NO20072461L - Fremstilling og anvendelse av bifenyl-4-yl-karbonylaminosyre derivater for behandling av fedme - Google Patents
Fremstilling og anvendelse av bifenyl-4-yl-karbonylaminosyre derivater for behandling av fedmeInfo
- Publication number
- NO20072461L NO20072461L NO20072461A NO20072461A NO20072461L NO 20072461 L NO20072461 L NO 20072461L NO 20072461 A NO20072461 A NO 20072461A NO 20072461 A NO20072461 A NO 20072461A NO 20072461 L NO20072461 L NO 20072461L
- Authority
- NO
- Norway
- Prior art keywords
- biphenyl
- obesity
- preparation
- treatment
- acid derivatives
- Prior art date
Links
- 208000008589 Obesity Diseases 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title abstract 2
- -1 biphenyl-4-yl-carbonylamino Chemical group 0.000 title abstract 2
- 235000020824 obesity Nutrition 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61897504P | 2004-10-15 | 2004-10-15 | |
| PCT/US2005/037215 WO2006044775A2 (en) | 2004-10-15 | 2005-10-14 | Preparation and use of biphenyl-4-yl-carbonylamino acid derivatives for the treatment of obesity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20072461L true NO20072461L (no) | 2007-07-03 |
Family
ID=36203612
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20072461A NO20072461L (no) | 2004-10-15 | 2007-05-14 | Fremstilling og anvendelse av bifenyl-4-yl-karbonylaminosyre derivater for behandling av fedme |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US7759376B2 (es) |
| EP (1) | EP1805156B1 (es) |
| JP (1) | JP2008516978A (es) |
| KR (1) | KR20070063546A (es) |
| CN (1) | CN101087769A (es) |
| AT (1) | ATE492542T1 (es) |
| AU (1) | AU2005295453A1 (es) |
| BR (1) | BRPI0516483A (es) |
| CA (1) | CA2583784A1 (es) |
| CR (1) | CR9034A (es) |
| DE (1) | DE602005025517D1 (es) |
| EA (1) | EA200700851A1 (es) |
| EC (1) | ECSP077397A (es) |
| ES (1) | ES2357015T3 (es) |
| IL (1) | IL182218A0 (es) |
| MA (1) | MA28935B1 (es) |
| MX (1) | MX2007004217A (es) |
| NO (1) | NO20072461L (es) |
| TN (1) | TNSN07111A1 (es) |
| WO (1) | WO2006044775A2 (es) |
| ZA (1) | ZA200703002B (es) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ555683A (en) | 2004-12-14 | 2010-09-30 | Astrazeneca Ab | Oxadiazole derivatives as dgat inhibitors |
| JP5117391B2 (ja) | 2005-11-21 | 2013-01-16 | アナディス ファーマシューティカルズ インク | ５−アミノ−３Ｈ−チアゾロ［４，５−ｄ］ピリミジン−２−オンを調製するための新規な方法 |
| AR058562A1 (es) | 2005-12-22 | 2008-02-13 | Astrazeneca Ab | Derivados de pirimido [4,5 b] (1,4) oxazinas , procedimientos de obtencion y su uso como inhibidores de acetil coa y dgat 1 |
| PL2402319T3 (pl) | 2006-03-31 | 2018-02-28 | Novartis Ag | Inhibitory DGAT |
| ES2356097T3 (es) | 2006-05-30 | 2011-04-04 | Astrazeneca Ab | Ácidos 5-fenilamino-1,3,4-oxadiazol-2-ilcarbonilamino-4-fenoxi-ciclohexancarboxílico sustituidos como inhibidores de la acetil coenzima a diacilglicerol aciltransferasa. |
| WO2007138304A1 (en) | 2006-05-30 | 2007-12-06 | Astrazeneca Ab | 1, 3, 4 -oxadiazole derivatives as dgat1 inhibitors |
| KR100811100B1 (ko) | 2006-09-27 | 2008-03-06 | 한국생명공학연구원 | 벤즈아졸 유도체를 유효성분으로 함유하는 대사성 질환예방 및 치료용 약학적 조성물 |
| KR100795462B1 (ko) | 2006-09-27 | 2008-01-16 | 한국생명공학연구원 | 인돌 유도체, 이의 제조방법 및 이를 유효성분으로함유하는 대사성 질환 예방 및 치료용 약학적 조성물 |
| PE20080888A1 (es) * | 2006-10-18 | 2008-08-26 | Novartis Ag | COMPUESTOS HETEROCICLICOS COMO INHIBIDORES DE LA ACIL-TRANSFERASA DE ACIL-CoA-DIACIL-GLICEROL 1 (DGAT1) |
| CA2671315A1 (en) * | 2006-12-11 | 2008-06-19 | Novartis Ag | Method of preventing or treating myocardial ischemia by inhibiting dgat1 enzyme with a dgat1 inhibitor |
| CA2687754C (en) | 2007-06-08 | 2015-12-08 | Janssen Pharmaceutica N.V. | Piperidine, piperazine derivatives for use as dgat inhibitors |
| US8633197B2 (en) | 2007-06-08 | 2014-01-21 | Janssen Pharmaceutica N.V. | Piperidine/piperazine derivatives |
| JO2972B1 (en) | 2007-06-08 | 2016-03-15 | جانسين فارماسوتيكا ان. في | Piperidine / piperazine derivatives |
| CA2687912C (en) | 2007-06-08 | 2015-11-03 | Janssen Pharmaceutica N.V. | Piperidine/piperazine derivatives |
| AR066169A1 (es) | 2007-09-28 | 2009-07-29 | Novartis Ag | Derivados de benzo-imidazoles, utiles para trastornos asociados con la actividad de dgat |
| ES2535083T3 (es) | 2007-12-20 | 2015-05-05 | Astrazeneca Ab | Compuestos de carbamoilo como inhibidores 190 de DGAT1 |
| NZ588807A (en) | 2008-05-05 | 2011-07-29 | Sanofi Aventis | Acylamino-substituted fused cyclopentanecarboxylic acid derivatives and their use as pharmaceuticals |
| UY31863A (es) | 2008-06-05 | 2010-01-05 | Janssen Pharmaceutica Nv | Combinaciones de drogas que comprenden un inhibidor de dgat y un agonista de ppar |
| UY32349A (es) * | 2008-12-23 | 2010-07-30 | Novartis Ag | Derivados de biaril-bencil-amina |
| CA2749700A1 (en) * | 2009-01-23 | 2010-07-29 | Msd K.K. | Benzodiazepin-2-on derivatives |
| EP2805951B1 (en) | 2009-03-20 | 2018-03-14 | Metabasis Therapeutics, Inc. | Inhibitors of diacylglycerol o-acyltransferase 1 (DGAT-1) and uses thereof |
| US8268820B2 (en) * | 2009-03-26 | 2012-09-18 | Hoffmann-La Roche Inc. | 2,3-diaryl- or heteroaryl-substituted 1,1,1-trifluoro-2-hydroxypropyl compounds |
| AU2010229653A1 (en) | 2009-03-27 | 2011-10-20 | Astrazeneca Ab | Methods for preventing major adverse cardiovascular events with DPP-IV inhibitors |
| WO2010146395A1 (en) | 2009-06-19 | 2010-12-23 | Astrazeneca Ab | Pyrazine carboxamides as inhibitors of dgat1 |
| AR079022A1 (es) * | 2009-11-02 | 2011-12-21 | Sanofi Aventis | Derivados de acido carboxilico ciclico sustituidos con acilamino, su uso como productos farmaceuticos, composicion farmaceutica y metodo de preparacion |
| NZ599855A (en) | 2009-11-05 | 2014-06-27 | Piramal Entpr Ltd | Carboxy oxazole or thiazole compounds as dgat - 1 inhibitors useful for the treatment of obesity |
| UA111709C2 (uk) * | 2009-12-16 | 2016-06-10 | Пола Кемікал Індастріз Інк. | Застосування похідних n-бензоїлсерину для запобігання або ослаблення пігментації |
| BR112012024618A2 (pt) | 2010-03-30 | 2019-09-24 | Novartis Ag | usos de inibidores de dgat1 |
| WO2012150784A2 (ko) | 2011-05-03 | 2012-11-08 | 한국생명공학연구원 | 신규한 인돌 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 대사성 질환의 예방 또는 치료용 약학적 조성물 |
| WO2013055910A1 (en) | 2011-10-12 | 2013-04-18 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| EP2892896B1 (en) | 2012-09-05 | 2016-06-29 | Bristol-Myers Squibb Company | Pyrrolone or pyrrolidinone melanin concentrating hormore receptor-1 antagonists |
| EP2892897A1 (en) | 2012-09-05 | 2015-07-15 | Bristol-Myers Squibb Company | Pyrrolone or pyrrolidinone melanin concentrating hormone receptor-1 antagonists |
| WO2014074668A1 (en) | 2012-11-08 | 2014-05-15 | Arena Pharmaceuticals, Inc. | Modulators of gpr119 and the treatment of disorders related thereto |
| EP3174875B1 (de) * | 2014-08-01 | 2020-08-19 | Bayer Pharma Aktiengesellschaft | Verfahren zur herstellung von (4s)- 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridin-3-carbox-amid und dessen aufreinigung für die verwendung als pharmazeutischer wirkstoff |
| CN105646510A (zh) * | 2014-12-02 | 2016-06-08 | 重庆宁牧生态农业有限公司 | 一种用作抗肥胖剂的化合物 |
| EP3765012A4 (en) | 2018-03-16 | 2021-12-15 | Anji Pharmaceuticals Inc. | COMPOSITIONS AND METHODS OF TREATMENT OF SERIOUS CONSTIPATION |
| WO2020252353A1 (en) * | 2019-06-12 | 2020-12-17 | Vanderbilt University | Amino acid transport inhibitors and the uses thereof |
| CN112336718A (zh) * | 2020-10-19 | 2021-02-09 | 济南大学 | 一种苯并咪唑衍生物作为α-葡萄糖苷酶抑制剂及其应用 |
| WO2023085931A1 (en) | 2021-11-11 | 2023-05-19 | Koninklijke Nederlandse Akademie Van Wetenschappen | Hepatic organoids |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4164645B2 (ja) * | 2002-08-09 | 2008-10-15 | 株式会社大塚製薬工場 | Ｄｇａｔ阻害剤 |
| CN1753897A (zh) * | 2002-11-22 | 2006-03-29 | 日本烟草产业株式会社 | 稠合双环含氮杂环 |
| AR044152A1 (es) * | 2003-05-09 | 2005-08-24 | Bayer Corp | Derivados de alquilarilo, metodo de preparacion y uso para el tratamiento de la obesidad |
-
2005
- 2005-10-14 BR BRPI0516483-4A patent/BRPI0516483A/pt not_active IP Right Cessation
- 2005-10-14 US US11/665,317 patent/US7759376B2/en not_active Expired - Fee Related
- 2005-10-14 WO PCT/US2005/037215 patent/WO2006044775A2/en active Application Filing
- 2005-10-14 EA EA200700851A patent/EA200700851A1/ru unknown
- 2005-10-14 AT AT05812611T patent/ATE492542T1/de not_active IP Right Cessation
- 2005-10-14 JP JP2007536988A patent/JP2008516978A/ja active Pending
- 2005-10-14 DE DE602005025517T patent/DE602005025517D1/de active Active
- 2005-10-14 ES ES05812611T patent/ES2357015T3/es active Active
- 2005-10-14 MX MX2007004217A patent/MX2007004217A/es not_active Application Discontinuation
- 2005-10-14 CA CA002583784A patent/CA2583784A1/en not_active Abandoned
- 2005-10-14 CN CNA2005800433280A patent/CN101087769A/zh active Pending
- 2005-10-14 KR KR1020077008522A patent/KR20070063546A/ko not_active Application Discontinuation
- 2005-10-14 AU AU2005295453A patent/AU2005295453A1/en not_active Abandoned
- 2005-10-14 EP EP05812611A patent/EP1805156B1/en not_active Not-in-force
-
2007
- 2007-03-27 IL IL182218A patent/IL182218A0/en unknown
- 2007-03-28 TN TNP2007000111A patent/TNSN07111A1/en unknown
- 2007-03-30 CR CR9034A patent/CR9034A/es not_active Application Discontinuation
- 2007-04-12 ZA ZA200703002A patent/ZA200703002B/xx unknown
- 2007-04-13 EC EC2007007397A patent/ECSP077397A/es unknown
- 2007-04-17 MA MA29831A patent/MA28935B1/fr unknown
- 2007-05-14 NO NO20072461A patent/NO20072461L/no not_active Application Discontinuation
-
2010
- 2010-07-14 US US12/836,035 patent/US20110118302A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ECSP077397A (es) | 2007-05-30 |
| EA200700851A1 (ru) | 2007-12-28 |
| KR20070063546A (ko) | 2007-06-19 |
| EP1805156B1 (en) | 2010-12-22 |
| JP2008516978A (ja) | 2008-05-22 |
| EP1805156A4 (en) | 2009-06-10 |
| EP1805156A2 (en) | 2007-07-11 |
| MA28935B1 (fr) | 2007-10-01 |
| WO2006044775A2 (en) | 2006-04-27 |
| WO2006044775A3 (en) | 2006-06-15 |
| IL182218A0 (en) | 2007-09-20 |
| US7759376B2 (en) | 2010-07-20 |
| CR9034A (es) | 2008-11-18 |
| AU2005295453A1 (en) | 2006-04-27 |
| DE602005025517D1 (de) | 2011-02-03 |
| CA2583784A1 (en) | 2006-04-27 |
| BRPI0516483A (pt) | 2008-09-02 |
| ES2357015T3 (es) | 2011-04-15 |
| US20110118302A1 (en) | 2011-05-19 |
| MX2007004217A (es) | 2007-06-11 |
| CN101087769A (zh) | 2007-12-12 |
| TNSN07111A1 (en) | 2008-06-02 |
| ZA200703002B (en) | 2008-08-27 |
| ATE492542T1 (de) | 2011-01-15 |
| US20070265298A1 (en) | 2007-11-15 |
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