NO2480669T3 - - Google Patents

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Publication number
NO2480669T3
NO2480669T3 NO10819521A NO10819521A NO2480669T3 NO 2480669 T3 NO2480669 T3 NO 2480669T3 NO 10819521 A NO10819521 A NO 10819521A NO 10819521 A NO10819521 A NO 10819521A NO 2480669 T3 NO2480669 T3 NO 2480669T3
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NO
Norway
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NO10819521A
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Norwegian (no)
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/315—Phosphorothioates
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    • C12N2310/318—Chemical structure of the backbone where the PO2 is completely replaced, e.g. MMI or formacetal
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    • C12N2310/32—Chemical structure of the sugar
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    • C12N2310/323—Chemical structure of the sugar modified ring structure
    • C12N2310/3231—Chemical structure of the sugar modified ring structure having an additional ring, e.g. LNA, ENA

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
NO10819521A 2009-09-25 2010-09-24 NO2480669T3 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24608009P 2009-09-25 2009-09-25
US30765410P 2010-02-24 2010-02-24
PCT/US2010/050173 WO2011038210A2 (fr) 2009-09-25 2010-09-24 Traitement de maladies associées à la filaggrine (flg) par modulation de l'expression et de l'activité de flg

Publications (1)

Publication Number Publication Date
NO2480669T3 true NO2480669T3 (fr) 2018-04-07

Family

ID=43796503

Family Applications (1)

Application Number Title Priority Date Filing Date
NO10819521A NO2480669T3 (fr) 2009-09-25 2010-09-24

Country Status (10)

Country Link
US (3) US20120295952A1 (fr)
EP (1) EP2480669B1 (fr)
JP (3) JP6175236B2 (fr)
KR (1) KR101802540B1 (fr)
CN (1) CN102791861B (fr)
CA (1) CA2775111C (fr)
DK (1) DK2480669T3 (fr)
ES (1) ES2664591T3 (fr)
NO (1) NO2480669T3 (fr)
WO (1) WO2011038210A2 (fr)

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* Cited by examiner, † Cited by third party
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KR101802540B1 (ko) 2009-09-25 2017-11-28 큐알엔에이, 인크. Ｆｌｇ의 발현 및 활성을 조절함으로써 필라그린(ｆｌｇ)에 관련된 질환의 치료
CA2781537C (fr) 2009-11-23 2022-06-28 Research Development Foundation Polypeptides recombinants derives de filaggrine destines a l'importation de cellules
US9920317B2 (en) 2010-11-12 2018-03-20 The General Hospital Corporation Polycomb-associated non-coding RNAs
WO2012065143A1 (fr) 2010-11-12 2012-05-18 The General Hospital Corporation Arn non codants associés à polycomb
US20130123647A1 (en) 2011-05-03 2013-05-16 The Research Foundation Of State University Of New York Methods Useful in Optimizing the Treatment of Neuropathies and Targeting Tissues with Cosmetic Botulinum Injections
EP2753320A1 (fr) * 2011-09-08 2014-07-16 Merz Pharma GmbH & Co. KGaA Utilisation de dérivés d'adamantane pour le traitement d'une kératose actinique
CN102604994B (zh) * 2012-03-06 2014-03-26 党宁宁 一种针对flg基因rna干扰的重组慢病毒载体及其制备
DK2850186T3 (en) 2012-05-16 2019-04-08 Translate Bio Ma Inc COMPOSITIONS AND PROCEDURES FOR MODULATING SMN GENFAMILY EXPRESSION
AP2014008100A0 (en) 2012-05-16 2014-12-31 Gen Hospital Corp Compositions and methods for modulating hemoglobingene family expression
EA201492122A1 (ru) 2012-05-16 2015-10-30 Рана Терапьютикс, Инк. Композиции и способы для модулирования экспрессии utrn
US10837014B2 (en) 2012-05-16 2020-11-17 Translate Bio Ma, Inc. Compositions and methods for modulating SMN gene family expression
WO2013173608A1 (fr) 2012-05-16 2013-11-21 Rana Therapeutics, Inc. Compositions et méthodes pour moduler l'expression de mecp2
CN104583401A (zh) 2012-05-16 2015-04-29 Rana医疗有限公司 用于调节atp2a2表达的组合物和方法
US8652527B1 (en) 2013-03-13 2014-02-18 Upsher-Smith Laboratories, Inc Extended-release topiramate capsules
US9101545B2 (en) 2013-03-15 2015-08-11 Upsher-Smith Laboratories, Inc. Extended-release topiramate capsules
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WO2011038210A2 (fr) 2011-03-31
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JP2017184741A (ja) 2017-10-12
US11390868B2 (en) 2022-07-19
US20120295952A1 (en) 2012-11-22
EP2480669B1 (fr) 2017-11-08
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CN102791861A (zh) 2012-11-21
US20150152417A1 (en) 2015-06-04
KR101802540B1 (ko) 2017-11-28
JP2013505724A (ja) 2013-02-21
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DK2480669T3 (en) 2018-02-12
WO2011038210A3 (fr) 2011-10-20
CA2775111A1 (fr) 2011-03-31
EP2480669A4 (fr) 2013-07-31
US20190024084A1 (en) 2019-01-24
ES2664591T3 (es) 2018-04-20
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CA2775111C (fr) 2019-12-31
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