NO307519B1 - Materiale med acyl-CoA-kolesterol-acyltransferase-inhiberende aktivitet, samt fremstilling derav - Google Patents

Materiale med acyl-CoA-kolesterol-acyltransferase-inhiberende aktivitet, samt fremstilling derav

Info

Publication number
NO307519B1
NO307519B1 NO942634A NO942634A NO307519B1 NO 307519 B1 NO307519 B1 NO 307519B1 NO 942634 A NO942634 A NO 942634A NO 942634 A NO942634 A NO 942634A NO 307519 B1 NO307519 B1 NO 307519B1
Authority
NO
Norway
Prior art keywords
acyl
hydrogen
coa
cholesterol
preparation
Prior art date
Application number
NO942634A
Other languages
English (en)
Other versions
NO942634D0 (no
NO942634L (no
Inventor
Satoshi Omura
Hiroshi Tomoda
Rokuro Masuma
Original Assignee
Kitasato Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kitasato Inst filed Critical Kitasato Inst
Publication of NO942634D0 publication Critical patent/NO942634D0/no
Publication of NO942634L publication Critical patent/NO942634L/no
Publication of NO307519B1 publication Critical patent/NO307519B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/145Fungal isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/645Fungi ; Processes using fungi
    • C12R2001/66Aspergillus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi
    • Y10S435/913Aspergillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Mechanical Coupling Of Light Guides (AREA)
  • Wire Bonding (AREA)
NO942634A 1992-10-22 1994-07-13 Materiale med acyl-CoA-kolesterol-acyltransferase-inhiberende aktivitet, samt fremstilling derav NO307519B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP28475992 1992-10-22
JP03526193A JP3233476B2 (ja) 1992-10-22 1993-02-24 Fo−1289物質およびその製造法
PCT/JP1993/000367 WO1994009147A1 (en) 1992-10-22 1993-03-26 Fo-1289 substance and its production

Publications (3)

Publication Number Publication Date
NO942634D0 NO942634D0 (no) 1994-07-13
NO942634L NO942634L (no) 1995-04-21
NO307519B1 true NO307519B1 (no) 2000-04-17

Family

ID=26374213

Family Applications (1)

Application Number Title Priority Date Filing Date
NO942634A NO307519B1 (no) 1992-10-22 1994-07-13 Materiale med acyl-CoA-kolesterol-acyltransferase-inhiberende aktivitet, samt fremstilling derav

Country Status (15)

Country Link
US (1) US5807721A (no)
EP (1) EP0667914B1 (no)
JP (1) JP3233476B2 (no)
KR (1) KR100323572B1 (no)
AT (1) ATE168722T1 (no)
AU (1) AU664437B2 (no)
CA (1) CA2127878C (no)
DE (1) DE69319920T2 (no)
DK (1) DK0667914T3 (no)
ES (1) ES2119894T3 (no)
FI (1) FI103670B (no)
HU (1) HU218015B (no)
NO (1) NO307519B1 (no)
NZ (1) NZ249975A (no)
WO (1) WO1994009147A1 (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5037164B2 (ja) * 2005-06-01 2012-09-26 Meiji Seikaファルマ株式会社 害虫防除剤
US7491738B2 (en) 2005-06-01 2009-02-17 Meiji Seika Kaisha, Ltd. Pest control agents
TWI388282B (zh) * 2005-06-01 2013-03-11 Meiji Seika Pharma Co Ltd 害蟲控制劑
KR101486094B1 (ko) 2007-03-08 2015-01-28 메이지 세이카 파루마 가부시키가이샤 유해생물 방제용 조성물
EP2592084B8 (en) 2007-08-13 2014-08-27 Basf Se Process for producing pyripyropene derivatives and intermediates for the production thereof.
CN101902916B (zh) 2007-12-21 2014-04-16 明治制果药业株式会社 新型内吸性杀虫剂
US8519128B2 (en) * 2007-12-25 2013-08-27 The Kitasato Institute Pyripyropene derivatives having an ACAT2-inhibiting activity
US8557550B2 (en) 2008-07-24 2013-10-15 Meija Seika Pharma Co., Ltd. Pyripyropene a biosynthetic gene
MX2011011414A (es) 2009-05-13 2011-12-06 Meiji Seika Pharma Co Ltd Proceso para producir derivados de piripiropeno.
BR112012019456B8 (pt) 2010-01-26 2022-08-02 Mmag Co Ltd Plasmídio compreendendo um ou mais polinucleotídeos e um promotor que é heterólogo para o um ou mais polinucleotídeos
CA2787829A1 (en) * 2010-01-26 2011-08-04 Meiji Seika Pharma Co., Ltd. Method for producing pyripyropene derivatives by the enzymatic method
WO2011093186A1 (ja) 2010-01-26 2011-08-04 明治製菓株式会社 ピリピロペン生合成遺伝子群およびマーカー遺伝子を含む核酸構築物
UA111151C2 (uk) 2010-03-01 2016-04-11 Мейдзі Сейка Фарма Ко., Лтд. Спосіб одержання похідних пірипіропену
EP2578084A4 (en) * 2010-05-24 2014-04-23 Meiji Seika Pharma Co Ltd MEANS OF COMBATING HARMFUL ORGANISMS
PE20131355A1 (es) 2010-09-14 2013-12-06 Basf Se Composicion que contiene un insecticida de piripiropeno y un adyuvante
WO2012035010A1 (en) 2010-09-14 2012-03-22 Basf Se Composition containing a pyripyropene insecticide and a base
CN104168769B (zh) 2012-03-12 2016-12-14 巴斯夫欧洲公司 生产啶南平杀虫剂的含水悬浮液浓缩物配制剂的方法
WO2013135605A1 (en) 2012-03-12 2013-09-19 Basf Se Liquid concentrate formulation containing a pyripyropene insecticide ii
ES2566911T3 (es) 2012-03-12 2016-04-18 Basf Se Formulación de concentrado líquido que contiene un insecticida de piripiropeno I
CN102936252B (zh) * 2012-10-22 2015-03-04 中山大学 一类二倍半萜类化合物及其制备方法与应用
WO2014155214A1 (en) * 2013-03-28 2014-10-02 Basf Se Production of pyripyropenes from dry biomass
CN103910746B (zh) * 2014-02-28 2016-08-03 中山大学 一类海洋真菌来源的Berkeleyones化合物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4231938A (en) * 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
US5250935A (en) * 1990-09-24 1993-10-05 Snap-On Tools Corporation Waveform peak capture circuit for digital engine analyzer
US5151365A (en) * 1991-03-18 1992-09-29 Merck & Co., Inc. Culture of Asperigillus versicolor and mutants thereof
JP2993767B2 (ja) * 1991-06-06 1999-12-27 社団法人北里研究所 Fo−1289a物質およびその製造法

Also Published As

Publication number Publication date
ATE168722T1 (de) 1998-08-15
HU218015B (hu) 2000-05-28
AU3767993A (en) 1994-05-09
WO1994009147A1 (en) 1994-04-28
NO942634D0 (no) 1994-07-13
CA2127878C (en) 1997-07-08
EP0667914A1 (en) 1995-08-23
EP0667914B1 (en) 1998-07-22
JPH06184158A (ja) 1994-07-05
HUT69789A (en) 1995-09-28
FI103670B1 (fi) 1999-08-13
JP3233476B2 (ja) 2001-11-26
KR100323572B1 (ko) 2002-09-04
AU664437B2 (en) 1995-11-16
CA2127878A1 (en) 1994-04-28
HU9402127D0 (en) 1994-09-28
FI943383A (fi) 1994-08-31
NO942634L (no) 1995-04-21
ES2119894T3 (es) 1998-10-16
DK0667914T3 (da) 1998-11-02
DE69319920T2 (de) 1998-12-10
NZ249975A (en) 1996-06-25
KR950701976A (ko) 1995-05-17
FI103670B (fi) 1999-08-13
FI943383A0 (fi) 1994-07-15
DE69319920D1 (de) 1998-08-27
US5807721A (en) 1998-09-15

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