NO20074414L - 1-H-pyrrol-2-karboksamider og imidazol-5-karboksamider og anvendelse derav for FAK, KDR og TIE2 kinasemodulatorer for behandling av kreft - Google Patents
1-H-pyrrol-2-karboksamider og imidazol-5-karboksamider og anvendelse derav for FAK, KDR og TIE2 kinasemodulatorer for behandling av kreftInfo
- Publication number
- NO20074414L NO20074414L NO20074414A NO20074414A NO20074414L NO 20074414 L NO20074414 L NO 20074414L NO 20074414 A NO20074414 A NO 20074414A NO 20074414 A NO20074414 A NO 20074414A NO 20074414 L NO20074414 L NO 20074414L
- Authority
- NO
- Norway
- Prior art keywords
- carboxamides
- cancer
- fak
- kdr
- pyrrole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Abstract
Oppfinnelsen vedrører substituerte imidazoler og pyrroler, sammensetninger som innholder samme, fremgangsmåte for fremstilling derav og anvendelse av samme. Mer spesielt vedrører oppfinnelsen fremstillingen av substituerte imidazoler og pyrroler, sammensetninger som innholder samme, fremgangsmåte for fremstilling derav og anvendelse av samme som et medikament, spesielt som anti-kreft midler.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0501092A FR2881426B1 (fr) | 2005-02-03 | 2005-02-03 | Pyrolles et imidazoles substitues, compositions les contenant, procede de frabrication et utilisation |
PCT/FR2006/000220 WO2006082309A1 (fr) | 2005-02-03 | 2006-02-01 | l-H-PYROLE-2-CARBOXAMIDES ET IMIDAZOLE-5-CARBOXAMIDES ET LEUR UTILISATION EN TANT MODULATEURS DES KINASES FAK, KDR ET TIE2 POUR TRAITER LE CANCER |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20074414L true NO20074414L (no) | 2007-11-05 |
Family
ID=34954950
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20074414A NO20074414L (no) | 2005-02-03 | 2007-08-29 | 1-H-pyrrol-2-karboksamider og imidazol-5-karboksamider og anvendelse derav for FAK, KDR og TIE2 kinasemodulatorer for behandling av kreft |
Country Status (20)
Country | Link |
---|---|
US (1) | US7560571B2 (no) |
EP (1) | EP1856043B1 (no) |
JP (1) | JP2008528661A (no) |
KR (1) | KR20070103420A (no) |
CN (1) | CN101133023A (no) |
AR (1) | AR053540A1 (no) |
AT (1) | ATE512133T1 (no) |
AU (1) | AU2006210343A1 (no) |
BR (1) | BRPI0606761A2 (no) |
CA (1) | CA2595987A1 (no) |
EA (1) | EA012267B1 (no) |
FR (1) | FR2881426B1 (no) |
IL (1) | IL184710A0 (no) |
MA (1) | MA29264B1 (no) |
MX (1) | MX2007009442A (no) |
NO (1) | NO20074414L (no) |
TW (1) | TW200640857A (no) |
UY (1) | UY29361A1 (no) |
WO (1) | WO2006082309A1 (no) |
ZA (1) | ZA200706338B (no) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2881742B1 (fr) | 2005-02-10 | 2007-09-07 | Aventis Pharma Sa | Pyrroles substitues, compositions les contenant, procede de fabrication et utilisation |
EP2007732B1 (en) | 2006-04-11 | 2011-11-23 | Vertex Pharmaceuticals, Inc. | Thiazoles, imidazoles, and pyrazoles useful as inhibitors of protein kinases |
AU2009262199B2 (en) | 2008-06-27 | 2012-08-09 | Amgen Inc. | Ang-2 inhibition to treat multiple sclerosis |
WO2010019909A1 (en) | 2008-08-15 | 2010-02-18 | N30 Pharmaceuticals, Llc | Pyrrole inhibitors of s-nitrosoglutathione reductase |
US8470857B2 (en) * | 2008-08-15 | 2013-06-25 | N30 Pharmaceuticals, Inc. | Pyrrole inhibitors of S-nitrosoglutathione reductase as therapeutic agents |
SI2315591T1 (sl) | 2008-08-15 | 2016-06-30 | Nivalis Therapeutics, Inc. | Novi pirolni inhibitorji S-nitrozoglutation reduktaze kot terapevtska sredstva |
CN102775354A (zh) * | 2011-05-10 | 2012-11-14 | 无锡立诺康医药科技有限公司 | 一种合成4-芳基-5-羧酸咪唑及其酯的工艺方法 |
AU2013299557B2 (en) | 2012-08-10 | 2017-06-22 | Boehringer Ingelheim International Gmbh | Heteroaromatic compounds as Bruton's tyrosine kinase (BTK) inhibitors |
US9828364B2 (en) | 2014-01-29 | 2017-11-28 | Boehringer Ingelheim International Gmbh | Pyrazole compounds as BTK inhibitors |
HUE056877T2 (hu) | 2015-12-16 | 2022-03-28 | Boehringer Ingelheim Int | Autoimmun betegségek kezelésére alkalmas bipirazolil-származékok |
JP6916185B2 (ja) | 2016-01-13 | 2021-08-11 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Btk阻害剤としてのイソキノロン類 |
WO2020113094A1 (en) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020173507A1 (en) * | 2000-08-15 | 2002-11-21 | Vincent Santora | Urea compounds and methods of uses |
GB0107901D0 (en) * | 2001-03-29 | 2001-05-23 | Cyclacel Ltd | Anti-cancer compounds |
AU2002366440A1 (en) * | 2001-09-27 | 2003-09-09 | Smithkline Beecham Corporation | Chemical compounds |
US20040138269A1 (en) * | 2002-10-11 | 2004-07-15 | Sugen, Inc. | Substituted pyrroles as kinase inhibitors |
CA2521962A1 (en) * | 2003-04-30 | 2004-11-11 | Pfizer Products Inc. | Anti-diabetic agents |
DE10354060A1 (de) * | 2003-11-19 | 2005-06-02 | Merck Patent Gmbh | Pyrrolderivate |
US7183285B2 (en) | 2004-04-29 | 2007-02-27 | Pharmix Corp. | Compositions and treatments for inhibiting kinase and/or HMG-CoA reductase |
FR2881742B1 (fr) | 2005-02-10 | 2007-09-07 | Aventis Pharma Sa | Pyrroles substitues, compositions les contenant, procede de fabrication et utilisation |
-
2005
- 2005-02-03 FR FR0501092A patent/FR2881426B1/fr not_active Expired - Fee Related
-
2006
- 2006-01-26 TW TW095102965A patent/TW200640857A/zh unknown
- 2006-02-01 JP JP2007553647A patent/JP2008528661A/ja active Pending
- 2006-02-01 AR ARP060100362A patent/AR053540A1/es unknown
- 2006-02-01 AT AT06709213T patent/ATE512133T1/de not_active IP Right Cessation
- 2006-02-01 AU AU2006210343A patent/AU2006210343A1/en not_active Withdrawn
- 2006-02-01 EP EP06709213A patent/EP1856043B1/fr active Active
- 2006-02-01 CA CA002595987A patent/CA2595987A1/fr not_active Abandoned
- 2006-02-01 MX MX2007009442A patent/MX2007009442A/es not_active Application Discontinuation
- 2006-02-01 CN CNA2006800069922A patent/CN101133023A/zh active Pending
- 2006-02-01 WO PCT/FR2006/000220 patent/WO2006082309A1/fr active Application Filing
- 2006-02-01 KR KR1020077017902A patent/KR20070103420A/ko not_active Application Discontinuation
- 2006-02-01 BR BRPI0606761-1A patent/BRPI0606761A2/pt not_active IP Right Cessation
- 2006-02-01 ZA ZA200706338A patent/ZA200706338B/xx unknown
- 2006-02-01 EA EA200701648A patent/EA012267B1/ru not_active IP Right Cessation
- 2006-02-03 UY UY29361A patent/UY29361A1/es unknown
-
2007
- 2007-07-18 IL IL184710A patent/IL184710A0/en unknown
- 2007-08-01 US US11/832,206 patent/US7560571B2/en not_active Expired - Fee Related
- 2007-08-23 MA MA30160A patent/MA29264B1/fr unknown
- 2007-08-29 NO NO20074414A patent/NO20074414L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
FR2881426B1 (fr) | 2007-03-30 |
ATE512133T1 (de) | 2011-06-15 |
TW200640857A (en) | 2006-12-01 |
JP2008528661A (ja) | 2008-07-31 |
EP1856043A1 (fr) | 2007-11-21 |
FR2881426A1 (fr) | 2006-08-04 |
AR053540A1 (es) | 2007-05-09 |
UY29361A1 (es) | 2006-08-31 |
WO2006082309A1 (fr) | 2006-08-10 |
BRPI0606761A2 (pt) | 2009-07-14 |
KR20070103420A (ko) | 2007-10-23 |
US20080045542A1 (en) | 2008-02-21 |
EA012267B1 (ru) | 2009-08-28 |
EA200701648A1 (ru) | 2008-02-28 |
MA29264B1 (fr) | 2008-02-01 |
AU2006210343A1 (en) | 2006-08-10 |
ZA200706338B (en) | 2008-11-26 |
CA2595987A1 (fr) | 2006-08-10 |
MX2007009442A (es) | 2008-03-10 |
EP1856043B1 (fr) | 2011-06-08 |
IL184710A0 (en) | 2007-12-03 |
US7560571B2 (en) | 2009-07-14 |
CN101133023A (zh) | 2008-02-27 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |