NO2968302T3 - - Google Patents
Info
- Publication number
- NO2968302T3 NO2968302T3 NO14725812A NO14725812A NO2968302T3 NO 2968302 T3 NO2968302 T3 NO 2968302T3 NO 14725812 A NO14725812 A NO 14725812A NO 14725812 A NO14725812 A NO 14725812A NO 2968302 T3 NO2968302 T3 NO 2968302T3
- Authority
- NO
- Norway
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261718966P | 2012-10-26 | 2012-10-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO2968302T3 true NO2968302T3 (enExample) | 2018-02-03 |
Family
ID=50545344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO14725812A NO2968302T3 (enExample) | 2012-10-26 | 2014-03-14 |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US9777038B2 (enExample) |
| EP (1) | EP2912013B1 (enExample) |
| JP (1) | JP6272888B2 (enExample) |
| KR (1) | KR102068381B1 (enExample) |
| CN (2) | CN105102425B (enExample) |
| AU (1) | AU2013334122B2 (enExample) |
| BR (1) | BR112015009395A2 (enExample) |
| CA (1) | CA2889592A1 (enExample) |
| CY (1) | CY1119731T1 (enExample) |
| DK (1) | DK2912013T3 (enExample) |
| ES (1) | ES2655034T3 (enExample) |
| HK (1) | HK1253301A1 (enExample) |
| HU (1) | HUE036887T2 (enExample) |
| IL (1) | IL238454B (enExample) |
| MX (1) | MX361653B (enExample) |
| NO (1) | NO2968302T3 (enExample) |
| NZ (2) | NZ707389A (enExample) |
| PL (1) | PL2912013T3 (enExample) |
| PT (1) | PT2912013T (enExample) |
| SG (1) | SG11201503247UA (enExample) |
| SM (1) | SMT201700602T1 (enExample) |
| WO (1) | WO2014066819A1 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE036887T2 (hu) | 2012-10-26 | 2018-08-28 | Intercept Pharmaceuticals Inc | Eljárás epesav-származékok elõállítására |
| EP3626725B1 (en) * | 2014-05-29 | 2022-11-30 | Bar Pharmaceuticals S.r.l. | Cholane derivatives for use in the treatment and/or prevention of fxr and tgr5/gpbar1 mediated diseases |
| EA033445B1 (ru) | 2014-11-19 | 2019-10-31 | Nzp Uk Ltd | 5-бета-6-алкил-7-гидрокси-3-оновые стероиды в качестве промежуточных соединений для получения стероидных модуляторов fxr |
| EP3221333B1 (en) | 2014-11-19 | 2019-07-24 | NZP UK Limited | 6.alpha.-alkyl-3,7-dione steroids as intermediates for the production of steroidal fxr modulators |
| EP3221331B1 (en) | 2014-11-19 | 2019-09-18 | Nzp Uk Limited | 6-alkyl-7-hydroxy-4-en-3-one steroids as intermediates for the production of steroidal fxr modulators |
| JP6698085B2 (ja) | 2014-11-19 | 2020-05-27 | エヌゼットピー ユーケー リミテッド | ステロイドＦＸＲモジュレーター製造のための中間体としての６α−アルキル−６，７−ジオン−ステロイド |
| CN104672290B (zh) * | 2015-01-05 | 2017-06-06 | 北京普禄德医药科技有限公司 | 一种用于预防或治疗fxr‑介导的疾病的药物及其制备方法和用途 |
| TN2017000344A1 (en) | 2015-02-06 | 2019-01-16 | Intercept Pharmaceuticals Inc | Pharmaceutical compositions for combination therapy |
| CN108350020A (zh) * | 2015-09-24 | 2018-07-31 | 英特塞普特医药品公司 | 用于制备胆汁酸衍生物的方法和中间体 |
| KR20180067699A (ko) | 2015-11-06 | 2018-06-20 | 인터셉트 파마슈티컬즈, 인크. | 오베티콜산 및 이의 유도체의 제조 방법 |
| WO2017142895A1 (en) * | 2016-02-15 | 2017-08-24 | Regents Of The University Of Minnesota | Compositions and methods for treating clostridium associated diseases |
| WO2017180577A1 (en) | 2016-04-13 | 2017-10-19 | Intercept Pharmaceuticals, Inc. | Methods of treating cancer |
| TW201738254A (zh) * | 2016-04-19 | 2017-11-01 | 英特賽普醫藥品公司 | 奧貝膽酸及其衍生物之製備方法 |
| GB201608776D0 (en) | 2016-05-18 | 2016-06-29 | Dextra Lab Ltd | Methods and compounds |
| GB201608777D0 (en) | 2016-05-18 | 2016-06-29 | Dextra Lab Ltd | Compounds |
| CA3038534A1 (en) * | 2016-09-30 | 2018-04-05 | Intercept Pharmaceuticals, Inc. | Crystalline forms of a bile acid derivative |
| MX2020000873A (es) * | 2017-07-24 | 2020-07-22 | Intercept Pharmaceuticals Inc | Derivados de ácidos biliares marcados isotópicamente. |
| WO2019020067A1 (zh) * | 2017-07-26 | 2019-01-31 | 正大天晴药业集团股份有限公司 | 甾体类衍生物fxr激动剂的制备方法 |
| GB201812382D0 (en) | 2018-07-30 | 2018-09-12 | Nzp Uk Ltd | Compounds |
| EA202193334A1 (ru) | 2019-05-30 | 2022-03-14 | Интерсепт Фармасьютикалз, Инк. | Фармацевтические композиции, содержащие агонист fxr и фибрат, для применения при лечении холестатического заболевания печени |
| BR112022006546A2 (pt) | 2019-10-07 | 2022-08-30 | Kallyope Inc | Agonistas de gpr119 |
| CA3173731A1 (en) | 2020-02-28 | 2021-09-02 | Kallyope, Inc. | Gpr40 agonists |
| CN116323608A (zh) | 2020-05-19 | 2023-06-23 | 卡尔优普公司 | Ampk活化剂 |
| EP4172162A4 (en) | 2020-06-26 | 2024-08-07 | Kallyope, Inc. | AMPK ACTIVATORS |
| WO2022059948A1 (ko) | 2020-09-18 | 2022-03-24 | 서울대학교 산학협력단 | 소디움 타우로디옥시콜레이트의 대량 생산 방법 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5216015A (en) * | 1991-02-05 | 1993-06-01 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Compounds having hypocholesterolemic properties |
| ATE303399T1 (de) * | 2001-03-12 | 2005-09-15 | Intercept Pharmaceuticals Inc | Steroide als agonisten für fxr |
| EP1568706A1 (en) | 2004-02-26 | 2005-08-31 | Intercept Pharmaceuticals, Inc. | Novel steroid agonist for FXR |
| CN101522703B (zh) * | 2006-06-27 | 2013-04-17 | 英特塞普特医药品公司 | 胆酸派生物及其在制备预防或治疗fxr介导的疾病或状况的药物中的应用 |
| US9943614B2 (en) * | 2008-06-17 | 2018-04-17 | Brigham Young University | Cationic steroid antimicrobial diagnostic, detection, screening and imaging methods |
| EA020310B1 (ru) * | 2008-07-30 | 2014-10-30 | Интерсепт Фармасьютикалз, Инк. | Модуляторы рецептора tgr5 и их применение |
| CA2744135C (en) * | 2008-11-19 | 2017-07-04 | Intercept Pharmaceuticals, Inc. | Tgr5 modulators and methods of use thereof |
| HUE036887T2 (hu) | 2012-10-26 | 2018-08-28 | Intercept Pharmaceuticals Inc | Eljárás epesav-származékok elõállítására |
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2013
- 2013-10-25 HU HUE13849263A patent/HUE036887T2/hu unknown
- 2013-10-25 NZ NZ707389A patent/NZ707389A/en not_active IP Right Cessation
- 2013-10-25 NZ NZ745013A patent/NZ745013A/en not_active IP Right Cessation
- 2013-10-25 KR KR1020157012805A patent/KR102068381B1/ko not_active Expired - Fee Related
- 2013-10-25 JP JP2015539862A patent/JP6272888B2/ja not_active Expired - Fee Related
- 2013-10-25 ES ES13849263.2T patent/ES2655034T3/es active Active
- 2013-10-25 WO PCT/US2013/066917 patent/WO2014066819A1/en not_active Ceased
- 2013-10-25 PT PT138492632T patent/PT2912013T/pt unknown
- 2013-10-25 US US14/438,323 patent/US9777038B2/en active Active
- 2013-10-25 SM SM20170602T patent/SMT201700602T1/it unknown
- 2013-10-25 SG SG11201503247UA patent/SG11201503247UA/en unknown
- 2013-10-25 CN CN201380068062.XA patent/CN105102425B/zh not_active Expired - Fee Related
- 2013-10-25 EP EP13849263.2A patent/EP2912013B1/en not_active Not-in-force
- 2013-10-25 DK DK13849263.2T patent/DK2912013T3/en active
- 2013-10-25 AU AU2013334122A patent/AU2013334122B2/en not_active Ceased
- 2013-10-25 MX MX2015005286A patent/MX361653B/es active IP Right Grant
- 2013-10-25 CA CA2889592A patent/CA2889592A1/en not_active Abandoned
- 2013-10-25 PL PL13849263T patent/PL2912013T3/pl unknown
- 2013-10-25 BR BR112015009395A patent/BR112015009395A2/pt not_active Application Discontinuation
- 2013-10-25 CN CN201810282054.XA patent/CN108250264A/zh active Pending
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2014
- 2014-03-14 NO NO14725812A patent/NO2968302T3/no unknown
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2015
- 2015-04-26 IL IL238454A patent/IL238454B/en active IP Right Grant
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2016
- 2016-02-24 HK HK18112593.6A patent/HK1253301A1/zh unknown
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2017
- 2017-08-21 US US15/681,609 patent/US10202414B2/en not_active Expired - Fee Related
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2018
- 2018-01-03 CY CY20181100003T patent/CY1119731T1/el unknown