NO20073440L - Prosess for fremstilling av candesartan - Google Patents

Prosess for fremstilling av candesartan

Info

Publication number
NO20073440L
NO20073440L NO20073440A NO20073440A NO20073440L NO 20073440 L NO20073440 L NO 20073440L NO 20073440 A NO20073440 A NO 20073440A NO 20073440 A NO20073440 A NO 20073440A NO 20073440 L NO20073440 L NO 20073440L
Authority
NO
Norway
Prior art keywords
candesartan
making
preparation
processes
novel
Prior art date
Application number
NO20073440A
Other languages
English (en)
Norwegian (no)
Inventor
Yaping Wang
Yonggang Li
Yulin Li
Guojun Zheng
Yi Li
Stefan Kocher
Original Assignee
Ratiopharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ratiopharm Gmbh filed Critical Ratiopharm Gmbh
Publication of NO20073440L publication Critical patent/NO20073440L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04—Formation of amino groups in compounds containing carboxyl groups
    • C07C227/10—Formation of amino groups in compounds containing carboxyl groups with simultaneously increasing the number of carbon atoms in the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C229/56—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in ortho-position
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C229/60—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in meta- or para- positions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
NO20073440A 2004-12-16 2007-07-03 Prosess for fremstilling av candesartan NO20073440L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004060699A DE102004060699A1 (de) 2004-12-16 2004-12-16 Verfahren zur Herstellung von Candesartan
PCT/DE2005/002267 WO2006063578A2 (de) 2004-12-16 2005-12-15 Verfahren zur herstellung von candesartan

Publications (1)

Publication Number Publication Date
NO20073440L true NO20073440L (no) 2007-07-03

Family

ID=36168493

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20073440A NO20073440L (no) 2004-12-16 2007-07-03 Prosess for fremstilling av candesartan

Country Status (12)

Country Link
US (1) US20080114045A1 (zh)
EP (1) EP1838699B1 (zh)
CN (1) CN101068807A (zh)
AT (1) ATE466010T1 (zh)
CA (1) CA2587501A1 (zh)
DE (2) DE102004060699A1 (zh)
ES (1) ES2344571T3 (zh)
IL (1) IL183104A0 (zh)
NO (1) NO20073440L (zh)
PT (1) PT1838699E (zh)
RU (1) RU2407741C2 (zh)
WO (1) WO2006063578A2 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2264641B1 (es) * 2005-06-17 2008-03-01 Quimica Sintetica, S.A. Procedimiento para la obtencion de derivados de bencimidazol y sus intermedios.
CN101323610B (zh) * 2007-06-15 2013-10-30 横店集团成都分子实验室有限公司 三苯甲基坎地沙坦酯中间体制备方法
CN101633656B (zh) * 2009-09-08 2013-06-26 江苏德峰药业有限公司 沙坦类药物坎地沙坦的合成方法
CN101781286B (zh) * 2010-01-28 2013-07-10 青岛黄海制药有限责任公司 一种制备坎地沙坦酯的方法
CN101880241B (zh) * 2010-07-14 2013-04-17 浙江美诺华药物化学有限公司 一锅法制备2-(取代苯基)甲氨基-3-硝基苯甲酸甲酯的方法
ES2960987T3 (es) 2019-04-12 2024-03-07 Riboscience Llc Derivados de heteroarilo bicíclicos como inhibidores de la ectonucleótido pirofosfatasa fosfodiesterasa 1

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4820843A (en) * 1987-05-22 1989-04-11 E. I. Du Pont De Nemours And Company Tetrazole intermediates to antihypertensive compounds
US4880804A (en) * 1988-01-07 1989-11-14 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking benzimidazoles
IL95975A (en) * 1989-10-24 1997-06-10 Takeda Chemical Industries Ltd N-benzyl- 2-alkylbenzimidazole derivatives, their production and pharmaceutical compositions containing them
US5196444A (en) * 1990-04-27 1993-03-23 Takeda Chemical Industries, Ltd. 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof
DE69233734D1 (de) * 1991-11-18 2008-06-26 Du Pont 2-(2'-Triphenylmethyl-2'H-tetrazol-5'-yl)phenylborsäure als Zwischenprodukt zur Synthese von A II Receptorenantagonisten
ATE240325T1 (de) * 1995-06-07 2003-05-15 Wyeth Corp Verfahren zur herstellung von biphenylderivaten
US6177587B1 (en) * 1997-05-26 2001-01-23 Takeda Chemical Industries, Ltd. Production method of aminobenzene compound
US6590100B2 (en) * 2000-03-08 2003-07-08 Rhodia Chimie Process for preparing a polyaromatic compound
CN1207287C (zh) * 2002-12-23 2005-06-22 重庆圣华曦药业有限公司 苯并咪唑的酯类化合物及其制备方法和在制备药用化合物坎地沙坦酯中的应用
ES2281312T3 (es) * 2003-01-16 2008-08-01 Teva Pharmaceutical Industries Ltd. Nueva sintesis de irbesartan.
US7504516B2 (en) * 2003-03-27 2009-03-17 Hetero Drugs Limited Crystalline forms of candesartan cilexetil
ITMI20032338A1 (it) * 2003-11-28 2005-05-29 Dinamite Dipharma S P A In Forma A Bbreviata Diph Composti feniltetrazolici.

Also Published As

Publication number Publication date
ES2344571T3 (es) 2010-08-31
EP1838699B1 (de) 2010-04-28
DE102004060699A1 (de) 2006-06-22
WO2006063578A3 (de) 2006-10-12
CA2587501A1 (en) 2006-06-22
RU2407741C2 (ru) 2010-12-27
IL183104A0 (en) 2007-09-20
US20080114045A1 (en) 2008-05-15
ATE466010T1 (de) 2010-05-15
RU2007125799A (ru) 2009-01-27
DE502005009501D1 (de) 2010-06-10
WO2006063578A2 (de) 2006-06-22
PT1838699E (pt) 2010-07-07
CN101068807A (zh) 2007-11-07
EP1838699A2 (de) 2007-10-03

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Legal Events

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