NO307175B1 - O-Acyl-4-fenyl-cykloalkanoler, deres salter, legemidler som inneholder disse forbindelser og deres anvendelse - Google Patents

O-Acyl-4-fenyl-cykloalkanoler, deres salter, legemidler som inneholder disse forbindelser og deres anvendelse

Info

Publication number
NO307175B1
NO307175B1 NO964525A NO964525A NO307175B1 NO 307175 B1 NO307175 B1 NO 307175B1 NO 964525 A NO964525 A NO 964525A NO 964525 A NO964525 A NO 964525A NO 307175 B1 NO307175 B1 NO 307175B1
Authority
NO
Norway
Prior art keywords
denotes
pct
phenyl
acyl
alkynyl
Prior art date
Application number
NO964525A
Other languages
English (en)
Norwegian (no)
Other versions
NO964525L (no
NO964525D0 (no
Inventor
Eberhard Woitun
Roland Maier
Peter Mueller
Rudolf Hurnaus
Michael Mark
Bernhard Eisele
Ralph-Michael Budzinski
Gerhard Hallermayer
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Priority to NO964525A priority Critical patent/NO307175B1/no
Publication of NO964525L publication Critical patent/NO964525L/no
Publication of NO964525D0 publication Critical patent/NO964525D0/no
Publication of NO307175B1 publication Critical patent/NO307175B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/24—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Reproductive Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fats And Perfumes (AREA)
NO964525A 1992-11-20 1996-10-24 O-Acyl-4-fenyl-cykloalkanoler, deres salter, legemidler som inneholder disse forbindelser og deres anvendelse NO307175B1 (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO964525A NO307175B1 (no) 1992-11-20 1996-10-24 O-Acyl-4-fenyl-cykloalkanoler, deres salter, legemidler som inneholder disse forbindelser og deres anvendelse

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4239150A DE4239150A1 (de) 1992-11-20 1992-11-20 O-Acyl-4-phenyl-cyclohexanole, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
BR9408573A BR9408573A (pt) 1992-11-20 1994-04-25 O-acil-4-fenil-ciclohexanóis seus sais medicamentos contendo estes compostos e seu uso bem como para sua preparação
PCT/EP1994/001276 WO1995029148A1 (de) 1992-11-20 1994-04-25 O-acyl-4-phenyl-cyclohexanole, deren salze, diese verbindungen enthaltende arzneimittel und deren verwendung sowie verfahren zu ihrer herstellung
NO964525A NO307175B1 (no) 1992-11-20 1996-10-24 O-Acyl-4-fenyl-cykloalkanoler, deres salter, legemidler som inneholder disse forbindelser og deres anvendelse

Publications (3)

Publication Number Publication Date
NO964525L NO964525L (no) 1996-10-24
NO964525D0 NO964525D0 (no) 1996-10-24
NO307175B1 true NO307175B1 (no) 2000-02-21

Family

ID=27160120

Family Applications (1)

Application Number Title Priority Date Filing Date
NO964525A NO307175B1 (no) 1992-11-20 1996-10-24 O-Acyl-4-fenyl-cykloalkanoler, deres salter, legemidler som inneholder disse forbindelser og deres anvendelse

Country Status (17)

Country Link
US (1) US5726205A (fi)
EP (1) EP0757669B1 (fi)
JP (1) JPH09512255A (fi)
AT (1) ATE173460T1 (fi)
BG (1) BG62961B1 (fi)
BR (1) BR9408573A (fi)
DE (2) DE4239150A1 (fi)
DK (1) DK0757669T3 (fi)
ES (1) ES2126759T3 (fi)
FI (1) FI964277A0 (fi)
LV (1) LV11832B (fi)
NO (1) NO307175B1 (fi)
NZ (1) NZ266138A (fi)
PL (1) PL179890B1 (fi)
RU (1) RU2130921C1 (fi)
SK (1) SK281213B6 (fi)
WO (1) WO1995029148A1 (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4239150A1 (de) * 1992-11-20 1994-05-26 Thomae Gmbh Dr K O-Acyl-4-phenyl-cyclohexanole, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
DE19626771C2 (de) * 1996-07-03 1998-09-24 Merck Patent Gmbh 4-(4-Oxocyclohexyl)-benzamide
FR2754255B1 (fr) * 1996-10-08 1998-10-30 Synthelabo Procede de preparation de derives de trans-4-(4- aminomethylphenyl) cyclohexanols
DE19704401C1 (de) * 1997-02-06 1998-05-07 Thomae Gmbh Dr K Verfahren zur Herstellung von trans-4-(4-Aminomethyl)phenyl-cyclohexanolen
DE19754795A1 (de) * 1997-12-10 1999-06-17 Boehringer Ingelheim Pharma Neue Urethane, ihre Thio- und Dithioanaloga, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
EP1485077A4 (en) * 2002-03-12 2007-07-18 Merck & Co Inc DRUGS COMBINATION THERAPY
CN101945848A (zh) 2007-12-20 2011-01-12 英维沃医药有限公司 四取代的苯
RU2662564C2 (ru) 2012-07-04 2018-07-26 ЗЗ Байотек ЛЛС Лечение воспалительных заболеваний кожи
WO2015157791A1 (en) 2014-04-16 2015-10-22 The University Of Sydney Treatment of abnormal cutaneous scarring

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431564A (en) * 1981-05-01 1984-02-14 Chisso Corporation Liquid-crystalline biphenyl or terphenyl derivatives
US5391571A (en) * 1989-11-15 1995-02-21 American Home Products Corporation Cholesterol ester hydrolase inhibitors
CA2044533A1 (en) * 1990-06-29 1991-12-30 Philippe Guerry Substituted aminoalkylbiphenyl derivatives
DE4239151A1 (de) * 1992-11-20 1994-05-26 Thomae Gmbh Dr K N,N-Disubstituierte Arylcycloalkylamine, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung
DE4239150A1 (de) * 1992-11-20 1994-05-26 Thomae Gmbh Dr K O-Acyl-4-phenyl-cyclohexanole, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung

Also Published As

Publication number Publication date
FI964277A (fi) 1996-10-24
LV11832A (lv) 1997-08-20
WO1995029148A1 (de) 1995-11-02
BG100912A (en) 1997-07-31
BG62961B1 (bg) 2000-12-29
DE4239150A1 (de) 1994-05-26
PL179890B1 (pl) 2000-11-30
EP0757669B1 (de) 1998-11-18
SK135996A3 (en) 1997-05-07
DE59407317D1 (de) 1998-12-24
US5726205A (en) 1998-03-10
ATE173460T1 (de) 1998-12-15
BR9408573A (pt) 1997-08-26
AU685118B2 (en) 1998-01-15
SK281213B6 (sk) 2001-01-18
EP0757669A1 (de) 1997-02-12
RU2130921C1 (ru) 1999-05-27
NO964525L (no) 1996-10-24
AU6721194A (en) 1995-11-16
ES2126759T3 (es) 1999-04-01
JPH09512255A (ja) 1997-12-09
LV11832B (en) 1997-12-20
FI964277A0 (fi) 1996-10-24
DK0757669T3 (da) 1999-08-02
NZ266138A (en) 1998-03-25
NO964525D0 (no) 1996-10-24
PL316964A1 (en) 1997-03-03

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Legal Events

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Free format text: LAPSED IN OCTOBER 2003