NO20035137D0 - Fremgangsmåte til isolering av krystallinsk imipenem - Google Patents

Fremgangsmåte til isolering av krystallinsk imipenem

Info

Publication number
NO20035137D0
NO20035137D0 NO20035137A NO20035137A NO20035137D0 NO 20035137 D0 NO20035137 D0 NO 20035137D0 NO 20035137 A NO20035137 A NO 20035137A NO 20035137 A NO20035137 A NO 20035137A NO 20035137 D0 NO20035137 D0 NO 20035137D0
Authority
NO
Norway
Prior art keywords
isolating crystalline
crystalline imipenem
imipenem
isolating
crystalline
Prior art date
Application number
NO20035137A
Other languages
English (en)
Inventor
Yatendra Kumar
Neera Tewari
Bishwa Prakash Rai
Ram Chander Aryan
Original Assignee
Ranbaxy Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd
Publication of NO20035137D0 publication Critical patent/NO20035137D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/02—Preparation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
NO20035137A 2001-05-18 2003-11-18 Fremgangsmåte til isolering av krystallinsk imipenem NO20035137D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN595DE2001 2001-05-18
PCT/IB2002/001718 WO2002094773A2 (en) 2001-05-18 2002-05-20 Process for the isolation of crystalline imipenem

Publications (1)

Publication Number Publication Date
NO20035137D0 true NO20035137D0 (no) 2003-11-18

Family

ID=11097062

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20035137A NO20035137D0 (no) 2001-05-18 2003-11-18 Fremgangsmåte til isolering av krystallinsk imipenem

Country Status (17)

Country Link
US (1) US7241885B2 (no)
EP (1) EP1395588A4 (no)
JP (1) JP2005514323A (no)
KR (1) KR20040010649A (no)
CN (1) CN1522255A (no)
AR (1) AR036018A1 (no)
BR (1) BR0209844A (no)
CA (1) CA2447673A1 (no)
CZ (1) CZ20033351A3 (no)
HU (1) HUP0501093A2 (no)
MX (1) MXPA03010548A (no)
NO (1) NO20035137D0 (no)
OA (1) OA12608A (no)
PL (1) PL373527A1 (no)
SK (1) SK15092003A3 (no)
WO (1) WO2002094773A2 (no)
ZA (1) ZA200309288B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL370705A1 (en) * 2001-05-18 2005-05-30 Ranbaxy Laboratories Limited Process for the preparation of imipenem
WO2003016312A1 (fr) * 2001-08-13 2003-02-27 Eisai Co., Ltd. Procede de preparation d'antibiotiques a base de carbapenem
EP1448563A1 (en) * 2001-11-16 2004-08-25 Ranbaxy Laboratories, Ltd. Process for the preparation of crystalline imipenem
EP2209787A4 (en) * 2007-10-08 2011-08-03 Orchid Chemicals & Pharm Ltd METHOD FOR PRODUCING A CARBAPENEM ANTIBIOTICS
CN103524508B (zh) * 2013-09-02 2016-03-30 上海龙翔生物医药开发有限公司 一种亚胺培南一水合物的结晶方法
CN108623598A (zh) * 2018-05-21 2018-10-09 重庆天地药业有限责任公司 一种亚胺培南中间体及亚胺培南的制备方法
CN113135916A (zh) * 2020-01-20 2021-07-20 鲁南制药集团股份有限公司 一种亚胺培南制备工艺的除钯方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4138433A (en) * 1975-06-26 1979-02-06 Hoechst Aktiengesellschaft Process for preparing 1,2-oxa-phospholanes
US4194047A (en) * 1975-11-21 1980-03-18 Merck & Co., Inc. Substituted N-methylene derivatives of thienamycin
US4081455A (en) * 1976-06-02 1978-03-28 Pfizer Inc. 6-Amino-2,2-dimethyl-3-cyanopenams
US4260543A (en) * 1978-07-03 1981-04-07 Merck & Co., Inc. Crystalline N-formimidoyl thienamycin
US4292436A (en) * 1980-06-25 1981-09-29 Merck & Co., Inc. Process for the preparation of N-protected N-formimidoyl 2-aminoethanethiol
US4374772A (en) * 1981-03-19 1983-02-22 Merck & Co., Inc. Process for the preparation of N-formimidoyl thienamycin and reagents therefor
US4894450A (en) * 1987-05-11 1990-01-16 Merck & Co., Inc. Process for 2-(aminoalkylthio) carbapenems
US5245069A (en) * 1992-10-27 1993-09-14 Merck & Co., Inc. Process for the preparation of bis(aryl)-phosphorohalidates
IN191798B (no) * 2000-11-03 2004-01-03 Ranbaxy Lab Ltd
EP1448563A1 (en) * 2001-11-16 2004-08-25 Ranbaxy Laboratories, Ltd. Process for the preparation of crystalline imipenem

Also Published As

Publication number Publication date
AR036018A1 (es) 2004-08-04
WO2002094773A3 (en) 2003-10-16
BR0209844A (pt) 2005-04-05
HUP0501093A2 (en) 2006-03-28
CN1522255A (zh) 2004-08-18
KR20040010649A (ko) 2004-01-31
MXPA03010548A (es) 2004-05-27
PL373527A1 (en) 2005-09-05
US20040242865A1 (en) 2004-12-02
EP1395588A2 (en) 2004-03-10
WO2002094773A2 (en) 2002-11-28
OA12608A (en) 2006-06-08
SK15092003A3 (sk) 2004-09-08
CZ20033351A3 (cs) 2007-12-27
EP1395588A4 (en) 2004-09-15
JP2005514323A (ja) 2005-05-19
CA2447673A1 (en) 2002-11-28
ZA200309288B (en) 2005-02-28
US7241885B2 (en) 2007-07-10

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Legal Events

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