NO20060134L - Fremgangsmate og anordning for behandling av slitasjegikt, brusklidelse, defekter og skader i det menneskelige kne - Google Patents

Fremgangsmate og anordning for behandling av slitasjegikt, brusklidelse, defekter og skader i det menneskelige kne

Info

Publication number
NO20060134L
NO20060134L NO20060134A NO20060134A NO20060134L NO 20060134 L NO20060134 L NO 20060134L NO 20060134 A NO20060134 A NO 20060134A NO 20060134 A NO20060134 A NO 20060134A NO 20060134 L NO20060134 L NO 20060134L
Authority
NO
Norway
Prior art keywords
knee
tissue
human
morbid
voltage
Prior art date
Application number
NO20060134A
Other languages
English (en)
Inventor
Carl T Brighton
Solomon R Pollack
Original Assignee
Univ Pennsylvania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pennsylvania filed Critical Univ Pennsylvania
Publication of NO20060134L publication Critical patent/NO20060134L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/326Applying electric currents by contact electrodes alternating or intermittent currents for promoting growth of cells, e.g. bone cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0464Specially adapted for promoting tissue growth
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0468Specially adapted for promoting wound healing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/40Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00Magnetotherapy
    • A61N2/02Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N13/00Treatment of microorganisms or enzymes with electrical or wave energy, e.g. magnetism, sonic waves

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Electrotherapy Devices (AREA)
  • Magnetic Treatment Devices (AREA)
  • Prostheses (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

En fremgangsmåte for å bestemme spenning og strøm som kreves for tilføring av spesifikke og selektive elektriske og elektromagnetiske signaler til sykelig leddbrusk ved behandling av slitasjegikt, bruskdefekter på grunn av trauma eller sportsskade eller brukt som et supplement til andre terapier (celletransplantasjon, vevsoppbygning, vekstfaktorer osv.) for behandling av bruskdefekter i det menneskelige kneledd og en anordning for å levere slike signaler til en pasients kne. En analytisk modell av det menneskelig kne er utviklet, hvorved det totale vevvolum i det menneskelige kne kan bestemmes for sammenligning med det totale vevvolum av det sykelige vev i denne animalske modell ved å bruke elektriske felt- og strømtetthetshistogrammer. Spenning og strøm brukt i den animalske modell blir skalert basert på forholdet mellom det totale vevvolum av det sykelige vev i mennesket og det totale vevvolum av det sykelige vev i den animalske modell og det resulterende felt blir tilført det ødelagte vev hos mennesket ved å bruke minst to elektroder tilført i kneet eller en spole eller en solenoid plassert rundt kneet. Spenningen og signalet tilført elektrodene, spolen eller solenoiden varieres basert på størrelsen av kneleddet, idet større kneledd krever større spenninger for å generere det effektive elektriske felt.
NO20060134A 2003-06-09 2006-01-09 Fremgangsmate og anordning for behandling av slitasjegikt, brusklidelse, defekter og skader i det menneskelige kne NO20060134L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/457,167 US7022506B2 (en) 2000-02-23 2003-06-09 Method and device for treating osteoarthritis, cartilage disease, defects and injuries in the human knee
PCT/US2004/018274 WO2004110552A1 (en) 2003-06-09 2004-06-09 Method and device for treating osteoarthritis, cartilage disease, defects and injuries in the human knee

Publications (1)

Publication Number Publication Date
NO20060134L true NO20060134L (no) 2006-03-06

Family

ID=33551305

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20060134A NO20060134L (no) 2003-06-09 2006-01-09 Fremgangsmate og anordning for behandling av slitasjegikt, brusklidelse, defekter og skader i det menneskelige kne

Country Status (15)

Country Link
US (2) US7022506B2 (no)
EP (1) EP1641518A4 (no)
JP (1) JP2007500580A (no)
KR (1) KR100852022B1 (no)
CN (1) CN101076368A (no)
AU (1) AU2004247113A1 (no)
BR (1) BRPI0411840A2 (no)
CA (1) CA2528865C (no)
CR (1) CR8126A (no)
IL (1) IL172472A0 (no)
MX (1) MXPA05013491A (no)
NO (1) NO20060134L (no)
NZ (1) NZ544525A (no)
WO (1) WO2004110552A1 (no)
ZA (1) ZA200600111B (no)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8313908B2 (en) 2000-02-23 2012-11-20 The Trustees Of The University Of Pennsylvania Regulation of stem cell gene production with specific and selective electric and electromagnetic fields
US7022506B2 (en) * 2000-02-23 2006-04-04 The Trustees Of The University Of Pennsylvania Method and device for treating osteoarthritis, cartilage disease, defects and injuries in the human knee
US7429471B2 (en) * 2000-02-23 2008-09-30 The Trustees Of The University Of Pennsylvania Regulation of matrix metalloproteinase gene expression using specific and selective electrical and electromagnetic signals
US7465546B2 (en) * 2000-02-23 2008-12-16 The Trustees Of The University Of Pennsylvania Regulation of transforming growth factor-beta (TGF-β) gene expression in living cells via the application of specific and selective electric and electromagnetic fields
US7981611B2 (en) * 2000-02-23 2011-07-19 The Trustees Of The University Of Pennsylvania Regulation of fibroblastic growth factor-2 (FGF-2) gene expression in living cells with the application of specific and selective electric and electromagnetic fields
US7374916B2 (en) 2000-02-23 2008-05-20 The Trustees Of The University Of Pennsylvania Regulation of aggrecan gene expression using specific and selective electrical and electromagnetic signals
US7465566B2 (en) 2000-02-23 2008-12-16 The Trustees Of The University Of Pennsylvania Regulation of genes via application of specific and selective electrical and electromagnetic signals
US8060210B1 (en) 2002-09-11 2011-11-15 International Rehabilitative Sciences, Inc. Methods for improving mobility and controlling cartilage matrix degradation of weight-bearing articular joints
US8346367B2 (en) 2002-09-11 2013-01-01 Meagan Medical, Inc. Apparatus and method for stabilizing, improving mobility, and controlling cartilage matrix degradation of weight-bearing articular joints
US20070038252A1 (en) * 2005-08-09 2007-02-15 Carroll William J Apparatus for surface electrical stimulation and stabilization to treat disorders of the joints
CN1893999A (zh) * 2003-11-14 2007-01-10 宾夕法尼亚大学理事会 治疗人髋部的骨关节炎与软骨疾病、缺损、与损伤的方法与装置
US20050251229A1 (en) 2004-04-19 2005-11-10 Pilla Arthur A Electromagnetic treatment apparatus and method for angiogensis modulation of living tissues and cells
US20130218235A9 (en) * 2005-03-07 2013-08-22 Arthur A. Pilla Excessive fibrous capsule formation and capsular contracture apparatus and method for using same
US10350428B2 (en) 2014-11-04 2019-07-16 Endonovo Therapetics, Inc. Method and apparatus for electromagnetic treatment of living systems
US7744524B2 (en) * 2003-12-05 2010-06-29 Ivivi Health Sciences, Llc Apparatus and method for electromagnetic treatment of plant, animal, and human tissue, organs, cells, and molecules
US8961385B2 (en) * 2003-12-05 2015-02-24 Ivivi Health Sciences, Llc Devices and method for treatment of degenerative joint diseases with electromagnetic fields
US9440089B2 (en) 2003-12-05 2016-09-13 Rio Grande Neurosciences, Inc. Apparatus and method for electromagnetic treatment of neurological injury or condition caused by a stroke
US9433797B2 (en) 2003-12-05 2016-09-06 Rio Grande Neurosciences, Inc. Apparatus and method for electromagnetic treatment of neurodegenerative conditions
US20110112352A1 (en) * 2003-12-05 2011-05-12 Pilla Arthur A Apparatus and method for electromagnetic treatment
US9415233B2 (en) 2003-12-05 2016-08-16 Rio Grande Neurosciences, Inc. Apparatus and method for electromagnetic treatment of neurological pain
US9656096B2 (en) 2003-12-05 2017-05-23 Rio Grande Neurosciences, Inc. Method and apparatus for electromagnetic enhancement of biochemical signaling pathways for therapeutics and prophylaxis in plants, animals and humans
NZ548447A (en) * 2004-01-12 2010-04-30 Univ Pennsylvania Up-regulation of bone morphogenetic protein (BMP) gene expression in bone cells by electromagnetic signals
US8454543B2 (en) 2004-03-10 2013-06-04 Vision Quest Industries Incorporated Electrodes for orthotic device
US8070703B2 (en) * 2004-03-10 2011-12-06 Vision Quest Industries Incorporated Electrically stimulating orthotic device and segmented liner
US8936560B2 (en) * 2004-03-10 2015-01-20 Vision Quest Industries Incorporated Bracing and electrostimulation for arthritis
US7473678B2 (en) * 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
WO2006116354A1 (en) * 2005-04-21 2006-11-02 Ksm, Inc. Electromagnetic treatment device
US7840272B2 (en) 2005-06-03 2010-11-23 Medrelief Inc. Methods for modulating osteochondral development using bioelectrical stimulation
US20070039211A1 (en) * 2005-08-17 2007-02-22 Thomas Pichler Orthotic insert having recess for therapeutic patch
WO2007061889A2 (en) * 2005-11-17 2007-05-31 Biomimetic Therapeutics, Inc. Maxillofacial bone augmentation using rhpdgf-bb and a biocompatible matrix
WO2007092622A2 (en) * 2006-02-09 2007-08-16 Biomimetic Therapeutics, Inc. Compositions and methods for treating bone
JP2007322191A (ja) * 2006-05-31 2007-12-13 Oki Electric Ind Co Ltd 半導体加速度センサ
EP2049145B1 (en) 2006-06-30 2018-03-14 BioMimetic Therapeutics, LLC Pdgf-biomatrix compositions and methods for treating rotator cuff injuries
US9161967B2 (en) * 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
EP3181157B1 (en) 2006-11-03 2019-08-14 BioMimetic Therapeutics, LLC Compositions and methods for arthrodetic procedures
US20080172106A1 (en) * 2007-01-11 2008-07-17 Mcginnis William J Osteogenic stimulus device, kit and method of using thereof
US20080171304A1 (en) * 2007-01-11 2008-07-17 Mcginnis William J Dental implant kit and method of using same
US20080172107A1 (en) * 2007-01-11 2008-07-17 Mcginnis William J Stand alone osteogenic stimulus device and method of using
US8423148B1 (en) * 2007-03-19 2013-04-16 Michael Lytinas Method for treating cartilage defects
US9968797B2 (en) 2007-05-03 2018-05-15 Orthocor Medical, Inc. Electromagnetic thermal therapy
US7783348B2 (en) * 2007-05-03 2010-08-24 Orthocor Medical, Inc. Stimulation device for treating osteoarthritis
US8768454B2 (en) * 2007-05-03 2014-07-01 Orthocor Medical, Inc. Electromagnetic thermal therapy
RU2010137106A (ru) 2008-02-07 2012-03-20 Байомайметик Терапьютикс, Инк. (Us) Композиции и способы для дистракциионного остеогенеза
CN101559254A (zh) * 2008-04-15 2009-10-21 万芪 治疗脑损伤的方法、装置及其用途
CN102231992B (zh) * 2008-09-09 2015-05-20 生物模拟治疗公司 用于治疗肌腱和韧带损伤的血小板衍生生长因子的组合物和方法
WO2010102266A1 (en) * 2009-03-05 2010-09-10 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods for the treatment of osteochondral defects
US8460167B2 (en) * 2009-09-14 2013-06-11 Minnesota Medical Physics Llc Thermally assisted pulsed electro-magnetic field stimulation device and method for treatment of osteoarthritis
US8932196B2 (en) 2009-09-14 2015-01-13 Minnesota Medical Physics Llc Thermally assisted pulsed electro-magnetic field stimulation device and method for treatment of osteoarthritis
US8827886B2 (en) 2009-09-14 2014-09-09 Minnesota Medical Physics Llc Thermally assisted pulsed electro-magnetic field stimulation device and method for treatment of osteoarthritis
CN107080834A (zh) 2010-02-22 2017-08-22 生物模拟治疗有限责任公司 用于治疗腱病的血小板衍生生长因子组合物和方法
CA2813036A1 (en) 2010-10-01 2012-04-05 Ivivi Health Sciences, Llc Method and apparatus for electromagnetic treatment of head, cerebral and neural injury in animals and humans
US8972019B2 (en) 2011-01-25 2015-03-03 Kenneth L. Willeford Method and device for treating osteoarthritis noninvasively
WO2013016664A2 (en) 2011-07-27 2013-01-31 Vision Quest Industries Incorporated Dba Vq Orthocare Electrostimulation system
US8343027B1 (en) 2012-01-30 2013-01-01 Ivivi Health Sciences, Llc Methods and devices for providing electromagnetic treatment in the presence of a metal-containing implant
WO2014191991A1 (en) * 2013-05-26 2014-12-04 Ramot At Tel-Aviv University Ltd. Diagnostic and monitoring electrical impedance tomography (eit) system for osteoporosis
WO2015161063A1 (en) 2014-04-16 2015-10-22 Iviv Health Sciences, Llc A two-part pulsed electromagnetic field applicator for application of therapeutic energy
KR101675414B1 (ko) * 2014-11-17 2016-11-11 경상대학교산학협력단 뼈 재생장치
RU2609998C1 (ru) * 2015-10-19 2017-02-07 Борис Николаевич Анисимов Способ КВЧ-фореза в реабилитации лиц с дегенеративно-дистрофическими изменениями опорно-двигательного аппарата на курортном этапе
KR101694392B1 (ko) * 2016-06-02 2017-01-10 단국대학교 천안캠퍼스 산학협력단 통증 제어를 위한 전류 제어 기반 전기기계적 연골 성형 장치
US10806942B2 (en) 2016-11-10 2020-10-20 Qoravita LLC System and method for applying a low frequency magnetic field to biological tissues
CN106581861A (zh) * 2016-12-15 2017-04-26 四川大学 治疗膝骨关节炎及软骨损伤的低频脉冲电磁仪及系统
RU2685637C1 (ru) * 2018-06-07 2019-04-22 Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования "Российская медицинская академия непрерывного профессионального образования" Министерства здравоохранения Российской Федерации (ФГБОУ ДПО РМАНПО Минздрава России) Способ лечения и реабилитации пациентов с остеоартрозом коленного сустава и сопутствующей варикозной болезнью вен нижних конечностей
KR102211688B1 (ko) 2018-11-30 2021-02-02 서울여자대학교 산학협력단 무릎 자기공명 영상에서의 반월상 연골 분할 방법 및 장치
CN113454913A (zh) * 2018-12-06 2021-09-28 路易斯安娜州立大学监测委员会,农业和机械学院 使用磁芯施加具有高均匀性的脉冲电场的方法和系统
US11869151B2 (en) * 2021-01-26 2024-01-09 Beth Israel Deaconess Medical Center Systems and methods for finite element analysis of tumor treating fields
KR20230031796A (ko) 2021-08-27 2023-03-07 연세대학교 원주산학협력단 전기자극을 이용하여 손상된 관절 연골 재생 장치 및 그 방법

Family Cites Families (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4506674A (en) 1981-11-10 1985-03-26 Trustees Of The University Of Pennsylvania Method of stimulating osteogenesis with distributed port cathode
US4442846A (en) 1981-11-10 1984-04-17 University Of Pennsylvania Distributed port bone-piercing cathode for electrically stimulated osteogenesis
US4430999A (en) 1981-11-10 1984-02-14 Trustees Of The University Of Pennsylvania Osteogenesis stimulating cathode assembly for use with an internal fixation device
US4509520A (en) 1982-02-22 1985-04-09 Biolectron, Inc. Electrical stimulating apparatus
US4549547A (en) 1982-07-27 1985-10-29 Trustees Of The University Of Pennsylvania Implantable bone growth stimulator
US4467809A (en) * 1982-09-17 1984-08-28 Biolectron, Inc. Method for non-invasive electrical stimulation of epiphyseal plate growth
US4467808A (en) 1982-09-17 1984-08-28 Biolectron, Inc. Method for preventing and treating osteoporosis in a living body by using electrical stimulation non-invasively
US4487834A (en) 1982-09-17 1984-12-11 Biolectron, Inc. Electrical stimulation of articular chondrocytes
US5269746A (en) 1982-12-20 1993-12-14 Jacobson Jerry I Therapeutic treatment of mammals for epilepsy and Parkinson's disease
US4535775A (en) 1983-02-10 1985-08-20 Biolectron, Inc. Method for treatment of non-union bone fractures by non-invasive electrical stimulation
IT1159024B (it) 1983-06-02 1987-02-25 Ruggero Cadossi Metodo e dispositivo per il trattamento di tessuti e cellule viventi mediante campi elettromagnetici pulsanti
JPH0742219B2 (ja) * 1984-07-26 1995-05-10 ライオン株式会社 口腔用組成物
US4600010A (en) 1984-10-04 1986-07-15 Biolectron, Inc. Electric stimulator and test instrument therefor
US4998532A (en) * 1986-05-23 1991-03-12 Lti Biomedical, Inc. Portable electro-therapy system
US5014699A (en) 1986-05-23 1991-05-14 Trustees Of The University Of Pennsylvania Electromagnetic method and apparatus for healing living tissue
US5015464A (en) * 1987-03-25 1991-05-14 Amway Corporation Antiplaque chewing gum
US6120502A (en) * 1988-06-13 2000-09-19 Michelson; Gary Karlin Apparatus and method for the delivery of electrical current for interbody spinal arthrodesis
CA2004192A1 (en) * 1988-11-30 1990-05-31 Jerry I. Jacobson Therapeutic treatment of mammals
US5038797A (en) 1990-02-20 1991-08-13 Romaine, Incorporated Electrical stimulation treatment device and method of use
MY106919A (en) * 1990-08-31 1995-08-30 Kao Corp Composition for use in oral cavity.
US5273033A (en) 1991-09-19 1993-12-28 Murray Electronics Associates Limited Partnership Electrical stimulation for treatment of osteoarthritis
USPP8645P (en) * 1992-10-27 1994-03-15 Aromatics, Inc. Low menthol mint plant Mentha spicata L. `Erospicata`
US5338286A (en) 1992-12-08 1994-08-16 Electro-Biology, Inc. Electromagnetic bioresponse by selective spectral suppression in pulsed field stimulation
US5372824A (en) * 1993-03-25 1994-12-13 The Wm. Wrigley Jr. Company Mint flavored chewing gum having reduced bitterness and methods for making same
US5374283A (en) 1993-12-01 1994-12-20 Flick; A. Bart Electrical therapeutic apparatus
AU2209195A (en) * 1994-04-12 1995-10-30 Australasian Medical Technology (Nz) Limited Orthotic devices incorporating pulsed electromagnetic field therapy
US6132362A (en) 1996-11-01 2000-10-17 Amei Technologies, Inc. Pulsed electromagnetic field (PEMF) stimulation therapy system with bi-phasic coil
US5743844A (en) 1996-11-01 1998-04-28 Amei Technologies, Inc. High efficiency pulsed electromagnetic field (PEMF) stimulation therapy method and system
US6261221B1 (en) 1996-11-01 2001-07-17 Amei Technologies Inc. Flexible coil pulsed electromagnetic field (PEMF) stimulation therapy system
US5968527A (en) 1997-02-27 1999-10-19 Catholic University Of America, The Protection of living systems from the adverse effects of stress
US6083149A (en) 1997-10-22 2000-07-04 Emf Therapeutics, Inc. Magnetic field device and method for inhibiting angiogenesis and retarding growth rates of tumors in mammals
US6186940B1 (en) 1998-05-18 2001-02-13 Robert N. Kirschbaum Energized trace elements
US6292699B1 (en) 1999-01-29 2001-09-18 Electro-Biology, Inc. Direct current stimulation of spinal interbody fixation device
US6747004B1 (en) * 1999-04-29 2004-06-08 North Shore - Long Island Jewish Research Institute Method for inducing growth and enhancing survival of nervous tissue
DE19933719A1 (de) 1999-07-19 2001-01-25 Medigene Ag Strukturprotein in Adeno-assoziiertem Virus mit veränderten chromatographischen Eigenschaften, seine Herstellung und Verwendung
MXPA02006658A (es) * 2000-01-07 2004-09-10 Biowave Corp Metodo y aparato de electroterapia.
US7429471B2 (en) * 2000-02-23 2008-09-30 The Trustees Of The University Of Pennsylvania Regulation of matrix metalloproteinase gene expression using specific and selective electrical and electromagnetic signals
US6919205B2 (en) * 2000-02-23 2005-07-19 The Trustees Of The University Of Pennsylvania Regulation of type II collagen gene expression using specific and selective electrical and electromagnetic signals
US7465546B2 (en) * 2000-02-23 2008-12-16 The Trustees Of The University Of Pennsylvania Regulation of transforming growth factor-beta (TGF-β) gene expression in living cells via the application of specific and selective electric and electromagnetic fields
US7465566B2 (en) 2000-02-23 2008-12-16 The Trustees Of The University Of Pennsylvania Regulation of genes via application of specific and selective electrical and electromagnetic signals
US7130692B2 (en) * 2000-02-23 2006-10-31 The Trustees Of The University Of Pennsylvania Portable electrotherapy device for treating osteoarthritis and other diseases, defects and injuries of the knee joint
US7022506B2 (en) 2000-02-23 2006-04-04 The Trustees Of The University Of Pennsylvania Method and device for treating osteoarthritis, cartilage disease, defects and injuries in the human knee
US6485963B1 (en) * 2000-06-02 2002-11-26 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Growth stimulation of biological cells and tissue by electromagnetic fields and uses thereof
US20020052634A1 (en) 2000-11-02 2002-05-02 March Keith L. Method and system for modulation of oscillating signals to enhance biologic effects
US6485113B2 (en) * 2001-03-08 2002-11-26 Delphi Technologies, Inc. Haptic braking method and system
US7167753B2 (en) * 2001-07-03 2007-01-23 The Trustees Of The University Of Pennsylvania Device and method for electrically inducing osteogenesis in the spine
EP1465703A4 (en) * 2001-12-21 2007-05-23 Univ Pennsylvania DEVICE FOR PREVENTING AND / OR TREATING OSTEOPOROSIS, VERTEBRAL AND HIP FRACTURES AND / OR VERTEBRAL FUSIONS USING ELECTRIC FIELDS
US6955642B1 (en) * 2002-11-26 2005-10-18 Ebi, Lp Pulsed electromagnetic field stimulation method and apparatus with improved dosing
US6929699B2 (en) * 2002-12-13 2005-08-16 Texas Instruments Incorporated Gas injectors for a vertical furnace used in semiconductor processing
CN1893999A (zh) * 2003-11-14 2007-01-10 宾夕法尼亚大学理事会 治疗人髋部的骨关节炎与软骨疾病、缺损、与损伤的方法与装置
NZ548447A (en) 2004-01-12 2010-04-30 Univ Pennsylvania Up-regulation of bone morphogenetic protein (BMP) gene expression in bone cells by electromagnetic signals

Also Published As

Publication number Publication date
EP1641518A4 (en) 2008-11-19
JP2007500580A (ja) 2007-01-18
CR8126A (es) 2006-07-11
KR20060021366A (ko) 2006-03-07
ZA200600111B (en) 2007-02-28
CN101076368A (zh) 2007-11-21
KR100852022B1 (ko) 2008-08-13
US20040006373A1 (en) 2004-01-08
NZ544525A (en) 2008-01-31
BRPI0411840A2 (pt) 2015-07-14
CA2528865C (en) 2011-09-13
AU2004247113A1 (en) 2004-12-23
US7022506B2 (en) 2006-04-04
IL172472A0 (en) 2006-04-10
WO2004110552A1 (en) 2004-12-23
US7468264B2 (en) 2008-12-23
MXPA05013491A (es) 2006-05-19
US20060190043A1 (en) 2006-08-24
CA2528865A1 (en) 2004-12-23
EP1641518A1 (en) 2006-04-05

Similar Documents

Publication Publication Date Title
NO20060134L (no) Fremgangsmate og anordning for behandling av slitasjegikt, brusklidelse, defekter og skader i det menneskelige kne
JP4455801B2 (ja) 特異的且つ選択的な電気的及び電磁気的シグナルの施用による遺伝子の調節
KR101324824B1 (ko) 특이적이고 선택적인 전기 신호 및 전자기 신호에 의해생성된 장의 적용을 통해 골 세포에서의 골 형태형성단백질 (bmp) 유전자 발현을 상향-조절하는 시스템 및방법
US20070060981A1 (en) Integrated coil apparatus for therapeutically treating human and animal cells, tissues and organs with electromagnetic fields and method for using same
WO2004009175A3 (en) Method for treating tissue with a wet electrode and apparatus for using same
ATE501681T1 (de) Vorrichtung zur elektrothermischen behandlung des menschlichen oder tierischen körpers
BRPI0411817A (pt) aparelho e método para estimulação bioelétrica, aceleração da cura, alìvio da dor ou desvitalização de patógenos
NO20060414L (no) Baerbar elektroterapianordning for kneledd-sykdommer
US6497648B1 (en) Device for applying electromagnetic therapy
CA2545860A1 (en) Device for treating osteoarthritis and cartilage disease, defects, and injuries in the human hip
FI921913A0 (fi) Apparat och foerfarande foer genom kraniet utfoerd elektroterapi.
JP2009524480A (ja) 独立型の電磁気によるセレブロフェイシャル領域の治療装置及びこれを利用する方法
Morris et al. Gracilis muscle: arterial and neural basis for subdivision
RU2010137343A (ru) Регуляция экспрессии фактора роста фибробластов-2 (fgf -2) в живых клетках с помощью применения специфических и избирательных электрических и электромагнитных полей
Martini et al. Shock wave therapy as an innovative technology in skeletal disorders: study on transmembrane current in stimulated osteoblast-like cells
GRANBERRY et al. The lack of effect of microwave diathermy on rate of growth of bone of the growing dog
CN203539903U (zh) 一种抑制关节置换术后假体周围骨溶解的超声仪
CN206365951U (zh) 一种用于小鼠骨髓微环境损伤模型建立的电击装置
Khoo et al. Vascularized Denervated Muscle Targets: A Comparison with Regenerative Peripheral Nerve Interfaces to Determine Association Between Muscle Graft Size and Pain
Molaei et al. Experimental reconstruction of teat mucosa by vestibular mucosal graft in cows. A histopathologic and radiographic study
Furue et al. In vivo and in vitro patch-clamp analyses of excitatory and inhibitory synaptic responses in substantia gelatinosa neurons of the rat spinal dorsal horn
Vaz Direct Stimulation for Ligament Regeneration
Schenkman et al. Gastropyeloplasty: a swine model
KR820001427B1 (ko) 치료장치
Martinek et al. Ex-vivo gene transfer for preconditioning of ACL tendon grafts

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application