NO20062944L - Fremgangsmater for framstilling av stereoisomerisk berikede aminer - Google Patents

Fremgangsmater for framstilling av stereoisomerisk berikede aminer

Info

Publication number
NO20062944L
NO20062944L NO20062944A NO20062944A NO20062944L NO 20062944 L NO20062944 L NO 20062944L NO 20062944 A NO20062944 A NO 20062944A NO 20062944 A NO20062944 A NO 20062944A NO 20062944 L NO20062944 L NO 20062944L
Authority
NO
Norway
Prior art keywords
methods
stereoisomerically enriched
compound
preparing
cr7r8
Prior art date
Application number
NO20062944A
Other languages
English (en)
Inventor
Shanghui Hu
Carlos Alberto Martinez
Junhua Tao
Rida Daniel Yazbeck
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO20062944L publication Critical patent/NO20062944L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/08—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/24—Proline; Hydroxyproline; Histidine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/14—Nitrogen or oxygen as hetero atom and at least one other diverse hetero ring atom in the same ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Foreliggende oppfinnelse angår fremgangsmåter for fremstilling av en stereoisomerisk anriket forbindelse med formel (I), hvori R6 er hydrogen, som innbefatter behandling av en forbindelse med formel (I), hvori R6 er valgt fra C1-C10 alkyl, C2-C10 alkenyl, C2-C10 alkynyl, -(CR7R8)t(C6-Ci4 aryl) og -(CR7R8)t(4-10 leddet heterosyklisk forbindelse), og hvori nevnte C6-C14 aryl og 4-10 leddet hetrosyklisk forbindelse eventuelt substituert med minst en substituent valgt fra halo, C1-C10 alkyl, -OR og -N(R R ), med en biokatalysator i en vandig løsning, er organisk løsemiddel eller en blanding av organiske og vandige løsemidler hvori minst en stereoisomer blir selektivt hydrolysert.
NO20062944A 2003-12-04 2006-06-23 Fremgangsmater for framstilling av stereoisomerisk berikede aminer NO20062944L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52714303P 2003-12-04 2003-12-04
PCT/IB2004/003812 WO2005054186A2 (en) 2003-12-04 2004-11-22 Methods for the preparation of stereoisomerically enriched amines

Publications (1)

Publication Number Publication Date
NO20062944L true NO20062944L (no) 2006-09-04

Family

ID=34652482

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062944A NO20062944L (no) 2003-12-04 2006-06-23 Fremgangsmater for framstilling av stereoisomerisk berikede aminer

Country Status (14)

Country Link
US (1) US20050192441A1 (no)
EP (1) EP1737818A2 (no)
JP (1) JP2007521801A (no)
KR (1) KR20060100457A (no)
CN (1) CN101068780A (no)
AU (1) AU2004295187A1 (no)
BR (1) BRPI0417046A (no)
CA (1) CA2549289A1 (no)
CO (1) CO5700727A2 (no)
IL (1) IL175737A0 (no)
NO (1) NO20062944L (no)
RU (1) RU2006119470A (no)
WO (1) WO2005054186A2 (no)
ZA (1) ZA200604545B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007026875A1 (ja) * 2005-09-02 2007-03-08 Ube Industries, Ltd. 光学活性（Ｓ又はＲ）－α－ヒドロキシ酸及び光学活性（Ｒ又はＳ）－α－ヒドロキシ酸エステルの製造方法
CN101284797B (zh) * 2008-06-11 2010-08-11 常州恩滋生物科技有限公司 N-保护的烯丙基甘氨酸酯的拆分方法
EP2373977A1 (en) * 2008-12-17 2011-10-12 The Lubrizol Corporation Optically active functional fluid markers
RU2014106109A (ru) * 2011-07-20 2015-08-27 Эвоник Дегусса Гмбх Окисление и аминирование первичных спиртов

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5644028A (en) * 1992-05-13 1997-07-01 Japan Energy Corporation Process for producing peptide derivatives and salts therefor
US5932550A (en) * 1995-06-30 1999-08-03 Japan Energy Corporation Dipeptide compound or pharmaceutically acceptable salt thereof and medical use thereof
US6222043B1 (en) * 1995-06-30 2001-04-24 Japan Energy Corporation Methods of preparing novel dipeptide compounds or pharmaceutically acceptable salts thereof
CA2245543A1 (en) * 1996-03-13 1997-09-18 Fabienne Henzen Process for producing n-protected d-proline derivatives 8
AU5757498A (en) * 1996-12-16 1998-07-15 Lonza A.G. Method for production of d-proline derivatives
HN2002000136A (es) * 2001-06-11 2003-07-31 Basf Ag Inhibidores de la proteasa del virus hiv, compuestos que contienen a los mismos, sus usos farmaceuticos y los materiales para su sintesis

Also Published As

Publication number Publication date
ZA200604545B (en) 2007-10-31
JP2007521801A (ja) 2007-08-09
KR20060100457A (ko) 2006-09-20
IL175737A0 (en) 2006-09-05
WO2005054186A2 (en) 2005-06-16
US20050192441A1 (en) 2005-09-01
BRPI0417046A (pt) 2007-02-06
RU2006119470A (ru) 2007-12-20
CN101068780A (zh) 2007-11-07
EP1737818A2 (en) 2007-01-03
CO5700727A2 (es) 2006-11-30
AU2004295187A1 (en) 2005-06-16
WO2005054186A3 (en) 2007-04-19
CA2549289A1 (en) 2005-06-16

Similar Documents

Publication Publication Date Title
NO20055688L (no) Organiske forbindelser
NO20061406L (no) Organiske forbindelser
BRPI0513584A (pt) derivado de diamina, processo de preparação deste e fungicida compreendendo derivado de diamina como um ingrediente ativo
MY148566A (en) Crystalline solvates and complexes of (is) -1, 5- anhydro-1 -c-(3-( (phenyl) methyl) phenyl) -d-glucitol derivatives with amino acids as sglt2 inhibitors for the treatment of diabetes
PE20070051A1 (es) Serin-amidas sustituidas con heteroaroilo
PE20040155A1 (es) Derivados aminoinazoles, procedimiento de preparacion e intermedios de este procedimiento a titulo de medicamentos y composiciones farmaceuticas que los contienen
CA2383409A1 (en) Process for preparing 4"-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives
BRPI0510598A (pt) compostos de amida de aril ou heteroaril substituìdos
ATE539057T1 (de) Verfahren zur herstellung von disubstituiertem piperidin und zwischenprodukten davon
CO5580815A2 (es) Derivados de adamantana, procesos para su preparacion y composiciones farmaceuticas que los contienen
DK1740544T3 (da) 2 pyridinylcycloalkylcarboxamidderivater, der er egnede som fungicider
AR041297A1 (es) Derivados de 4-pirrolidino- fenil- bencil eter
NO20054135L (no) Kipolinon/benzoksazin derivater og anvendelser derav
DE602008001725D1 (de) 1-(1-benzylpiperidin-4-yl)benzimidazol-5-carbonsäurederivate zur behandlung von diabetes mellitus
NO20062944L (no) Fremgangsmater for framstilling av stereoisomerisk berikede aminer
MX2009008772A (es) Derivado piridil-triazolopirimidina o su sal, pesticida que lo contiene y proceso para su produccion.
DE602004002579D1 (de) Herstellung und verwendung von 2-substituierten 5-oxo-3-pyrazolidincarboxylaten
BR0211291A (pt) Derivados de diamina, processo para produção dos derivados de diamina e fungicidas contendo os derivados de diamina como ingrediente ativo
NO20076000L (no) Aminosyrederivater
PE20040750A1 (es) Derivados de n-(1-acetilpiperidin-4-il)-4-benzidril-2-isopropilpiperazin-1-carboxamida como inhibidores de 17beta-hidroxiesteroide deshidrogenasa de tipo 3
NO20045630L (no) Forbindelser for behandling av antraks og inhibering av letal faktor
MXPA04005940A (es) Acidos 3-(imidazolil)-2-aminopropanoicos.
CY1105158T1 (el) Εκδοχα πυριδοϊνδολονης που φερει υποκαταστατη στο -3 μια ετepοκυκλικη ομαδα, η παρασκευη τους και η εφαρμογη τους στη θepαπευτικη
NO20070972L (no) Benzyloksyderivater som MAOB-inhibitorer
TW200600012A (en) Fungicidal mixtures

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application