DK1939217T3 - Plasmider kodende for p185neu-proteinsekvensvarianter og terapeutiske anvendelser deraf - Google Patents

Plasmider kodende for p185neu-proteinsekvensvarianter og terapeutiske anvendelser deraf

Info

Publication number
DK1939217T3
DK1939217T3 DK08004513.1T DK08004513T DK1939217T3 DK 1939217 T3 DK1939217 T3 DK 1939217T3 DK 08004513 T DK08004513 T DK 08004513T DK 1939217 T3 DK1939217 T3 DK 1939217T3
Authority
DK
Denmark
Prior art keywords
protein sequence
sequence variants
therapeutic uses
plasmids encoding
p185neu
Prior art date
Application number
DK08004513.1T
Other languages
English (en)
Inventor
Augusto Amici
Cristina Marchini
Elena Quaglino
Federica Cavallo
Guido Forni
Original Assignee
Augusto Amici
Cristina Marchini
Elena Quaglino
Federica Cavallo
Guido Forni
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Augusto Amici, Cristina Marchini, Elena Quaglino, Federica Cavallo, Guido Forni filed Critical Augusto Amici
Application granted granted Critical
Publication of DK1939217T3 publication Critical patent/DK1939217T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A61K39/001103—Receptors for growth factors
    • A61K39/001106—Her-2/neu/ErbB2, Her-3/ErbB3 or Her 4/ErbB4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)
DK08004513.1T 2004-10-15 2005-10-13 Plasmider kodende for p185neu-proteinsekvensvarianter og terapeutiske anvendelser deraf DK1939217T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001965A ITMI20041965A1 (it) 2004-10-15 2004-10-15 "dna codificante forme tronche e chimeriche della proteina p185neu e suoi usi terapeutici"
EP05795953A EP1809668A2 (en) 2004-10-15 2005-10-13 Plasmids coding for p185neu protein sequence variants and therapeutic uses thereof

Publications (1)

Publication Number Publication Date
DK1939217T3 true DK1939217T3 (da) 2011-11-21

Family

ID=35539028

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08004513.1T DK1939217T3 (da) 2004-10-15 2005-10-13 Plasmider kodende for p185neu-proteinsekvensvarianter og terapeutiske anvendelser deraf

Country Status (22)

Country Link
US (2) US7985582B2 (da)
EP (2) EP1809668A2 (da)
JP (1) JP5597346B2 (da)
KR (1) KR101337706B1 (da)
CN (2) CN101886090B (da)
AT (1) ATE524494T1 (da)
AU (1) AU2005293218B2 (da)
CA (1) CA2583499C (da)
DK (1) DK1939217T3 (da)
ES (1) ES2370540T3 (da)
HK (1) HK1150627A1 (da)
HR (1) HRP20110729T1 (da)
IL (1) IL182510A0 (da)
IT (1) ITMI20041965A1 (da)
NO (1) NO344353B1 (da)
PL (1) PL1939217T3 (da)
PT (1) PT1939217E (da)
RU (1) RU2383620C2 (da)
SG (1) SG148195A1 (da)
SI (1) SI1939217T1 (da)
WO (1) WO2006040660A2 (da)
ZA (1) ZA200703875B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101638440B (zh) * 2008-07-29 2011-10-26 中国人民解放军军事医学科学院基础医学研究所 一种可诱发机体抗肿瘤免疫的异种抗原-Fc融合蛋白及其应用
EP2777711A1 (en) 2013-03-11 2014-09-17 Icon Genetics GmbH Her2/Neu cancer vaccine
US11667960B2 (en) * 2016-04-20 2023-06-06 Arizona Board Of Regents On Behalf Of The University Of Arizona Methods and systems for RNA or DNA detection and sequencing

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5518885A (en) * 1994-04-19 1996-05-21 The United States Of America As Represented By The Department Of Health & Human Services ERBB2 promoter binding protein in neoplastic disease
US7820180B2 (en) * 2004-09-24 2010-10-26 The Trustees Of The University Of Pennsylvania Listeria-based and LLO-based vaccines
US7794729B2 (en) * 1994-11-08 2010-09-14 The Trustees Of The University Of Pennsylvania Methods and compositions for immunotherapy of cancer
CZ20012587A3 (cs) * 1999-01-29 2002-05-15 Corixa Corporation Izolovaný protein, nukleová kyselina, virový vektor, farmaceutický prostředek, izolovaná populace T buněk, způsob posílení imunitní odpovědi, způsob odstranění nádorových buněk, způsob stimulace a/nebo namnoľení T buněk a způsob přípravy fúzního proteinu
US20020177551A1 (en) 2000-05-31 2002-11-28 Terman David S. Compositions and methods for treatment of neoplastic disease
AU2003286770A1 (en) * 2002-10-30 2004-06-07 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services METHODS FOR PROPHYLAXIS AND TREATMENT OF HER-2/neu TUMORS
DE10251520A1 (de) * 2002-11-04 2004-05-13 Valeo Wischersysteme Gmbh Adapter für ein Wischblatt
AU2003298786A1 (en) * 2002-11-26 2004-06-18 Protein Design Labs, Inc. Methods of detecting soft tissue sarcoma, compositions and methods of screening for soft tissue sarcoma modulators
ITMI20031942A1 (it) 2003-10-09 2005-04-10 Indena Spa Dna codificante p185^neu e suoi usi terapeutici

Also Published As

Publication number Publication date
ES2370540T3 (es) 2011-12-19
CN101886090B (zh) 2012-09-26
RU2383620C2 (ru) 2010-03-10
US20110256162A1 (en) 2011-10-20
US8207141B2 (en) 2012-06-26
AU2005293218A1 (en) 2006-04-20
ATE524494T1 (de) 2011-09-15
CN101065399A (zh) 2007-10-31
WO2006040660A2 (en) 2006-04-20
EP1939217B1 (en) 2011-09-14
JP2008516596A (ja) 2008-05-22
JP5597346B2 (ja) 2014-10-01
HRP20110729T1 (hr) 2011-11-30
US20090214577A1 (en) 2009-08-27
HK1150627A1 (en) 2012-01-06
IL182510A0 (en) 2007-09-20
PL1939217T3 (pl) 2012-02-29
CA2583499C (en) 2013-12-03
AU2005293218B2 (en) 2011-11-17
ITMI20041965A1 (it) 2005-01-15
NO344353B1 (no) 2019-11-11
CA2583499A1 (en) 2006-04-20
RU2007117894A (ru) 2008-11-20
KR101337706B1 (ko) 2013-12-06
SG148195A1 (en) 2008-12-31
CN101886090A (zh) 2010-11-17
US7985582B2 (en) 2011-07-26
SI1939217T1 (sl) 2012-01-31
EP1939217A3 (en) 2008-09-03
ZA200703875B (en) 2008-08-27
WO2006040660A3 (en) 2006-06-15
NO20072457L (no) 2007-07-13
PT1939217E (pt) 2011-11-08
KR20070085298A (ko) 2007-08-27
EP1939217A2 (en) 2008-07-02
EP1809668A2 (en) 2007-07-25

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