NO20072879L - Metoder og forbindelser for fremstilling av substituterte naftylindolderivater - Google Patents
Metoder og forbindelser for fremstilling av substituterte naftylindolderivaterInfo
- Publication number
- NO20072879L NO20072879L NO20072879A NO20072879A NO20072879L NO 20072879 L NO20072879 L NO 20072879L NO 20072879 A NO20072879 A NO 20072879A NO 20072879 A NO20072879 A NO 20072879A NO 20072879 L NO20072879 L NO 20072879L
- Authority
- NO
- Norway
- Prior art keywords
- substituted
- preparation
- compounds
- methods
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Foreliggende oppfinnelse tilveiebringer prosesser for fremstilling av substituerte naftylindol derivater som kan anvendes som inhibitorer av plasminogen aktivator inhibitor-1 (PAI-1). I visse utførelsesformer ifølge oppfinnelsen, involverer prosessene reaksjoner som omfatter én eller flere av en Oppenauer oksidasjon, en Fischer indol syntese, en metyleter spaltning eller kobling av et substituert metyltetrazol med et substituert naftol. ?? ?? ?? ?? 40
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64761805P | 2005-01-27 | 2005-01-27 | |
PCT/US2006/002996 WO2006081455A1 (en) | 2005-01-27 | 2006-01-25 | Processes and compounds for the preparation of substituted naphthylindole derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20072879L true NO20072879L (no) | 2007-06-26 |
Family
ID=36570379
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20072879A NO20072879L (no) | 2005-01-27 | 2007-06-06 | Metoder og forbindelser for fremstilling av substituterte naftylindolderivater |
Country Status (21)
Country | Link |
---|---|
US (2) | US7323483B2 (no) |
EP (1) | EP1856104A1 (no) |
JP (1) | JP2008528618A (no) |
KR (1) | KR20070103744A (no) |
CN (1) | CN101111491A (no) |
AR (1) | AR053437A1 (no) |
AU (1) | AU2006208021A1 (no) |
BR (1) | BRPI0606871A2 (no) |
CA (1) | CA2595376A1 (no) |
CR (1) | CR9215A (no) |
GT (1) | GT200600032A (no) |
HN (1) | HN2006003347A (no) |
IL (1) | IL183712A0 (no) |
MX (1) | MX2007008952A (no) |
NI (1) | NI200700188A (no) |
NO (1) | NO20072879L (no) |
PE (1) | PE20061200A1 (no) |
RU (1) | RU2007121255A (no) |
TW (1) | TW200637850A (no) |
WO (1) | WO2006081455A1 (no) |
ZA (1) | ZA200706203B (no) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2007092207A1 (en) * | 2006-02-03 | 2007-08-16 | Wyeth | Compositions for the delivery of substituted naphthyl indole derivatives and methods of their use |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE903206A1 (en) | 1989-09-07 | 1991-03-13 | Abbott Lab | Indole-, benzofuran-, and benzothiophene-containing¹lipoxygenase-inhibiting compounds |
US5151435A (en) | 1991-04-08 | 1992-09-29 | Merck & Co., Inc. | Angiotensin ii antagonists incorporating an indole or dihydroindole |
IL101785A0 (en) | 1991-05-10 | 1992-12-30 | Fujisawa Pharmaceutical Co | Urea derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
IL109568A0 (en) | 1993-05-19 | 1994-08-26 | Fujisawa Pharmaceutical Co | Urea derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof |
US6756388B1 (en) | 1993-10-12 | 2004-06-29 | Pfizer Inc. | Benzothiophenes and related compounds as estrogen agonists |
CA2134192A1 (en) | 1993-11-12 | 1995-05-13 | Michael L. Denney | 5, 6-bicyclic glycoprotein iib/iiia antagonists |
US5552412A (en) | 1995-01-09 | 1996-09-03 | Pfizer Inc | 5-substitued-6-cyclic-5,6,7,8-tetrahydronaphthalen2-ol compounds which are useful for treating osteoporosis |
TR199700334T1 (tr) | 1995-09-01 | 1997-08-21 | Lilly Co Eli | Indolil nöropeptid y reseptör antagonistleri. |
CA2264020A1 (en) | 1996-08-26 | 1998-03-05 | Jean Bemis | Inhibitors of phospholipase enzymes |
US6703527B2 (en) | 2001-05-24 | 2004-03-09 | Nikken Chemicals Co., Ltd. | Method for oxidation of allyl alcohol |
TWI224101B (en) * | 2001-06-20 | 2004-11-21 | Wyeth Corp | Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1) |
TW591020B (en) | 2001-06-20 | 2004-06-11 | Wyeth Corp | 6-(aryl-amido or aryl-amidomethyl)-naphthalen-2-yloxy-acidic derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1) |
-
2006
- 2006-01-25 AU AU2006208021A patent/AU2006208021A1/en not_active Abandoned
- 2006-01-25 CN CNA2006800033140A patent/CN101111491A/zh active Pending
- 2006-01-25 MX MX2007008952A patent/MX2007008952A/es active IP Right Grant
- 2006-01-25 EP EP06719721A patent/EP1856104A1/en not_active Withdrawn
- 2006-01-25 BR BRPI0606871-5A patent/BRPI0606871A2/pt not_active IP Right Cessation
- 2006-01-25 KR KR1020077017498A patent/KR20070103744A/ko not_active Application Discontinuation
- 2006-01-25 RU RU2007121255/04A patent/RU2007121255A/ru not_active Application Discontinuation
- 2006-01-25 CA CA002595376A patent/CA2595376A1/en not_active Abandoned
- 2006-01-25 JP JP2007553280A patent/JP2008528618A/ja not_active Withdrawn
- 2006-01-25 US US11/339,802 patent/US7323483B2/en not_active Expired - Fee Related
- 2006-01-25 WO PCT/US2006/002996 patent/WO2006081455A1/en active Application Filing
- 2006-01-26 PE PE2006000111A patent/PE20061200A1/es not_active Application Discontinuation
- 2006-01-26 TW TW095102979A patent/TW200637850A/zh unknown
- 2006-01-26 GT GT200600032A patent/GT200600032A/es unknown
- 2006-01-26 AR ARP060100283A patent/AR053437A1/es unknown
- 2006-01-30 HN HN2006003347A patent/HN2006003347A/es unknown
-
2007
- 2007-06-06 IL IL183712A patent/IL183712A0/en unknown
- 2007-06-06 NO NO20072879A patent/NO20072879L/no not_active Application Discontinuation
- 2007-06-28 CR CR9215A patent/CR9215A/es not_active Application Discontinuation
- 2007-07-26 ZA ZA200706203A patent/ZA200706203B/xx unknown
- 2007-07-27 NI NI200700188A patent/NI200700188A/es unknown
- 2007-11-28 US US11/946,109 patent/US20080071091A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
GT200600032A (es) | 2006-11-14 |
CN101111491A (zh) | 2008-01-23 |
TW200637850A (en) | 2006-11-01 |
HN2006003347A (es) | 2011-03-30 |
MX2007008952A (es) | 2007-09-18 |
CR9215A (es) | 2007-11-23 |
WO2006081455A1 (en) | 2006-08-03 |
BRPI0606871A2 (pt) | 2009-07-21 |
AU2006208021A1 (en) | 2006-08-03 |
ZA200706203B (en) | 2009-12-30 |
CA2595376A1 (en) | 2006-08-03 |
EP1856104A1 (en) | 2007-11-21 |
US20060183917A1 (en) | 2006-08-17 |
US20080071091A1 (en) | 2008-03-20 |
NI200700188A (es) | 2008-05-09 |
IL183712A0 (en) | 2007-09-20 |
RU2007121255A (ru) | 2009-03-10 |
JP2008528618A (ja) | 2008-07-31 |
PE20061200A1 (es) | 2006-12-19 |
AR053437A1 (es) | 2007-05-09 |
KR20070103744A (ko) | 2007-10-24 |
US7323483B2 (en) | 2008-01-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |