NO20080671L - Bisykliske piperaziner som metabotrofiske glutamatreseptorantagonister - Google Patents

Bisykliske piperaziner som metabotrofiske glutamatreseptorantagonister

Info

Publication number
NO20080671L
NO20080671L NO20080671A NO20080671A NO20080671L NO 20080671 L NO20080671 L NO 20080671L NO 20080671 A NO20080671 A NO 20080671A NO 20080671 A NO20080671 A NO 20080671A NO 20080671 L NO20080671 L NO 20080671L
Authority
NO
Norway
Prior art keywords
receptor antagonists
glutamate receptor
piperazines
bicyclic
metabotrophic glutamate
Prior art date
Application number
NO20080671A
Other languages
English (en)
Norwegian (no)
Inventor
Abdelmalik Slassi
Tao Xin
Louise Edwards
Methvin Isaac
Guang-Ri Sun
Peter Dove
Alexander Minidis
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20080671L publication Critical patent/NO20080671L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20080671A 2005-08-15 2008-02-05 Bisykliske piperaziner som metabotrofiske glutamatreseptorantagonister NO20080671L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70794505P 2005-08-15 2005-08-15
PCT/US2006/030393 WO2007021574A1 (fr) 2005-08-15 2006-08-04 Piperazines bicycliques en tant qu'agents antagonistes de recepteur de glutamate metabotropique

Publications (1)

Publication Number Publication Date
NO20080671L true NO20080671L (no) 2008-03-04

Family

ID=37451264

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20080671A NO20080671L (no) 2005-08-15 2008-02-05 Bisykliske piperaziner som metabotrofiske glutamatreseptorantagonister

Country Status (16)

Country Link
US (2) US20080312240A1 (fr)
EP (1) EP1919911A1 (fr)
JP (1) JP2009504735A (fr)
KR (1) KR20080050392A (fr)
CN (1) CN101248071A (fr)
AR (1) AR055367A1 (fr)
AU (1) AU2006280232A1 (fr)
BR (1) BRPI0614480A2 (fr)
CA (1) CA2616308A1 (fr)
IL (1) IL188808A0 (fr)
MX (1) MX2008001607A (fr)
NO (1) NO20080671L (fr)
TW (1) TW200800204A (fr)
UY (1) UY29734A1 (fr)
WO (1) WO2007021574A1 (fr)
ZA (1) ZA200801034B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120029190A1 (en) * 2009-04-03 2012-02-02 Douglas Burdi Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof
FR2974365B1 (fr) * 2011-04-20 2017-08-25 Centre Nat De La Rech Scient (C N R S) 1,2,3-triazoles 1,4-disubstituees, leurs procedes de preparation et leurs utilisations diagnostiques et therapeutiques
WO2014066435A1 (fr) 2012-10-22 2014-05-01 City Of Hope Dérivés d'étoposide
RU2019106494A (ru) 2016-08-10 2020-09-14 Байер Кропсайенс Акциенгезельшафт Замещенные 2-гетероциклил-имидазолил-карбоксамиды в качестве средств для борьбы с вредителями
CA3036852A1 (fr) 2016-09-15 2018-03-22 City Of Hope Derives dithio etp
CN114907258B (zh) * 2021-02-09 2023-04-11 中国科学院化学研究所 一种钯与氮杂环卡宾协同催化制备炔丙基酮类化合物的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040132726A1 (en) * 2002-08-09 2004-07-08 Astrazeneca Ab And Nps Pharmaceuticals, Inc. New compounds
EP1615904B1 (fr) * 2003-04-15 2008-02-27 AstraZeneca AB Benzensulphonamides substituées comme potentiateurs des récepteurs du glutamate
WO2005077373A2 (fr) * 2004-02-03 2005-08-25 Astrazeneca Ab Nouveau traitement du reflux gastro-oesophagien pathologique ii

Also Published As

Publication number Publication date
US20080312240A1 (en) 2008-12-18
CA2616308A1 (fr) 2007-02-22
AR055367A1 (es) 2007-08-22
UY29734A1 (es) 2007-02-28
CN101248071A (zh) 2008-08-20
TW200800204A (en) 2008-01-01
IL188808A0 (en) 2008-08-07
AU2006280232A1 (en) 2007-02-22
MX2008001607A (es) 2008-04-14
WO2007021574A1 (fr) 2007-02-22
US20070037816A1 (en) 2007-02-15
EP1919911A1 (fr) 2008-05-14
JP2009504735A (ja) 2009-02-05
ZA200801034B (en) 2008-12-31
KR20080050392A (ko) 2008-06-05
BRPI0614480A2 (pt) 2017-06-06

Similar Documents

Publication Publication Date Title
MX2008001606A (es) Piperazinas substituidas como antagonistas de receptor de glutamato metabotropico.
MXPA06009475A (es) Derivados de quinazolina y usos terapeuticos de los mismos.
HK1120725A1 (en) Tetrahydro-beta-carbolin-sulfonamide derivatives as 5-ht6ligands
MY148429A (en) Novel 1,4-benzothiepin-1,1-dioxide derivatives which are substituted with benzyl groups, method for producing drugs containing said compounds and use thereof
EA200701324A1 (ru) Соединения пиридина для лечения заболеваний, опосредованных действием простагландина
GEP20094727B (en) Oxyindole derivatives as 5ht4 receptor agonists
ATE397605T1 (de) Nebivolol und dessen pharmazeutisch unbedenkliche salze, herstellungsverfahren und pharmazeutische zusammensetzungen von nebivolol
NO20071137L (no) Nye piperidinderivater for behandling av depresjon
MX2007006387A (es) Derivados de piridina 3-substituidos como antagonistas h3.
MY130803A (en) New quinuclidine amide derivatives
TW200800943A (en) Indane derivatives as MCH receptor antagonists
HK1104174A1 (en) Glucagon receptor antagonists, preparation and therapeutic uses
ATE459619T1 (de) Glucagonrezeptorantagonisten, deren herstellung und therapeutische verwendung
NO20082445L (no) Neuropeptid-2 reseptor-agonister
NO20076695L (no) Nye MCHR1-antagonister og deres anvendelse for behandling av MCHR1-medierte tilstander og forstyrrelser
TW200626158A (en) Naphthaline derivatives
WO2008077557A8 (fr) Dérivés 8-éthynylxanthine en tant qu'antagonistes sélectifs du récepteur 2a
MX2007007027A (es) Derivados piperazinilpiridina como agentes anti-obesidad.
TW200637817A (en) 5-aminoindole derivatives
ATE473961T1 (de) Glucagonrezeptorantagonisten, deren herstellung und therapeutische verwendung
NO20080671L (no) Bisykliske piperaziner som metabotrofiske glutamatreseptorantagonister
NO20080669L (no) Acetylenpiperaziner som metabotrofiske glutamatreseptorantagonister
ATE523488T1 (de) Histamin-h3-rezeptor-mittel, deren herstellung und therapeutische verwendung
BRPI0517734A (pt) derivados de 1-[(6,7-alcoxiquinoxalinil substituìdo) aminocarbonil]-4- (hetero) arilpiperazina
MX2009005242A (es) Derivados de 3-(hetero)arilisoquinolinamida sustituida en posición 5, 6 o 7 y uso terapeutico del mismo.

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application