NO20061909L - 3-(4-aminofenyl)tienopyrimid-4-on derivater som MCH R-antagonister for behandling av fedme, diabetes,depresjon og angst - Google Patents

3-(4-aminofenyl)tienopyrimid-4-on derivater som MCH R-antagonister for behandling av fedme, diabetes,depresjon og angst

Info

Publication number
NO20061909L
NO20061909L NO20061909A NO20061909A NO20061909L NO 20061909 L NO20061909 L NO 20061909L NO 20061909 A NO20061909 A NO 20061909A NO 20061909 A NO20061909 A NO 20061909A NO 20061909 L NO20061909 L NO 20061909L
Authority
NO
Norway
Prior art keywords
mch
anxiety
obesity
antagonists
diabetes
Prior art date
Application number
NO20061909A
Other languages
English (en)
Norwegian (no)
Inventor
Anthony Louis Handlon
Donald L Hertzog
Clifton L Hyman
Kevin K Barvian
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of NO20061909L publication Critical patent/NO20061909L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20061909A 2003-10-23 2006-04-28 3-(4-aminofenyl)tienopyrimid-4-on derivater som MCH R-antagonister for behandling av fedme, diabetes,depresjon og angst NO20061909L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51380003P 2003-10-23 2003-10-23
PCT/US2004/034846 WO2005042541A1 (en) 2003-10-23 2004-10-21 3-(4-aminophenyl) thienopyrimid-4-one derivatives as mch r1 antagonists for the treatment of obesity, diabetes, depression and anxiety

Publications (1)

Publication Number Publication Date
NO20061909L true NO20061909L (no) 2006-05-03

Family

ID=34549304

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20061909A NO20061909L (no) 2003-10-23 2006-04-28 3-(4-aminofenyl)tienopyrimid-4-on derivater som MCH R-antagonister for behandling av fedme, diabetes,depresjon og angst

Country Status (15)

Country Link
US (1) US20070078125A1 (es)
EP (1) EP1678184A1 (es)
JP (1) JP2007509158A (es)
KR (1) KR20060100412A (es)
CN (1) CN1871242A (es)
AU (1) AU2004285913A1 (es)
BR (1) BRPI0415667A (es)
CA (1) CA2543122A1 (es)
CO (1) CO5690599A2 (es)
IL (1) IL174693A0 (es)
MA (1) MA28111A1 (es)
MX (1) MXPA06003997A (es)
NO (1) NO20061909L (es)
WO (1) WO2005042541A1 (es)
ZA (1) ZA200603181B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1907398A1 (en) * 2005-07-15 2008-04-09 AstraZeneca AB Therapeutic agents
CN101273026A (zh) 2005-09-30 2008-09-24 霍夫曼-拉罗奇有限公司 作为mch受体拮抗剂的茚满衍生物
US8618115B2 (en) * 2005-10-26 2013-12-31 Bristol-Myers Squibb Company Substituted thieno[3,2-d]pyrimidinones as MCHR1 antagonists and methods for using them
US7745447B2 (en) * 2005-10-26 2010-06-29 Bristol-Myers Squibb Company Substituted thieno[3,2-D]pyrimidines as non-basic melanin concentrating hormone receptor-1 antagonists
EP1966164B1 (en) 2005-12-21 2013-03-06 Janssen Pharmaceutica N.V. Novel substituted pyrazinone derivatives for use in mch-1 mediated diseases
US7553836B2 (en) 2006-02-06 2009-06-30 Bristol-Myers Squibb Company Melanin concentrating hormone receptor-1 antagonists
TW200801022A (en) 2006-02-15 2008-01-01 Sanofi Aventis Novel amino alcohol-substituted arylthienopyrimidinones, process for their preparation and their use as medicaments
CN101384555A (zh) * 2006-02-15 2009-03-11 塞诺菲-安万特股份有限公司 新的氨基醇取代的芳基二氢异喹啉酮类、其制备方法以及其作为药物的用途
BRPI0707869A2 (pt) * 2006-02-15 2011-05-10 Sanofi Aventis ariltienopirimidinonas substituÍdas com azaciclil, processo para a sua preparaÇço e seus usos como medicamentos
TW200800908A (en) * 2006-02-15 2008-01-01 Sanofi Aventis Novel azacyclyl-substituted aryldihydroisoquinolinones, process for their preparation and their use as medicaments
BRPI0712680A2 (pt) * 2006-06-08 2012-11-20 Lilly Co Eli antagonistas de receptor de mch
JP2010501553A (ja) 2006-08-18 2010-01-21 アストラゼネカ アクチボラグ Mchr1アンタゴニストとしてのチエノピリミジン−4−オン誘導体およびチエノピリダジン−7−オン誘導体
CN101679348A (zh) 2007-01-10 2010-03-24 阿尔巴尼分子研究公司 5-吡啶酮取代的吲唑
US7851622B2 (en) 2007-04-25 2010-12-14 Bristol-Myers Squibb Company Non-basic melanin concentrating hormone receptor-1 antagonists
BRPI0814772A2 (pt) 2007-07-21 2015-03-03 Albany Molecular Res Inc Indazóis substituídos por 5-piridinona
PE20091928A1 (es) 2008-05-29 2009-12-31 Bristol Myers Squibb Co Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos
US8278316B2 (en) 2009-03-09 2012-10-02 Bristol-Myers Squibb Company Aza pyridone analogs useful as melanin concentrating hormone receptor-1 antagonists
HUP1100241A3 (en) 2011-05-06 2013-12-30 Richter Gedeon Nyrt Oxetane substituted pyrimidones
KR20130013199A (ko) * 2011-07-27 2013-02-06 한미약품 주식회사 신규 피리미딘 유도체 및 이를 활성성분으로 포함하는 약학 조성물
ES2673183T3 (es) 2011-08-26 2018-06-20 On Light Sciences, Inc. Sistema y método de retirada de tatuajes
EP4076527A4 (en) * 2020-01-10 2024-05-15 Consynance Therapeutics, Inc. COMBINATION DRUG THERAPIES AND THEIR METHODS OF USE
HUP2200222A1 (hu) 2022-06-17 2023-12-28 Richter Gedeon Nyrt MCHR1 antagonisták a Prader-Willi szindróma kezelésére

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0124627D0 (en) * 2001-10-15 2001-12-05 Smithkline Beecham Plc Novel compounds

Also Published As

Publication number Publication date
IL174693A0 (en) 2006-08-20
CO5690599A2 (es) 2006-10-31
MA28111A1 (fr) 2006-08-01
AU2004285913A1 (en) 2005-05-12
CN1871242A (zh) 2006-11-29
MXPA06003997A (es) 2006-07-05
ZA200603181B (en) 2008-01-30
CA2543122A1 (en) 2005-05-12
KR20060100412A (ko) 2006-09-20
JP2007509158A (ja) 2007-04-12
US20070078125A1 (en) 2007-04-05
BRPI0415667A (pt) 2006-12-19
EP1678184A1 (en) 2006-07-12
WO2005042541A1 (en) 2005-05-12

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