT/IB1995/000288 patent/WO1995030421A1/en active IP Right Grant
- 1995-05-01 TW TW084104352A patent/TW458779B/zh not_active IP Right Cessation
- 1995-05-01 IL IL11356695A patent/IL113566A/en not_active IP Right Cessation
- 1995-05-03 ZA ZA953537A patent/ZA953537B/xx unknown
-
1996
- 1996-10-22 NO NO964486A patent/NO310057B1/no not_active IP Right Cessation
- 1996-10-28 FI FI964332A patent/FI118590B/sv active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| HUT74984A (en) | 1997-03-28 |
| EP0758241B1 (en) | 2002-06-05 |
| ZA953537B (en) | 1995-11-06 |
| DE69526937T2 (de) | 2003-01-02 |
| NO964486L (no) | 1996-10-22 |
| US5965547A (en) | 1999-10-12 |
| TW458779B (en) | 2001-10-11 |
| FI964332A0 (sv) | 1996-10-28 |
| NO964486D0 (no) | 1996-10-22 |
| FI118590B (sv) | 2008-01-15 |
| IL113566A0 (en) | 1995-08-31 |
| ATE218350T1 (de) | 2002-06-15 |
| DK0758241T3 (da) | 2002-09-23 |
| AU693541B2 (en) | 1998-07-02 |
| GB9408775D0 (en) | 1994-06-22 |
| HU9603042D0 (en) | 1997-01-28 |
| FI964332A (sv) | 1996-10-28 |
| NZ283430A (en) | 2000-06-23 |
| JPH09512816A (ja) | 1997-12-22 |
| WO1995030421A1 (en) | 1995-11-16 |
| AU2146695A (en) | 1995-11-29 |
| EP0758241A1 (en) | 1997-02-19 |
| PT758241E (pt) | 2002-10-31 |
| DE69526937D1 (de) | 2002-07-11 |
| IL113566A (en) | 2002-05-23 |
| ES2177642T3 (es) | 2002-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |