NO20063138L - Hydronopolderivater som agonister i human ORL1 receptorer - Google Patents

Hydronopolderivater som agonister i human ORL1 receptorer

Info

Publication number
NO20063138L
NO20063138L NO20063138A NO20063138A NO20063138L NO 20063138 L NO20063138 L NO 20063138L NO 20063138 A NO20063138 A NO 20063138A NO 20063138 A NO20063138 A NO 20063138A NO 20063138 L NO20063138 L NO 20063138L
Authority
NO
Norway
Prior art keywords
hydronopoly
derivatives
agonists
receptors
human orl1
Prior art date
Application number
NO20063138A
Other languages
English (en)
Inventor
Matthias Mentzel
Dania B Reiche
Reinhard Bruckner
Samuel David
Bartholomeus J Van Steen
Uwe Schon
Daniel Jasserand
Ulf Preuschoff
Original Assignee
Solvay Pharm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2004/053373 external-priority patent/WO2005058890A2/en
Application filed by Solvay Pharm Gmbh filed Critical Solvay Pharm Gmbh
Publication of NO20063138L publication Critical patent/NO20063138L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Det beskrives en gruppe av hydronopolderivater som er agonister på human ORL1 (nociceptin)-reseptorer. Det beskrives videre fremstilling av disse forbindelser til farmasøytiske preparater inneholdende en farmakologisk aktiv mengde av minst et av disse nye hydronopolderivater som aktiv bestanddel, så vel som bruken av disse farmasøytiske preparater for behandling av forstyrrelser der ORLl-reseptorer er involvert. Oppfinnelsen angår således forbindelser med den generelle formel (1) der symbolene har de betydninger som er gitt i beskrivelsen.
NO20063138A 2003-12-12 2006-07-06 Hydronopolderivater som agonister i human ORL1 receptorer NO20063138L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US52870103P 2003-12-12 2003-12-12
EP03104662 2003-12-12
PCT/EP2004/053373 WO2005058890A2 (en) 2003-12-12 2004-12-09 Hydronopol derivatives as agonists on human orl1 receptors

Publications (1)

Publication Number Publication Date
NO20063138L true NO20063138L (no) 2006-09-06

Family

ID=34702351

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20063138A NO20063138L (no) 2003-12-12 2006-07-06 Hydronopolderivater som agonister i human ORL1 receptorer

Country Status (3)

Country Link
KR (1) KR20060123473A (no)
IL (1) IL175347A0 (no)
NO (1) NO20063138L (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115124441B (zh) * 2022-06-30 2024-04-02 南京林业大学 一类诺卜酸酰肼类化合物的制备方法和产品及其应用

Also Published As

Publication number Publication date
IL175347A0 (en) 2006-09-05
KR20060123473A (ko) 2006-12-01

Similar Documents

Publication Publication Date Title
NO20050397L (no) Tricykliske steroidhormonnukleaere reseptormodulatorer
UA83862C2 (ru) Производные тиазола как модуляторы рецепторов канабиноидов
EA200600811A1 (ru) НОВЫЕ ПРОИЗВОДНЫЕ ТЕТРАГИДРОСПИРО {ПИПЕРИДИН-2,7'-ПИРРОЛО [3,2-b]ПИРИДИНА} И НОВЫЕ ПРОИЗВОДНЫЕ ИНДОЛА, ПРИМЕНЕНИЕ ДЛЯ ЛЕЧЕНИЯ РАССТРОЙСТВ, СВЯЗАННЫХ С 5-HT-РЕЦЕПТОРОМ
NO20052496L (no) Selekterte CGRP antagonister, fremgangsmater for fremstilling derav og anvendelse derav som medikamenter.
NO20092342L (no) Azaspiroderivativater
NO20050134L (no) Difenylazetidioner substituert med syregrupper, fremgangsmate for fremstilling av disse, medikamenter inneholdende disse forbindelser og deres anvendelse
NO20065060L (no) Farmasoytiske kombinasjoner inneholdende benzoksazin for behandling av respiratoriske forstyrrelser
NO20080670L (no) Substituerte piperaziner som metabotrofiske glutamatreseptorantagonister
UA84896C2 (ru) Производные гидронопола как агонисты человеческих рецепторов orl1
IL176546A0 (en) Imidazoline derivatives having cb1-antagonistic activity
NO20045486L (no) Nye forbindelser og deres anvendelse
WO2004089366A8 (en) Bicyclic compounds as nr2b receptor antagonists
NO20091766L (no) Spiro-piperidinderivater
MA34094B1 (fr) Dérivés de 3-(hétéroarylamino)-1,2,3,4-tétrahydro-9h-carbazole et leur utilisation comme modulateurs du récepteur de la prostaglandine d2
WO2007125398A3 (en) : sulfonamide compounds as antagonists of the n-type calcium channel
MXPA06003374A (es) Derivados de bencimidazolona y quinazolinona como agonistas en receptores semejantes al receptor opioide 1 de humano.
NO20075637L (no) 4-fenyl-5-okso-1,4,5,6,7,8-heksahydrokinolinderivater som medikamenter for behandling av infertilitet
NO20091831L (no) Indoler
NO20060969L (no) Benzoxazinon avledende sulfonamid forbindelser, deres fremstilling og anvedelse som medikamenter
SE0303480D0 (sv) Benzofuranes
NO20052491L (no) Nye vitronektinresepotr antagonistderivater, fremgangsmate til deres fremstilling, anvendelse derav som legemidler og farmasoytiske sammensetninger som inneholder de samme
NO20080671L (no) Bisykliske piperaziner som metabotrofiske glutamatreseptorantagonister
NO20091830L (no) Spiro-piperidinderivater som VIa reseptorantagonister
TW200519102A (en) Hydronopol substituted benzimidazolone and quinazolinone derivatives as agonists on human ORL1 receptors
NO20092264L (no) Spiro-piperidinderivater

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application