NO20074623L - Fremgangsmate for peptidsyntese - Google Patents

Fremgangsmate for peptidsyntese

Info

Publication number
NO20074623L
NO20074623L NO20074623A NO20074623A NO20074623L NO 20074623 L NO20074623 L NO 20074623L NO 20074623 A NO20074623 A NO 20074623A NO 20074623 A NO20074623 A NO 20074623A NO 20074623 L NO20074623 L NO 20074623L
Authority
NO
Norway
Prior art keywords
peptide synthesis
thymosin
found
solid phase
phase synthesis
Prior art date
Application number
NO20074623A
Other languages
English (en)
Inventor
Fernando Albericio
Luis Javier Cruz
Ramos Yesica Garcia
Judit Tulla-Puche
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of NO20074623L publication Critical patent/NO20074623L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57581—Thymosin; Related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C07K17/08—Peptides being immobilised on, or in, an organic carrier the carrier being a synthetic polymer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6957—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a device or a kit, e.g. stents or microdevices
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

Abstract

En fremgangsmåte for fastfase syntese av Tymosin a1 er funnet.
NO20074623A 2005-05-04 2007-09-12 Fremgangsmate for peptidsyntese NO20074623L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05009758 2005-05-04
US69985105P 2005-07-18 2005-07-18
PCT/EP2006/004192 WO2006117227A2 (en) 2005-05-04 2006-05-04 Solid phase bound thymosin alpha-1 and its synthesis

Publications (1)

Publication Number Publication Date
NO20074623L true NO20074623L (no) 2007-12-03

Family

ID=36650882

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20074623A NO20074623L (no) 2005-05-04 2007-09-12 Fremgangsmate for peptidsyntese

Country Status (17)

Country Link
US (1) US20090171068A1 (no)
EP (1) EP1891104B1 (no)
JP (1) JP2008543733A (no)
KR (1) KR20080012884A (no)
CN (1) CN101166761A (no)
AT (1) ATE440856T1 (no)
AU (1) AU2006243344B2 (no)
CA (1) CA2600303A1 (no)
DE (1) DE602006008781D1 (no)
DK (1) DK1891104T3 (no)
ES (1) ES2332666T3 (no)
IL (1) IL186774A0 (no)
MX (1) MX2007013400A (no)
NO (1) NO20074623L (no)
PT (1) PT1891104E (no)
WO (1) WO2006117227A2 (no)
ZA (1) ZA200708110B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2288118B1 (es) * 2006-05-10 2008-11-01 Bcn Peptides, S.A. Procedimiento para sintetizar timosinas.
US8076295B2 (en) * 2007-04-17 2011-12-13 Nanotope, Inc. Peptide amphiphiles having improved solubility and methods of using same
WO2009075788A1 (en) * 2007-12-05 2009-06-18 Semprus Biociences Corporation Synthetic non-fouling amino acids
CN103242443A (zh) * 2012-02-06 2013-08-14 长春百克生物科技股份公司 一种胸腺素α1及其类似物的制备方法
US10087221B2 (en) 2013-03-21 2018-10-02 Sanofi-Aventis Deutschland Gmbh Synthesis of hydantoin containing peptide products
AU2014234314B2 (en) 2013-03-21 2018-02-15 Sanofi-Aventis Deutschland Gmbh Synthesis of cyclic imide containing peptide products
JPWO2016047794A1 (ja) * 2014-09-26 2017-09-28 株式会社カネカ 疎水性ペプチドの製造法
CN104327181A (zh) * 2014-09-28 2015-02-04 上海昂博生物技术有限公司 固相合成胸腺肽α1
CN108239147B (zh) * 2016-12-27 2023-11-10 江苏豪森药业集团有限公司 胸腺素α1衍生物的制备方法
CN111349152B (zh) * 2018-12-20 2022-04-05 深圳翰宇药业股份有限公司 一种制备胸腺法新的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68926178T2 (de) * 1988-05-10 1996-11-28 Alpha 1 Biomedicals Inc Festphase-Verfahren zur Gewinnung von Thymosin-alpha-1
US6262230B1 (en) * 1994-01-28 2001-07-17 Sciclone Pharmaceuticals Inc. Analogs of thymosin α1
US6204360B1 (en) * 1999-12-16 2001-03-20 Usa Universe Bioengineering, Inc. Retro-inverso thymosin alpha 1 hybrids
US7413738B2 (en) * 2002-08-13 2008-08-19 Enzon Pharmaceuticals, Inc. Releasable polymeric conjugates based on biodegradable linkers
CN100355786C (zh) * 2004-04-28 2007-12-19 江苏豪森药业股份有限公司 聚乙二醇修饰的胸腺肽1衍生物

Also Published As

Publication number Publication date
IL186774A0 (en) 2008-02-09
ATE440856T1 (de) 2009-09-15
MX2007013400A (es) 2008-04-29
ZA200708110B (en) 2008-10-29
US20090171068A1 (en) 2009-07-02
KR20080012884A (ko) 2008-02-12
ES2332666T3 (es) 2010-02-10
DE602006008781D1 (de) 2009-10-08
AU2006243344A1 (en) 2006-11-09
JP2008543733A (ja) 2008-12-04
EP1891104B1 (en) 2009-08-26
CA2600303A1 (en) 2006-11-09
DK1891104T3 (da) 2009-11-30
WO2006117227A3 (en) 2007-03-15
CN101166761A (zh) 2008-04-23
AU2006243344B2 (en) 2011-04-21
WO2006117227A2 (en) 2006-11-09
EP1891104A2 (en) 2008-02-27
PT1891104E (pt) 2009-12-07

Similar Documents

Publication Publication Date Title
NO20074623L (no) Fremgangsmate for peptidsyntese
CY1118343T1 (el) Αντισωματα συνδεσης twεακ
DK2292607T3 (da) Fremgangsmåde til syntese af organiske forbindelser
DK2030981T3 (da) Forbindelser til proteasom-enzymhæmning
DK1858491T3 (da) Sublingual overtrukket tablet
NO20071309L (no) Fremgangsmate for ekspansjon
DK1869019T3 (da) Bicycliske [3.1.0]heteroarylamider som glycintransportinhibitorer type I
DK2041158T3 (da) Peptid-epoxidketoner til proteasom inhibering
EP2141175A4 (en) PROCESS FOR SYNTHESIS OF A CYCLIC PEPTIDE COMPOUND
WO2007087416A3 (en) Methods of increasing oral bioavailability of tetracyclines
DK3421498T3 (da) Monoklonale antistoffer mod claudin-18 til behandling af cancer
DK2035451T3 (da) Insulinoptrop peptidsyntese
WO2007008684A3 (en) Ligands of melanocortin receptors
TW200617019A (en) A process for the preparation of 7α-alkylated 19-norsteroids
ME01459B (me) Postupak za doziranje medikamenata
EA200801414A1 (ru) Кальцилитические соединения
DK2019118T3 (da) Fremgangsmåde til syntetisering af thymosiner
IL197979A0 (en) Method for peptide synthesis
DK1866297T3 (da) Fremgangsmåde til fremstilling af en aminomethyl-thiazolforbindelse
ITMI20050477A1 (it) Cerotto transdermico
JP2007063161A5 (ja) 急性相反応タンパク質転写抑制剤
DK1700823T3 (da) Fremgangsmåde til fremstilling af syntesegas
DK1559681T3 (da) Fremgangsmåde til syntese af lamellære faststoffer under anvendelse af et organisk strukturmiddel af aminoalkoholtypen
ATE496061T1 (de) Festphasenpeptidsynthese
FR2864830B1 (fr) Procede de synthese sur support solide de composes peptidiques, notamment de composes peptidiques comportant un residu arginine

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application