NO20072457L - Plasmider som koder for p185neu proteinsekvensvarianter og terapeutisk anvendelse derav - Google Patents

Plasmider som koder for p185neu proteinsekvensvarianter og terapeutisk anvendelse derav

Info

Publication number
NO20072457L
NO20072457L NO20072457A NO20072457A NO20072457L NO 20072457 L NO20072457 L NO 20072457L NO 20072457 A NO20072457 A NO 20072457A NO 20072457 A NO20072457 A NO 20072457A NO 20072457 L NO20072457 L NO 20072457L
Authority
NO
Norway
Prior art keywords
protein sequence
therapeutic use
sequence variants
plasmids encoding
p185neu
Prior art date
Application number
NO20072457A
Other languages
English (en)
Other versions
NO344353B1 (no
Inventor
Augusto Amici
Cristina Marchini
Elena Quaglino
Federica Cavallo
Guido Forni
Original Assignee
Guido Forni
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guido Forni filed Critical Guido Forni
Publication of NO20072457L publication Critical patent/NO20072457L/no
Publication of NO344353B1 publication Critical patent/NO344353B1/no

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/64General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001102Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103Receptors for growth factors
    • A61K39/001106Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ErbB4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

DNA-plasmider inneholdende sekvenskoder for forskjellige fragmenter av 185neu-onkoprotein som er i stand til å indusere en immunreaksjon mot p185neu-overuttrykkende tumorer, og farmasøytiske sammensetninger derav er beskrevet.
NO20072457A 2004-10-15 2007-05-14 Plasmider som koder for p185neu proteinsekvensvarianter og terapeutisk anvendelse derav NO344353B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001965A ITMI20041965A1 (it) 2004-10-15 2004-10-15 "dna codificante forme tronche e chimeriche della proteina p185neu e suoi usi terapeutici"
PCT/IB2005/003052 WO2006040660A2 (en) 2004-10-15 2005-10-13 Plasmids coding for p185neu protein sequence variants and therapeutic uses thereof

Publications (2)

Publication Number Publication Date
NO20072457L true NO20072457L (no) 2007-07-13
NO344353B1 NO344353B1 (no) 2019-11-11

Family

ID=35539028

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20072457A NO344353B1 (no) 2004-10-15 2007-05-14 Plasmider som koder for p185neu proteinsekvensvarianter og terapeutisk anvendelse derav

Country Status (22)

Country Link
US (2) US7985582B2 (no)
EP (2) EP1809668A2 (no)
JP (1) JP5597346B2 (no)
KR (1) KR101337706B1 (no)
CN (2) CN101886090B (no)
AT (1) ATE524494T1 (no)
AU (1) AU2005293218B2 (no)
CA (1) CA2583499C (no)
DK (1) DK1939217T3 (no)
ES (1) ES2370540T3 (no)
HK (1) HK1150627A1 (no)
HR (1) HRP20110729T1 (no)
IL (1) IL182510A0 (no)
IT (1) ITMI20041965A1 (no)
NO (1) NO344353B1 (no)
PL (1) PL1939217T3 (no)
PT (1) PT1939217E (no)
RU (1) RU2383620C2 (no)
SG (1) SG148195A1 (no)
SI (1) SI1939217T1 (no)
WO (1) WO2006040660A2 (no)
ZA (1) ZA200703875B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101638440B (zh) * 2008-07-29 2011-10-26 中国人民解放军军事医学科学院基础医学研究所 一种可诱发机体抗肿瘤免疫的异种抗原-Fc融合蛋白及其应用
EP2777711A1 (en) 2013-03-11 2014-09-17 Icon Genetics GmbH Her2/Neu cancer vaccine
US11667960B2 (en) * 2016-04-20 2023-06-06 Arizona Board Of Regents On Behalf Of The University Of Arizona Methods and systems for RNA or DNA detection and sequencing

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5518885A (en) * 1994-04-19 1996-05-21 The United States Of America As Represented By The Department Of Health & Human Services ERBB2 promoter binding protein in neoplastic disease
US7820180B2 (en) * 2004-09-24 2010-10-26 The Trustees Of The University Of Pennsylvania Listeria-based and LLO-based vaccines
US7794729B2 (en) * 1994-11-08 2010-09-14 The Trustees Of The University Of Pennsylvania Methods and compositions for immunotherapy of cancer
CZ20012587A3 (cs) * 1999-01-29 2002-05-15 Corixa Corporation Izolovaný protein, nukleová kyselina, virový vektor, farmaceutický prostředek, izolovaná populace T buněk, způsob posílení imunitní odpovědi, způsob odstranění nádorových buněk, způsob stimulace a/nebo namnoľení T buněk a způsob přípravy fúzního proteinu
US20020177551A1 (en) 2000-05-31 2002-11-28 Terman David S. Compositions and methods for treatment of neoplastic disease
AU2003286770A1 (en) * 2002-10-30 2004-06-07 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services METHODS FOR PROPHYLAXIS AND TREATMENT OF HER-2/neu TUMORS
DE10251520A1 (de) * 2002-11-04 2004-05-13 Valeo Wischersysteme Gmbh Adapter für ein Wischblatt
AU2003298786A1 (en) * 2002-11-26 2004-06-18 Protein Design Labs, Inc. Methods of detecting soft tissue sarcoma, compositions and methods of screening for soft tissue sarcoma modulators
ITMI20031942A1 (it) 2003-10-09 2005-04-10 Indena Spa Dna codificante p185^neu e suoi usi terapeutici

Also Published As

Publication number Publication date
ES2370540T3 (es) 2011-12-19
CN101886090B (zh) 2012-09-26
RU2383620C2 (ru) 2010-03-10
US20110256162A1 (en) 2011-10-20
US8207141B2 (en) 2012-06-26
AU2005293218A1 (en) 2006-04-20
ATE524494T1 (de) 2011-09-15
CN101065399A (zh) 2007-10-31
WO2006040660A2 (en) 2006-04-20
EP1939217B1 (en) 2011-09-14
JP2008516596A (ja) 2008-05-22
JP5597346B2 (ja) 2014-10-01
HRP20110729T1 (hr) 2011-11-30
US20090214577A1 (en) 2009-08-27
HK1150627A1 (en) 2012-01-06
IL182510A0 (en) 2007-09-20
PL1939217T3 (pl) 2012-02-29
CA2583499C (en) 2013-12-03
AU2005293218B2 (en) 2011-11-17
ITMI20041965A1 (it) 2005-01-15
NO344353B1 (no) 2019-11-11
CA2583499A1 (en) 2006-04-20
RU2007117894A (ru) 2008-11-20
KR101337706B1 (ko) 2013-12-06
SG148195A1 (en) 2008-12-31
CN101886090A (zh) 2010-11-17
DK1939217T3 (da) 2011-11-21
US7985582B2 (en) 2011-07-26
SI1939217T1 (sl) 2012-01-31
EP1939217A3 (en) 2008-09-03
ZA200703875B (en) 2008-08-27
WO2006040660A3 (en) 2006-06-15
PT1939217E (pt) 2011-11-08
KR20070085298A (ko) 2007-08-27
EP1939217A2 (en) 2008-07-02
EP1809668A2 (en) 2007-07-25

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