NO20085332L - Duloksetinhydrogenklorid-formuleringer med forsinket frigivelse - Google Patents
Duloksetinhydrogenklorid-formuleringer med forsinket frigivelseInfo
- Publication number
- NO20085332L NO20085332L NO20085332A NO20085332A NO20085332L NO 20085332 L NO20085332 L NO 20085332L NO 20085332 A NO20085332 A NO 20085332A NO 20085332 A NO20085332 A NO 20085332A NO 20085332 L NO20085332 L NO 20085332L
- Authority
- NO
- Norway
- Prior art keywords
- hydrogen chloride
- delayed release
- duloxetine
- chloride formulations
- layer
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- ZEUITGRIYCTCEM-KRWDZBQOSA-N (S)-duloxetine Chemical compound C1([C@@H](OC=2C3=CC=CC=C3C=CC=2)CCNC)=CC=CS1 ZEUITGRIYCTCEM-KRWDZBQOSA-N 0.000 title abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 title abstract 2
- 230000003111 delayed effect Effects 0.000 title abstract 2
- 229960002866 duloxetine Drugs 0.000 title abstract 2
- 229910000041 hydrogen chloride Inorganic materials 0.000 title abstract 2
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 title abstract 2
- 239000010410 layer Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229960002496 duloxetine hydrochloride Drugs 0.000 abstract 1
- 239000012055 enteric layer Substances 0.000 abstract 1
- 229920003132 hydroxypropyl methylcellulose phthalate Polymers 0.000 abstract 1
- 229940031704 hydroxypropyl methylcellulose phthalate Drugs 0.000 abstract 1
- 229920003145 methacrylic acid copolymer Polymers 0.000 abstract 1
- 229940117841 methacrylic acid copolymer Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- JFTURWWGPMTABQ-UHFFFAOYSA-N n,n-dimethyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine Chemical compound C=1C=CC2=CC=CC=C2C=1OC(CCN(C)C)C1=CC=CS1 JFTURWWGPMTABQ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
Abstract
Formuleringer med forsinket frigivelse av duloksetinhydrogenklorid og fremgangsmåter for fremstilling av slike er beskrevet. En foretrukket formulering innbefatter en inert kjerne, et legemiddellag omfattende duloksetinhydrogenklorid, et skillelag og et enterisk lag som omfatter minst én av metakrylsyrekopolymer og hydroksypropylmetylcelluloseftalat.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80284906P | 2006-05-22 | 2006-05-22 | |
PCT/US2007/012387 WO2007139886A2 (en) | 2006-05-22 | 2007-05-22 | Duloxetine hydrochloride delayed release formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20085332L true NO20085332L (no) | 2008-12-19 |
Family
ID=38779216
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20085332A NO20085332L (no) | 2006-05-22 | 2008-12-19 | Duloksetinhydrogenklorid-formuleringer med forsinket frigivelse |
Country Status (12)
Country | Link |
---|---|
US (1) | US20070292511A1 (no) |
EP (1) | EP1919467A2 (no) |
JP (1) | JP2009538315A (no) |
KR (1) | KR20090005237A (no) |
CN (1) | CN101448493A (no) |
BR (1) | BRPI0711606A2 (no) |
CA (1) | CA2651716A1 (no) |
IL (1) | IL194877A0 (no) |
MX (1) | MX2008014758A (no) |
NO (1) | NO20085332L (no) |
RU (1) | RU2008148547A (no) |
WO (1) | WO2007139886A2 (no) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008020286A2 (en) * | 2006-08-14 | 2008-02-21 | Torrent Pharmaceuticals Limited | Pharmaceutical compositions of duloxetine |
US20100172972A1 (en) * | 2007-05-21 | 2010-07-08 | Sun Pharmaceutical Industries Limited | Enteric coated pharmaceutical compositions |
GB0712220D0 (en) * | 2007-06-23 | 2007-08-01 | Arrow Int Ltd | Duloxetine formulation |
WO2009066181A2 (en) * | 2007-07-09 | 2009-05-28 | Combino Pharm, S.L. | Oral delayed-release duloxentine hydrochloride pellets |
US20090017113A1 (en) * | 2007-07-13 | 2009-01-15 | Osinga Niels J | Duloxetine formulations |
JP2011510024A (ja) * | 2008-01-25 | 2011-03-31 | アルファファーム ピーティーワイ リミテッド | デュロキセチンの遅延放出医薬組成物 |
US20110020439A1 (en) * | 2008-03-24 | 2011-01-27 | Shrenik Annasaheb Kole | Delayed release compositions of duloxetine |
EP2133072A1 (en) | 2008-06-13 | 2009-12-16 | KRKA, D.D., Novo Mesto | Gastro-resistant pharmaceutical oral compositions comprising duloxetine or its pharmaceutically acceptable derivatives |
EA201001871A1 (ru) * | 2008-06-13 | 2011-08-30 | Крка, Д.Д. Ново Место | Гастрорезистентные пероральные фармацевтические композиции, содержащие дулоксетин или его фармацевтически приемлемые производные |
US20100040680A1 (en) * | 2008-08-15 | 2010-02-18 | Felix Lai | Multiparticulate selective serotonin and norepinephrine reuptake inhibitor formulation |
ES2376095B1 (es) * | 2008-10-02 | 2013-01-24 | Laboratorios Del Dr. Esteve, S.A. | Pellets entéricos de duloxetina. |
WO2010078878A1 (en) * | 2009-01-12 | 2010-07-15 | Synthon B.V. | Duloxetine formulations |
DE102009033621A1 (de) | 2009-07-17 | 2011-01-20 | Add Technologies Ltd. | Trennschichten für pharmazeutische Zubereitungen zur Verhinderung von Wechselwirkungen zwischen Arzneistoffen und pharmazeutisch-technologischen Hilfsstoffen |
CA2792523C (en) * | 2010-03-09 | 2018-01-09 | Alkermes Pharma Ireland Limited | Alcohol resistant enteric pharmaceutical compositions |
EP2377525A1 (en) | 2010-03-26 | 2011-10-19 | Laboratorios del Dr. Esteve S.A. | Duloxetine enteric pellets |
WO2013045352A1 (de) * | 2011-09-30 | 2013-04-04 | Basf Se | Verfahren zur herstellung von festen pigmenthaltigen filmüberzugsmitteln in form von granulaten auf basis von magensaftresistenten filmbildnern für pharmazeutische dosierungsformen |
EP2916824B1 (en) | 2012-11-12 | 2019-06-19 | New Jersey Institute of Technology | Pharmaceutical core-shell composite powder and processes for making the same |
CN103127023B (zh) * | 2013-03-01 | 2014-08-27 | 河北天成药业股份有限公司 | 一种盐酸度洛西汀肠溶片及其制备方法 |
CN103211777A (zh) * | 2013-03-31 | 2013-07-24 | 北京万全阳光医学技术有限公司 | 一种盐酸度洛西汀的药物制剂及其制备的方法 |
CN103393615B (zh) * | 2013-07-24 | 2015-07-15 | 海南华益泰康药业有限公司 | 一种度洛西汀肠溶小丸及其制备方法 |
PL224543B1 (pl) | 2013-08-21 | 2017-01-31 | Pabianickie Zakłady Farm Polfa Spółka Akcyjna | Dojelitowa tabletka duloksetyny |
JP6815109B2 (ja) * | 2016-06-23 | 2021-01-20 | キョーリンリメディオ株式会社 | デュロキセチンまたは薬学的に許容されるその塩を有効成分とする医薬組成物 |
JP6866136B2 (ja) * | 2016-11-30 | 2021-04-28 | 共和薬品工業株式会社 | デュロキセチン塩酸塩を含む口腔内崩壊錠 |
US9839626B1 (en) | 2016-12-14 | 2017-12-12 | Sun Pharmaceutical Industries Limited | Duloxetine sprinkles |
JP2018154590A (ja) * | 2017-03-17 | 2018-10-04 | 沢井製薬株式会社 | デュロキセチン腸溶性顆粒およびデュロキセチン腸溶性製剤 |
JP7072431B2 (ja) * | 2017-04-14 | 2022-05-20 | 富士化学工業株式会社 | 錠剤及びその製造方法 |
JP6972674B2 (ja) * | 2017-06-06 | 2021-11-24 | ニプロ株式会社 | 経口医薬製剤 |
JP2019081753A (ja) * | 2017-10-30 | 2019-05-30 | 大原薬品工業株式会社 | デュロキセチン塩酸塩の溶出性が改善された腸溶性製剤 |
WO2019157066A1 (en) * | 2018-02-06 | 2019-08-15 | Robert Niichel | A multiparticulate including pharmaceutical or probiotic active ingredients |
CN112566668A (zh) * | 2018-06-22 | 2021-03-26 | 快力胶囊股份有限公司 | 肠溶性硬胶囊 |
JP2020029447A (ja) * | 2018-06-25 | 2020-02-27 | 大原薬品工業株式会社 | 腸溶性高分子及び抗付着剤を含有する顆粒 |
PL3628311T3 (pl) * | 2018-09-27 | 2021-07-05 | Inibsa Ginecologia, S.A. | Sposób wytwarzania doustnej wielojednostkowej postaci dawkowanej bursztynianu doksylaminy i chlorowodorku pirydoksyny o zmodyfikowanym uwalnianiu |
CN112168797A (zh) * | 2020-10-14 | 2021-01-05 | 宁波高新区美诺华医药创新研究院有限公司 | 度洛西汀药物组合物 |
WO2022115054A1 (en) * | 2020-11-27 | 2022-06-02 | Santa Farma Ilac Sanayii A.S. | Enteric coated duloxetine compositions |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5508276A (en) * | 1994-07-18 | 1996-04-16 | Eli Lilly And Company | Duloxetine enteric pellets |
US5910319A (en) * | 1997-05-29 | 1999-06-08 | Eli Lilly And Company | Fluoxetine enteric pellets and methods for their preparation and use |
US20040132826A1 (en) * | 2002-10-25 | 2004-07-08 | Collegium Pharmaceutical, Inc. | Modified release compositions of milnacipran |
EP1424079A1 (en) * | 2002-11-27 | 2004-06-02 | Boehringer Ingelheim International GmbH | Combination of a beta-3-receptor agonist and of a reuptake inhibitor of serotonin and/or norepinephrine |
EP1699458A4 (en) * | 2003-12-30 | 2012-04-25 | Reddys Lab Ltd Dr | PHARMACEUTICAL COMPOSITION |
GB0410470D0 (en) * | 2004-05-11 | 2004-06-16 | Cipla Ltd | Pharmaceutical compound and polymorphs thereof |
JP2008543929A (ja) * | 2005-06-20 | 2008-12-04 | カディラ・ヘルスケア・リミテッド | デュロキセチンの調節放出型の投与製剤 |
US20060165776A1 (en) * | 2005-08-31 | 2006-07-27 | Ramesh Sesha | Antidepressant oral pharmaceutical compositions |
-
2007
- 2007-05-22 WO PCT/US2007/012387 patent/WO2007139886A2/en active Application Filing
- 2007-05-22 KR KR1020087029566A patent/KR20090005237A/ko not_active Application Discontinuation
- 2007-05-22 CN CNA200780018648XA patent/CN101448493A/zh active Pending
- 2007-05-22 MX MX2008014758A patent/MX2008014758A/es not_active Application Discontinuation
- 2007-05-22 RU RU2008148547/15A patent/RU2008148547A/ru not_active Application Discontinuation
- 2007-05-22 BR BRPI0711606-3A patent/BRPI0711606A2/pt not_active IP Right Cessation
- 2007-05-22 EP EP07795287A patent/EP1919467A2/en not_active Withdrawn
- 2007-05-22 US US11/805,395 patent/US20070292511A1/en not_active Abandoned
- 2007-05-22 JP JP2009512149A patent/JP2009538315A/ja active Pending
- 2007-05-22 CA CA002651716A patent/CA2651716A1/en not_active Abandoned
-
2008
- 2008-10-23 IL IL194877A patent/IL194877A0/en unknown
- 2008-12-19 NO NO20085332A patent/NO20085332L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
MX2008014758A (es) | 2009-01-19 |
EP1919467A2 (en) | 2008-05-14 |
CN101448493A (zh) | 2009-06-03 |
RU2008148547A (ru) | 2010-06-27 |
BRPI0711606A2 (pt) | 2012-02-14 |
KR20090005237A (ko) | 2009-01-12 |
WO2007139886A2 (en) | 2007-12-06 |
US20070292511A1 (en) | 2007-12-20 |
CA2651716A1 (en) | 2007-12-06 |
JP2009538315A (ja) | 2009-11-05 |
WO2007139886A3 (en) | 2008-03-13 |
IL194877A0 (en) | 2009-08-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |