NO20063807L - Heterodimere follikkelstimulerende hormon-Fc(FSH-Fc)fusjonsproteiner for behandling av infertilitet - Google Patents
Heterodimere follikkelstimulerende hormon-Fc(FSH-Fc)fusjonsproteiner for behandling av infertilitetInfo
- Publication number
- NO20063807L NO20063807L NO20063807A NO20063807A NO20063807L NO 20063807 L NO20063807 L NO 20063807L NO 20063807 A NO20063807 A NO 20063807A NO 20063807 A NO20063807 A NO 20063807A NO 20063807 L NO20063807 L NO 20063807L
- Authority
- NO
- Norway
- Prior art keywords
- fsh
- fusion proteins
- treatment
- heterodimeric
- infertility
- Prior art date
Links
- 102000037865 fusion proteins Human genes 0.000 title abstract 3
- 108020001507 fusion proteins Proteins 0.000 title abstract 3
- 102000012673 Follicle Stimulating Hormone Human genes 0.000 title 1
- 108010079345 Follicle Stimulating Hormone Proteins 0.000 title 1
- 229940028334 follicle stimulating hormone Drugs 0.000 title 1
- 208000000509 infertility Diseases 0.000 title 1
- 230000036512 infertility Effects 0.000 title 1
- 231100000535 infertility Toxicity 0.000 title 1
- 102100026120 IgG receptor FcRn large subunit p51 Human genes 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 101710177940 IgG receptor FcRn large subunit p51 Proteins 0.000 abstract 2
- 102000018071 Immunoglobulin Fc Fragments Human genes 0.000 abstract 2
- 108010091135 Immunoglobulin Fc Fragments Proteins 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 108060003951 Immunoglobulin Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000035558 fertility Effects 0.000 abstract 1
- 102000018358 immunoglobulin Human genes 0.000 abstract 1
- 108010068617 neonatal Fc receptor Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Plant Pathology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Toxicology (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54023604P | 2004-01-28 | 2004-01-28 | |
| PCT/US2005/003034 WO2005073383A2 (en) | 2004-01-28 | 2005-01-27 | HETERODIMERIC FOLLICLE STIMULATING HORMONE-Fc (FSH-Fc) FUSION PROTEINS FOR THE TREATMENT OF INFERTILITY |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20063807L true NO20063807L (no) | 2006-10-25 |
Family
ID=34826205
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20063807A NO20063807L (no) | 2004-01-28 | 2006-08-25 | Heterodimere follikkelstimulerende hormon-Fc(FSH-Fc)fusjonsproteiner for behandling av infertilitet |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7601516B2 (https=) |
| EP (1) | EP1711610A2 (https=) |
| JP (1) | JP2008504012A (https=) |
| CN (1) | CN1926237A (https=) |
| AU (1) | AU2005207960A1 (https=) |
| BR (1) | BRPI0507174A (https=) |
| CA (1) | CA2553187A1 (https=) |
| IL (2) | IL177049A (https=) |
| NO (1) | NO20063807L (https=) |
| WO (1) | WO2005073383A2 (https=) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8025873B2 (en) * | 2002-06-20 | 2011-09-27 | Paladin Labs, Inc. | Chimeric antigens for eliciting an immune response |
| US8029803B2 (en) * | 2002-06-20 | 2011-10-04 | Paladin Labs, Inc. | Chimeric antigens for eliciting an immune response |
| US8007805B2 (en) | 2003-08-08 | 2011-08-30 | Paladin Labs, Inc. | Chimeric antigens for breaking host tolerance to foreign antigens |
| ATE555133T1 (de) | 2003-11-13 | 2012-05-15 | Hanmi Holdings Co Ltd | Igg fc fragment für einen arzneimittelträger und verfahren zu dessen herstellung |
| US8110665B2 (en) | 2003-11-13 | 2012-02-07 | Hanmi Holdings Co., Ltd. | Pharmaceutical composition comprising an immunoglobulin FC region as a carrier |
| US20050255451A1 (en) * | 2003-12-16 | 2005-11-17 | Eicke Latz | Toll-like receptor 9 modulators |
| JP2008504012A (ja) | 2004-01-28 | 2008-02-14 | シントニックス・ファーマシューティカルズ・インコーポレーテッド | 不妊治療のためのへテロ二量体卵胞刺激ホルモン−Fc(FSH−Fc)融合タンパク質 |
| GB0510627D0 (en) | 2005-05-25 | 2005-06-29 | Avidex Ltd | Polypeptides |
| KR20080056301A (ko) * | 2005-10-13 | 2008-06-20 | 바이렉스 메디칼 코포레이션 | 면역 반응을 유도시키기 위한, C형 간염 바이러스폴리펩티드 및 Fc 단편을 함유하는 키메라 항원 |
| WO2007061896A1 (en) | 2005-11-17 | 2007-05-31 | Zogenix, Inc. | Delivery of viscous formulations by needle-free injection |
| EP1801121A1 (en) * | 2005-12-23 | 2007-06-27 | CONARIS research institute AG | Soluble gp130 molecule variants useful as a medicament |
| US8268347B1 (en) | 2006-10-24 | 2012-09-18 | Aradigm Corporation | Dual action, inhaled formulations providing both an immediate and sustained release profile |
| CA2707352C (en) * | 2007-11-30 | 2020-10-27 | Aspenbio Pharma, Inc. | Activity of recombinant equine follicle stimulating hormone |
| WO2009080764A2 (en) * | 2007-12-20 | 2009-07-02 | Abylnx N.V. | Oral or nasal administration of compounds comprising amino acid sequences |
| AR081755A1 (es) * | 2010-04-02 | 2012-10-17 | Hanmi Holdings Co Ltd | Formulacion de accion prolongada de la hormona estimuladora de los foliculos donde se usa un fragmento de inmunoglobulina, metodo de preparacion y metodo para tratar a un sujeto que sufre un trastorno reproductivo |
| FR2958936A1 (fr) * | 2010-04-14 | 2011-10-21 | Sanofi Aventis | Proteine de fusion robo1-fc et son utilisation dans le traitement des tumeurs |
| EP2686418A4 (en) | 2011-03-17 | 2015-04-22 | Minerva Biotechnologies Corp | METHOD FOR THE PRODUCTION OF PLURIPOTENTAL STEM CELLS |
| EP2707021B1 (en) * | 2011-05-09 | 2024-02-21 | Minerva Biotechnologies Corporation | Genetically engineered growth factor variants |
| KR20140053991A (ko) * | 2011-07-18 | 2014-05-08 | 아츠 바이올로직스 에이/에스 | 장기간 작용하는 황체 형성 호르몬 (lh) 화합물 |
| KR101967345B1 (ko) * | 2012-10-18 | 2019-04-09 | 삼성전자주식회사 | 안지오포이에틴-2와 인테그린 간의 결합을 저해하는 펩타이드 및 그 용도 |
| CN103509121B (zh) * | 2012-11-22 | 2015-01-28 | 苏州康宁杰瑞生物科技有限公司 | 一种fsh融合蛋白及其制备方法和用途 |
| WO2014152955A1 (en) * | 2013-03-14 | 2014-09-25 | Regeneron Pharmaceuticals, Inc. | Apelin fusion proteins and uses thereof |
| CN103539860B (zh) * | 2013-11-01 | 2014-12-03 | 广州优联康医药科技有限公司 | 一种长效重组人促卵泡激素融合蛋白 |
| CN103539862B (zh) * | 2013-11-01 | 2015-04-01 | 广州联康生物科技有限公司 | 一种长效重组促卵泡激素及其应用 |
| CN105916881A (zh) | 2013-11-20 | 2016-08-31 | 瑞泽恩制药公司 | Aplnr调节剂及其用途 |
| CN104524553B (zh) * | 2014-12-12 | 2015-07-29 | 薛传校 | 一种长效促排卵注射液 |
| US10894089B2 (en) * | 2015-02-17 | 2021-01-19 | Hanmi Pharm. Co., Ltd. | Long-acting insulin or insulin analogue conjugate |
| WO2017044424A1 (en) * | 2015-09-08 | 2017-03-16 | Theripion, Inc. | Apoa-1 fusion polypeptides and related compositions and methods |
| CN105567733B (zh) * | 2016-01-11 | 2019-04-23 | 佛山安普泽生物医药股份有限公司 | CHO细胞表达凝血酶-Fc融合蛋白的方法 |
| CN106046176B (zh) * | 2016-08-16 | 2019-09-10 | 中国药科大学 | 一种高活性长效降糖融合蛋白及其制备方法与医药用途 |
| CN107082815A (zh) * | 2017-06-28 | 2017-08-22 | 杭州皓阳生物技术有限公司 | 一种fsh‑hsa融合蛋白及其制备方法 |
| CN107540748B (zh) * | 2017-09-15 | 2020-07-14 | 北京伟杰信生物科技有限公司 | 长效重组猪fsh融合蛋白及其制备方法与应用 |
| CN110305903B (zh) * | 2019-07-31 | 2021-10-01 | 江苏璟泽生物医药有限公司 | 重组人促卵泡激素及其制备方法 |
| CN113599503A (zh) * | 2021-07-28 | 2021-11-05 | 安徽中起生物科技有限公司 | 一种调节卵巢功能的生物制剂及其制备方法和应用 |
| CN115975043B (zh) * | 2021-09-30 | 2024-07-12 | 宁波三生生物科技股份有限公司 | 重组促卵泡激素融合蛋白 |
| CN115947860B (zh) * | 2022-07-06 | 2025-04-25 | 华兰基因工程有限公司 | 一种重组人促卵泡生成素Fc融合蛋白及制备方法 |
| CN116768979B (zh) * | 2022-07-06 | 2025-04-29 | 华兰基因工程有限公司 | 一种重组人促卵泡生成素CTP-Fc融合蛋白及制备方法 |
| WO2025140545A1 (zh) * | 2023-12-28 | 2025-07-03 | 江苏众红生物工程创药研究院有限公司 | 新型长效人fsh与lh融合蛋白及其制备方法与应用 |
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| US4713339A (en) | 1983-01-19 | 1987-12-15 | Genentech, Inc. | Polycistronic expression vector construction |
| US4840896A (en) | 1983-11-02 | 1989-06-20 | Integrated Genetics, Inc. | Heteropolymeric protein |
| DE68926888T2 (de) | 1988-01-22 | 1997-01-09 | Zymogenetics Inc | Verfahren zur Herstellung von sekretierten Rezeptoranalogen |
| US5338835A (en) | 1989-02-21 | 1994-08-16 | Washington University | CTP-extended form of FSH |
| US5225538A (en) | 1989-02-23 | 1993-07-06 | Genentech, Inc. | Lymphocyte homing receptor/immunoglobulin fusion proteins |
| ATE194384T1 (de) | 1989-09-12 | 2000-07-15 | Hoffmann La Roche | Tnf-bindende proteine |
| EP0533006A1 (en) | 1991-09-18 | 1993-03-24 | F.Hoffmann-La Roche & Co. Aktiengesellschaft | Chimaeric interleukin 5-receptor/immunoglobulin polypeptides |
| DE69334070T2 (de) | 1992-05-26 | 2007-01-04 | Immunex Corp., Thousand Oaks | Neue zytokine die cd30 binden |
| US6086875A (en) | 1995-01-17 | 2000-07-11 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of immunogens |
| US6485726B1 (en) | 1995-01-17 | 2002-11-26 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of therapeutics |
| US6030613A (en) | 1995-01-17 | 2000-02-29 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of therapeutics |
| US5739277A (en) | 1995-04-14 | 1998-04-14 | Genentech Inc. | Altered polypeptides with increased half-life |
| US6096871A (en) | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
| ATE295887T1 (de) | 1996-02-20 | 2005-06-15 | Applied Research Systems | Heterodimerebildende hybrid-proteine |
| JP4046354B2 (ja) | 1996-03-18 | 2008-02-13 | ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム | 増大した半減期を有する免疫グロブリン様ドメイン |
| CA2339018A1 (en) | 1998-08-07 | 2000-02-17 | Applied Research Systems Ars Holding N.V. | Fsh mimetics for the treatment of infertility |
| US7081446B2 (en) | 2002-01-31 | 2006-07-25 | The Trustees Of Columbia University In The City Of New York | Long-acting follicle stimulating hormone analogues and uses thereof |
| AU2002316574B2 (en) * | 2002-03-15 | 2008-05-01 | Brandeis University | Central airway administration for systemic delivery of therapeutics |
| US20040063912A1 (en) | 2002-03-15 | 2004-04-01 | The Brigham And Women's Hospital, Inc. | Central airway administration for systemic delivery of therapeutics |
| AU2003232081B2 (en) | 2002-07-03 | 2009-02-05 | Brandeis University | Central airway administration for systemic delivery of therapeutics |
| US6936574B2 (en) * | 2002-08-30 | 2005-08-30 | Halliburton Energy Services, Inc. | Process for controlling gas migration during well cementing |
| JP2008504012A (ja) | 2004-01-28 | 2008-02-14 | シントニックス・ファーマシューティカルズ・インコーポレーテッド | 不妊治療のためのへテロ二量体卵胞刺激ホルモン−Fc(FSH−Fc)融合タンパク質 |
-
2005
- 2005-01-27 JP JP2006551550A patent/JP2008504012A/ja active Pending
- 2005-01-27 BR BRPI0507174-7A patent/BRPI0507174A/pt not_active IP Right Cessation
- 2005-01-27 AU AU2005207960A patent/AU2005207960A1/en not_active Abandoned
- 2005-01-27 US US11/045,022 patent/US7601516B2/en not_active Expired - Fee Related
- 2005-01-27 WO PCT/US2005/003034 patent/WO2005073383A2/en not_active Ceased
- 2005-01-27 CA CA002553187A patent/CA2553187A1/en not_active Abandoned
- 2005-01-27 EP EP05712467A patent/EP1711610A2/en not_active Withdrawn
- 2005-01-27 CN CNA2005800062581A patent/CN1926237A/zh active Pending
-
2006
- 2006-07-24 IL IL177049A patent/IL177049A/en not_active IP Right Cessation
- 2006-08-25 NO NO20063807A patent/NO20063807L/no not_active Application Discontinuation
-
2009
- 2009-04-21 US US12/427,640 patent/US8293707B2/en not_active Expired - Fee Related
-
2010
- 2010-06-21 IL IL206518A patent/IL206518A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1926237A (zh) | 2007-03-07 |
| EP1711610A2 (en) | 2006-10-18 |
| US20100291079A1 (en) | 2010-11-18 |
| IL177049A0 (en) | 2006-12-10 |
| BRPI0507174A (pt) | 2008-04-01 |
| IL177049A (en) | 2010-11-30 |
| JP2008504012A (ja) | 2008-02-14 |
| WO2005073383A3 (en) | 2005-11-24 |
| US20050186662A1 (en) | 2005-08-25 |
| US8293707B2 (en) | 2012-10-23 |
| US7601516B2 (en) | 2009-10-13 |
| IL206518A0 (en) | 2010-12-30 |
| WO2005073383A2 (en) | 2005-08-11 |
| AU2005207960A1 (en) | 2005-08-11 |
| CA2553187A1 (en) | 2005-08-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |