NO20063064L - Ny anvendelse av peptidforbindelser for behandling av sentralneurotisk smerte - Google Patents

Ny anvendelse av peptidforbindelser for behandling av sentralneurotisk smerte

Info

Publication number
NO20063064L
NO20063064L NO20063064A NO20063064A NO20063064L NO 20063064 L NO20063064 L NO 20063064L NO 20063064 A NO20063064 A NO 20063064A NO 20063064 A NO20063064 A NO 20063064A NO 20063064 L NO20063064 L NO 20063064L
Authority
NO
Norway
Prior art keywords
treatment
central
peptide compounds
new use
neurotic pain
Prior art date
Application number
NO20063064A
Other languages
English (en)
Norwegian (no)
Inventor
Thomas Stohr
Original Assignee
Sanol Arznei Schwarz Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP03027742A external-priority patent/EP1537862A1/fr
Application filed by Sanol Arznei Schwarz Gmbh filed Critical Sanol Arznei Schwarz Gmbh
Publication of NO20063064L publication Critical patent/NO20063064L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/03—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20063064A 2003-12-02 2006-06-30 Ny anvendelse av peptidforbindelser for behandling av sentralneurotisk smerte NO20063064L (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP03027742A EP1537862A1 (fr) 2003-12-02 2003-12-02 Nouvelle utilisation de peptides pour le traitement de la douleur neuropathique centrale
US53089503P 2003-12-22 2003-12-22
EP03029632 2003-12-22
PCT/EP2004/013729 WO2005053667A1 (fr) 2003-12-02 2004-12-02 Nouvelle utilisation de composes peptidiques pour le traitement de la douleur neuropathique centrale

Publications (1)

Publication Number Publication Date
NO20063064L true NO20063064L (no) 2006-09-01

Family

ID=34657533

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20063064A NO20063064L (no) 2003-12-02 2006-06-30 Ny anvendelse av peptidforbindelser for behandling av sentralneurotisk smerte

Country Status (17)

Country Link
US (1) US7794987B2 (fr)
EP (1) EP1689378B1 (fr)
JP (1) JP4664924B2 (fr)
KR (1) KR20060111524A (fr)
AT (1) ATE428413T1 (fr)
AU (1) AU2004294714B2 (fr)
BR (1) BRPI0417101A (fr)
CA (1) CA2545543A1 (fr)
DE (1) DE602004020657D1 (fr)
EA (1) EA013590B1 (fr)
ES (1) ES2325995T3 (fr)
HK (1) HK1095749A1 (fr)
IL (1) IL175770A0 (fr)
NO (1) NO20063064L (fr)
NZ (1) NZ546576A (fr)
PL (1) PL1689378T3 (fr)
WO (1) WO2005053667A1 (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE327744T1 (de) 2001-03-20 2006-06-15 Sanol Arznei Schwarz Gmbh Neue verwendung von peptidverbindungen bei der behandlung von nicht-neuropathischem entzündungsschmerz
ATE228358T1 (de) 2001-03-21 2002-12-15 Sanol Arznei Schwarz Gmbh Neue verwendung einer klasse von peptidverbindungen zur behandlung von allodynie oder andere arten von chronischen oder phantomschmerzen
KR20060111524A (ko) 2003-12-02 2006-10-27 쉬바르츠파르마에이지 펩타이드 화합물들의 중추 신경병증성 통증 치료를 위한신규한 용도
US20070042969A1 (en) * 2004-03-26 2007-02-22 Srz Properties, Inc. Combination therapy for pain in painful diabetic neuropathy
US20100256179A1 (en) * 2004-03-26 2010-10-07 Ucb Pharma Gmbh Combination therapy for pain in painful diabetic neuropathy
EP1579858A1 (fr) * 2004-03-26 2005-09-28 Schwarz Pharma Ag Nouvelle utilisation de peptides pour le traitement de la neuropathie diabètique
NZ550482A (en) * 2004-04-16 2010-08-27 Sanol Arznei Schwarz Gmbh Use of peptidic compounds for the prophylaxis and treatment of chronic headache
EP1604655A1 (fr) 2004-06-09 2005-12-14 Schwarz Pharma Ag Utilisation nouvelle de peptides pour le traitement de neuralgies trigeminales
BRPI0514721A (pt) * 2004-08-27 2008-06-24 Sanol Arznei Schwarz Gmbh uso de compostos de peptìdeos para tratar dor de cáncer ósseo, dor induzida por quimioterapia e nucleosìdeo
EP1642889A1 (fr) * 2004-10-02 2006-04-05 Schwarz Pharma Ag Route de synthèse améliorée pour lacosamide
US20060252749A1 (en) * 2005-01-28 2006-11-09 Srz Properties, Inc. Lacosamide for add-on therapy of psychosis
US20070043120A1 (en) * 2005-08-18 2007-02-22 Bettina Beyreuther Therapeutic combination for painful medical conditions
EP1754476A1 (fr) * 2005-08-18 2007-02-21 Schwarz Pharma Ag Lacosamide (SPM 927) pour le traitement de la myalgie, par exemple de la fibromyalgie
US7902401B2 (en) 2006-12-14 2011-03-08 Nps Pharmaceuticals, Inc. Fluorinated compounds
EA200802412A1 (ru) * 2006-06-08 2009-06-30 Шварц Фарма Аг Терапевтические комбинации для сопровождающихся болью медицинских состояний
EP1873527A1 (fr) * 2006-06-30 2008-01-02 Schwarz Pharma Ag Procédé d'identification des modulateurs CRMP
KR101518427B1 (ko) 2006-06-15 2015-05-08 유씨비 파르마 게엠베하 상승적 항경련 효과를 갖는 약제학적 조성물
CN101466390B (zh) 2006-06-15 2014-03-12 优时比制药有限公司 用于治疗难治性癫痫持续状态的肽类化合物
WO2008070994A1 (fr) 2006-12-14 2008-06-19 Nps Pharmaceuticals, Inc. Utilisation de dérivés de la d-sérine pour le traitement de troubles de l'anxiété
WO2009053070A1 (fr) 2007-10-23 2009-04-30 Schwarz Pharma Ag Composés pour le traitement de conditions de démyélinisation
CN102046652B (zh) * 2008-04-02 2014-11-05 赛诺菲-安万特 来自Actinomadura namibiensis的高度桥联的肽
EP2468261A1 (fr) 2010-12-02 2012-06-27 UCB Pharma GmbH Formulation de lacosamide
EP2645997B1 (fr) 2010-12-02 2022-08-10 UCB Pharma GmbH Formulation de lacosamide en prise quotidienne unique
KR20210115502A (ko) 2020-03-13 2021-09-27 (주)포에버엔케이 기능성 펩타이드를 함유하는 경피 통증 경감 주사액 조성물
KR20230042193A (ko) 2021-09-19 2023-03-28 (주)포에버엔케이 기능성 펩타이드를 함유하는 경피 통증 경감 주사액 조성물

Family Cites Families (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378729A (en) * 1985-02-15 1995-01-03 Research Corporation Technologies, Inc. Amino acid derivative anticonvulsant
US5654301A (en) * 1985-02-15 1997-08-05 Research Corporation Technologies, Inc. Amino acid derivative anticonvulsant
ATE166051T1 (de) 1987-08-01 1998-05-15 Takeda Chemical Industries Ltd Zwischenprodukte, ihre herstellung und verwendung zur herstellung alpha-ungesättigter amine
US5962490A (en) * 1987-09-25 1999-10-05 Texas Biotechnology Corporation Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
YU47834B (sr) 1989-08-10 1996-01-09 Schering Agrochemical Limited Azolni pesticid
TW217417B (fr) 1991-12-04 1993-12-11 Manyu Seiyaku Kk
US5585358A (en) * 1993-07-06 1996-12-17 Yissum Research Development Corporation Of The Hebrew University Of Jerusalem Derivatives of valproic acid amides and 2-valproenoic acid amides, method of making and use thereof as anticonvulsant agents
GB9504854D0 (en) * 1994-03-31 1995-04-26 Zeneca Ltd Nitrogen derivatives
US5760038A (en) * 1995-02-06 1998-06-02 Bristol-Myers Squibb Company Substituted biphenyl sulfonamide endothelin antagonists
US5849737A (en) * 1995-04-14 1998-12-15 The Regents Of The University Of California Compositions and methods for treating pain
WO1997003677A1 (fr) * 1995-07-24 1997-02-06 Trustees Of Boston University Inhibition de l'activite des recepteurs du n-methyl-d-aspartate au moyen de derives de sulfate de pregnenolone
US6114390A (en) * 1995-11-30 2000-09-05 Karl Thomae Gmbh Amino acid derivatives, pharmaceutical compositions containing these compounds and processes for preparing them
DE19544687A1 (de) 1995-11-30 1997-06-05 Thomae Gmbh Dr K Aminosäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US6037324A (en) * 1996-01-04 2000-03-14 Leukosite, Inc. Inhibitors of MAdCAM-1-mediated interactions and methods of use therefor
GB9601724D0 (en) * 1996-01-29 1996-03-27 Merck Sharp & Dohme Therapeutic agents
US5773475A (en) * 1997-03-17 1998-06-30 Research Corporation Technologies, Inc. Anticonvulsant enantiomeric amino acid derivatives
US6277825B1 (en) * 1996-07-22 2001-08-21 University Of Utah Research Foundation Use of conantokins for treating pain
KR100491282B1 (ko) * 1996-07-24 2005-05-24 워너-램버트 캄파니 엘엘씨 통증 치료용 이소부틸가바 및 그의 유도체
US6589994B1 (en) 1996-08-30 2003-07-08 Nps Pharmaceuticals, Inc. Treating a variety of pathological conditions, including spasticity and convulsions, by effecting a modulation of CNS activity with isovaleramide, isovaleric acid, or a related compound
US6048899A (en) * 1997-03-17 2000-04-11 Research Corporation Tech., Inc. Anticonvulsant enantiomeric amino acid derivatives
ATE320249T1 (de) 1997-07-08 2006-04-15 Ono Pharmaceutical Co Aminosäurederivate
JP4213339B2 (ja) * 1997-07-15 2009-01-21 リサーチ コーポレイション テクノロジーズ，インコーポレイテッド 発作を治療するのに有用なアミノ酸誘導体
US6737408B1 (en) * 1997-08-07 2004-05-18 University Of Cincinnati Compounds for control of appetite, blood pressure, cardiovascular response, libido, and circadian rhythm
WO1999007413A1 (fr) 1997-08-11 1999-02-18 Algos Pharmaceutical Corporation Inhibiteurs de la substance p associes a des inhibiteurs nmda pour traiter la douleur
US6492553B1 (en) * 1998-01-29 2002-12-10 Aventis Pharamaceuticals Inc. Methods for preparing N-[(aliphatic or aromatic)carbonyl)]-2-aminoaetamide compounds and for cyclizing such compounds
US6673832B1 (en) 1998-05-04 2004-01-06 Gudarz Davar Methods for identifying compounds for treating pain
GB9816228D0 (en) 1998-07-24 1998-09-23 Pfizer Ltd Isoquinolines
JP2002527362A (ja) * 1998-10-09 2002-08-27 ノバルテイス・アクチエンゲゼルシヤフト ノミに対するルフェヌロンおよびニテンピラムの経口用配合物
US7417038B1 (en) 1998-10-15 2008-08-26 Imperial Innovations Limited Methods of treating cachexia
ATE380180T1 (de) 1999-09-03 2007-12-15 Actelion Pharmaceuticals Ltd Bis-sulfonamiden
SE0001373D0 (sv) 2000-04-13 2000-04-13 Karolinska Innovations Ab NPY Y1 receptor agonists and antagonists
EP1160248A1 (fr) 2000-05-31 2001-12-05 Pfizer Inc. Dérivés du N-(isoxazol-5-yl)-sulfonamide et leur utilisation comme antagonistes de l'endothéline
MXPA03001458A (es) * 2000-08-17 2004-05-04 Teva Pharma Derivados de acido valproico para el tratamiento del dolor.
DE10041478A1 (de) 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
ATE375793T1 (de) * 2000-08-25 2007-11-15 Res Corp Technologies Inc Verwendungen von antikonvulsiven aminosäure zur behandlung bipolarer erkrankungen
US6821978B2 (en) * 2000-09-19 2004-11-23 Schering Corporation Xanthine phosphodiesterase V inhibitors
DE60134337D1 (de) 2000-11-21 2008-07-17 Ucb Pharma Sa N-alkylierte gaba verbindungen, verfahren zu deren
EG26979A (en) 2000-12-21 2015-03-01 Astrazeneca Ab Chemical compounds
CA2434495A1 (fr) 2001-01-30 2002-08-08 Merck & Co., Inc. Compositions ophtalmiques pouvant traiter l'hypertension oculaire
ATE327744T1 (de) * 2001-03-20 2006-06-15 Sanol Arznei Schwarz Gmbh Neue verwendung von peptidverbindungen bei der behandlung von nicht-neuropathischem entzündungsschmerz
ATE228358T1 (de) * 2001-03-21 2002-12-15 Sanol Arznei Schwarz Gmbh Neue verwendung einer klasse von peptidverbindungen zur behandlung von allodynie oder andere arten von chronischen oder phantomschmerzen
KR20040016844A (ko) 2001-03-27 2004-02-25 액테리온 파마슈티칼 리미티드 유로텐신 ⅱ 수용체 길항제인1,2,3,4-테트라하이드로이소퀴놀린 유도체
ITMI20011308A1 (it) 2001-06-21 2002-12-21 Nicox Sa Farmaci per il dolore cronico
FR2831820B1 (fr) 2001-11-05 2004-08-20 Ethypharm Sa Comprime orodispersible presentant une grande homogeneite et son procede de preparation
US7183259B2 (en) * 2002-05-17 2007-02-27 Xenoport Amino acid conjugates providing for sustained systemic concentrations of GABA analogues
GB0213669D0 (en) 2002-06-14 2002-07-24 Astrazeneca Ab Chemical compounds
AU2003276201A1 (en) 2002-11-11 2004-06-03 Bayer Healthcare Ag Phenyl or heteroaryl amino alkane derivatives as ip receptor antagonist
US7687080B2 (en) * 2002-11-25 2010-03-30 Taraxos Inc. Treatment of neuropathy
WO2004066987A2 (fr) 2003-01-30 2004-08-12 Dynogen Pharmaceuticals, Inc. Methodes destinees a traiter les troubles du tractus gastro-intestinal au moyen de modulateurs du canal sodique
JP2006515327A (ja) 2003-01-30 2006-05-25 ダイノジェン ファーマシューティカルズ， インコーポレイテッド ナトリウムチャネル調節因子を用いた下部尿路障害を処置するための方法
US20040266743A1 (en) 2003-05-09 2004-12-30 Pharmacia Corporation Combination of an aldosterone receptor antagonist and a renin inhibitor
US20070208166A1 (en) 2003-10-24 2007-09-06 Exelixis, Inc. Tao Kinase Modulators And Method Of Use
KR20060111524A (ko) 2003-12-02 2006-10-27 쉬바르츠파르마에이지 펩타이드 화합물들의 중추 신경병증성 통증 치료를 위한신규한 용도
EP1537862A1 (fr) 2003-12-02 2005-06-08 Schwarz Pharma Ag Nouvelle utilisation de peptides pour le traitement de la douleur neuropathique centrale
EP1541138A1 (fr) 2003-12-05 2005-06-15 Schwarz Pharma Ag Nouvelle utilisation de peptides pour le traitement de la status epilepticus et etats connexes
US20060009384A1 (en) * 2003-12-05 2006-01-12 David Rudd Novel use of peptide compounds for treating status epilepticus or related conditions
EP1579858A1 (fr) 2004-03-26 2005-09-28 Schwarz Pharma Ag Nouvelle utilisation de peptides pour le traitement de la neuropathie diabètique
US20070042969A1 (en) * 2004-03-26 2007-02-22 Srz Properties, Inc. Combination therapy for pain in painful diabetic neuropathy
US20050227961A1 (en) * 2004-04-08 2005-10-13 Vela Pharmaceuticals, Inc. Compositions and methods for treatment of neuropathic pain, fibromyalgia and chronic fatigue syndrome
NZ550482A (en) * 2004-04-16 2010-08-27 Sanol Arznei Schwarz Gmbh Use of peptidic compounds for the prophylaxis and treatment of chronic headache
EP1604654A1 (fr) * 2004-05-18 2005-12-14 Schwarz Pharma Ag Utilisation nouvelle de peptides pour le traitement des dyskynesies
EP1604655A1 (fr) 2004-06-09 2005-12-14 Schwarz Pharma Ag Utilisation nouvelle de peptides pour le traitement de neuralgies trigeminales
EP1604656A1 (fr) * 2004-06-09 2005-12-14 Schwarz Pharma Ag Utilisation nouvelle de peptides pour le traitement de la sclérose amytrophique latérale (ALS)
US7427601B2 (en) * 2004-06-24 2008-09-23 Schwarz Pharma Ag Method for treating tremor
BRPI0514721A (pt) * 2004-08-27 2008-06-24 Sanol Arznei Schwarz Gmbh uso de compostos de peptìdeos para tratar dor de cáncer ósseo, dor induzida por quimioterapia e nucleosìdeo
EP1642889A1 (fr) * 2004-10-02 2006-04-05 Schwarz Pharma Ag Route de synthèse améliorée pour lacosamide
US20060252749A1 (en) * 2005-01-28 2006-11-09 Srz Properties, Inc. Lacosamide for add-on therapy of psychosis
EP1688137A1 (fr) 2005-01-28 2006-08-09 Schwarz Pharma Ag SPM 927 pour la thérapie adjuvante de la schizophrenie
US20070043120A1 (en) * 2005-08-18 2007-02-22 Bettina Beyreuther Therapeutic combination for painful medical conditions
US20070048372A1 (en) * 2005-08-18 2007-03-01 Srz Properties, Inc. Method for treating non-inflammatory osteoarthritic pain
EP1754476A1 (fr) * 2005-08-18 2007-02-21 Schwarz Pharma Ag Lacosamide (SPM 927) pour le traitement de la myalgie, par exemple de la fibromyalgie

Also Published As

Publication number Publication date
IL175770A0 (en) 2006-09-05
JP4664924B2 (ja) 2011-04-06
ATE428413T1 (de) 2009-05-15
EA013590B1 (ru) 2010-06-30
WO2005053667A1 (fr) 2005-06-16
JP2007513119A (ja) 2007-05-24
EP1689378B1 (fr) 2009-04-15
HK1095749A1 (en) 2007-05-18
US7794987B2 (en) 2010-09-14
ES2325995T3 (es) 2009-09-28
EA200601074A1 (ru) 2006-10-27
CA2545543A1 (fr) 2005-06-16
AU2004294714B2 (en) 2009-12-10
NZ546576A (en) 2009-05-31
US20050209163A1 (en) 2005-09-22
DE602004020657D1 (de) 2009-05-28
PL1689378T3 (pl) 2009-09-30
KR20060111524A (ko) 2006-10-27
BRPI0417101A (pt) 2007-02-06
EP1689378A1 (fr) 2006-08-16
AU2004294714A1 (en) 2005-06-16

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