NO301163B1 - 5-Acylamino-1,2,4-tiadiazoler, og farmasöytiske blandinger inneholdende dem - Google Patents

5-Acylamino-1,2,4-tiadiazoler, og farmasöytiske blandinger inneholdende dem Download PDF

Info

Publication number
NO301163B1
NO301163B1 NO941374A NO941374A NO301163B1 NO 301163 B1 NO301163 B1 NO 301163B1 NO 941374 A NO941374 A NO 941374A NO 941374 A NO941374 A NO 941374A NO 301163 B1 NO301163 B1 NO 301163B1
Authority
NO
Norway
Prior art keywords
group
alkyl
formula
compounds
nitrogen
Prior art date
Application number
NO941374A
Other languages
English (en)
Norwegian (no)
Other versions
NO941374D0 (no
NO941374L (no
Inventor
Daniel Frehel
Daniele Gully
Robert Boigegrain
Alain Badorc
Jean-Pierre Bras
Pierre Despeyroux
Original Assignee
Sanofi Elf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Elf filed Critical Sanofi Elf
Publication of NO941374D0 publication Critical patent/NO941374D0/no
Publication of NO941374L publication Critical patent/NO941374L/no
Publication of NO301163B1 publication Critical patent/NO301163B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/081,2,4-Thiadiazoles; Hydrogenated 1,2,4-thiadiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06Peri-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO941374A 1993-04-16 1994-04-15 5-Acylamino-1,2,4-tiadiazoler, og farmasöytiske blandinger inneholdende dem NO301163B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9304535A FR2703995B1 (fr) 1993-04-16 1993-04-16 5-acylamino 1,2,4-thiadiazoles, leur preparation et compositions pharmaceutiques en contenant.

Publications (3)

Publication Number Publication Date
NO941374D0 NO941374D0 (no) 1994-04-15
NO941374L NO941374L (no) 1994-10-17
NO301163B1 true NO301163B1 (no) 1997-09-22

Family

ID=9446163

Family Applications (1)

Application Number Title Priority Date Filing Date
NO941374A NO301163B1 (no) 1993-04-16 1994-04-15 5-Acylamino-1,2,4-tiadiazoler, og farmasöytiske blandinger inneholdende dem

Country Status (15)

Country Link
US (1) US5534530A (xx)
EP (1) EP0620221A1 (xx)
JP (1) JP3029372B2 (xx)
CN (1) CN1050128C (xx)
AU (1) AU678208B2 (xx)
CA (1) CA2121425A1 (xx)
FI (1) FI941776A (xx)
FR (1) FR2703995B1 (xx)
HU (1) HU217549B (xx)
IL (1) IL109275A (xx)
NO (1) NO301163B1 (xx)
NZ (1) NZ260313A (xx)
RU (1) RU2129550C1 (xx)
TW (1) TW295584B (xx)
ZA (1) ZA942577B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE68593B1 (en) * 1989-12-06 1996-06-26 Sanofi Sa Heterocyclic substituted acylaminothiazoles their preparation and pharmaceutical compositions containing them
WO1997014681A1 (en) * 1995-10-16 1997-04-24 Fujisawa Pharmaceutical Co., Ltd. Heterocyclic compounds as h+-atpases
NZ314105A (en) * 1996-02-02 1997-12-19 Sumitomo Pharma Guanidine derivative substituted with a substituted indole which is peri condensed with a heterocyclic ring
WO1998035707A1 (en) 1997-02-18 1998-08-20 Thomas Jefferson University Compositions that bind to pancreatic cancer cells and methods of using the same
FR2763337B1 (fr) * 1997-05-13 1999-08-20 Sanofi Sa Nouveaux derives du triazole, un procede pour leur preparation et compositions pharmaceutiques les contenant
US6768024B1 (en) 2000-08-04 2004-07-27 Lion Bioscience Ag Triamine derivative melanocortin receptor ligands and methods of using same
EP1335914A1 (en) * 2000-10-26 2003-08-20 Sanofi-Synthelabo Triazole derivatives and pharmaceutical compositions comprising them
FR2815963B1 (fr) * 2000-10-26 2003-02-28 Sanofi Synthelabo Nouveaux derives du triazole et les compositions pharmaceutiques les contenant
EP1314733A1 (en) * 2001-11-22 2003-05-28 Aventis Pharma Deutschland GmbH Indole-2-carboxamides as factor Xa inhibitors
NZ542491A (en) 2003-03-28 2009-04-30 Janssen Pharmaceutica Nv Benzo[1,2,5]thiadiazole compounds as CCK2 modulators
CN101061116A (zh) * 2004-09-24 2007-10-24 詹森药业有限公司 磺酰胺化合物
US20060177438A1 (en) * 2005-02-08 2006-08-10 New England Medical Center Methods of altering absorption of hydrophobic compounds
CN102757427A (zh) * 2012-07-09 2012-10-31 陕西科技大学 2-氨基-5-异二氢吲哚-1,3-二酮甲基1,3,4-噻二唑及其制备方法
CN103601699A (zh) * 2013-11-04 2014-02-26 南京大学 一类1,3,4-噻二唑-2-酰胺衍生物及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874864A (en) * 1988-05-24 1989-10-17 Pfizer Inc. Benzamide protease inhibitors
IE68593B1 (en) * 1989-12-06 1996-06-26 Sanofi Sa Heterocyclic substituted acylaminothiazoles their preparation and pharmaceutical compositions containing them
GB9008123D0 (en) * 1990-04-10 1990-06-06 Lilly Industries Ltd Pharmaceutical compounds
FR2677356B1 (fr) * 1991-06-05 1995-03-17 Sanofi Sa Derives heterocycliques d'acylamino-2 thiazoles-5 substitues, leur preparation et compositions pharmaceutiques en contenant.

Also Published As

Publication number Publication date
AU5945094A (en) 1994-10-27
HU9401092D0 (en) 1994-07-28
AU678208B2 (en) 1997-05-22
HU217549B (hu) 2000-02-28
IL109275A (en) 1998-02-08
RU2129550C1 (ru) 1999-04-27
FR2703995B1 (fr) 1995-07-21
NO941374D0 (no) 1994-04-15
NZ260313A (en) 1994-12-22
ZA942577B (en) 1995-10-16
JP3029372B2 (ja) 2000-04-04
FR2703995A1 (fr) 1994-10-21
FI941776A (fi) 1994-10-17
EP0620221A1 (fr) 1994-10-19
FI941776A0 (fi) 1994-04-15
CN1050128C (zh) 2000-03-08
US5534530A (en) 1996-07-09
JPH06340663A (ja) 1994-12-13
NO941374L (no) 1994-10-17
CN1100724A (zh) 1995-03-29
CA2121425A1 (en) 1994-10-17
HUT70542A (en) 1995-10-30
IL109275A0 (en) 1994-07-31
TW295584B (xx) 1997-01-11

Similar Documents

Publication Publication Date Title
US6380230B1 (en) Carboxamidothiazole derivatives, preparation, pharmaceutical compositions containing them
AU728329B2 (en) New substituted biphenyl or phenylpyridine compounds, a process for their preparation and pharmaceutical compositions containing them
US5618833A (en) 1-benzyl-1,3-dihydroindol-2-one derivatives, their preparation and the pharmaceutical compositions in which they are present
NO301163B1 (no) 5-Acylamino-1,2,4-tiadiazoler, og farmasöytiske blandinger inneholdende dem
EP1715862A1 (en) Kinase inhibitors
RU2125569C1 (ru) Производные полизамещенных 2-амидо-4-фенилтиазолов, способ их получения, промежуточные соединения синтеза и фармацевтическая композиция на их основе
WO1992013856A1 (en) 5-heteroyl indole derivatives
AU635593B2 (en) Azaoxindole derivatives
JPH11506472A (ja) 5―ht1aおよび/または5―ht1d受容体の選択的(アンタ)アゴニストとしてのベンジル(イデン)―ラクタム誘導体、その調製法及びその使用法
AU4876900A (en) New beta-carboline compounds a process for their preparation and pharmaceutical compositions containing them
JPH07300467A (ja) 多置換3−アシルアミノ−5−フェニル−1,4−ベンゾジアゼピン−2−オン誘導体、その製造方法およびそれを含有する医薬組成物
IL203956A (en) Indole-2-on-2 derivatives are positioned in position 3, their preparation and use for drug preparation
AU2003267041A1 (en) N-substituted-1h-indol-5-propionic acid compounds as ppar agonists useful for the treatment of diabetes
KR100248643B1 (ko) 아릴 및 헤테로아릴 알콕시나프탈렌 유도체
ES2257168B1 (es) Ligandos del receptor 5-ht7.
JP2001525398A (ja) 選択的β3アドレナリン作動性アゴニスト
GB2126230A (en) Substituted 1-pyridyloxy-3- indolylakylamino-2-propanols, preparation, and use thereof
KR880002272B1 (ko) 1-치환된 옥신돌-3-카복사마이드의 제조방법
MXPA00002767A (en) Carboxamidothiazole derivatives, preparation, pharmaceutical compositions containing them
CZ2000977A3 (cs) Karboxamidothiazolové deriváty, způsob jejich přípravy a farmaceutické prostředky s jejich obsahem

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN OCTOBER 2001