NO2968302T3 - - Google Patents
Info
- Publication number
- NO2968302T3 NO2968302T3 NO14725812A NO14725812A NO2968302T3 NO 2968302 T3 NO2968302 T3 NO 2968302T3 NO 14725812 A NO14725812 A NO 14725812A NO 14725812 A NO14725812 A NO 14725812A NO 2968302 T3 NO2968302 T3 NO 2968302T3
- Authority
- NO
- Norway
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261718966P | 2012-10-26 | 2012-10-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO2968302T3 true NO2968302T3 (no) | 2018-02-03 |
Family
ID=50545344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO14725812A NO2968302T3 (no) | 2012-10-26 | 2014-03-14 |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US9777038B2 (no) |
| EP (1) | EP2912013B1 (no) |
| JP (1) | JP6272888B2 (no) |
| KR (1) | KR102068381B1 (no) |
| CN (2) | CN108250264A (no) |
| AU (1) | AU2013334122B2 (no) |
| BR (1) | BR112015009395A2 (no) |
| CA (1) | CA2889592A1 (no) |
| CY (1) | CY1119731T1 (no) |
| DK (1) | DK2912013T3 (no) |
| ES (1) | ES2655034T3 (no) |
| HK (2) | HK1214239A1 (no) |
| HU (1) | HUE036887T2 (no) |
| IL (1) | IL238454B (no) |
| MX (1) | MX361653B (no) |
| NO (1) | NO2968302T3 (no) |
| NZ (2) | NZ745013A (no) |
| PL (1) | PL2912013T3 (no) |
| PT (1) | PT2912013T (no) |
| SG (1) | SG11201503247UA (no) |
| WO (1) | WO2014066819A1 (no) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014066819A1 (en) | 2012-10-26 | 2014-05-01 | Intercept Pharmaceuticals, Inc. | Process for preparing bile acid derivatives |
| SG11201609403UA (en) * | 2014-05-29 | 2016-12-29 | Bar Pharmaceuticals S R L | Cholane derivatives for use in the treatment and/or prevention of fxr and tgr5/gpbar1 mediated diseases |
| EA033445B1 (ru) | 2014-11-19 | 2019-10-31 | Nzp Uk Ltd | 5-бета-6-алкил-7-гидрокси-3-оновые стероиды в качестве промежуточных соединений для получения стероидных модуляторов fxr |
| CA2968310A1 (en) | 2014-11-19 | 2016-05-26 | NZP UK Limited | 6.alpha.-alkyl-6,7-dione steroids as intermediates for the production of steroidal fxr modulators |
| EP3221333B1 (en) | 2014-11-19 | 2019-07-24 | NZP UK Limited | 6.alpha.-alkyl-3,7-dione steroids as intermediates for the production of steroidal fxr modulators |
| MX2017006563A (es) | 2014-11-19 | 2018-01-26 | Nzp Uk Ltd | Esteroides de 6-alquil-7-hidroxi-4-en-3-ona como intermedios para la produccion de moduladores esteroides del receptor x farnesoide (fxr). |
| CN104672290B (zh) * | 2015-01-05 | 2017-06-06 | 北京普禄德医药科技有限公司 | 一种用于预防或治疗fxr‑介导的疾病的药物及其制备方法和用途 |
| KR20170115071A (ko) | 2015-02-06 | 2017-10-16 | 인터셉트 파마슈티컬즈, 인크. | 병용 요법을 위한 약제학적 조성물 |
| MX2018003649A (es) | 2015-09-24 | 2018-05-11 | Intercept Pharmaceuticals Inc | Metodos e intermedios para la preparacion de derivados de acido biliar. |
| MX2018005520A (es) * | 2015-11-06 | 2018-08-01 | Intercept Pharmaceuticals Inc | Metodos para preparacion de acido obeticolico y derivados de los mismos. |
| WO2017142895A1 (en) * | 2016-02-15 | 2017-08-24 | Regents Of The University Of Minnesota | Compositions and methods for treating clostridium associated diseases |
| CA3020698A1 (en) | 2016-04-13 | 2017-10-19 | Intercept Pharmaceuticals, Inc. | Methods of treating or preventing hepatocellular carcinoma |
| TW201738254A (zh) | 2016-04-19 | 2017-11-01 | 英特賽普醫藥品公司 | 奧貝膽酸及其衍生物之製備方法 |
| GB201608777D0 (en) | 2016-05-18 | 2016-06-29 | Dextra Lab Ltd | Compounds |
| GB201608776D0 (en) | 2016-05-18 | 2016-06-29 | Dextra Lab Ltd | Methods and compounds |
| JP2019529481A (ja) * | 2016-09-30 | 2019-10-17 | インターセプト ファーマシューティカルズ， インコーポレイテッド | 胆汁酸誘導体の結晶形態 |
| EP3658150A4 (en) | 2017-07-24 | 2021-03-31 | Intercept Pharmaceuticals, Inc. | Isotopically labeled gallic acid derivatives |
| CN110869381B (zh) * | 2017-07-26 | 2021-11-19 | 正大天晴药业集团股份有限公司 | 甾体类衍生物fxr激动剂的制备方法 |
| GB201812382D0 (en) | 2018-07-30 | 2018-09-12 | Nzp Uk Ltd | Compounds |
| CN114144185A (zh) | 2019-05-30 | 2022-03-04 | 英特塞普特医药品公司 | 用于治疗胆汁淤积性肝病的包含fxr激动剂和贝特类的药物组合物 |
| BR112022006546A2 (pt) | 2019-10-07 | 2022-08-30 | Kallyope Inc | Agonistas de gpr119 |
| AU2021275038A1 (en) | 2020-05-19 | 2022-12-22 | Kallyope, Inc. | AMPK activators |
| CN116390925A (zh) | 2020-06-26 | 2023-07-04 | 卡尔优普公司 | Ampk活化剂 |
| JP2023542365A (ja) | 2020-09-18 | 2023-10-06 | ソウル大学校産学協力団 | タウロデオキシコール酸ナトリウムの大量生産方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5216015A (en) * | 1991-02-05 | 1993-06-01 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Compounds having hypocholesterolemic properties |
| AU2002308295B2 (en) | 2001-03-12 | 2007-08-23 | Intercept Pharmaceuticals, Inc. | Steroids as agonists for FXR |
| EP1568706A1 (en) * | 2004-02-26 | 2005-08-31 | Intercept Pharmaceuticals, Inc. | Novel steroid agonist for FXR |
| CA2656320C (en) * | 2006-06-27 | 2015-04-28 | Intercept Pharmaceuticals, Inc. | Bile acid derivatives as fxr ligands for the prevention or treatment of fxr-mediated diseases or conditions |
| WO2010036427A1 (en) * | 2008-06-17 | 2010-04-01 | Brigham Young University | Cationic steroid antimicrobial diagnostic, detection, screening and imaging methods |
| BRPI0916735B8 (pt) * | 2008-07-30 | 2021-05-25 | Intercept Pharmaceuticals Inc | compostos moduladores de tgr5, composições farmacêuticas compreendendo os mesmos e seus usos |
| WO2010059859A1 (en) * | 2008-11-19 | 2010-05-27 | Intercept Pharmaceuticals, Inc. | Tgr5 modulators and methods of use thereof |
| WO2014066819A1 (en) | 2012-10-26 | 2014-05-01 | Intercept Pharmaceuticals, Inc. | Process for preparing bile acid derivatives |
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2013
- 2013-10-25 WO PCT/US2013/066917 patent/WO2014066819A1/en active Application Filing
- 2013-10-25 BR BR112015009395A patent/BR112015009395A2/pt not_active Application Discontinuation
- 2013-10-25 SG SG11201503247UA patent/SG11201503247UA/en unknown
- 2013-10-25 CA CA2889592A patent/CA2889592A1/en not_active Abandoned
- 2013-10-25 HU HUE13849263A patent/HUE036887T2/hu unknown
- 2013-10-25 PT PT138492632T patent/PT2912013T/pt unknown
- 2013-10-25 JP JP2015539862A patent/JP6272888B2/ja not_active Expired - Fee Related
- 2013-10-25 NZ NZ745013A patent/NZ745013A/en not_active IP Right Cessation
- 2013-10-25 EP EP13849263.2A patent/EP2912013B1/en active Active
- 2013-10-25 NZ NZ707389A patent/NZ707389A/en not_active IP Right Cessation
- 2013-10-25 PL PL13849263T patent/PL2912013T3/pl unknown
- 2013-10-25 CN CN201810282054.XA patent/CN108250264A/zh active Pending
- 2013-10-25 AU AU2013334122A patent/AU2013334122B2/en not_active Ceased
- 2013-10-25 CN CN201380068062.XA patent/CN105102425B/zh not_active Expired - Fee Related
- 2013-10-25 US US14/438,323 patent/US9777038B2/en active Active
- 2013-10-25 ES ES13849263.2T patent/ES2655034T3/es active Active
- 2013-10-25 KR KR1020157012805A patent/KR102068381B1/ko active IP Right Grant
- 2013-10-25 DK DK13849263.2T patent/DK2912013T3/en active
- 2013-10-25 MX MX2015005286A patent/MX361653B/es active IP Right Grant
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2014
- 2014-03-14 NO NO14725812A patent/NO2968302T3/no unknown
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2015
- 2015-04-26 IL IL238454A patent/IL238454B/en active IP Right Grant
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2016
- 2016-02-24 HK HK16102102.3A patent/HK1214239A1/zh not_active IP Right Cessation
- 2016-02-24 HK HK18112593.6A patent/HK1253301A1/zh unknown
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2017
- 2017-08-21 US US15/681,609 patent/US10202414B2/en not_active Expired - Fee Related
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2018
- 2018-01-03 CY CY20181100003T patent/CY1119731T1/el unknown