NO20063807L - Heterodimere follikkelstimulerende hormon-Fc(FSH-Fc)fusjonsproteiner for behandling av infertilitet - Google Patents
Heterodimere follikkelstimulerende hormon-Fc(FSH-Fc)fusjonsproteiner for behandling av infertilitetInfo
- Publication number
- NO20063807L NO20063807L NO20063807A NO20063807A NO20063807L NO 20063807 L NO20063807 L NO 20063807L NO 20063807 A NO20063807 A NO 20063807A NO 20063807 A NO20063807 A NO 20063807A NO 20063807 L NO20063807 L NO 20063807L
- Authority
- NO
- Norway
- Prior art keywords
- fsh
- fusion proteins
- treatment
- heterodimeric
- infertility
- Prior art date
Links
- 102000037865 fusion proteins Human genes 0.000 title abstract 3
- 108020001507 fusion proteins Proteins 0.000 title abstract 3
- 102000012673 Follicle Stimulating Hormone Human genes 0.000 title 1
- 108010079345 Follicle Stimulating Hormone Proteins 0.000 title 1
- 229940028334 follicle stimulating hormone Drugs 0.000 title 1
- 208000000509 infertility Diseases 0.000 title 1
- 230000036512 infertility Effects 0.000 title 1
- 231100000535 infertility Toxicity 0.000 title 1
- 102100026120 IgG receptor FcRn large subunit p51 Human genes 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 101710177940 IgG receptor FcRn large subunit p51 Proteins 0.000 abstract 2
- 102000018071 Immunoglobulin Fc Fragments Human genes 0.000 abstract 2
- 108010091135 Immunoglobulin Fc Fragments Proteins 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 108060003951 Immunoglobulin Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000035558 fertility Effects 0.000 abstract 1
- 102000018358 immunoglobulin Human genes 0.000 abstract 1
- 108010068617 neonatal Fc receptor Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54023604P | 2004-01-28 | 2004-01-28 | |
PCT/US2005/003034 WO2005073383A2 (en) | 2004-01-28 | 2005-01-27 | HETERODIMERIC FOLLICLE STIMULATING HORMONE-Fc (FSH-Fc) FUSION PROTEINS FOR THE TREATMENT OF INFERTILITY |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20063807L true NO20063807L (no) | 2006-10-25 |
Family
ID=34826205
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20063807A NO20063807L (no) | 2004-01-28 | 2006-08-25 | Heterodimere follikkelstimulerende hormon-Fc(FSH-Fc)fusjonsproteiner for behandling av infertilitet |
Country Status (10)
Country | Link |
---|---|
US (2) | US7601516B2 (zh) |
EP (1) | EP1711610A2 (zh) |
JP (1) | JP2008504012A (zh) |
CN (1) | CN1926237A (zh) |
AU (1) | AU2005207960A1 (zh) |
BR (1) | BRPI0507174A (zh) |
CA (1) | CA2553187A1 (zh) |
IL (2) | IL177049A (zh) |
NO (1) | NO20063807L (zh) |
WO (1) | WO2005073383A2 (zh) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8029803B2 (en) * | 2002-06-20 | 2011-10-04 | Paladin Labs, Inc. | Chimeric antigens for eliciting an immune response |
US8025873B2 (en) | 2002-06-20 | 2011-09-27 | Paladin Labs, Inc. | Chimeric antigens for eliciting an immune response |
US8007805B2 (en) * | 2003-08-08 | 2011-08-30 | Paladin Labs, Inc. | Chimeric antigens for breaking host tolerance to foreign antigens |
US8110665B2 (en) | 2003-11-13 | 2012-02-07 | Hanmi Holdings Co., Ltd. | Pharmaceutical composition comprising an immunoglobulin FC region as a carrier |
JP4870569B2 (ja) | 2003-11-13 | 2012-02-08 | ハンミ ホールディングス カンパニー リミテッド | 免疫グロブリン断片を用いた蛋白質結合体およびその製造方法 |
WO2005072097A2 (en) * | 2003-12-16 | 2005-08-11 | University Of Massachusetts | Toll-like receptor 9 modulators |
EP1711610A2 (en) | 2004-01-28 | 2006-10-18 | Syntonix Pharmaceuticals, Inc. | HETERODIMERIC FOLLICLE STIMULATING HORMONE-Fc (FSH-Fc) FUSION PROTEINS FOR THE TREATMENT OF INFERTILITY |
GB0510627D0 (en) | 2005-05-25 | 2005-06-29 | Avidex Ltd | Polypeptides |
CN101300355A (zh) * | 2005-10-13 | 2008-11-05 | 威瑞克斯医药公司 | 包含丙型肝炎病毒多肽和用于引起免疫应答的Fc片段的嵌合抗原 |
CN103071209A (zh) | 2005-11-17 | 2013-05-01 | 周吉尼克斯股份有限公司 | 用无针注射递送粘稠制剂 |
EP1801121A1 (en) * | 2005-12-23 | 2007-06-27 | CONARIS research institute AG | Soluble gp130 molecule variants useful as a medicament |
US8268347B1 (en) | 2006-10-24 | 2012-09-18 | Aradigm Corporation | Dual action, inhaled formulations providing both an immediate and sustained release profile |
ES2693697T3 (es) * | 2007-11-30 | 2018-12-13 | Aspenbio Pharma, Inc. | Actividad de la hormona folículo estimulante equina recombinante |
WO2009080764A2 (en) * | 2007-12-20 | 2009-07-02 | Abylnx N.V. | Oral or nasal administration of compounds comprising amino acid sequences |
AR081755A1 (es) * | 2010-04-02 | 2012-10-17 | Hanmi Holdings Co Ltd | Formulacion de accion prolongada de la hormona estimuladora de los foliculos donde se usa un fragmento de inmunoglobulina, metodo de preparacion y metodo para tratar a un sujeto que sufre un trastorno reproductivo |
FR2958936A1 (fr) * | 2010-04-14 | 2011-10-21 | Sanofi Aventis | Proteine de fusion robo1-fc et son utilisation dans le traitement des tumeurs |
EP2707021B1 (en) * | 2011-05-09 | 2024-02-21 | Minerva Biotechnologies Corporation | Genetically engineered growth factor variants |
KR20140053991A (ko) * | 2011-07-18 | 2014-05-08 | 아츠 바이올로직스 에이/에스 | 장기간 작용하는 황체 형성 호르몬 (lh) 화합물 |
KR101967345B1 (ko) * | 2012-10-18 | 2019-04-09 | 삼성전자주식회사 | 안지오포이에틴-2와 인테그린 간의 결합을 저해하는 펩타이드 및 그 용도 |
CN103509121B (zh) | 2012-11-22 | 2015-01-28 | 苏州康宁杰瑞生物科技有限公司 | 一种fsh融合蛋白及其制备方法和用途 |
EA201591700A1 (ru) | 2013-03-14 | 2015-12-30 | Ридженерон Фармасьютикалз, Инк. | Гибридные белки апелина и их применение |
CN103539860B (zh) * | 2013-11-01 | 2014-12-03 | 广州优联康医药科技有限公司 | 一种长效重组人促卵泡激素融合蛋白 |
CN103539862B (zh) * | 2013-11-01 | 2015-04-01 | 广州联康生物科技有限公司 | 一种长效重组促卵泡激素及其应用 |
KR20160086942A (ko) | 2013-11-20 | 2016-07-20 | 리제너론 파아마슈티컬스, 인크. | Aplnr 조절물질 및 이들의 용도 |
CN104524553B (zh) * | 2014-12-12 | 2015-07-29 | 薛传校 | 一种长效促排卵注射液 |
CN107810202A (zh) * | 2015-02-17 | 2018-03-16 | 韩美药品株式会社 | 长效胰岛素或胰岛素类似物复合物 |
AU2016321146C1 (en) * | 2015-09-08 | 2021-10-28 | Theripion, Inc. | ApoA-1 fusion polypeptides and related compositions and methods |
CN105567733B (zh) * | 2016-01-11 | 2019-04-23 | 佛山安普泽生物医药股份有限公司 | CHO细胞表达凝血酶-Fc融合蛋白的方法 |
CN106046176B (zh) | 2016-08-16 | 2019-09-10 | 中国药科大学 | 一种高活性长效降糖融合蛋白及其制备方法与医药用途 |
CN107082815A (zh) * | 2017-06-28 | 2017-08-22 | 杭州皓阳生物技术有限公司 | 一种fsh‑hsa融合蛋白及其制备方法 |
CN107540748B (zh) | 2017-09-15 | 2020-07-14 | 北京伟杰信生物科技有限公司 | 长效重组猪fsh融合蛋白及其制备方法与应用 |
CN110305903B (zh) * | 2019-07-31 | 2021-10-01 | 江苏璟泽生物医药有限公司 | 重组人促卵泡激素及其制备方法 |
CN113599503A (zh) * | 2021-07-28 | 2021-11-05 | 安徽中起生物科技有限公司 | 一种调节卵巢功能的生物制剂及其制备方法和应用 |
CN115975043A (zh) * | 2021-09-30 | 2023-04-18 | 宁波三生生物科技股份有限公司 | 重组促卵泡激素融合蛋白 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4713339A (en) * | 1983-01-19 | 1987-12-15 | Genentech, Inc. | Polycistronic expression vector construction |
US4840896A (en) * | 1983-11-02 | 1989-06-20 | Integrated Genetics, Inc. | Heteropolymeric protein |
DE68926888T2 (de) * | 1988-01-22 | 1997-01-09 | Zymogenetics Inc | Verfahren zur Herstellung von sekretierten Rezeptoranalogen |
US5338835A (en) * | 1989-02-21 | 1994-08-16 | Washington University | CTP-extended form of FSH |
US5225538A (en) * | 1989-02-23 | 1993-07-06 | Genentech, Inc. | Lymphocyte homing receptor/immunoglobulin fusion proteins |
EP1132471A3 (de) * | 1989-09-12 | 2001-11-28 | F. Hoffmann-La Roche Ag | TNF-bindende Proteine |
EP0533006A1 (en) * | 1991-09-18 | 1993-03-24 | F.Hoffmann-La Roche & Co. Aktiengesellschaft | Chimaeric interleukin 5-receptor/immunoglobulin polypeptides |
CA2131003A1 (en) * | 1992-05-26 | 1993-12-09 | Raymond G. Goodwin | Novel cytokine that binds cd30 |
US6086875A (en) * | 1995-01-17 | 2000-07-11 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of immunogens |
US6485726B1 (en) * | 1995-01-17 | 2002-11-26 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of therapeutics |
US6030613A (en) * | 1995-01-17 | 2000-02-29 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of therapeutics |
US5739277A (en) * | 1995-04-14 | 1998-04-14 | Genentech Inc. | Altered polypeptides with increased half-life |
US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
UA52646C2 (uk) * | 1996-02-20 | 2003-01-15 | Еплайд Рісьорч Системз Ерс Холдінг Н.В. | Гібридні білки, фармацевтична композиція, що містить гібридний білок, ізольована молекула днк, що містить гібридний білок, вектор експресії, клітина-хазяїн, спосіб продукування гібридного білка, спосіб індукування визрівання фолікулів |
EP0904107B1 (en) | 1996-03-18 | 2004-10-20 | Board Of Regents, The University Of Texas System | Immunoglobin-like domains with increased half lives |
ATE329911T1 (de) * | 1998-08-07 | 2006-07-15 | Applied Research Systems | Fsh mimetika zur behandlung von infertilität |
US7081446B2 (en) * | 2002-01-31 | 2006-07-25 | The Trustees Of Columbia University In The City Of New York | Long-acting follicle stimulating hormone analogues and uses thereof |
US20040063912A1 (en) * | 2002-03-15 | 2004-04-01 | The Brigham And Women's Hospital, Inc. | Central airway administration for systemic delivery of therapeutics |
CA2479212A1 (en) * | 2002-03-15 | 2003-09-25 | Brigham And Women's Hospital, Inc. | Central airway administration for systemic delivery of therapeutics |
AU2003232081B2 (en) * | 2002-07-03 | 2009-02-05 | Brandeis University | Central airway administration for systemic delivery of therapeutics |
US6936574B2 (en) * | 2002-08-30 | 2005-08-30 | Halliburton Energy Services, Inc. | Process for controlling gas migration during well cementing |
EP1711610A2 (en) * | 2004-01-28 | 2006-10-18 | Syntonix Pharmaceuticals, Inc. | HETERODIMERIC FOLLICLE STIMULATING HORMONE-Fc (FSH-Fc) FUSION PROTEINS FOR THE TREATMENT OF INFERTILITY |
-
2005
- 2005-01-27 EP EP05712467A patent/EP1711610A2/en not_active Withdrawn
- 2005-01-27 US US11/045,022 patent/US7601516B2/en not_active Expired - Fee Related
- 2005-01-27 WO PCT/US2005/003034 patent/WO2005073383A2/en active Application Filing
- 2005-01-27 CA CA002553187A patent/CA2553187A1/en not_active Abandoned
- 2005-01-27 BR BRPI0507174-7A patent/BRPI0507174A/pt not_active IP Right Cessation
- 2005-01-27 CN CNA2005800062581A patent/CN1926237A/zh active Pending
- 2005-01-27 JP JP2006551550A patent/JP2008504012A/ja active Pending
- 2005-01-27 AU AU2005207960A patent/AU2005207960A1/en not_active Abandoned
-
2006
- 2006-07-24 IL IL177049A patent/IL177049A/en not_active IP Right Cessation
- 2006-08-25 NO NO20063807A patent/NO20063807L/no not_active Application Discontinuation
-
2009
- 2009-04-21 US US12/427,640 patent/US8293707B2/en active Active
-
2010
- 2010-06-21 IL IL206518A patent/IL206518A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
US20100291079A1 (en) | 2010-11-18 |
AU2005207960A1 (en) | 2005-08-11 |
CA2553187A1 (en) | 2005-08-11 |
EP1711610A2 (en) | 2006-10-18 |
US20050186662A1 (en) | 2005-08-25 |
WO2005073383A3 (en) | 2005-11-24 |
US8293707B2 (en) | 2012-10-23 |
IL206518A0 (en) | 2010-12-30 |
IL177049A (en) | 2010-11-30 |
US7601516B2 (en) | 2009-10-13 |
BRPI0507174A (pt) | 2008-04-01 |
WO2005073383A2 (en) | 2005-08-11 |
IL177049A0 (en) | 2006-12-10 |
JP2008504012A (ja) | 2008-02-14 |
CN1926237A (zh) | 2007-03-07 |
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Legal Events
Date | Code | Title | Description |
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |