NO20075044L - Nytt salt av kinuclidinderivat - Google Patents

Nytt salt av kinuclidinderivat

Info

Publication number
NO20075044L
NO20075044L NO20075044A NO20075044A NO20075044L NO 20075044 L NO20075044 L NO 20075044L NO 20075044 A NO20075044 A NO 20075044A NO 20075044 A NO20075044 A NO 20075044A NO 20075044 L NO20075044 L NO 20075044L
Authority
NO
Norway
Prior art keywords
acid
pharmaceutical
tartaric
active ingredient
fresh salt
Prior art date
Application number
NO20075044A
Other languages
English (en)
Inventor
Ken Ikeda
Masahiro Hayakawa
Kiyohiro Samizu
Hiroshi Uebayashi
Makoto Takeuchi
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of NO20075044L publication Critical patent/NO20075044L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/472—Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/08—Mydriatics or cycloplegics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Otolaryngology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Et syreaddisjonssalt dannet fra (-)-(1R)-1-fenyl-1,2,3,4-tetrahydroisokinolin-2-karboksylsyre-(3R)-kinuklidin-3-yl-ester og en syre valgt fra gruppen bestående av (-)-(2S,3S)-vinsyre, (+)(2S,3S)-di-o-benzoyl-vinsyre, (+)-(2S,3S)-di-o(4-metylbenzoyl)vinsyre, (-)-L-fenylalanin, benzensulfonsyre, sykloheksansulfamsyre, hydrobromsyre, naftalen-2-sulfonsyre, sebacinsyre, (+)-kamfer-10-sulfonsyre, p-toluensulfonsyre, etansulfonsyre, metansulfonsyre og metylfosfat. Dette salt viser ikke noe hygroskopisitet i et slikt nivå som ikke er ønskelig for anvendelse som et farmasøytisk middel eller en aktiv bestanddel av et farmasøytisk middel, og er derfor en uhyre anvendbar forbindelse for anvendelse som et farmasøytisk middel eller en aktiv bestanddel av et farmasøytisk middel.
NO20075044A 2005-03-08 2007-10-05 Nytt salt av kinuclidinderivat NO20075044L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2005063405 2005-03-08
JP2005088872A JP3701964B1 (ja) 2005-03-08 2005-03-25 キヌクリジン誘導体の新規な塩
PCT/JP2006/304241 WO2006095671A1 (ja) 2005-03-08 2006-03-06 キヌクリジン誘導体の新規な塩

Publications (1)

Publication Number Publication Date
NO20075044L true NO20075044L (no) 2007-12-05

Family

ID=34940702

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20075044A NO20075044L (no) 2005-03-08 2007-10-05 Nytt salt av kinuclidinderivat

Country Status (18)

Country Link
US (1) US7176219B2 (no)
EP (1) EP1700858B1 (no)
JP (2) JP3701964B1 (no)
KR (1) KR20070110128A (no)
AR (1) AR055741A1 (no)
AT (1) ATE396992T1 (no)
AU (1) AU2006221451A1 (no)
BR (1) BRPI0608843A2 (no)
CA (1) CA2599872A1 (no)
DE (1) DE602005007176D1 (no)
ES (1) ES2306030T3 (no)
IL (1) IL185470A0 (no)
NO (1) NO20075044L (no)
PL (1) PL1700858T3 (no)
PT (1) PT1700858E (no)
RU (1) RU2007137064A (no)
TW (1) TW200714599A (no)
WO (1) WO2006095671A1 (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100137358A1 (en) * 1996-11-05 2010-06-03 Dr. Reddy's Laboratories Ltd. Solifenacin compositions
EP1852117A4 (en) * 2005-02-25 2010-10-27 Astellas Pharma Inc PHARMACEUTICAL AGENT COMPRISING SOLIFENACIN
JP3701964B1 (ja) * 2005-03-08 2005-10-05 アステラス製薬株式会社 キヌクリジン誘導体の新規な塩
CZ300692B6 (cs) * 2006-12-22 2009-07-15 Zentiva, A. S. Zpusob prípravy solifenacinu
NZ586675A (en) * 2008-01-08 2012-04-27 Merck Sharp & Dohme Pharmaceutically acceptable salts of 2-{ 4-[(3s)-piperidin-3- yl]phenyl} -2h-indazole-7-carboxamide
SI3067353T1 (en) 2008-07-29 2018-03-30 Krka, D.D., Novo Mesto Process for the preparation of solifenacin salts and their inclusion in pharmaceutical dosage forms
US8278302B2 (en) 2009-04-08 2012-10-02 Boehringer Ingelheim International Gmbh Substituted piperidines as CCR3 antagonists
UA109290C2 (uk) * 2010-10-07 2015-08-10 Спільні кристали і солі інгібіторів ccr3
US10213421B2 (en) 2012-04-04 2019-02-26 Alkahest, Inc. Pharmaceutical formulations comprising CCR3 antagonists
US20150202212A1 (en) * 2012-07-31 2015-07-23 University Of Massachusetts Medical School Methods for identifying agents for treating smooth muscle disorders and compositions thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO2005012I1 (no) 1994-12-28 2005-06-06 Debio Rech Pharma Sa Triptorelin og farmasoytisk akseptable salter derav
GB9600063D0 (en) * 1996-01-03 1996-03-06 Fujisawa Pharmaceutical Co Guaridine derivatives
JPH107675A (ja) 1996-06-21 1998-01-13 Yamanouchi Pharmaceut Co Ltd 新規なイソキノリン誘導体又はその塩
JP2002104968A (ja) 2000-09-28 2002-04-10 Senju Pharmaceut Co Ltd 毛様体筋の緊張緩和剤
JP4174673B2 (ja) * 2001-07-10 2008-11-05 アステラス製薬株式会社 間質性膀胱炎治療用医薬組成物
JP3701964B1 (ja) 2005-03-08 2005-10-05 アステラス製薬株式会社 キヌクリジン誘導体の新規な塩

Also Published As

Publication number Publication date
CA2599872A1 (en) 2006-09-14
WO2006095671A1 (ja) 2006-09-14
RU2007137064A (ru) 2009-04-20
PL1700858T3 (pl) 2008-10-31
EP1700858B1 (en) 2008-05-28
US7176219B2 (en) 2007-02-13
PT1700858E (pt) 2008-07-17
AU2006221451A1 (en) 2006-09-14
AR055741A1 (es) 2007-09-05
US20060205770A1 (en) 2006-09-14
ATE396992T1 (de) 2008-06-15
KR20070110128A (ko) 2007-11-15
BRPI0608843A2 (pt) 2010-02-02
ES2306030T3 (es) 2008-11-01
JPWO2006095671A1 (ja) 2008-08-14
JP2008308406A (ja) 2008-12-25
DE602005007176D1 (de) 2008-07-10
EP1700858A1 (en) 2006-09-13
JP4605218B2 (ja) 2011-01-05
IL185470A0 (en) 2008-01-06
TW200714599A (en) 2007-04-16
JP3701964B1 (ja) 2005-10-05

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