NO20053271L - 8-trialkylsiloksy-2,3-dimetyl-9-fenyl-7-okso-7,8,9,10-tetrahydro-imidazo[1,2h]naftyridiner - Google Patents

8-trialkylsiloksy-2,3-dimetyl-9-fenyl-7-okso-7,8,9,10-tetrahydro-imidazo[1,2h]naftyridiner

Info

Publication number
NO20053271L
NO20053271L NO20053271A NO20053271A NO20053271L NO 20053271 L NO20053271 L NO 20053271L NO 20053271 A NO20053271 A NO 20053271A NO 20053271 A NO20053271 A NO 20053271A NO 20053271 L NO20053271 L NO 20053271L
Authority
NO
Norway
Prior art keywords
trialkylsiloxy
naphthyridines
imidazo
tetrahydro
oxo
Prior art date
Application number
NO20053271A
Other languages
English (en)
Inventor
Bernhard Kohl
Jorg Senn-Bilfinger
Jan Koek
Tone Vries
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Publication of NO20053271L publication Critical patent/NO20053271L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Forbindelser med formel 1 og. deres salter er verdifulle. intermediater for å fremstille. aktive forbindelser for. forebyggingen og behandlingen. av gastrointestinale sykdommer.Forbindelser med formel 1, hvor R1 er hydrogen, metyl eller hydroksymetyl, R2a og R2b er begge hydrogen eller angir sammen en binding, R3 er 1-7C -alkyl, R4 er 1-7C-alkyl og R5 er 1-7C -alkyl, og deres salter, er verdifulle intermediater for å fremstille aktive forbindelser for å fremstille aktive forbindelser for forebyggingen og behandlingen av gastrointestinale sykdommer.
NO20053271A 2002-12-20 2005-07-04 8-trialkylsiloksy-2,3-dimetyl-9-fenyl-7-okso-7,8,9,10-tetrahydro-imidazo[1,2h]naftyridiner NO20053271L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02028672 2002-12-20
PCT/EP2003/014554 WO2004056362A2 (en) 2002-12-20 2003-12-18 8-trialkysyloxy-2-methyl-9-phenyl-7-0 xo-7,8,9,10- tetrahydroimidazo ‘1,2-h! ‘1,7! naphthyridines

Publications (1)

Publication Number Publication Date
NO20053271L true NO20053271L (no) 2005-07-04

Family

ID=32668731

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20053271A NO20053271L (no) 2002-12-20 2005-07-04 8-trialkylsiloksy-2,3-dimetyl-9-fenyl-7-okso-7,8,9,10-tetrahydro-imidazo[1,2h]naftyridiner

Country Status (16)

Country Link
US (1) US20060041134A1 (no)
EP (1) EP1585516A2 (no)
JP (1) JP2006515848A (no)
KR (1) KR20050088176A (no)
CN (1) CN1726031A (no)
AU (1) AU2003293940A1 (no)
BR (1) BR0316752A (no)
CA (1) CA2509882A1 (no)
EA (1) EA010107B1 (no)
HR (1) HRP20050632A2 (no)
MX (1) MXPA05006349A (no)
NO (1) NO20053271L (no)
PL (1) PL375933A1 (no)
RS (1) RS20050449A (no)
WO (1) WO2004056362A2 (no)
ZA (1) ZA200504045B (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1831150A1 (en) * 2004-07-23 2007-09-12 DSMIP Assets B.V. Process for the preparation of (2r, 3r)-2-hydroxy-3-amino-3-aryl-propionamide and (2r, 3r)-2-hydroxy-3-amino-3-aryl-propionic acid alkyl ester

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998042707A1 (en) * 1997-03-24 1998-10-01 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyrido compounds
CZ292335B6 (cs) * 1998-09-23 2003-09-17 Altana Pharma Ag Tetrahydropyridoethery, jejich použití a farmaceutický prostředek
CA2404460A1 (en) * 2000-03-29 2001-10-04 Altana Pharma Ag Alkylated imidazopyridine derivatives
ATE328883T1 (de) * 2000-03-29 2006-06-15 Altana Pharma Ag Imidazopyridin-8-one
MXPA02009551A (es) * 2000-03-29 2004-05-14 Altana Pharma Ag Profarmacos de derivados de imidazopiridina.
CA2404477A1 (en) * 2000-03-29 2001-10-04 Altana Pharma Ag Tricyclic imidazopyridines
CN1692113A (zh) * 2000-10-25 2005-11-02 奥坦纳医药公司 作为胃分泌抑制剂的多取代咪唑并吡啶
TWI295575B (en) * 2002-04-24 2008-04-11 Altana Pharma Ag Nitrosated imidazopyridines

Also Published As

Publication number Publication date
MXPA05006349A (es) 2005-08-26
BR0316752A (pt) 2005-10-25
WO2004056362A3 (en) 2004-09-02
CA2509882A1 (en) 2004-07-08
AU2003293940A1 (en) 2004-07-14
CN1726031A (zh) 2006-01-25
PL375933A1 (en) 2005-12-12
HRP20050632A2 (hr) 2006-04-30
JP2006515848A (ja) 2006-06-08
US20060041134A1 (en) 2006-02-23
EP1585516A2 (en) 2005-10-19
EA010107B1 (ru) 2008-06-30
KR20050088176A (ko) 2005-09-02
EA200500903A1 (ru) 2005-12-29
WO2004056362A2 (en) 2004-07-08
RS20050449A (en) 2007-11-15
ZA200504045B (en) 2006-07-26

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Legal Events

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Representative=s name: PLOUGMANN & VINGTOFT, POSTBOKS 1003 SENTRUM, 0104

FC2A Withdrawal, rejection or dismissal of laid open patent application