NO20090268L - Benzofuro- and benzothienopyrimidine modulators of the histamine H4 receptor - Google Patents
Benzofuro- and benzothienopyrimidine modulators of the histamine H4 receptorInfo
- Publication number
- NO20090268L NO20090268L NO20090268A NO20090268A NO20090268L NO 20090268 L NO20090268 L NO 20090268L NO 20090268 A NO20090268 A NO 20090268A NO 20090268 A NO20090268 A NO 20090268A NO 20090268 L NO20090268 L NO 20090268L
- Authority
- NO
- Norway
- Prior art keywords
- benzofuro
- receptor
- benzothienopyrimidine
- modulators
- histamine
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
- C07D491/147—Ortho-condensed systems the condensed system containing one ring with oxygen as ring hetero atom and two rings with nitrogen as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Transplantation (AREA)
- Agronomy & Crop Science (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Otolaryngology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83019206P | 2006-07-11 | 2006-07-11 | |
PCT/US2007/015763 WO2008008359A2 (en) | 2006-07-11 | 2007-07-10 | Benzofuro-and benzothienopyryimidine modulators of the histamine h4 receptor |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20090268L true NO20090268L (no) | 2009-03-06 |
Family
ID=38923848
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20090268A NO20090268L (no) | 2006-07-11 | 2009-01-16 | Benzofuro- and benzothienopyrimidine modulators of the histamine H4 receptor |
Country Status (24)
Country | Link |
---|---|
US (2) | US7576092B2 (xx) |
EP (1) | EP2040549B1 (xx) |
JP (1) | JP5352458B2 (xx) |
KR (1) | KR20090028819A (xx) |
CN (1) | CN101511190A (xx) |
AR (1) | AR061891A1 (xx) |
AU (1) | AU2007272956B2 (xx) |
BR (1) | BRPI0715452A2 (xx) |
CA (1) | CA2657908A1 (xx) |
CL (1) | CL2007002007A1 (xx) |
CO (1) | CO6150182A2 (xx) |
CR (1) | CR10609A (xx) |
EA (1) | EA015344B1 (xx) |
EC (1) | ECSP099061A (xx) |
ES (1) | ES2441958T3 (xx) |
IL (1) | IL196448A0 (xx) |
MX (1) | MX2009000457A (xx) |
MY (1) | MY145349A (xx) |
NO (1) | NO20090268L (xx) |
PE (1) | PE20080520A1 (xx) |
TW (1) | TW200821315A (xx) |
UY (1) | UY30479A1 (xx) |
WO (1) | WO2008008359A2 (xx) |
ZA (1) | ZA200900959B (xx) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101460483B (zh) | 2006-03-31 | 2013-05-08 | 詹森药业有限公司 | 作为组胺h4受体调节剂的苯并咪唑-2-基嘧啶和吡嗪 |
CL2008000467A1 (es) | 2007-02-14 | 2008-08-22 | Janssen Pharmaceutica Nv | Compuestos derivados de 2-aminopirimidina, moduladores del receptor histamina h4; su procedimiento de preparacion; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar un trastorno inflamatorio seleccionado de alegia, asma |
WO2009081222A1 (en) * | 2007-12-21 | 2009-07-02 | Glenmark Pharmaceuticals, S.A. | Substituted tricyclic pyridine or pyrimidine vanilloid receptor ligands |
PE20110052A1 (es) | 2008-06-12 | 2011-01-31 | Janssen Pharmaceutica Nv | Uso de un antagonista h4 de histamina para el tratamiento de adherencias postoperatorias |
US9371311B2 (en) | 2008-06-30 | 2016-06-21 | Janssen Pharmaceutica Nv | Benzoimidazol-2-yl pyrimidine derivatives |
WO2010064705A1 (ja) * | 2008-12-05 | 2010-06-10 | 大日本住友製薬株式会社 | H4受容体アンタゴニスト作用を有する新規7位置換ジヒドロピラノピリミジン誘導体 |
WO2010075270A1 (en) | 2008-12-22 | 2010-07-01 | Incyte Corporation | 4, 6-disubstituted 2-amino-pyrimidines as histamine h4 receptor modulators |
EP2201982A1 (en) | 2008-12-24 | 2010-06-30 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Histamine H4 receptor antagonists for the treatment of vestibular disorders |
IT1393337B1 (it) | 2009-03-06 | 2012-04-20 | Italiana Sint Spa | Sintesi di (4as, 7as)-ottaidro-1h-pirrolo[3,4-b]piridina |
US8481732B2 (en) | 2009-03-20 | 2013-07-09 | Incyte Corporation | Substituted heterocyclic compounds |
EP2671883A1 (en) | 2012-06-05 | 2013-12-11 | Bioprojet | New 6,11-dihydro-5H-benzo[d]imidazo[1,2-a]azepines derivatives as histamine H4 receptor ligands |
EP2858647B1 (en) | 2012-06-08 | 2018-05-23 | Sensorion | H4 receptor inhibitors for treating tinnitus |
CN102875558A (zh) * | 2012-11-05 | 2013-01-16 | 贵州大学 | 2-氯-4-取代-8-硝基苯并呋喃[3,2-d]嘧啶类化合物及其制备方法和用途 |
SI2964229T1 (sl) | 2013-03-06 | 2020-02-28 | Janssen Pharmaceutica Nv | Benzoimidazol-2-il pirimidin modulatorji receptorja histamina H4 |
EP3409662A4 (en) * | 2016-01-29 | 2019-08-28 | Meiji Seika Pharma Co., Ltd. | NOVEL CONNECTION AND PHARMACEUTICALLY COMPATIBLE SALT OF WHICH |
WO2020142729A1 (en) * | 2019-01-04 | 2020-07-09 | BellBrook Labs | Inhibitors of cgas activity as therapeutic agents |
EP4291188A1 (en) * | 2021-02-11 | 2023-12-20 | Bellbrook Labs, Llc | Inhibitors of cgas activity as therapeutic agents |
CN116589472A (zh) * | 2023-05-22 | 2023-08-15 | 郑州大学 | 一种苯并呋喃[3,2-d]并嘧啶-2-胺类化合物及其制备方法和应用 |
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JPH06220059A (ja) * | 1993-01-28 | 1994-08-09 | Tanabe Seiyaku Co Ltd | 縮合ピリミジン誘導体及びその製法 |
EP0724572B1 (en) | 1993-09-15 | 1998-12-16 | MERCK SHARP & DOHME LTD. | Fused tricyclic heteroaromatic derivatives as dopamine receptor subtype ligands |
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WO2005067546A2 (en) | 2004-01-13 | 2005-07-28 | Ambit Biosciences Corporation | Pyrrolopyrimidine derivatives and analogs and their use in the treatment and prevention of diseases |
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WO2007090853A1 (en) | 2006-02-10 | 2007-08-16 | Cellzome (Uk) Ltd. | Enantiomers of amino pyrimidine compounds for the treatment of inflammatory disorders |
EP1829879A1 (en) | 2006-02-10 | 2007-09-05 | Cellzome (UK) Ltd. | Amino pyrimidine compounds for the treatment of inflammatory disorders |
WO2007090854A1 (en) | 2006-02-10 | 2007-08-16 | Cellzome (Uk) Ltd. | Azetidine amino pyrimidine compounds for the treatment of inflammatory disorders |
WO2008074445A1 (en) | 2006-12-18 | 2008-06-26 | Ucb Pharma, S.A. | Novel tricyclic and heterotricyclic derivatives, processes for preparing them, pharmaceutical compositions thereof |
WO2009068512A1 (en) | 2007-11-30 | 2009-06-04 | Palau Pharma, S. A. | 2 -amino-pyrimidine derivatives as histamine h4 antagonists |
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Also Published As
Publication number | Publication date |
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TW200821315A (en) | 2008-05-16 |
KR20090028819A (ko) | 2009-03-19 |
MY145349A (en) | 2012-01-31 |
CR10609A (es) | 2009-06-04 |
EP2040549A4 (en) | 2010-09-08 |
US20080015200A1 (en) | 2008-01-17 |
ES2441958T3 (es) | 2014-02-07 |
CN101511190A (zh) | 2009-08-19 |
AU2007272956A1 (en) | 2008-01-17 |
ECSP099061A (es) | 2009-02-27 |
IL196448A0 (en) | 2009-11-18 |
AR061891A1 (es) | 2008-10-01 |
CL2007002007A1 (es) | 2008-08-22 |
PE20080520A1 (es) | 2008-06-13 |
AU2007272956B2 (en) | 2013-05-02 |
US20090325927A1 (en) | 2009-12-31 |
BRPI0715452A2 (pt) | 2013-03-05 |
CO6150182A2 (es) | 2010-04-20 |
EA200970113A1 (ru) | 2009-06-30 |
JP5352458B2 (ja) | 2013-11-27 |
CA2657908A1 (en) | 2008-01-17 |
ZA200900959B (en) | 2010-04-28 |
EP2040549B1 (en) | 2013-10-23 |
MX2009000457A (es) | 2009-01-27 |
US8030321B2 (en) | 2011-10-04 |
JP2009543775A (ja) | 2009-12-10 |
US7576092B2 (en) | 2009-08-18 |
EP2040549A2 (en) | 2009-04-01 |
EA015344B1 (ru) | 2011-06-30 |
WO2008008359A3 (en) | 2008-12-31 |
WO2008008359A2 (en) | 2008-01-17 |
UY30479A1 (es) | 2008-01-31 |
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