NO305861B1 - N-acylsulfaminsyre-estere -tioestere, N-acylsulfonamider og N-sulfonyl-karbaminsyre-estere, -tioestere og farmas°ytisk preparat inneholdende disse forbindelsene - Google Patents
N-acylsulfaminsyre-estere -tioestere, N-acylsulfonamider og N-sulfonyl-karbaminsyre-estere, -tioestere og farmas°ytisk preparat inneholdende disse forbindelseneInfo
- Publication number
- NO305861B1 NO305861B1 NO954564A NO954564A NO305861B1 NO 305861 B1 NO305861 B1 NO 305861B1 NO 954564 A NO954564 A NO 954564A NO 954564 A NO954564 A NO 954564A NO 305861 B1 NO305861 B1 NO 305861B1
- Authority
- NO
- Norway
- Prior art keywords
- thioesters
- acid esters
- compounds
- acylsulfamic
- acylsulfonamides
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- -1 esters thioesters Chemical class 0.000 title 1
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- WZHRJGWXUCLILI-UHFFFAOYSA-N sulfonylcarbamic acid Chemical class OC(=O)N=S(=O)=O WZHRJGWXUCLILI-UHFFFAOYSA-N 0.000 title 1
- 150000007970 thio esters Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 125000001624 naphthyl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000005073 adamantyl group Chemical group C12(CC3CC(CC(C1)C3)C2)* 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C307/02—Monoamides of sulfuric acids or esters thereof, e.g. sulfamic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/51—Y being a hydrogen or a carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
- C07D311/82—Xanthenes
- C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6251593A | 1993-05-14 | 1993-05-14 | |
| US08/223,932 US5491172A (en) | 1993-05-14 | 1994-04-13 | N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents |
| PCT/US1994/005233 WO1994026702A1 (en) | 1993-05-14 | 1994-05-11 | N-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO954564D0 NO954564D0 (no) | 1995-11-13 |
| NO954564L NO954564L (no) | 1996-01-11 |
| NO305861B1 true NO305861B1 (no) | 1999-08-09 |
Family
ID=26742358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO954564A NO305861B1 (no) | 1993-05-14 | 1995-11-13 | N-acylsulfaminsyre-estere -tioestere, N-acylsulfonamider og N-sulfonyl-karbaminsyre-estere, -tioestere og farmas°ytisk preparat inneholdende disse forbindelsene |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US5633287A (no) |
| EP (1) | EP0698010B1 (no) |
| JP (1) | JP3704149B2 (no) |
| AT (1) | ATE178891T1 (no) |
| AU (1) | AU681152B2 (no) |
| CA (1) | CA2158268C (no) |
| CZ (1) | CZ290683B6 (no) |
| DE (1) | DE69417885T2 (no) |
| DK (1) | DK0698010T3 (no) |
| ES (1) | ES2133163T3 (no) |
| FI (1) | FI955438A (no) |
| GR (1) | GR3030356T3 (no) |
| HU (1) | HU223044B1 (no) |
| IL (1) | IL109431A (no) |
| NO (1) | NO305861B1 (no) |
| NZ (1) | NZ266689A (no) |
| PH (1) | PH30943A (no) |
| RU (1) | RU2137756C1 (no) |
| SG (1) | SG47056A1 (no) |
| SK (1) | SK282790B6 (no) |
| WO (1) | WO1994026702A1 (no) |
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| GEP20012511B (en) * | 1995-08-04 | 2001-08-27 | Warner Lambert Co | Method for Lowering Level of Lipoproteins (a) in Serum or Plasma of Mammals, Method for Treatment of Peripheral Vascular Diseases or Restenosis |
| ATE348607T1 (de) * | 1995-11-02 | 2007-01-15 | Warner Lambert Co | Verfahren und pharmazeutische zusammensetzung zur regelung der lipidkonzentration |
| US6093744A (en) * | 1997-04-21 | 2000-07-25 | Warner-Lambert Company | N-acyl sulfamic acid esters useful as hypocholesterolemic agents |
| IT1303249B1 (it) * | 1998-10-23 | 2000-11-06 | Dompe Spa | Alcune n-(2-aril-propionil)-solfonammidi e preparazionifarmaceutiche che le contengono. |
| EP1229907A1 (en) * | 1999-11-05 | 2002-08-14 | Warner-Lambert Company | Prevention of plaque rupture by acat inhibitors |
| DE10016544A1 (de) * | 2000-04-03 | 2001-10-11 | Bayer Ag | C2-phenylsubstituierte Ketoenole |
| DE10027887A1 (de) * | 2000-05-31 | 2001-12-13 | Jenapharm Gmbh | Verbindungen mit einer Sulfonamidgruppe und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen |
| IL155215A0 (en) | 2000-10-11 | 2003-11-23 | Esperion Therapeutics Inc | Ether compounds and compositions for cholesterol management and related uses |
| CN101426763A (zh) | 2000-10-11 | 2009-05-06 | 埃斯佩里安医疗公司 | 用于胆固醇治疗和相关应用的硫化物和二硫化物化合物和组合物 |
| US20040122091A1 (en) * | 2000-10-11 | 2004-06-24 | Esperion Therapeutics, Inc. | Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses |
| US7304093B2 (en) * | 2000-10-11 | 2007-12-04 | Esperion Therapeutics, Inc. | Ketone compounds and compositions for cholesterol management and related uses |
| BR0114623A (pt) | 2000-10-11 | 2005-12-13 | Esperion Therapeutics Inc | Composto, composição farmacêutica, métodos para tratar ou prevenir uma doença cardiovascular, uma dislipidemia, uma dislipoproteinemia, um distúrbio do metabolismo da glicose, trombótico e associado com o receptor ativado do proliferador de peroxissoma, a doença de alzheimer, a sìndrome x ou sìndrome metabólica, a septicemia, a obesidade, pancreatite, a hipertensão, doença renal, câncer, a inflamação e a impotência, em um paciente e para reduzir o teor de gordura da carne em animal de criação e de colesterol de ovos de aves domésticas |
| WO2002030860A2 (en) | 2000-10-11 | 2002-04-18 | Esperion Therapeutics, Inc. | Ketone compounds and compositions for cholesterol management and related uses |
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| EP1281399A3 (en) * | 2001-08-01 | 2004-02-11 | Warner-Lambert Company | Dual inhibitors of wax ester and cholesteryl ester synthesis for inhibiting sebum production |
| AR037097A1 (es) | 2001-10-05 | 2004-10-20 | Novartis Ag | Compuestos acilsulfonamidas, composiciones farmaceuticas y el uso de dichos compuestos para la preparacion de un medicamento |
| US20040204502A1 (en) * | 2001-10-11 | 2004-10-14 | Dasseux Jean-Louis Henri | Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses |
| US20050020694A1 (en) * | 2001-10-11 | 2005-01-27 | Dasseux Jean-Louis Henri | Sulfide and disulfide compounds and compositions for cholesterol management and related uses |
| US20040192771A1 (en) * | 2001-10-11 | 2004-09-30 | Dasseux Jean-Louis Henri | Ether compounds and compositions for cholesterol management and related uses |
| AU2003221926A1 (en) * | 2002-04-10 | 2003-10-27 | Esperion Therapeutics, Inc. | Mimics of acyl coenzyme-a comprising pantolactone and pantothenic acid derivatives, compositions thereof, and methods of cholesterol management and related uses |
| HUE036646T2 (hu) * | 2003-01-23 | 2018-07-30 | Esperion Therapeutics Inc | Hidroxilvegyületek és kompozícióik koleszterin szabályozására és kapcsolódó alkalmazásokra |
| EP1666038A4 (en) * | 2003-08-29 | 2010-10-20 | Kowa Co | METHOD FOR STABILIZING A LIPID-RICH PLATE AND METHOD FOR PREVENTING THE BREAKAGE OF THE PLATE |
| JP2007512359A (ja) | 2003-11-19 | 2007-05-17 | メタバシス・セラピューティクス・インコーポレイテッド | 新規なリン含有甲状腺ホルモン様物質 |
| JP2007525408A (ja) | 2003-12-24 | 2007-09-06 | エスペリオン セラピューティクス，インコーポレイテッド | コレステロール管理および関連使用のためのケトン化合物および組成物 |
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| AR058562A1 (es) | 2005-12-22 | 2008-02-13 | Astrazeneca Ab | Derivados de pirimido [4,5 b] (1,4) oxazinas , procedimientos de obtencion y su uso como inhibidores de acetil coa y dgat 1 |
| US8084478B2 (en) | 2006-05-30 | 2011-12-27 | Asstrazeneca Ab | Substituted 5- phenylamino- 1, 3, 4-oxadiazol-2-ylcarbonylamino-4-phenoxy-cyclohexane carboxylic acid as inhibitors of acetyl coenzyme A diacylglycerol acyltransferase |
| CA2651663A1 (en) | 2006-05-30 | 2007-12-06 | Astrazeneca Ab | Chemical compounds |
| KR20100099738A (ko) | 2007-12-20 | 2010-09-13 | 아스트라제네카 아베 | Ｄｇａｔ1 억제제로서의 카르바모일 화합물 190 |
| JP5291979B2 (ja) | 2008-04-24 | 2013-09-18 | 株式会社フジクラ | 圧力センサ及びその製造方法と、該圧力センサを備えた電子部品 |
| WO2010039801A2 (en) | 2008-10-02 | 2010-04-08 | The J. David Gladstone Institutes | Methods of treating hepatitis c virus infection |
| WO2010093601A1 (en) | 2009-02-10 | 2010-08-19 | Metabasis Therapeutics, Inc. | Novel sulfonic acid-containing thyromimetics, and methods for their use |
| MX2011014018A (es) | 2009-06-19 | 2012-02-22 | Astrazeneca Ab | Pirazincarboxamidas como inhibidores de dgati. |
| MX2017011499A (es) | 2015-03-13 | 2018-03-26 | Esperion Therapeutics Inc | Combinaciones de dosis fija y formulaciones que comprenden ácido 8-hidroxi-2,2,14,14 tetrametilpentadecanodioico (etc1002) y ezetimiba y métodos para tratar o reducir el riesgo de enfermedad cardiovascular. |
| MA41793A (fr) | 2015-03-16 | 2018-01-23 | Esperion Therapeutics Inc | Associations de doses fixes comprenant du etc1002 et une ou plusieurs statines permettant de traiter ou de réduire un risque cardiovasculaire |
| US10519085B2 (en) * | 2016-01-15 | 2019-12-31 | Bayer Cropscience Aktiengesellschaft | Process for preparing substituted 2-arylethanols |
| WO2019166628A1 (en) | 2018-03-02 | 2019-09-06 | Inflazome Limited | Novel compounds |
| US11834433B2 (en) | 2018-03-02 | 2023-12-05 | Inflazome Limited | Compounds |
| WO2019166632A1 (en) | 2018-03-02 | 2019-09-06 | Inflazome Limited | Novel compounds |
| US20200407340A1 (en) * | 2018-03-02 | 2020-12-31 | Inflazome Limited | Sulfonamide derivates as nlrp3 inhibitors |
| BR112021025964A2 (pt) | 2019-06-21 | 2022-05-24 | Esperion Therapeutics Inc | Formas de sal de ácido bempedoico e métodos para uso das mesmas |
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| US5250558A (en) * | 1992-01-28 | 1993-10-05 | Merck & Co., Inc. | Substituted triazolinones, triazolinethiones, and triazolinimines as neurotensin antagonists used to treat psychosis |
| GB2263639A (en) * | 1992-01-28 | 1993-08-04 | Merck & Co Inc | Substituted pyrimidinones as neurotensin antagonists |
| GB2263637A (en) * | 1992-01-28 | 1993-08-04 | Merck & Co Inc | Substituted imidazo-fused 6-membered carbocycle or heterocycle as neurotensin antagonists |
| US5491172A (en) * | 1993-05-14 | 1996-02-13 | Warner-Lambert Company | N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents |
-
1994
- 1994-04-26 IL IL10943194A patent/IL109431A/en not_active IP Right Cessation
- 1994-05-11 DK DK94916734T patent/DK0698010T3/da active
- 1994-05-11 CZ CZ19952966A patent/CZ290683B6/cs not_active IP Right Cessation
- 1994-05-11 EP EP94916734A patent/EP0698010B1/en not_active Expired - Lifetime
- 1994-05-11 SK SK1396-95A patent/SK282790B6/sk unknown
- 1994-05-11 SG SG1996004778A patent/SG47056A1/en unknown
- 1994-05-11 HU HU9502811A patent/HU223044B1/hu not_active IP Right Cessation
- 1994-05-11 PH PH48245A patent/PH30943A/en unknown
- 1994-05-11 AU AU68311/94A patent/AU681152B2/en not_active Ceased
- 1994-05-11 ES ES94916734T patent/ES2133163T3/es not_active Expired - Lifetime
- 1994-05-11 AT AT94916734T patent/ATE178891T1/de not_active IP Right Cessation
- 1994-05-11 NZ NZ266689A patent/NZ266689A/en not_active IP Right Cessation
- 1994-05-11 WO PCT/US1994/005233 patent/WO1994026702A1/en active IP Right Grant
- 1994-05-11 RU RU95122768A patent/RU2137756C1/ru not_active IP Right Cessation
- 1994-05-11 JP JP52567494A patent/JP3704149B2/ja not_active Expired - Fee Related
- 1994-05-11 CA CA002158268A patent/CA2158268C/en not_active Expired - Fee Related
- 1994-05-11 DE DE69417885T patent/DE69417885T2/de not_active Expired - Lifetime
-
1995
- 1995-10-23 US US08/546,967 patent/US5633287A/en not_active Expired - Lifetime
- 1995-11-10 FI FI955438A patent/FI955438A/fi unknown
- 1995-11-13 NO NO954564A patent/NO305861B1/no unknown
-
1999
- 1999-05-27 GR GR990401448T patent/GR3030356T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CZ296695A3 (en) | 1996-09-11 |
| DE69417885T2 (de) | 1999-09-30 |
| IL109431A0 (en) | 1994-07-31 |
| CZ290683B6 (cs) | 2002-09-11 |
| NZ266689A (en) | 1997-11-24 |
| ES2133163T3 (es) | 1999-09-01 |
| FI955438A0 (fi) | 1995-11-10 |
| SK139695A3 (en) | 1996-11-06 |
| CA2158268C (en) | 2006-11-07 |
| AU681152B2 (en) | 1997-08-21 |
| DK0698010T3 (da) | 1999-10-25 |
| IL109431A (en) | 2001-01-11 |
| CA2158268A1 (en) | 1994-11-24 |
| JPH08510256A (ja) | 1996-10-29 |
| GR3030356T3 (en) | 1999-09-30 |
| HU223044B1 (hu) | 2004-03-01 |
| AU6831194A (en) | 1994-12-12 |
| SK282790B6 (sk) | 2002-12-03 |
| WO1994026702A1 (en) | 1994-11-24 |
| EP0698010A1 (en) | 1996-02-28 |
| HUT72653A (en) | 1996-05-28 |
| NO954564L (no) | 1996-01-11 |
| US5633287A (en) | 1997-05-27 |
| RU2137756C1 (ru) | 1999-09-20 |
| SG47056A1 (en) | 1998-03-20 |
| PH30943A (en) | 1997-12-23 |
| ATE178891T1 (de) | 1999-04-15 |
| HU9502811D0 (en) | 1995-11-28 |
| JP3704149B2 (ja) | 2005-10-05 |
| NO954564D0 (no) | 1995-11-13 |
| EP0698010B1 (en) | 1999-04-14 |
| FI955438A (fi) | 1995-11-10 |
| DE69417885D1 (de) | 1999-05-20 |
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