NO20082345L - Selektive VPAC2 reseptorpeptidagonister - Google Patents
Selektive VPAC2 reseptorpeptidagonisterInfo
- Publication number
- NO20082345L NO20082345L NO20082345A NO20082345A NO20082345L NO 20082345 L NO20082345 L NO 20082345L NO 20082345 A NO20082345 A NO 20082345A NO 20082345 A NO20082345 A NO 20082345A NO 20082345 L NO20082345 L NO 20082345L
- Authority
- NO
- Norway
- Prior art keywords
- vpac2 receptor
- receptor peptide
- peptide agonists
- selective vpac2
- selective
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Electric Propulsion And Braking For Vehicles (AREA)
- Conductive Materials (AREA)
- Harvester Elements (AREA)
Abstract
Den foreliggende oppfinnelsen omslutter peptider som selektivt aktiverer VPAC2 reseptoren og er nyttige i behandlingen av diabetes.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73029105P | 2005-10-26 | 2005-10-26 | |
US74034205P | 2005-11-29 | 2005-11-29 | |
US74336406P | 2006-02-28 | 2006-02-28 | |
PCT/US2006/041550 WO2007050651A1 (en) | 2005-10-26 | 2006-10-24 | Selective vpac2 receptor peptide agonists |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20082345L true NO20082345L (no) | 2008-05-23 |
Family
ID=37716005
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20082345A NO20082345L (no) | 2005-10-26 | 2008-05-23 | Selektive VPAC2 reseptorpeptidagonister |
Country Status (12)
Country | Link |
---|---|
US (2) | US7582608B2 (no) |
EP (1) | EP1942941A1 (no) |
JP (1) | JP2009519212A (no) |
KR (1) | KR101057284B1 (no) |
CN (1) | CN101296708B (no) |
AU (1) | AU2006306236B2 (no) |
BR (1) | BRPI0617740A2 (no) |
CA (1) | CA2627716A1 (no) |
EA (1) | EA012930B1 (no) |
IL (1) | IL189922A0 (no) |
NO (1) | NO20082345L (no) |
WO (1) | WO2007050651A1 (no) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10328316A1 (de) | 2003-06-23 | 2005-01-20 | Grünenthal GmbH | Verfahren zur Herstellung von Dimethyl-(3-aryl-buthyl)-aminverbindungen als pharmazeutische Wirkstoffe |
CA2577010A1 (en) * | 2004-08-18 | 2006-03-02 | Eli Lilly And Company | Selective vpac2 receptor peptide agonists |
US20090170775A1 (en) * | 2004-10-08 | 2009-07-02 | Transition Therapeutics, Inc. | Vasoactive intestinal polypeptide compositions |
US7595294B2 (en) | 2004-10-08 | 2009-09-29 | Transition Therapeutics, Inc. | Vasoactive intestinal polypeptide pharmaceuticals |
DE102005052588A1 (de) * | 2005-11-02 | 2007-05-10 | Grünenthal GmbH | Verfahren zur Herstellung substituierter Dimethyl-(3-aryl-butyl)-amin-Verbindungen mittels homogener Katalyse |
US20130172274A1 (en) | 2005-12-20 | 2013-07-04 | Duke University | Methods and compositions for delivering active agents with enhanced pharmacological properties |
TWI496762B (zh) | 2006-07-24 | 2015-08-21 | 製備(1r,2r)-3-(3-二甲胺基-1-乙基-2-甲基-丙基)-酚之方法 | |
WO2009158704A2 (en) | 2008-06-27 | 2009-12-30 | Duke University | Therapeutic agents comprising elastin-like peptides |
EP2464370B1 (en) * | 2009-08-14 | 2017-03-29 | Phasebio Pharmaceuticals, Inc. | Modified vasoactive intestinal peptides |
CN102822175A (zh) * | 2009-12-18 | 2012-12-12 | 埃迪尼克斯医药公司 | 5,5-稠合的亚芳基或亚杂芳基丙型肝炎病毒抑制剂 |
CA2873553C (en) | 2011-06-06 | 2020-01-28 | Phasebio Pharmaceuticals, Inc. | Use of modified vasoactive intestinal peptides in the treatment of hypertension |
EP3139949B1 (en) | 2014-05-08 | 2020-07-29 | Phasebio Pharmaceuticals, Inc. | Compositions comprising a vip-elp fusion protein for use in treating cystic fibrosis |
CA2976038A1 (en) | 2015-02-09 | 2016-08-18 | Phasebio Pharmaceuticals, Inc. | Methods and compositions for treating muscle disease and disorders |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04193896A (ja) | 1989-10-26 | 1992-07-13 | Meiji Seika Kaisha Ltd | 活性ペプチド |
JPH0692991A (ja) | 1991-02-28 | 1994-04-05 | Daicel Chem Ind Ltd | 新規活性ペプチド |
WO1998002453A2 (en) | 1996-07-15 | 1998-01-22 | Universite Libre De Bruxelles | Peptidic ligands having a higher selectivity for the vip1 receptor than for the vip2 receptor |
US6242563B1 (en) | 1998-07-20 | 2001-06-05 | Societe De Conseils De Recherches Et D'applications Scientifiques, Sas | Peptide analogues |
PL345583A1 (en) | 1998-07-20 | 2001-12-17 | Sod Conseils Rech Applic | Peptide analogues of pacap |
US20030087820A1 (en) * | 1999-01-14 | 2003-05-08 | Young Andrew A. | Novel exendin agonist formulations and methods of administration thereof |
AU775063C (en) | 1999-04-30 | 2005-05-12 | Amylin Pharmaceuticals, Inc. | Modified exendins and exendin agonists |
ES2307534T3 (es) | 1999-09-28 | 2008-12-01 | Bayer Corporation | Agonistas de receptores 3 (r3) del peptido activador de la adenilato ciclasa hipofisiaria (pacap) y sus metodos de uso farmacologicos. |
WO2003058203A2 (en) | 2002-01-08 | 2003-07-17 | Eli Lilly And Company | Extended glucagon-like peptide-1 analogs |
US7378494B2 (en) | 2002-07-12 | 2008-05-27 | Bayer Healthcare Ag | Pituitary adenylate cyclase activating peptide (PACAP) receptor (VPAC2) agonist peptide |
BRPI0407936A (pt) * | 2003-03-19 | 2006-02-21 | Lilly Co Eli | composto de glp-1 peguilado, método de estimular o receptor de glp-1 em um indivìduo, e, uso de composto glp-1 peguilado |
ATE461217T1 (de) | 2003-12-18 | 2010-04-15 | Novo Nordisk As | Glp-1-verbindungen |
AU2005208911A1 (en) * | 2004-01-27 | 2005-08-11 | Bayer Healthcare Llc | Pituitary adenylate cyclase activating peptide (PACAP) receptor (VPAC2) agonists and their pharmacological methods of use |
WO2005113594A1 (en) * | 2004-05-21 | 2005-12-01 | Eli Lilly And Company | Selective vpac2 receptor peptide agonists |
CA2567635A1 (en) * | 2004-05-21 | 2005-12-01 | Eli Lilly And Company | Selective vpac2 receptor peptide agonists |
CA2577010A1 (en) * | 2004-08-18 | 2006-03-02 | Eli Lilly And Company | Selective vpac2 receptor peptide agonists |
AU2005294125A1 (en) | 2004-10-08 | 2006-04-20 | Transition Therapeutics Inc. | Vasoactive intestinal polypeptide pharmaceuticals |
WO2008043102A2 (en) | 2006-10-06 | 2008-04-10 | Transition Therapeutics Inc. | Vasoactive intestinal polypeptide compositions |
US7595294B2 (en) | 2004-10-08 | 2009-09-29 | Transition Therapeutics, Inc. | Vasoactive intestinal polypeptide pharmaceuticals |
-
2006
- 2006-10-24 AU AU2006306236A patent/AU2006306236B2/en not_active Expired - Fee Related
- 2006-10-24 EP EP06817361A patent/EP1942941A1/en not_active Withdrawn
- 2006-10-24 BR BRPI0617740-9A patent/BRPI0617740A2/pt not_active IP Right Cessation
- 2006-10-24 WO PCT/US2006/041550 patent/WO2007050651A1/en active Application Filing
- 2006-10-24 US US12/090,656 patent/US7582608B2/en not_active Expired - Fee Related
- 2006-10-24 CA CA002627716A patent/CA2627716A1/en not_active Abandoned
- 2006-10-24 CN CN2006800398953A patent/CN101296708B/zh not_active Expired - Fee Related
- 2006-10-24 JP JP2008537892A patent/JP2009519212A/ja active Pending
- 2006-10-24 EA EA200801180A patent/EA012930B1/ru not_active IP Right Cessation
- 2006-10-24 KR KR1020087010055A patent/KR101057284B1/ko not_active IP Right Cessation
-
2008
- 2008-03-04 IL IL189922A patent/IL189922A0/en unknown
- 2008-05-23 NO NO20082345A patent/NO20082345L/no not_active Application Discontinuation
-
2009
- 2009-07-24 US US12/508,584 patent/US7897573B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
KR101057284B1 (ko) | 2011-08-16 |
EA200801180A1 (ru) | 2008-08-29 |
JP2009519212A (ja) | 2009-05-14 |
AU2006306236A1 (en) | 2007-05-03 |
EA012930B1 (ru) | 2010-02-26 |
BRPI0617740A2 (pt) | 2011-08-02 |
CN101296708B (zh) | 2011-12-07 |
IL189922A0 (en) | 2008-08-07 |
US20080234198A1 (en) | 2008-09-25 |
AU2006306236B2 (en) | 2011-12-01 |
CN101296708A (zh) | 2008-10-29 |
KR20080053393A (ko) | 2008-06-12 |
US20100009916A1 (en) | 2010-01-14 |
WO2007050651A1 (en) | 2007-05-03 |
EP1942941A1 (en) | 2008-07-16 |
US7897573B2 (en) | 2011-03-01 |
US7582608B2 (en) | 2009-09-01 |
CA2627716A1 (en) | 2007-05-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |