NO20092722L - Fast dispersjon av en neurokininantagonist - Google Patents
Fast dispersjon av en neurokininantagonistInfo
- Publication number
- NO20092722L NO20092722L NO20092722A NO20092722A NO20092722L NO 20092722 L NO20092722 L NO 20092722L NO 20092722 A NO20092722 A NO 20092722A NO 20092722 A NO20092722 A NO 20092722A NO 20092722 L NO20092722 L NO 20092722L
- Authority
- NO
- Norway
- Prior art keywords
- solid dispersion
- neurokinin antagonist
- disorders
- functional
- bistrifluoromethylbenzoyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Dispersion Chemistry (AREA)
- Nutrition Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Det beskrives en fast dispersjon omfattende (4R)-4-[N'-metyI-N'-(3,5-bistrifluormetyIbenzoyl)-aminol-4-(3,4-diklorbenzyl)-but-2-enoinsyre N-[(R)-epsilon-kaprolaktam-3yl]-amid eller et farmasøytisk akseptabelt salt eller solvat derav og en bærer. Farmasøytiske preparater omfattende en slik fast dispersjon er nyttige for behandling av pasienter som har funksjonelle motilitetsforstyrrelser av visceral, særlig irritabel tarmsyndrom eller funksjonelle dyspepsi, eller urinblæreforstyrrelser og særlig urininkontinens.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06126964A EP1938804A1 (en) | 2006-12-22 | 2006-12-22 | Pharmaceutical formulation comprising neurokinin antagonist |
PCT/EP2007/011293 WO2008077591A2 (en) | 2006-12-22 | 2007-12-20 | Pharmaceutical formulation comprising neurokinin antagonist |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20092722L true NO20092722L (no) | 2009-07-21 |
Family
ID=37762542
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20092722A NO20092722L (no) | 2006-12-22 | 2009-07-17 | Fast dispersjon av en neurokininantagonist |
Country Status (25)
Country | Link |
---|---|
US (1) | US20100015225A1 (no) |
EP (2) | EP1938804A1 (no) |
JP (1) | JP2010513356A (no) |
KR (1) | KR20090092288A (no) |
CN (1) | CN101541309A (no) |
AR (1) | AR064622A1 (no) |
AU (1) | AU2007338359B2 (no) |
BR (1) | BRPI0720937A2 (no) |
CA (1) | CA2672402A1 (no) |
CL (1) | CL2007003767A1 (no) |
CO (1) | CO6180497A2 (no) |
EA (1) | EA200900827A1 (no) |
EC (1) | ECSP099450A (no) |
GT (1) | GT200900173A (no) |
IL (1) | IL198780A0 (no) |
MA (1) | MA31004B1 (no) |
MX (1) | MX2009006747A (no) |
MY (1) | MY145919A (no) |
NO (1) | NO20092722L (no) |
NZ (1) | NZ576987A (no) |
PE (1) | PE20081848A1 (no) |
TN (1) | TN2009000253A1 (no) |
TW (1) | TW200848056A (no) |
WO (1) | WO2008077591A2 (no) |
ZA (1) | ZA200903271B (no) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI398433B (zh) * | 2006-02-10 | 2013-06-11 | Dow Agrosciences Llc | 殺蟲性之n-取代(6-鹵烷基吡啶-3-基)烷基磺醯亞胺 |
WO2010092925A1 (ja) * | 2009-02-12 | 2010-08-19 | あすか製薬株式会社 | 固体分散体とその医薬組成物、並びにそれらの製造方法 |
JP5425229B2 (ja) * | 2009-02-24 | 2014-02-26 | ノバルティス アーゲー | Nk受容体アンタゴニストの使用 |
US8263119B2 (en) * | 2010-12-01 | 2012-09-11 | Shire Llc | Capsule formulations containing lanthanum compounds |
AU2013207252B2 (en) | 2012-01-06 | 2016-06-09 | H.Lundbeck A/S | Carbamate compounds and pharmaceutical compositions thereof |
CN107529758B (zh) * | 2015-03-10 | 2021-01-26 | 盐野义制药公司 | 固体分散体 |
CN107849021A (zh) | 2015-05-11 | 2018-03-27 | 阿比德治疗公司 | 治疗炎症或神经性疼痛的方法 |
CN110291083B (zh) | 2016-11-16 | 2022-06-17 | H.隆德贝克有限公司 | Magl抑制剂的结晶形式 |
JP2020500176A (ja) | 2016-11-16 | 2020-01-09 | ルンドベック ラ ホーヤ リサーチ センター,インク. | 医薬製剤 |
IL297470A (en) | 2020-04-21 | 2022-12-01 | H Lundbeck As | Synthesis of a monoacylglycerol lipase inhibitor |
CN111904960A (zh) * | 2020-05-19 | 2020-11-10 | 合肥合源药业有限公司 | 一种固体分散体及药用组合物 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3622677A (en) * | 1969-07-07 | 1971-11-23 | Staley Mfg Co A E | Compressed tablets containing compacted starch as binder-disintegrant ingredient |
JPH054919A (ja) * | 1990-07-25 | 1993-01-14 | Sankyo Co Ltd | チアゾリジン誘導体の固体分散体 |
MY132550A (en) * | 1996-08-22 | 2007-10-31 | Novartis Ag | Acylaminoalkenylene-amide derivatives as nk1 and nk2 antogonists |
US6342245B1 (en) * | 1997-11-03 | 2002-01-29 | Janssen Pharmaceutica N.V. | Compositions of lipid lowering agents |
TWI235068B (en) * | 1998-03-26 | 2005-07-01 | Fujisawa Pharmaceutical Co | Sustained-release pharmaceutical composition |
AR028253A1 (es) * | 2000-03-16 | 2003-04-30 | Pfizer Prod Inc | Inhibidores de la glucogeno fosforilasa |
JP2004131393A (ja) * | 2002-10-08 | 2004-04-30 | Kowa Co | 易溶出性製剤 |
GB2394417A (en) * | 2002-10-24 | 2004-04-28 | Novartis Ag | Solid dispersion comprising a piperidine substance P antagonist and a carrier |
EP2158910A1 (en) * | 2003-10-27 | 2010-03-03 | Novartis Ag | Use of neurokinin antagonists in the treatment of urinary incontinence |
GB0402679D0 (en) * | 2004-02-06 | 2004-03-10 | Novartis Ag | Organic compounds |
KR100627687B1 (ko) * | 2005-04-20 | 2006-09-25 | 주식회사 씨티씨바이오 | 시부트라민 유리염기 함유 조성물 및 이의 제조방법 |
EP1871346A4 (en) * | 2005-04-20 | 2012-07-18 | Ctc Bio Inc | PHARMACEUTICAL COMPOSITION WITH FREE BASE FROM SIBUTRAMIN AND MANUFACTURING METHOD THEREFOR |
-
2006
- 2006-12-22 EP EP06126964A patent/EP1938804A1/en not_active Ceased
-
2007
- 2007-12-20 CN CNA2007800435054A patent/CN101541309A/zh active Pending
- 2007-12-20 US US12/520,312 patent/US20100015225A1/en not_active Abandoned
- 2007-12-20 KR KR1020097012819A patent/KR20090092288A/ko not_active Application Discontinuation
- 2007-12-20 AU AU2007338359A patent/AU2007338359B2/en not_active Ceased
- 2007-12-20 BR BRPI0720937-1A patent/BRPI0720937A2/pt not_active IP Right Cessation
- 2007-12-20 NZ NZ576987A patent/NZ576987A/en not_active IP Right Cessation
- 2007-12-20 CA CA002672402A patent/CA2672402A1/en not_active Abandoned
- 2007-12-20 JP JP2009541897A patent/JP2010513356A/ja active Pending
- 2007-12-20 AR ARP070105788A patent/AR064622A1/es not_active Application Discontinuation
- 2007-12-20 MX MX2009006747A patent/MX2009006747A/es not_active Application Discontinuation
- 2007-12-20 EA EA200900827A patent/EA200900827A1/ru unknown
- 2007-12-20 WO PCT/EP2007/011293 patent/WO2008077591A2/en active Application Filing
- 2007-12-20 MY MYPI20092111A patent/MY145919A/en unknown
- 2007-12-20 EP EP07857016A patent/EP2117511A2/en not_active Withdrawn
- 2007-12-21 TW TW096149580A patent/TW200848056A/zh unknown
- 2007-12-21 CL CL200703767A patent/CL2007003767A1/es unknown
-
2008
- 2008-01-02 PE PE2008000080A patent/PE20081848A1/es not_active Application Discontinuation
-
2009
- 2009-05-12 ZA ZA200903271A patent/ZA200903271B/xx unknown
- 2009-05-14 IL IL198780A patent/IL198780A0/en unknown
- 2009-06-17 MA MA32008A patent/MA31004B1/fr unknown
- 2009-06-17 CO CO09062883A patent/CO6180497A2/es not_active Application Discontinuation
- 2009-06-19 TN TNP2009000253A patent/TN2009000253A1/fr unknown
- 2009-06-19 GT GT200900173A patent/GT200900173A/es unknown
- 2009-06-22 EC EC2009009450A patent/ECSP099450A/es unknown
- 2009-07-17 NO NO20092722A patent/NO20092722L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN101541309A (zh) | 2009-09-23 |
CL2007003767A1 (es) | 2008-07-18 |
JP2010513356A (ja) | 2010-04-30 |
WO2008077591A3 (en) | 2009-04-09 |
ZA200903271B (en) | 2010-04-28 |
CA2672402A1 (en) | 2008-07-03 |
AR064622A1 (es) | 2009-04-15 |
US20100015225A1 (en) | 2010-01-21 |
TN2009000253A1 (en) | 2010-10-18 |
AU2007338359A1 (en) | 2008-07-03 |
NZ576987A (en) | 2011-10-28 |
TW200848056A (en) | 2008-12-16 |
AU2007338359B2 (en) | 2011-04-28 |
MY145919A (en) | 2012-05-15 |
CO6180497A2 (es) | 2010-07-19 |
ECSP099450A (es) | 2009-07-31 |
MX2009006747A (es) | 2009-06-30 |
GT200900173A (es) | 2010-06-24 |
PE20081848A1 (es) | 2009-01-19 |
BRPI0720937A2 (pt) | 2014-03-11 |
MA31004B1 (fr) | 2009-12-01 |
WO2008077591A2 (en) | 2008-07-03 |
EP1938804A1 (en) | 2008-07-02 |
IL198780A0 (en) | 2010-02-17 |
KR20090092288A (ko) | 2009-08-31 |
EP2117511A2 (en) | 2009-11-18 |
EA200900827A1 (ru) | 2009-12-30 |
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