NO20050338L - Nukleotidsekvenser som koder for torsingener torsinproteiner og fremgangsmater for anvendelse av det samme for behandling av proteinaggregering - Google Patents

Nukleotidsekvenser som koder for torsingener torsinproteiner og fremgangsmater for anvendelse av det samme for behandling av proteinaggregering

Info

Publication number
NO20050338L
NO20050338L NO20050338A NO20050338A NO20050338L NO 20050338 L NO20050338 L NO 20050338L NO 20050338 A NO20050338 A NO 20050338A NO 20050338 A NO20050338 A NO 20050338A NO 20050338 L NO20050338 L NO 20050338L
Authority
NO
Norway
Prior art keywords
methods
tor
torsin
protein aggregation
genes
Prior art date
Application number
NO20050338A
Other languages
English (en)
Norwegian (no)
Inventor
Guy A Caldwell
Kim A Caldwell
Original Assignee
Univ Alabama
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Alabama filed Critical Univ Alabama
Publication of NO20050338L publication Critical patent/NO20050338L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/04Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Neurology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Psychology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
NO20050338A 2002-06-24 2005-01-21 Nukleotidsekvenser som koder for torsingener torsinproteiner og fremgangsmater for anvendelse av det samme for behandling av proteinaggregering NO20050338L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/177,104 US20030235823A1 (en) 2002-06-24 2002-06-24 Nucleotide sequences that code for torsin genes, torsin proteins, and methods of using the same to treat protein-aggregation
PCT/US2003/016229 WO2004000996A2 (en) 2002-06-24 2003-06-24 Nucleotide sequences that code for torsin genes, torsin proteins, and methods of using the same to treat protein-aggregation

Publications (1)

Publication Number Publication Date
NO20050338L true NO20050338L (no) 2005-02-21

Family

ID=29734294

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20050338A NO20050338L (no) 2002-06-24 2005-01-21 Nukleotidsekvenser som koder for torsingener torsinproteiner og fremgangsmater for anvendelse av det samme for behandling av proteinaggregering

Country Status (7)

Country Link
US (3) US20030235823A1 (de)
EP (1) EP1572951A2 (de)
JP (1) JP2006517383A (de)
AU (1) AU2003243299A1 (de)
CA (1) CA2490746A1 (de)
NO (1) NO20050338L (de)
WO (1) WO2004000996A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002059297A2 (en) * 2001-01-25 2002-08-01 Evolva Biotech A/S A library of a collection of cells
US8008459B2 (en) * 2001-01-25 2011-08-30 Evolva Sa Concatemers of differentially expressed multiple genes
JP4472345B2 (ja) * 2002-01-25 2010-06-02 エヴォルヴァ・リミテッド 複数パラメータースクリーニングおよび複数機能性小分子産生細胞への進化方法
WO2004016791A1 (en) * 2002-08-01 2004-02-26 Evolva Ltd Methods of mixing large numbers of heterologous genes
KR20050053607A (ko) * 2002-08-07 2005-06-08 유니버시티 오브 델라웨어 단백질 오조립 및 응집을 나타내는 질병을 치료하기 위한조성물 및 방법
KR20050101554A (ko) 2003-02-14 2005-10-24 바이오겐 아이덱 엠에이 인코포레이티드 외인성 분자를 일시적으로 또는 안정하게 발현하기 위한발현 카세트 및 발현 벡터
ES2307018T3 (es) * 2003-07-11 2008-11-16 Remynd Nv Modelo de levadura para la toxicidad de proteinas amiloidogenicas.
AU2006216442A1 (en) * 2005-02-25 2006-08-31 The Board Of Trustees Of The University Of Alabama For And On Behalf Of The University Of Alabama Regulators of protein misfolding and aggregation and methods of using the same
US20070212333A1 (en) * 2005-10-11 2007-09-13 University Of Illinois Urbana Methods and compositions for the treatment of dystonia
US20100129796A1 (en) * 2008-11-24 2010-05-27 Micah Halpern Dye probe fluorescence resonance energy transfer genotyping

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6921814B2 (en) * 1997-06-19 2005-07-26 The General Hospital Corporation Torsin, torsin-related genes and methods of detecting neuronal disease
EP0989995A2 (de) * 1997-06-19 2000-04-05 The General Hospital Corporation Torsin, dafür kodierende gene, und deren verwendungen

Also Published As

Publication number Publication date
US20030235823A1 (en) 2003-12-25
JP2006517383A (ja) 2006-07-27
US20050227279A1 (en) 2005-10-13
AU2003243299A1 (en) 2004-01-06
EP1572951A2 (de) 2005-09-14
US20060068472A1 (en) 2006-03-30
CA2490746A1 (en) 2003-12-31
WO2004000996A2 (en) 2003-12-31

Similar Documents

Publication Publication Date Title
NO20050338L (no) Nukleotidsekvenser som koder for torsingener torsinproteiner og fremgangsmater for anvendelse av det samme for behandling av proteinaggregering
ATE510011T1 (de) Neue pilzproteine und diese codierende nukleinsäuren
DE60232870D1 (de) Neue polynukleotide und polypeptide des erythropoietingens
DE60227361D1 (de) Computer vermitteltes assembly von polynucleotiden kodierend für ein zielgerichtetes polypeptide
ATE441711T1 (de) Peptide fähig die dimerisierung von c-jun zu inhibieren
WO2006128668A3 (en) Coagulation factor x polypeptides with modified activation properties
ATE513917T1 (de) Bakterielle expression von proteaseinhibitoren und varianten davon
HUP0301356A2 (hu) Új, DPPIV-gyel rokon szerin proteáz gének
SG142154A1 (en) Methods for genomic analysis
DK1781782T3 (da) Modificerede vitamin K-afhængige polypeptider
DE60335794D1 (de) Multigene vectoren und methoden für eine erhöhte expression von rekombinanten polypeptiden
DK0858467T3 (da) Materialer og fremgangsmåder angående identifikationen og sekventeringen af BRCA2 cancerfölsomhedsgen og anvendelser deraf
WO2002044320A3 (en) Human elongase genes and uses thereof
NO20034692D0 (no) Nye polynukleotider og polypeptider av IFN gamma-17 genet
Inoue et al. Molecular cloning and sequencing of the banded dogfish (Triakis scyllia) interleukin-8 cDNA
RS92704A (en) Immunoglobulin-domain containing cell surface recognition molecules
Trotta et al. Modelling of the membrane receptor CXCR3 and its complexes with CXCL9, CXCL10 and CXCL11 chemokines: putative target for new drug design
NO20055210D0 (no) Inhibitorproteiner av en protease og anvendelse derav
Demina et al. Comparative analysis of complete genome sequences of European subtype tick-borne encephalitis virus strains isolated from Ixodes persulcatus ticks, long-tailed ground squirrel (Spermophilus undulatus), and human blood in the Asian part of Russia
ATE464320T1 (de) Ntb-a, ein oberflächenmolekül impliziert in der aktivität natürlicher killerzellen (nk)
WO2004042083A3 (en) Nucleic acid ligands and uses therefor
ATE488592T1 (de) Auf antibiotikum basierendes genregulationssystem
WO2002095067A3 (en) INTERFERON α-14 POLYMORPHISM
FI943146A0 (fi) Signaalipeptideistä vapaiden stafylokinaasien ilmentyminen
Kuehnel et al. Foot-and-mouth disease virus leader proteinase: specificity at the P2 and P3 positions and comparison with other papain-like enzymes

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application