NO20065052L - Krystallinsk polymorf av et bazedoksifenacetat - Google Patents
Krystallinsk polymorf av et bazedoksifenacetatInfo
- Publication number
- NO20065052L NO20065052L NO20065052A NO20065052A NO20065052L NO 20065052 L NO20065052 L NO 20065052L NO 20065052 A NO20065052 A NO 20065052A NO 20065052 A NO20065052 A NO 20065052A NO 20065052 L NO20065052 L NO 20065052L
- Authority
- NO
- Norway
- Prior art keywords
- crystalline polymorph
- bazedoxifene acetate
- bazedoxifene
- acetate
- polymorph
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Dermatology (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Foreliggende oppfinnelse angår en krystallinsk polymorf av bazedoksifenacetat, preparater inneholdende denne, fremstilling derav og anvendelse derav.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US56058204P | 2004-04-07 | 2004-04-07 | |
US66017805P | 2005-03-10 | 2005-03-10 | |
PCT/US2005/011724 WO2005100316A1 (en) | 2004-04-07 | 2005-04-06 | Crystalline polymorph of a bazedoxifene acetate |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20065052L true NO20065052L (no) | 2006-11-06 |
Family
ID=34966308
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20065052A NO20065052L (no) | 2004-04-07 | 2006-11-02 | Krystallinsk polymorf av et bazedoksifenacetat |
Country Status (18)
Country | Link |
---|---|
US (1) | US7683051B2 (no) |
EP (1) | EP1732890A1 (no) |
JP (2) | JP2007532560A (no) |
KR (1) | KR20060135866A (no) |
AR (1) | AR048527A1 (no) |
AU (1) | AU2005233133A1 (no) |
BR (1) | BRPI0509191A (no) |
CA (1) | CA2561010A1 (no) |
CR (1) | CR8615A (no) |
EC (1) | ECSP066911A (no) |
IL (1) | IL178236A0 (no) |
NO (1) | NO20065052L (no) |
PA (1) | PA8629101A1 (no) |
PE (1) | PE20060676A1 (no) |
RU (1) | RU2006132180A (no) |
SG (1) | SG151331A1 (no) |
TW (1) | TWI346105B (no) |
WO (1) | WO2005100316A1 (no) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2007532548A (ja) | 2004-04-07 | 2007-11-15 | ワイス | バゼドキシフェンアセテートの結晶質多形体 |
RU2006132180A (ru) | 2004-04-07 | 2008-05-20 | Вайет (Us) | Кристаллический полиморф базедоксифен ацетата |
US10645562B2 (en) | 2004-09-21 | 2020-05-05 | Agis Software Development Llc | Method to provide ad hoc and password protected digital and voice networks |
US8538393B1 (en) | 2004-09-21 | 2013-09-17 | Advanced Ground Information Systems, Inc. | Method to provide ad hoc and password protected digital and voice networks |
CA2613102A1 (en) * | 2005-06-29 | 2007-01-04 | Wyeth | Formulations of conjugated estrogens and bazedoxifene |
CN101304731B (zh) | 2005-08-24 | 2012-06-20 | 惠氏公司 | 醋酸苯卓昔芬制剂及其生产方法 |
PE20090100A1 (es) * | 2007-03-30 | 2009-02-26 | Wyeth Corp | Metodos de separacion y deteccion de acetato de bacedoxifeno en composiciones farmaceuticas |
CZ302358B6 (cs) * | 2007-07-25 | 2011-03-30 | Zentiva, A. S. | Nové soli bazedoxifenu |
WO2009102778A1 (en) * | 2008-02-11 | 2009-08-20 | Wyeth | Amorphous polymorph of bazedoxifene acetate |
CA2714494A1 (en) * | 2008-02-11 | 2009-08-20 | Wyeth Llc | Methods of preparing polymorphic form a of bazedoxifene acetate |
US20100016582A1 (en) * | 2008-02-11 | 2010-01-21 | Wyeth | Methods of converting polymorphic form b of bazedoxifene acetate to polymorphic form a of bazedoxifene acetate |
ITMI20091109A1 (it) | 2009-06-23 | 2010-12-24 | Wyeth Corp | Forma polimorfa d di bazedoxifene acetato e metodi per la sua preparazione |
ES2436841T3 (es) | 2009-10-27 | 2014-01-07 | Wyeth Llc | Formulaciones de bazedoxifeno con antioxidantes |
US8154175B2 (en) * | 2009-12-16 | 2012-04-10 | Hamilton Sundstrand Corporation | Sensing device |
EP2407467A1 (de) | 2010-07-14 | 2012-01-18 | Sandoz Ag | Kristalline Verbindung von 1-[4-(2-azepan-1-yl-ethoxy)-benzyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol und Milchsäure |
WO2012007453A1 (en) | 2010-07-14 | 2012-01-19 | Sandoz Ag | Crystalline compound of 1-[4-(2-azepan-1-ylethoxy)benzyl]-2-(4-hydroxyphenyl)-3-methyl-1h-indol-5-ol |
US9212172B2 (en) | 2010-09-14 | 2015-12-15 | Dr. Reddy's Laboratories Limited | Preparation of crystalline bazedoxifene and its salts |
EP2471770A1 (en) | 2010-12-28 | 2012-07-04 | Sandoz Ag | Method of preparing polymorphic pure form A of bazedoxifene acetate |
WO2013182170A1 (en) | 2012-06-07 | 2013-12-12 | Zentiva, K. S. | Enhancement of dissolution rate from pharmaceutical composition comprising bazedoxifene acetate |
WO2013182169A1 (en) | 2012-06-07 | 2013-12-12 | Zentiva, K. S. | Process of preparation of an antioxidant-free polymorphically and chemically stable formulation of bazedoxifene acetate |
WO2014186325A1 (en) | 2013-05-15 | 2014-11-20 | Indiana University Research And Technology Corporation | Processes and intermediates for preparing indole pharmaceuticals |
CN111060619B (zh) * | 2019-12-18 | 2022-11-18 | 北京鑫开元医药科技有限公司 | 一种醋酸巴多昔芬杂质的检测方法 |
US11246874B1 (en) | 2021-04-20 | 2022-02-15 | Oxygen Biotech LLC | Treatment of COVID-19 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW397821B (en) | 1996-04-19 | 2000-07-11 | American Home Produits Corp | 3-[4-(2-phenyl-indole-1-ylmethyl)-phenyl]-acrylamides and 2-phenyl-1-[4-(amino-1-yl-alk-1-ynyl)-benzyl]-1H-indol-5-ol as well as pharmaceutical compositions of estrogenic agents thereof |
US5880137A (en) | 1996-04-19 | 1999-03-09 | American Home Products Corporation | 2-phenyl-1- 4-(amino-1-yl-alk-1-ynyl)-benzyl!-1H-indol-5-ols as estrogenic agents |
US5780497A (en) | 1996-04-19 | 1998-07-14 | American Home Products Corporation | 2-phenyl-1- 4-(amino-1-yl-alk-1-ynyl)-benzyl!-1H-indol-5-ols as estrogenic agents |
PT802183E (pt) | 1996-04-19 | 2002-03-28 | American Home Prod | Agentes estrogenicos |
US5998402A (en) * | 1996-04-19 | 1999-12-07 | American Home Products Corporation | 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indoles as estrogenic agents |
ES2281937T3 (es) * | 1997-10-15 | 2007-10-01 | Wyeth | Nuevas ariloxi-alquil-dialquilaminas. |
US6005102A (en) | 1997-10-15 | 1999-12-21 | American Home Products Corporation | Aryloxy-alkyl-dialkylamines |
US6479535B1 (en) | 1998-05-15 | 2002-11-12 | Wyeth | 2-phenyl-1-[4-(2-aminoethoxy)-benzyl]-indole and estrogen formulations |
AR029538A1 (es) | 2000-07-06 | 2003-07-02 | Wyeth Corp | Composiciones farmaceuticas de agentes estrogenicos |
EP1336602A1 (en) | 2002-02-13 | 2003-08-20 | Giovanni Scaramuzzino | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases |
IL165395A0 (en) * | 2002-06-25 | 2006-01-15 | Wyeth Corp | Use of thio-oxubdile derivatives in treatment of hormone-related conditions |
RU2006132180A (ru) | 2004-04-07 | 2008-05-20 | Вайет (Us) | Кристаллический полиморф базедоксифен ацетата |
-
2005
- 2005-04-06 RU RU2006132180/04A patent/RU2006132180A/ru not_active Application Discontinuation
- 2005-04-06 BR BRPI0509191-8A patent/BRPI0509191A/pt not_active IP Right Cessation
- 2005-04-06 AR ARP050101367A patent/AR048527A1/es unknown
- 2005-04-06 WO PCT/US2005/011724 patent/WO2005100316A1/en active Application Filing
- 2005-04-06 PE PE2005000386A patent/PE20060676A1/es not_active Application Discontinuation
- 2005-04-06 JP JP2007507487A patent/JP2007532560A/ja not_active Abandoned
- 2005-04-06 EP EP05738044A patent/EP1732890A1/en not_active Withdrawn
- 2005-04-06 TW TW094110850A patent/TWI346105B/zh active
- 2005-04-06 KR KR1020067020649A patent/KR20060135866A/ko not_active Application Discontinuation
- 2005-04-06 CA CA002561010A patent/CA2561010A1/en not_active Abandoned
- 2005-04-06 PA PA20058629101A patent/PA8629101A1/es unknown
- 2005-04-06 AU AU2005233133A patent/AU2005233133A1/en not_active Withdrawn
- 2005-04-06 SG SG200902227-8A patent/SG151331A1/en unknown
- 2005-04-06 US US11/100,983 patent/US7683051B2/en active Active
-
2006
- 2006-09-12 CR CR8615A patent/CR8615A/es not_active Application Discontinuation
- 2006-09-21 IL IL178236A patent/IL178236A0/en unknown
- 2006-10-06 EC EC2006006911A patent/ECSP066911A/es unknown
- 2006-11-02 NO NO20065052A patent/NO20065052L/no not_active Application Discontinuation
-
2008
- 2008-06-30 JP JP2008171135A patent/JP2009035535A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
RU2006132180A (ru) | 2008-05-20 |
KR20060135866A (ko) | 2006-12-29 |
JP2007532560A (ja) | 2007-11-15 |
BRPI0509191A (pt) | 2007-09-25 |
TWI346105B (en) | 2011-08-01 |
CR8615A (es) | 2007-06-06 |
ECSP066911A (es) | 2006-12-20 |
AR048527A1 (es) | 2006-05-03 |
PE20060676A1 (es) | 2006-07-24 |
EP1732890A1 (en) | 2006-12-20 |
US7683051B2 (en) | 2010-03-23 |
PA8629101A1 (es) | 2005-11-25 |
CA2561010A1 (en) | 2005-10-27 |
SG151331A1 (en) | 2009-04-30 |
IL178236A0 (en) | 2006-12-31 |
TW200606149A (en) | 2006-02-16 |
WO2005100316A1 (en) | 2005-10-27 |
AU2005233133A1 (en) | 2005-10-27 |
JP2009035535A (ja) | 2009-02-19 |
US20050227965A1 (en) | 2005-10-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |