NO20071658L - Alkil-pyridiner som 11-beta-inhibitorer for diabetes - Google Patents

Alkil-pyridiner som 11-beta-inhibitorer for diabetes

Info

Publication number
NO20071658L
NO20071658L NO20071658A NO20071658A NO20071658L NO 20071658 L NO20071658 L NO 20071658L NO 20071658 A NO20071658 A NO 20071658A NO 20071658 A NO20071658 A NO 20071658A NO 20071658 L NO20071658 L NO 20071658L
Authority
NO
Norway
Prior art keywords
diabetes
beta inhibitors
alkyl pyridines
pyridines
alkyl
Prior art date
Application number
NO20071658A
Other languages
English (en)
Norwegian (no)
Inventor
Werner Neidhart
Bernd Kuhn
Alexander Mayweg
Kurt Amrein
Daniel Hunziker
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35276680&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20071658(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20071658L publication Critical patent/NO20071658L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/76—Nitrogen atoms to which a second hetero atom is attached
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
NO20071658A 2004-10-04 2007-03-29 Alkil-pyridiner som 11-beta-inhibitorer for diabetes NO20071658L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04104856 2004-10-04
PCT/EP2005/010372 WO2006037501A1 (en) 2004-10-04 2005-09-26 Alkil-pyridines as 11-beta inhibitors for diabetes

Publications (1)

Publication Number Publication Date
NO20071658L true NO20071658L (no) 2007-05-03

Family

ID=35276680

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20071658A NO20071658L (no) 2004-10-04 2007-03-29 Alkil-pyridiner som 11-beta-inhibitorer for diabetes

Country Status (19)

Country Link
US (1) US7482341B2 (de)
EP (1) EP1799647A1 (de)
JP (2) JP5414990B2 (de)
KR (1) KR100874313B1 (de)
CN (1) CN101035762B (de)
AR (1) AR054688A1 (de)
AU (1) AU2005291561B2 (de)
BR (1) BRPI0516454A (de)
CA (1) CA2582276C (de)
HK (1) HK1108283A1 (de)
IL (1) IL182310A0 (de)
MX (1) MX2007003913A (de)
MY (1) MY139522A (de)
NO (1) NO20071658L (de)
NZ (1) NZ554014A (de)
RU (1) RU2383533C2 (de)
TW (1) TWI298721B (de)
WO (1) WO2006037501A1 (de)
ZA (1) ZA200702716B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2582276C (en) * 2004-10-04 2011-09-13 F. Hoffmann-La Roche Ag Alkil-pyridines as 11-beta inhibitors for diabetes
WO2006106423A2 (en) * 2005-04-07 2006-10-12 Pfizer Inc. Amino sulfonyl derivatives as inhibitors of human 11-.beta.-hydrosysteroid dehydrogenase
CN101218235A (zh) * 2005-05-10 2008-07-09 沃泰克斯药物股份有限公司 作为离子通道调控剂的二环衍生物
EA200702498A1 (ru) * 2005-06-16 2008-06-30 Пфайзер Инк. N-(пиридин-2-ил)сульфонамидные производные
PE20110235A1 (es) 2006-05-04 2011-04-14 Boehringer Ingelheim Int Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
PL2094663T3 (pl) * 2006-09-21 2011-07-29 Piramal Life Sciences Ltd Pochodne pirydyny do leczenia zaburzeń matabolicznych związanych z insulinoopornością lub hiperglikemią
CA2734710A1 (en) * 2007-08-22 2009-02-26 Proteologics Ltd. Pyrimidine and pyridine derivatives as posh and posh-ap inhibitors
US8114868B2 (en) * 2008-07-25 2012-02-14 Boehringer Ingelheim International Gmbh Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1
US8871208B2 (en) * 2009-12-04 2014-10-28 Abbvie Inc. 11-β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors and uses thereof
US20130158035A1 (en) * 2010-08-24 2013-06-20 Brigham Young University Antimetastatic compounds
EP2687507B1 (de) * 2011-03-14 2016-03-09 Taisho Pharmaceutical Co., Ltd. Stickstoffhaltige kondensierte heterocyclische verbindung
TW201512171A (zh) 2013-04-19 2015-04-01 Pfizer Ltd 化學化合物
CN104974084A (zh) * 2015-07-19 2015-10-14 佛山市赛维斯医药科技有限公司 一类胺基二吡啶叔醇结构的11β-HSD1抑制剂及其用途
TW201811766A (zh) 2016-08-29 2018-04-01 瑞士商諾華公司 N-(吡啶-2-基)吡啶-磺醯胺衍生物及其用於疾病治療之用途
RU2652993C1 (ru) * 2017-06-07 2018-05-04 федеральное государственное бюджетное образовательное учреждение высшего образования "Волгоградский государственный медицинский университет" Министерства здравоохранения Российской Федерации Новое 2-стирилпроизводное 4-(2,6-диметил-4-оксо-5-фенил-4н-пиримидин-1-ил)-бензсульфамида, обладающее эндотелеопротекторной активностью
EP4361131A1 (de) * 2021-06-21 2024-05-01 Iregene Therapeutics Ltd Oct4-aktivator mit hoher selektivität

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0001899D0 (sv) * 2000-05-22 2000-05-22 Pharmacia & Upjohn Ab New compounds
CN1633428A (zh) * 2001-11-22 2005-06-29 比奥维特罗姆股份公司 11－β－羟基类固醇脱氢酶1型抑制剂
CA2466491A1 (en) * 2001-11-22 2003-05-30 Biovitrum Ab Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1
TW200503994A (en) * 2003-01-24 2005-02-01 Novartis Ag Organic compounds
EP1606282B1 (de) * 2003-02-24 2008-11-12 Arena Pharmaceuticals, Inc. Phenyl- und pyridylpiperidinderivate als modulatoren des glucose-metabolismus
JPWO2005040135A1 (ja) * 2003-10-24 2007-03-08 小野薬品工業株式会社 抗ストレス薬およびその医薬用途
CN1897944A (zh) * 2003-12-19 2007-01-17 辉瑞有限公司 用于治疗糖尿病和肥胖症的11－β－羟基类固醇脱氢酶－1型(11－β－HSD－1 ) 抑制剂苯磺酰胺基－吡啶－2－基衍生物和相关化合物
OA13344A (en) * 2003-12-19 2007-04-13 Pfizer Benzenesulfonylamino-pyridin-2-yl derivatives and related compounds as inhibitors of 11-beta-hydroxysteroid dehydrogenase type 1 (11-beta-HSD-1) for the treatment of diabetes and obesity.
CA2582276C (en) * 2004-10-04 2011-09-13 F. Hoffmann-La Roche Ag Alkil-pyridines as 11-beta inhibitors for diabetes

Also Published As

Publication number Publication date
CA2582276A1 (en) 2006-04-13
AR054688A1 (es) 2007-07-11
US20060074237A1 (en) 2006-04-06
JP2008515826A (ja) 2008-05-15
US7482341B2 (en) 2009-01-27
ZA200702716B (en) 2008-07-30
JP5351199B2 (ja) 2013-11-27
HK1108283A1 (en) 2008-05-02
IL182310A0 (en) 2007-07-24
CN101035762A (zh) 2007-09-12
AU2005291561A1 (en) 2006-04-13
WO2006037501A9 (en) 2007-08-02
EP1799647A1 (de) 2007-06-27
RU2007116431A (ru) 2008-11-10
JP2011157373A (ja) 2011-08-18
NZ554014A (en) 2010-06-25
KR100874313B1 (ko) 2008-12-18
CN101035762B (zh) 2010-09-29
KR20070063527A (ko) 2007-06-19
CA2582276C (en) 2011-09-13
MX2007003913A (es) 2007-05-21
TWI298721B (en) 2008-07-11
AU2005291561B2 (en) 2010-02-25
MY139522A (en) 2009-10-30
WO2006037501A1 (en) 2006-04-13
RU2383533C2 (ru) 2010-03-10
JP5414990B2 (ja) 2014-02-12
TW200616958A (en) 2006-06-01
BRPI0516454A (pt) 2008-09-02

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application