NO20061404L - Renseprosess - Google Patents
RenseprosessInfo
- Publication number
- NO20061404L NO20061404L NO20061404A NO20061404A NO20061404L NO 20061404 L NO20061404 L NO 20061404L NO 20061404 A NO20061404 A NO 20061404A NO 20061404 A NO20061404 A NO 20061404A NO 20061404 L NO20061404 L NO 20061404L
- Authority
- NO
- Norway
- Prior art keywords
- acid addition
- free base
- cleaning process
- addition form
- terbinafine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/82—Purification; Separation; Stabilisation; Use of additives
- C07C209/84—Purification
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/27—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/30—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the six-membered aromatic ring being part of a condensed ring system formed by two rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Renseprosess for fremstilling av allylaminlegemiddelet terbinafin med formel (I). På fri baseform eller syreaddisjonsform ved å destillere råterbinafinbase, fortrinnsvis ved kortveisdestillasjon, for eksempel ved en temperatur på over 100 °C og redusert trykk, for eksempel 0,2 mbar, og å utvinne produktet på fri base - eller syreaddisjonsaltform.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0320312.2A GB0320312D0 (en) | 2003-08-29 | 2003-08-29 | Purification process |
PCT/EP2004/009587 WO2005021483A2 (en) | 2003-08-29 | 2004-08-27 | Process for the purification of terbinafine |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20061404L true NO20061404L (no) | 2006-08-25 |
Family
ID=28686596
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20061404A NO20061404L (no) | 2003-08-29 | 2006-03-28 | Renseprosess |
Country Status (25)
Country | Link |
---|---|
US (2) | US20060076227A1 (no) |
EP (1) | EP1694631A2 (no) |
JP (1) | JP5208416B2 (no) |
KR (2) | KR20120054109A (no) |
CN (1) | CN100491334C (no) |
AR (1) | AR045506A1 (no) |
AU (1) | AU2004268051B2 (no) |
BR (1) | BRPI0413896A (no) |
CA (1) | CA2536498C (no) |
EC (1) | ECSP066382A (no) |
GB (1) | GB0320312D0 (no) |
IL (1) | IL173709A (no) |
IS (1) | IS8369A (no) |
MA (1) | MA28030A1 (no) |
MX (1) | MXPA06002348A (no) |
MY (1) | MY149357A (no) |
NO (1) | NO20061404L (no) |
NZ (1) | NZ545445A (no) |
PE (1) | PE20050873A1 (no) |
RU (1) | RU2367649C2 (no) |
SG (1) | SG145782A1 (no) |
TN (1) | TNSN06066A1 (no) |
TW (1) | TWI350829B (no) |
WO (1) | WO2005021483A2 (no) |
ZA (1) | ZA200601264B (no) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0503942D0 (en) * | 2005-02-25 | 2005-04-06 | Novartis Ag | Purification process |
EP1900378A1 (en) * | 2006-08-31 | 2008-03-19 | Novartis AG | Pharmaceutical compositions for the treatment of fungal infections |
JP5514823B2 (ja) | 2008-09-05 | 2014-06-04 | テイコク ファーマ ユーエスエイ、インコーポレーテッド | イオントフォレシス薬物送達パッケージング |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0000896B1 (en) * | 1977-08-19 | 1982-10-13 | Sandoz Ag | Propenyl amines, processes for their production and pharmaceutical compositions containing them |
EP0024587B1 (en) | 1979-08-22 | 1984-11-14 | Sandoz Ag | Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals |
US5132459A (en) * | 1979-08-22 | 1992-07-21 | Sandoz Ltd. | Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals |
CH678527A5 (en) | 1989-06-22 | 1991-09-30 | Sandoz Ag | Trans(E)-N-(1-naphthyl:methyl)-heptenyl-amine prepn. - by simultaneously converting crude mixt. contg. cis and trans isomers to salt and precipitating trans isomer |
JP3116364B2 (ja) * | 1989-10-02 | 2000-12-11 | 萬有製薬株式会社 | エンイン誘導体の製造法 |
NZ280065A (en) * | 1995-09-20 | 1998-04-27 | Apotex Inc | Preparation of n-alkyl-n-(1-naphthylmethyl)alk-2-en-4-ynylamine derivatives |
US6248363B1 (en) | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
RU2217414C1 (ru) | 1999-10-22 | 2003-11-27 | Рихтер Гедеон Ведьесети Дьяр Рт. | Способ получения (e)-n-метил-n-(1-нафтилметил)-6,6-диметилгепт-2-ен-4-инил-1-амина или его кислотно-аддитивной соли |
GB2357762B (en) | 2000-03-13 | 2002-01-30 | Lundbeck & Co As H | Crystalline base of citalopram |
ITMI20010421A1 (it) | 2001-03-01 | 2002-09-02 | Ausimont Spa | Membrane porose semipermeabili di fluoropolimeri semicristallini |
ITMI20010430A1 (it) * | 2001-03-02 | 2002-09-02 | Dinamite Dipharma S P A In For | Metodo per la sintesi di terbinafina |
KR100459275B1 (ko) | 2001-12-28 | 2004-12-03 | 주식회사유한양행 | 터비나핀 또는 그의 염산염의 제조방법 |
ITMI20022534A1 (it) * | 2002-11-29 | 2004-05-30 | Dinamite Dipharma S P A | Procedimento per la preparazione di terbinafina mediante l'uso di platino come catalizzatore. |
US20060004230A1 (en) * | 2004-06-30 | 2006-01-05 | Joseph Kaspi | Process for the preparation of terbinafine and salts thereof |
-
2003
- 2003-08-29 GB GBGB0320312.2A patent/GB0320312D0/en not_active Ceased
-
2004
- 2004-08-26 AR ARP040103068A patent/AR045506A1/es not_active Application Discontinuation
- 2004-08-27 CA CA2536498A patent/CA2536498C/en not_active Expired - Fee Related
- 2004-08-27 TW TW093125943A patent/TWI350829B/zh not_active IP Right Cessation
- 2004-08-27 PE PE2004000823A patent/PE20050873A1/es not_active Application Discontinuation
- 2004-08-27 KR KR1020127012618A patent/KR20120054109A/ko not_active Application Discontinuation
- 2004-08-27 JP JP2006524338A patent/JP5208416B2/ja not_active Expired - Fee Related
- 2004-08-27 BR BRPI0413896-1A patent/BRPI0413896A/pt not_active IP Right Cessation
- 2004-08-27 RU RU2006109640/04A patent/RU2367649C2/ru not_active IP Right Cessation
- 2004-08-27 SG SG200806418-0A patent/SG145782A1/en unknown
- 2004-08-27 CN CNB2004800249663A patent/CN100491334C/zh not_active Expired - Fee Related
- 2004-08-27 AU AU2004268051A patent/AU2004268051B2/en not_active Ceased
- 2004-08-27 NZ NZ545445A patent/NZ545445A/en not_active IP Right Cessation
- 2004-08-27 MX MXPA06002348A patent/MXPA06002348A/es active IP Right Grant
- 2004-08-27 MY MYPI20043511A patent/MY149357A/en unknown
- 2004-08-27 KR KR1020067003979A patent/KR101233024B1/ko not_active IP Right Cessation
- 2004-08-27 WO PCT/EP2004/009587 patent/WO2005021483A2/en active Search and Examination
- 2004-08-27 EP EP04764561A patent/EP1694631A2/en not_active Withdrawn
- 2004-08-27 US US10/522,828 patent/US20060076227A1/en not_active Abandoned
-
2006
- 2006-02-13 ZA ZA200601264A patent/ZA200601264B/en unknown
- 2006-02-13 IL IL173709A patent/IL173709A/en not_active IP Right Cessation
- 2006-02-17 EC EC2006006382A patent/ECSP066382A/es unknown
- 2006-02-27 TN TNP2006000066A patent/TNSN06066A1/en unknown
- 2006-03-08 MA MA28862A patent/MA28030A1/fr unknown
- 2006-03-23 IS IS8369A patent/IS8369A/is unknown
- 2006-03-28 NO NO20061404A patent/NO20061404L/no not_active Application Discontinuation
-
2008
- 2008-11-14 US US12/291,863 patent/US7985323B2/en not_active Expired - Fee Related
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Reestablishment of rights (par. 72 patents act) | ||
FC2A | Withdrawal, rejection or dismissal of laid open patent application |